Novel human histamine H3 receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 22, 2002, Pages 3309-3312

  Shah, Chandra ^a   McAtee, Laura ^a   Breitenbucher, J Guy ^a   Rudolph, Dale ^a   Li, Xiaobing ^a   Lovenberg, Timothy W ^a   Mazur, Curt ^a   Wilson, Sandy J ^a   Carruthers, Nicholas I ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 METHYLIMIDAZOPYRIDINE; ALPHA METHYLHISTAMINE; ANTIHISTAMINIC AGENT; CALCIUM CHANNEL BLOCKING AGENT; CLOZAPINE; DIMAPRIT; HISTAMINE DERIVATIVE; HISTAMINE H3 RECEPTOR; HISTAMINE H3 RECEPTOR ANTAGONIST; IMIDAZOLE; MONOAMINE HISTAMINE; PYRIDINE DERIVATIVE; RECOMBINANT RECEPTOR; SABELUZOLE; THIOPERAMIDE; UNCLASSIFIED DRUG; LIGAND;

ARTICLE; BLOOD BRAIN BARRIER; DOSE RESPONSE; DRUG ANTAGONISM; DRUG BIOAVAILABILITY; DRUG HALF LIFE; DRUG PENETRATION; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; ANIMAL; BIOAVAILABILITY; BRAIN LEVEL; CHEMISTRY; HUMAN; ORAL DRUG ADMINISTRATION; RADIOASSAY; RAT; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; BLOOD-BRAIN BARRIER; BRAIN CHEMISTRY; HISTAMINE ANTAGONISTS; HUMANS; LIGANDS; PYRIDINES; RADIOLIGAND ASSAY; RATS; RECEPTORS, HISTAMINE H3; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037131725     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00738-2     Document Type: Article

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