Differential expression of GLUT2 in pancreatic islets and kidneys of New and Old World nonhuman primates

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 296, Issue 3, 2009, Pages

  Kramer, Joshua ^a   Moeller, Elisabeth Ludlage ^a   Hachey, Audra ^a   Mansfield, Keith G ^a   Wachtman, Lynn M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Common marmoset; Diabetes mellitus; Streptozotocin

Indexed keywords

GLUCOSE TRANSPORTER 2; INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; LIVER TOXICITY; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STREPTOZOCIN DIABETES; AGING; ANIMAL; BIOSYNTHESIS; BLOOD; CERCOPITHECIDAE; COMPARATIVE STUDY; EXPERIMENTAL DIABETES MELLITUS; GENETICS; GLUCOSE BLOOD LEVEL; KIDNEY; MARMOSET; METABOLISM; PANCREAS ISLET; PATHOLOGY; PLATYRRHINI;

AGING; ANIMALS; BLOOD GLUCOSE; CALLITHRIX; CERCOPITHECIDAE; DIABETES MELLITUS, EXPERIMENTAL; GLUCOSE TRANSPORTER TYPE 2; IMMUNOHISTOCHEMISTRY; INSULIN; ISLETS OF LANGERHANS; KIDNEY; PLATYRRHINI;

EID: 64149127854     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.90694.2008     Document Type: Article

References (25)

1. Campanile N, Rood PP, Yeh P, Casu A, Bottino R, Cooper DK. Acute gastric dilatation after porcine islet transplantation in a cynomolgus monkey - case history and review of the literature. Xenotransplantation 14: 265-270, 2007. (Pubitemid 46699579)
2. Dufrane D, van Steenberghe M, Guiot Y, Goebbels RM, Saliez A, Gianello P. Streptozotocin-induced diabetes in large animals (pigs/primates): role of GLUT2 transporter and beta-cell plasticity. Transplantation 81: 36-45, 2006. (Pubitemid 43122146)
3. Elsner M, Guldbakke B, Tiedge M, Munday R, Lenzen S. Relative importance of transport and alkylation for pancreatic beta-cell toxicity of streptozotocin. Diabetologia 43: 1528-1533, 2000. (Pubitemid 32734859)
4. Elsner M, Tiedge M, Guldbakke B, Munday R, Lenzen S. Importance of the GLUT2 glucose transporter for pancreatic beta cell toxicity of alloxan. Diabetologia 45: 1542-1549, 2002. (Pubitemid 35352048)
5. Elsner M, Tiedge M, Lenzen S. Mechanism underlying resistance of human pancreatic beta cells against toxicity of streptozotocin and alloxan. Diabetologia 46: 1713-1714, 2003. (Pubitemid 38005337)
6. Gai W, Schott-Ohly P, Schulte IM, Walde S, Gleichmann H. Differential target molecules for toxicity induced by streptozotocin and alloxan in pancreatic islets of mice in vitro. Exp Clin Endocrinol Diabetes 112: 29-37, 2004. (Pubitemid 38220430)
7. Hansen B, Tigno X. The rhesus monkey (Macaca mulatta) manifests all features of human type 2 diabetes. In: Animal Models of Diabetes: Frontiers in Research, edited by Shafrir E. Boca Raton, FL: CRC, 2007, p. 251-270.
8. Horvath CJ, Hunt RD, Simon MA, Sehgal PK, Ringler DJ. An immunohistologic study of granulomatous inflammation in SIV-infected rhesus monkeys. J Leukoc Biol 53: 532-540, 1993.
9. Hosokawa M, Dolci W, Thorens B. Differential sensitivity of GLUT1- and GLUT2-expressing beta cells to streptozotocin. Biochem Biophys Res Commun 289: 1114-1117, 2001. (Pubitemid 34076306)
10. im Walde SS, Dohle C, Schott-Ohly P, Gleichmann H. Molecular target structures in alloxan-induced diabetes in mice. Life Sci 71: 1681-1694, 2002.
11. Jonasson O, Jones CW, Bauman A, John E, Manaligod J, Tso MO. The pathophysiology of experimental insulin-deficient diabetes in the monkey. Implications for pancreatic transplantation. Ann Surg 201: 27-39, 1985. (Pubitemid 15157385)
12. Kavanaugh K, Flynn M, Zhang L, Collins J, Rankin S, Sajuthi A, Butler PC, Wagner JD. Development of a nonhuman primate model of type 1 diabetes in African green monkeys (Abstract). JAALAS 46: 126, 2007.
13. Onkamo P, Vaananen S, Karvonen M, Tuomilehto J. Worldwide increase in incidence of type 1 diabetes - the analysis of the data on published incidence trends. Diabetologia 42: 1395-1403, 1999. (Pubitemid 30012309)
14. Purvis A. A composite estimate of primate phylogeny. Philos Trans R Soc Lond B Biol Sci 348: 405-421, 1995.
15. Rerup CC. Drugs producing diabetes through damage of the insulin secreting cells. Pharmacol Rev 22: 485-518, 1970.
16. Rood PP, Bottino R, Balamurugan AN, Smetanka C, Ezzelarab M, Busch J, Hara H, Trucco M, Cooper DK. Induction of diabetes in cynomolgus monkeys with high-dose streptozotocin: adverse effects and early responses. Pancreas 33: 287-292, 2006. (Pubitemid 44470145)
17. Schnedl WJ, Ferber S, Johnson JH, Newgard CB. STZ transport and cytotoxicity. Specific enhancement in GLUT2-expressing cells. Diabetes 43: 1326-1333, 1994.
18. Sloan FA, Bethel MA, Ruiz D Jr, Shea AH, Feinglos MN. The growing burden of diabetes mellitus in the US elderly population. Arch Intern Med 168: 192-199, 2008.
19. Theriault BR, Thistlethwaite JR Jr, Levisetti MG, Wardrip CL, Szot G, Bruce DS, Rilo H, Li X, Gray GS, Bluestone JA, Padrid PA. Induction, maintenance, and reversal of streptozotocin-induced insulindependent diabetes mellitus in the juvenile cynomolgus monkey (Macaca fascilularis). Transplantation 68: 331-337, 1999. (Pubitemid 29384099)
20. Thorens B. Glucose transporters in the regulation of intestinal, renal, and liver glucose fluxes. Am J Physiol Gastrointest Liver Physiol 270: G541-G553, 1996. (Pubitemid 126756548)
21. Thorens B. GLUT2 in pancreatic and extra-pancreatic gluco-detection. Mol Membr Biol 18: 265-273, 2001. (Pubitemid 34052686)
22. Weiss RB. Streptozocin: a review of its pharmacology, efficacy, and toxicity. Cancer Treat Rep 66: 427-438, 1982.
23. White JA, Bolstridge MC, Downing HJ, Helm EH, Klomfass HJ. Diabetogenic drugs in the vervet monkey. S Afr Med J 48: 273-276, 1974.
24. Wood IS, Trayhurn P. Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins. Br J Nutr 89: 3-9, 2003. (Pubitemid 36187532)
25. Yang H, Wright JR Jr. Human beta cells are exceedingly resistant to streptozotocin in vivo. Endocrinology 143: 2491-2495, 2002. (Pubitemid 34701310)