Induction of S100A4, S100A6, and galectin-1 during the lineage commitment of CD4+CD8+ thymocyte cell line is suppressed by 2,3,7,8-tetrachlorodibenzo-p-dioxin

Toxicology Letters

Volumn 187, Issue 3, 2009, Pages 157-163

  Jeon, Chang Hwan ^a   Kim, Hye Lin ^a   Park, Joo Hung ^a  

^a Changwon National University   (South Korea)

Author keywords

2,3,7,8 Tetrachlorodibenzo p dioxin; CD4+CD8+ thymocyte; Galectin 1; Lineage commitment; S100A4; S100A6

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CALCYCLIN; CALVASCULIN; GALECTIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD4 CD8 RATIO; CELL DIFFERENTIATION; CELL LINEAGE; CELL SUBPOPULATION; CONTROLLED STUDY; IMMUNOSTIMULATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; SPLEEN CELL; THYMOCYTE; UPREGULATION;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CELL LINE, TUMOR; DIOXINS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GALECTIN 1; MICE; MICE, INBRED BALB C; PROTEOMICS; S100 PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; THYMUS GLAND; UP-REGULATION;

EID: 64249147326     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.02.018     Document Type: Article

References (44)

1. Adachi S., and Iwata M. Duration of calcineurin and Erk signals regulates CD4/CD8 lineage commitment of the thymocytes. Cell. Immunol. 215 (2002) 45-53
2. Aliahmad P., and Kaye J. Commitment issues: linking positive selection signals and lineage diversification in the thymus. Immunol. Rev. 209 (2006) 253-273
3. Aliahmad P., and Kaye J. Development of all CD4 T lineages requires nuclear factor TOX. J. Exp. Med. 205 (2008) 245-256
4. Bommhardt U., Basson M.A., Krummrei U., and Zamoyska R. Activation of the extracellular signal-related kinase/mitogen-activated protein kinase pathway discriminates CD4 versus CD8 lineage commitment in the thymus. J. Immunol. 163 (1999) 715-722
5. Bueno O.F., Brandt E.B., Rothenberg M.E., and Molkentin J.D. Defective T cell development and function in calcineurin A beta-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 9398-9403
6. Camby I., Le Mercier M., Lefranc F., and Kiss R. Galectin-1: a small protein with major functions. Glycobiology 16 (2006) 137R-157R
7. Davies M.P.A., Rudland P.S., Robertson L., Parry E.W., et al. Expression of the calcium-binding protein S100S4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumors. Oncogene 13 (1996) 1631-1637
8. Doanto R. Intracellular and extracellular roles of S100 proteins. Microsc. Res. Tech. 60 (2003) 540-551
9. Elad-Sfadia G., Haklai R., Ballan E., Gabius H.J., et al. Galectin-1 augments Ras activation and diverts Ras signals to Raf-1 at the expense of phosphoinositide 3-kinase. J. Biol. Chem. 277 (2002) 37169-37175
10. 2+ release from isolated sarcoplasmic reticulum vesicles. FEBS Lett. 255 (1989) 381-384
11. Fischer C., Sanchez-Ruderisch H., Welzel M., Wiedenmann B., et al. Galectin-1 interacts with the {alpha}5{beta}1 fibronectin receptor to restrict carcinoma cell growth via induction of p21 and p27. J. Biol. Chem. 280 (2005) 37266-37277
12. Germain R.N. T-cell development and the CD4-CD8 lineage decision. Nat. Rev. Immunol. 2 (2002) 309-322
13. + into CD4 and CD8 thymocytes, respectively. Toxicol. Lett. 180 (2008) 189-195
14. Grigorian M., Andresen S., Tulchinsky E., Kriajevska M., et al. Tumor suppressor p53 protein is a new target for the metastasis-associated Mts1/S100A4 protein: functional consequences of their interaction. J. Biol. Chem. 276 (2001) 22699-22708
15. He X., Dave V.P., Zhang Y., Hua X., et al. The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment. Nature 433 (2005) 826-833
16. Hernandez-Hoyos G., Anderson M.K., Wang C., Rothenberg E.V., et al. GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation. Immunity 19 (2003) 83-94
17. Huff J., Lucier G., and Tritscher A. Carcinogenicity of TCDD: experimental, mechanistic, and epidemiologic evidence. Annu. Rev. Pharmacol. Toxicol. 34 (1994) 343-372
18. Ito M., and Kizawa K. Expression of calcium-binding S100 proteins 4 and a6 in regions of the epithelial sac associated with the onset of hair-follicle regeneration. J. Invest. Dermatol. 116 (2001) 956-963
19. Kanamori T., Takakura K., Mandai M., Kariya M., et al. Increased expression of calcium-binding protein S100 in human uterine smooth muscle tumours. Mol. Human Rep. 10 (2004) 35-742
