Induction of diabetes in cynomolgus monkeys with high-dose streptozotocin: Adverse effects and early responses

Pancreas

Volumn 33, Issue 3, 2006, Pages 287-292

  Rood, Pleunie P M ^a,b,c   Bottino, Rita ^a   Balamurugan, A N ^b   Smetanka, Cindy ^b   Ezzelarab, Mohamed ^b   Busch, Jamie ^b   Hara, Hidetaka ^b   Trucco, Massimo ^a   Cooper, David K C ^b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Diabetes induction; Nonhuman primates; Streptozotocin; Toxicity; Triphasic response

Indexed keywords

RECOMBINANT HUMAN INSULIN; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEPHROPATHY; DIABETOGENESIS; DRUG MEGADOSE; FEMALE; HYDRATION; HYPERGLYCEMIA; MALE; MONKEY; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEINURIA; STREPTOZOCIN DIABETES; VOMITING;

ANIMALS; C-PEPTIDE; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSE TOLERANCE TEST; INFUSIONS, INTRAVENOUS; MACACA FASCICULARIS; REFERENCE VALUES; STREPTOZOCIN;

EID: 33749149890     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mpa.0000235307.04110.a2     Document Type: Article

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