Mapping of quantitative trait loci affecting behaviour in swine

Animal Genetics

Volumn 40, Issue 4, 2009, Pages 366-376

  Reiner, G ^a   Kohler F ^a   Berge, T ^a   Fischer, R ^a   Hubner Weitz K ^a   Scholl, J ^a   Willems, H ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Behaviour; Disease resistance; Quantitative trait loci; Sarcocystis; Swine

Indexed keywords

ANIMAL; ANIMAL BEHAVIOR; ANIMAL DISEASE; ARTICLE; CHROMOSOME; CHROMOSOME MAP; FEEDING BEHAVIOR; FEMALE; MALE; PARASITOLOGY; PHYSIOLOGY; QUANTITATIVE TRAIT LOCUS; SARCOCYSTIS; SARCOCYSTOSIS; SWINE; SWINE DISEASE;

ANIMALS; BEHAVIOR, ANIMAL; CHROMOSOME MAPPING; CHROMOSOMES, MAMMALIAN; FEEDING BEHAVIOR; FEMALE; MALE; QUANTITATIVE TRAIT LOCI; SARCOCYSTIS; SARCOCYSTOSIS; SWINE; SWINE DISEASES;

ANIMALIA; SARCOCYSTIS; SARCOCYSTIS MIESCHERIANA; SUIDAE; VERTEBRATA;

EID: 64149114622     PISSN: 02689146     EISSN: 13652052     Source Type: Journal    
DOI: 10.1111/j.1365-2052.2008.01847.x     Document Type: Article

References (58)

