Identification of IL-16 as the lymphocyte chemotactic activity in the bronchoalveolar lavage fluid of histamine-challenged asthmatic patients

Journal of Allergy and Clinical Immunology

Volumn 101, Issue 6 II, 1998, Pages 786-792

  Mashikian, Margaret Vallen ^a   Tarpy, Robert E ^a   Saukkonen, Jussi J ^a   Lim, Kaiser G ^a   Fine, Gregg D ^a   Cruikshank, William W ^a   Center, David M ^a,b  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Pulmonary Center   (United States)

Author keywords

Asthma; Bronchoalveolar lavage; Histamine; IL 16; Lymphocyte chemotaxis

Indexed keywords

INTERLEUKIN 16;

ADULT; ALLERGIC ASTHMA; ARTICLE; ATOPY; CHEMOTAXIS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE RELEASE; EOSINOPHILIA; HUMAN; IMMUNOSTIMULATION; LUNG LAVAGE; LYMPHOCYTIC INFILTRATION; MAST CELL DEGRANULATION; PRIORITY JOURNAL; PROVOCATION TEST;

ADULT; ASTHMA; BRONCHIAL PROVOCATION TESTS; BRONCHOALVEOLAR LAVAGE FLUID; CHEMOKINES; CHEMOTAXIS, LEUKOCYTE; FEMALE; HISTAMINE; HUMANS; INTERLEUKIN-16; LYMPHOCYTES; MACROPHAGE INFLAMMATORY PROTEIN-1; MALE; MIDDLE AGED;

EID: 0031816007     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0091-6749(98)70403-8     Document Type: Article

References (23)

1. Djukanovic R, Roche WR, Wilson JW, Beasly CR, Twentyman OP, Holgate ST. Mucosal inflammation in asthma. Am Rev Respir Dis 1990;142:434-57.
2. Pick RB, Richerson HB, Zavala DC, Hunninghake GW. Bronchoalveolar lavage in allergic asthmatics. Am Rev Respir Dis 1987;135:1204-9.
3. Metzger WJ, Zavala D, Richerson HB. Local allergen challenge and bronchoalveolar lavage of allergic asthmatic lungs. Am Rev Respir Dis 1987;135:433-40.
4. Laitinen LA, Laitinen A, Haahtela T. Airway mucosal inflammation even in patients with newly diagnosed asthma. Am Rev Respir Dis 1993;147:697-704.
5. Wilson JW, Djukanovic R, Howarth PH, Holgate ST. Lymphocyte activation in bronchoalveolar lavage and peripheral blood in atopic asthma. Am Rev Respir Dis 1992;145:958-60.
6. Dunill MS. The pathology of asthma with special reference to changes in the bronchial mucosa. J Clin Pathol 1960;13:27-33.
7. Kirby JG, Hargreave FE, Gleich PM, O'Byrne T. Bronchoalveolar cell profiles of asthmatic and nonasthmatic subjects. Am Rev Respir Dis 1987;136:379-83.
8. Robinson DS, Hamid Q, Ying A, Tsicopoulos A. Predominant Th2-like bronchoalveolar T-lymphocyte population in atopic asthma. N Engl J Med 1992;326:298-304.
9. Krishnaswamy G, Liu ML, Su SN, Kumai M, Xiao DG, Marsh SK, et al. Analysis of cytokine transcripts in the bronchoalveolar lavage cells of patients with asthma. Am J Respir Cell Mol Biol 1993;9:279-86.
10. Meltzer SS, Wisiniewski PL, Bleeker ER, Hasday LD. Segmental allergen challenge produces a Th2 pattern of lymphokine secretion in atopic asthma. Am J Respir Crit Care Med 1995;151:A777.
11. Berman J, McFadden R, Cruikshank WW, Center DM, Beer D. Functional characteristics of histamine receptor-bearing mononuclear cells, II: identification and characterization of two histamine-induced human lymphokines that inhibit lymphocyte migration. J Immunol 1984;133:1495-1504.
12. + T cells is independent of transcription and translation. J Immunol 1995;155:2902-10.
13. Bellini A, Yoshimura H, Vitori E, Marini M, Mattoli S. Bronchial epithelial cells of patients with asthma release chemoattractant factors for T lymphocytes. J Allergy Clin Immunol 1993;92:412-24.
14. Cruikshank WW, Berman JS, Theodore AC, Bernardo J, Center DM. Lymphokine activation of T4+ lymphocytes and monocytes. J Immunol 1987;138:3817-25.
15. Cruikshank WW, Center DM, Nisar N, Wu M, Natke B, Kornfeld H, et al. Molecular and functional analysis of a lymphocyte chemoattractant factor: association of biological function with CD4 expression. Proc Natl Acad Sci U S A 1994;91:5109-13.
16. Rand TW, Cruikshank WW, Center DM, Weller PF. CD4-mediated stimulation of human eosinophils: lymphocyte chemoattractant factor and other CD4-binding ligands elicit eosinophil migration. J Exp Med 1991;173:1521-8.
17. Laberge S, Ernst P, Ghaffar O, Cruikshank WW, Center DM, Hamid Q, et al. Bronchial epithelial cells are the major source of interleukin-16 in asthma. Am J Respir Cell Mol Biol 1997;17:193-202.
18. Cruikshank WW, Long A, Kornfeld H, Carroll MP, Holgate ST, Center DM, et al. Early identification of lymphocyte chemoattractant factor IL-16 and macrophage inflammatory protein 1 α in BAL of antigen challenged asthmatics. Am J Respir Cell Mol Biol 1995;13:738-47.
19. Center DM, Cruikshank WW, Berman JS, Beer DJ. Functional characteristics of histamine receptor-bearing mononuclear cells. I: Selective production of lymphocyte chemoattractant lymphokines with histamine used as a ligand. J Immunol 1983;131:1854-9.
20. Moller A, Lippert U, Lessmann G, Kolde G, Hamann K, Czametzki BM, et al. Human mast cells produce IL-8. J Immunol 1993;151:3261-6.
21. Bradding P, Roberts JA, Britten KM, Montefort S, Djukanovic R, Holgate ST, et al. Interleukin-4, -5, and -6 and tumor necrosis factor in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines. Am J Respir Cell Mol Biol 1994;10:471-80.
22. Lim K, Hsiao-Ching W, Bozza PT, Resnick MD. Human eosinophils elaborate the lymphocyte chemoattractants: IL-16 (lymphocyte chemoattractant factor) and RANTES. J Immunol 1996;156:2566-70.
23. Berman JS, Weller PF. Airway eosinophils and lymphocytes in asthma: birds of a feather? Am Rev Respir Dis 1992;145:1246-8.