20. Kane L.P., and Weiss A. The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3. Immunol. Rev. 192 (2003) 7-20
21. Kaye J., and Ellenberger D.L. Differentiation of an immature T cell line: a model of thymic positive selection. Cell 71 (1992) 423-435
22. Kerkvliet N.L., and Burleson G.R. Immunotoxicity of TCDD and related halogenated aromatic hydrocarbons. In: Dean J.H., Luster M.I., Munson A.E., and Kimber I. (Eds). Immonotoxicology and Immunopharmacology (1994), Raven Press, NY 97-121
23. Kriajevska M., Tarabykina S., Bronstein I., Maitland N., et al. Metastasis-associated 1(S100A4) protein modulates protein kinas C phosphorylation of the heavy chain of nonmuscle myosin. J. Biol. Chem. 273 (1998) 9852-9856
24. Liu X., and Bosselut R. Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo. Nature Immunol. 5 (2004) 280-288
25. Novitskaya V., Grigorian M., Kriajevska M., Tarabykina S., et al. Oligomeric forms of the metastasis-related Mts1 (S100A4) protein stimulate neuronal differentiation in cultures of rat hippocampal neurons. J. Biol. Chem. 275 (2000) 41278-41286
26. + immature thymocyte line. J. Leukoc. Biol. 81 (2007) 500-508
27. Pace K.E., Hahn H.P., Pang M., Nguyen J.T., et al. CD7 delivers a pro-apoptotic signal during galectin-1-induced T cell death. J. Immunol. 165 (2000) 2331-2334
28. Pages G., Guerin S., Grall D., Bonino F., et al. Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice. Science 286 (1999) 1374-1377
29. Paul Sung K.L., Kuhlman P., Maldonado F., Lollo B.A., Chien S., and Brian A.A. Force contribution of the LFA-1/ICAM-1 complex to T cell activation. J. Cell Sci. 103 (1992) 259-266
30. Perillo N.L., Uittenbogaart C.H., Nguyen J.T., and Baum L.G. Galectin-1, an endogenous lectin produced by thymic epithelial cells, induces apoptosis of human thymocytes. J. Exp. Med. 185 (1997) 1851-1858
31. Poland A., and Knutson J.C. 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annu. Rev. Pharmacol. Toxicol. 22 (1982) 517-554
32. Rodríguez-Borlado L., Barber D.F., Hernández C., Rodríguez-Marcos M.A., et al. Phosphatidylinositol 3-kinase regulates the CD4/CD8 T cell differentiation ratio. J. Immunol. 170 (2003) 4475-4482
33. Sato T., Ohno S., Hayashi T., Sato C., et al. Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes. Immunity 22 (2005) 317-328
34. Schneider M., Hansen J.L., and Sheikh S.P. S100A4: a common mediator of epithelial-mesenchymal transition, fibrosis and regeneration in diseases. J. Mol. Med. 86 (2008) 507-522
35. Shao H., Kono D.H., Chen L.Y., Rubin E.M., and Kaye J. Induction of the early growth response (Egr) family of transcription factors during thymic selection. J. Exp. Med. 185 (1997) 731-744
36. Subrahmanyam G., Rudd C.E., and Schneider H. Association of T cell antigen CD7 with type II phosphatidylinositol-4 kinase, a key component in pathways of inositol phosphate turnover. Eur. J. Immunol. 33 (2003) 46-52
37. Sun G., Liu X., Mercado P., Jenkinson S.R., et al. The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection. Nat. Immunol. 6 (2005) 373-381
38. Swan K.A., Alberola-Ila J., Gross J.A., Appleby M.W., et al. Involvement of p21ras distinguishes positive and negative selection in thymocytes. EMBO J. 14 (1995) 276-285
39. Taniuchi I., Osato M., Egawa T., Sunshine M.J., et al. Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development. Cell 111 (2002) 621-633
40. Temchura V.V., Frericks M., Nacken W., and Esser C. Role of the aryl hydrocarbon receptor in thymocyte emigration in vivo. Eur. J. Immunol. 35 (2005) 2738-2747
41. Tsukumo S., Iwata M., Tohyama C., and Nohara K. Skewed differentiation of thymocytes toward CD8 T cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires activation of the extracellular signal-related kinase pathway. Arch. Toxicol. 76 (2002) 335-343
42. Wildt K.F., Sun G., Grueter B., Fischer M., et al. The transcription factor Zbtb7b promotes CD4 expression by antagonizing Runx-mediated activation of the CD4 silencer. J. Immunol. 179 (2007) 4405-4414
43. Wilkinson B., Chen J.Y., Han P., Rufner K.M., et al. TOX: an HMG box protein implicated in the regulation of thymocyte selection. Nat. Immunol. 3 (2002) 272-280
44. Wilkinson B., and Kaye J. Requirement for sustained MAPK signaling in both CD4 and CD8 lineage commitment: a threshold model. Cell. Immunol. 211 (2001) 86-95