1. Acakpo-Satchivi L.J., Edelmann W., Sartorius C., Lu B.D., Wahr P.A., Watkins S.C., Metzger J.M., Leinwand L. Kucherlapati R. (1997) Growth and muscle defects in mice lacking adult myosin heavy chain genes. Journal of Cellular Biology 139, 1219 29.
2. Barrows P.L., Prestwood A.K. Green C.E. (1982) Experimental Sarcocystis suicanis infections: disease in growing pigs. American Journal of Veterinary Research 43, 1409 12.
3. Blum K., Sheridan P.J., Wood R.C., Braverman E.R., Chen T.J. Comings D.E. (1995) Dopamine D2 receptor gene variants: association and linkage studies in impulsive-addictive-compulsive behaviour. Pharmacogenetics 5, 121 41.
4. Branson R., Protoczna N., Kral J., Lentes K.U., Hoehe M.R. Horber F. (2003) Binge eating as a major phenotype of melanocortin 4 receptor gene mutations. The New England Journal of Medicine 348, 1096 103.
5. Chen C.C., Chang T. Su H.Y. (2004) Characterization of porcine leptin receptor polymorphisms and their association with reproduction and production traits. Animal Biotechnology 15, 89 102.
6. Churchill G.A. Doerge R.W. (1994) Empirical threshold values for quantitative trait mapping. Genetics 138, 963 71.
7. Dantzer R. (2004) Cytokine-induced sickness behaviour: a neuroimmune response to activation of innate immunity. European Journal of Pharmacology 500, 399 411.
8. Daugschies A.T., Schnieder T., Rommel M. Bickhardt K. (1988) The effects of Sarcocystis miescheriana infections on blood enzymes and weight gain of stress-sensitive and stress-insensitive pigs. Veterinary Parasitology 27, 221 9.
9. Daugschies A., Rommel M. Hoppen H.O. (1989) Prostanoids during acute sarcocystosis in growing pigs. Parasitology Research 76, 115 8.
10. Davis R.J., Shen W., Sandler Y.I., Amoui M., Purcell P., Maas R., Ou C.N., Vogel H., Beaudet A.L. Mardon G. (2001) Dach1 mutant mice bear no gross abnormalities in eye, limb, and brain development and exhibit postnatal lethality. Molecular and Cellular Biology 21, 1484 90.
11. De Almeida R.M., Ferrari P.F., Parmigiani S. Miczek K.A. (2005) Escalated aggressive behavior: dopamine, serotonin and GABA. European Journal of Pharmacology 526, 51 64.
12. De Krom M., Van der Schouw Y.T., Hendriks J., Ophoff R.A., Van Gils C.H., Stolk R.P., Grobbee D.E. Adan R. (2007) Common genetic variations in CCK, leptin, and leptin receptor genes are associated with specific human eating patterns. Diabetes 56, 276 80.
13. De Olveira Peixoto J., Facioni Guimaraes S.E., Lopes P.S., Menck Soares M.A., Vieira Pires A., Gualberto Barbosa M.V., De Almeida Torres R. De Almeida e Silva M. (2006) Associations of leptin gene polymorphisms with production traits in pigs. Journal of Animal Breeding and Genetics 123, 378 83.
14. Desautes C., Bidanel J.P., Milan D., Iannucelli N., Amigues Y., Bourgeois F., Caritez J.C., Renard C., Chevalet C. Mormede P. (2002) Genetic linkage mapping of quantitative trait loci for behavioural and neuroendocrine stress response traits in pigs. Journal of Animal Science 80, 2276 85.
15. Dubey J.P., Speer C.A. Fayer R. (1989) Sarcocystosis of Animal and Man. CRC Press, Boca Raton, FL.
16. Ebstein R.P., Novick O., Umansky R., Priel B., Osher Y., Blaine D., Benett E.R., Nemanov L., Katz M. Belmaker R.H. (1996) Dopamine D4 receptor (DRD4) exon III polymorphism associated with the human personality trait of novelity seeking. Nature Genetics 12, 78 80.
17. Erber M. Geisel O. (1979) Untersuchungen zur Klinik und Pathologie der Sarcocystis suicanis Infektion beim Schwein. Berliner Münchner Tierärztliche Wochenschrift 92, 197 202.
18. Faraone S.V., Perlis R.H., Doyle A.E., Smoller J.W., Gorlanick J.J., Holmgren M.A. Sklar P. (2005) Molecular genetics of attention-deficit/ hyperactivity disorder. Biological Psychiatry 57, 1313 23.
19. Farnier F., Grisart B., Coppieters W. et al. (2002) Simultaneous mining of linkage and linkage disequilibrium to fine map quantitative trait loci in outbred half-sib pedigrees: revisiting the location of a quantitative trait locus with major effect on milk production on bovine chromosome 14. Genetics 161, 275 87.
20. Flint J. (2003) Analysis of quantitative trait loci that influence animal behaviour. Journal of Neurobiology 54, 46 77.
21. Geyer M.A. (1996) Serotonergic functions in arousal and motor activity. Behaviour and Brain Research 73, 31 35.
22. Gill K.J. Boyle A.E. (2005) Quantitative trait loci for novelty/stress-induced locomotor activation in recombinant inbred (RI) and recombinant congenic (RC) strains of mice. Behaviour and Brain Research 161, 113 24.
23. Gutierrez-Gil B., Ball N., Burton D., Haskell M., Williams J.L. Wiener P. (2008) Identification of quantitative trait loci affecting cattle temperament. Journal of Heredity 99, 629 38.
24. Haley C.S., Knott S.A. Elsen J.M. (1994) Mapping quantitative trait loci in crosses between outbred lines using least squares. Genetics 136, 1195 207.
25. Hart B.L. (1988) Biological basis of the behaviour of sick animals. Neuroscience and Biobehavioural Reviews 12, 123 37.
26. Hejjas K., Vas J., Topal J., Szantai E., Ronai Z., Szekely A., Kubiniyi E., Horvath Z., Sasvari-Szekely M. Miklosi A. (2007) Association of polymorphisms in the dopamine D4 receptor gene and the activity-impulsivity endophenotype in dogs. Animal Genetics 38, 629 33.
27. Hiendleder S., Thomsen H., Reinsch N. et al. (2003) Mapping of QTL for body confirmation and behaviour in cattle. Journal of Heredity 94, 496 506.
28. Hinney A., Remschmidt H. Hebebrand J. (2000) Candidate gene polymorphisms in eating disorders. European Journal of Pharmacology 410, 147 59.
