Cutting edge: CD7 delivers a pro-apoptotic signal during galectin-1-induced T cell death

Journal of Immunology

Volumn 165, Issue 5, 2000, Pages 2331-2334

  Pace, K E ^a   Hahn, H P ^a   Pang, M ^a   Nguyen, J T ^a   Baum, L G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD7 ANTIGEN; GALECTIN; CALCIUM; GALECTIN 1; HEMAGGLUTININ; IMMUNOLOGICAL ADJUVANT;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; HUMAN; HUMAN CELL; IMMUNOMODULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE; CELL CULTURE; CELL LINE; CYTOLOGY; IMMUNOLOGY; INNATE IMMUNITY; INTRACELLULAR FLUID; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ADJUVANTS, IMMUNOLOGIC; ANTIGENS, CD7; APOPTOSIS; CALCIUM; CELL DEATH; CELL LINE; GALECTIN 1; HEMAGGLUTININS; HUMANS; IMMUNITY, NATURAL; INTRACELLULAR FLUID; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TUMOR CELLS, CULTURED;

EID: 0034267915     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.5.2331     Document Type: Article

References (36)

1. Galectin-1, an endogenous lectin produced by thymic epithelial cells, induces apoptosis of human thymocytes
2. Apoptosis of T cells mediated by galectin-1
3. Galectin-1 specifically modulates TCR signals to enhance TCR apoptosis, but inhibit IL-2 production and proliferation
4. Induction oft lymphocyte apoptosis: A novel function for galectin-1
5. Galectins and carbohydrates - Versatile mediators of cell adhesion, cell proliferation and cell death
6. Recombinant human β-galactoside binding lectin suppresses clinical and histological signs of experimental autoimmune encephalomyelitis
7. Prevention and therapy with electrolectin of experimental autoimmune myasthenia gravis in rabbits
8. Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosis
9. Galectin-1 exerts immunomodulatory and protective effects on concanavalin A-induced hepatitis in mice
10. Galectin-1 ameliorates the development and severity of GvHD in a murine model
11. Restricted receptor segregation into membrane microdomains occurs on human T cells during apoptosis induced by galectin-1
12. Involvement of CD2 and CD3 in galectin-I induced signaling in human Jurkat T-cells
13. Structure and function of the CD7 molecule
14. Molecular cloning of two CD7 (T-cell leukemia antigen) cDNAs by a COS cell expression system
15. Repression of transcription from the human T-cell leukemia virus type 1 long terminal repeat and cellular gene promoters by wild-type p53
16. 2+ and pH of rat thymocytes in response to galactoside-binding proteins (lectins or immunoglobulins)
17. Cell calcium signaling induced by endogenous lectin carbohydrate interaction in the Jurkat T cell line
18. Appearance of phosphatidylserine on apoptotic cells requires calcium-mediated nonspecific flip-flop and is enhanced by loss of the aminophospholipid translocase
19. Selection of the T cell repertoire
20. Mature T lymphocyte apoptosis - Immune regulation in a dynamic and unpredictable antigenic environment
21. T-cell apoptosis detected in situ during positive and negative selection in the thymus
22. Tyrosine kinase activity associated with the CD7 antigen: Correlation with regulation of T cell integrin function
23. Cross-linking of the T cell-specific accessory molecules CD7 and CD28 modulates T cell adhesion
24. 1 integrin-mediated adhesion to fibronectin
25. Chimeric CD7 monoclonal antibody therapy in rheumatoid arthritis
26. Human mouse chimeric CD7 monoclonal antibody (SDZCHH380) for the prophylaxis of kidney transplant rejection
27. - T helper lymphocytes expansion
28. Expression of the endogenous 14-kDa β-galactoside-binding lectin galectin-1 in normal human skin
29. T-cell lymphoma cell lines (HUT102 and HUT78) established at the National Cancer Institute: History and importance to understanding the biology, clinical features, and therapy of cutaneous T-cell lymphomas (CTCL) and adult T-cell leukemia-lymphomas (ATLL)
30. - T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity
31. CD7-negative T cells represent a separate differentiation pathway in a subset of post-thymic helper T cells
32. Targeted gene disruption of murine CD7
33. Immunologic characterization of CD7-deficient mice
34. Expression of a specific glycosyltransferase enzyme regulates T cell death mediated by galectin-1
35. 13C enriched linear poly-N-acetyllactosamines as ligands for galectin-1
36. A single N-linked glycosylation site is implicated in the regulation of ligand recognition by the I-type lectins CD22 and CD33