Novel semisynthetic triterpenoid AMR-Me inhibits telomerase activity in human leukemic CEM cells and exhibits in vivo antitumor activity against Dalton's lymphoma ascites tumor

Cancer Letters

Volumn 278, Issue 2, 2009, Pages 156-163

  Rabi, Thangaiyan ^a   Banerjee, Sipra ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

AMR Me; Apoptosis; Dalton's lymphoma ascites tumor; hTERT; Leukemia; Telomerase

Indexed keywords

METHYL 25 HYDROXY 3 OXOOLEAN 12 EN 28 OATE; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; TRITERPENOID; UNCLASSIFIED DRUG; VINBLASTINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ASCITES TUMOR; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL GROWTH; CELL VIABILITY; CONTROLLED STUDY; DALTONS LYMPHOMA ASCITES TUMOR; DOWN REGULATION; DRUG STRUCTURE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LEUKEMIA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WEIGHT CHANGE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; ENZYME INHIBITORS; HUMANS; LYMPHOMA; MICE; OLEANOLIC ACID; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; TELOMERASE; TRITERPENES;

AMOORA ROHITUKA; MUS;

EID: 64649104900     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2009.01.003     Document Type: Article

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