29. Holl J.W., Cassady J.P. Johnson R.K. (2004) A genome scan for quantitative trait loci and imprinted regions affecting reproduction in pigs. Journal of Animal Science 82, 3421 9.
30. Hörning B. (1992) Grundsätze artgemäßer Haltung von Schweinen. In : Alternative Konzepte: Artgemäße Schweinehaltung (Ed. by B. Hörning pp. 41 9. Verlag C.F. Müller, Germany.
31. Houston R.D., Haley C.S., Archibald A.L. Rance K.A. (2005) A QTL affecting daily feed intake maps to chromosome 2 in pigs. Mammalian Genome 16, 464 70.
32. Hu Z., Fritz E.R. Reecy J.M. (2007) AnimalQTLdb: a livestock QTL database tool set for positional QTL information mining and beyond. Nucleic Acids Research 35, D604 9.
33. Kim K.S., Larsen N., Short T., Plastow G. Rothschild M.F. (2000) A missense variant of the porcine melanocortin-4 receptor (MC4R). Mammalian Genome 11, 131 5.
34. Konsman J.P., Parnet P. Dantzer R. (2002) Cytokine-induced sickness behaviour: mechanisms and implications. Trends in Neurosciences 25, 154 9.
35. Langley K., Marshall I., Van den Bree M., Thomas H., Owen M., O'Donovan M. Thapar A. (2004) Association of the dopamine D4 receptor gene 7-repeat allele with neurophysiological test performance of children with ADHD. American Journal of Psychiatry 161, 133 8.
36. Leininger M.T., Portocarrero C.P., Schinckel A.P., Spurlock M.E., Bidwell C.A., Nielsen J.N. Houseknecht K.L. (2000) Physiological response to acute endotoxemia in swine: effect of genotype on energy metabolites and leptin. Domestic Animal Endocrinology 18, 71 82.
37. Lowe N., Kirley A., Hawi Z. et al. (2004) Joint analysis of the DRD5 marker concludes association with attention-deficit/hyperactivity disorder confined to the predominantly inattentive and combined subtypes. American Journal of Human Genetics 74, 348 56.
38. Massiera F., Bloch-Faure M., Ceiler D. et al. (2001) Adipose angiotensinogen is involved in adipose tissue growth and blood pressure regulation. FASEB Journal 15, 2727 9.
39. Matsukawa N., Grzesik W.J., Takahashi N., Pandey K.N., Pang S., Yamauchi M. Smithies O. (1999) The natriuretic peptide clearance receptor locally modulates the physiological effects of the natriuretic peptide system. Proceedings of the National Academy of Sciences of the United States of America 96, 7403 8.
40. Mhyre T.R., Chesler E.J., Thiruchelvam M., Lungu C., Cory-Slechta D.A., Fry J.D. Richfield E.K. (2005) Heritability, correlations and in silico mapping of locomotor behaviour and neurochemistry in inbred strains of mice. Genes Brain and Behaviour 4, 209 28.
41. Quilter C.R., Blott S.C., Wilson A.E., Bagga M.R., Sargent C.A., Oliver G.L., Southwood O.I., Gilbert C.L., Mileham A. Affara N.A. (2007) Porcine maternal infanticide as a model for puerperal psychosis. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 144B, 862 8.
42. Reiner G., Eckert J., Peischl T., Bochert S., Jäkel T., Mackenstedt U., Joachim A., Daugschies A. Geldermann H. (2002) Variation in clinical and parasitological traits in Pietrain and Meishan pigs infected with Sarcocystis miescheriana. Veterinary Parasitology 106, 99 113.
43. Reiner G., Hepp S., Hertrampf B., Kliemt D., Mackenstedt U., Daugschies A. Zahner H. (2006) Genetic resistance to Sarcocystis miescheriana in pigs following experimental infection. Veterinary Parasitology 145, 2 10.
44. Reiner G., Kliemt D., Willems H. et al. (2007a) Mapping of quantitative trait loci for resistance/susceptibility to Sarcocystis miescheriana in swine. Genomics 89, 638 46.
45. Reiner G., Fischer R., Hepp S., Berge T., Köhler F. Willems H. (2007b) Quantitative trait loci for red blood cell traits in swine. Animal Genetics 38, 447 52.
46. Reiner G., Fischer R., Hepp S., Berge T., Köhler F. Willems H. (2008) Quantitative trait loci for white blood cell numbers in swine. Animal Genetics 39, 163 8.
47. Reiner G., Clemens N., Fischer R., Köhler F., Berge T., Hepp S. Willems H. (2009) Mapping of quantitative trait loci for clinical-chemical traits in swine. Animal Genetics 40, 57 64.
48. Rommel M., Tenter A.M., Horn K., Daugschies A., Mertens C., Heydorn A.O., Entzeroth R., Eschenbacher K.H. Klein H. (1995) Sarcocystis. In : Guidelines on Techniques in Coccidiosis Research (Ed. by J. Eckert, R. Braun, M.W. Shirley P. Coudert pp. 241 76. Office for Official Publications of the European Communities, Luxembourg.
49. Seaton G., Haley C.S., Knott S.A., Kearsey M. Visscher P.M. (2002) QTL Express: mapping quantitative trait loci in simple and complex pedigrees. Bioinformatics 18, 339 40.
50. Stahly T.S., Williams N.H. Swenson S.G. (1994) Interactive Effects of Immune System Activation and Lean Growth Genotype on Growth of Pigs. ISU Swine Research Report, Ames, IA.
51. Stanley B.G. Leibowitz S.F. (1984) Neuropeptide Y: stimulation of feeding and drinking by injection into the paraventricularis nucleus. Life Sciences 35, 2635 42.
52. Tenter A.M. (1995) Current research on Sarcocystis species of domestic animals. International Journal of Parasitology 25, 1311 30.
53. Trifunovic R. Reilly S. (2006) Medial parabrachial nucleus neurons modulate d-fenfluramine-induced anorexia through 5HT2C receptors. Brain Research 1067, 195 206.
54. Tuchscherer M., Kanitz E., Puppe B. Tuchscherer A. (2006) Early social isolation alters behavioural and physiological responses to an endotoxin challenge in piglets. Hormones and Behaviour 50, 753 61.
55. Van der Lende T., Te Pas M.F., Veerkamp R.F. Lierfs S.C. (2005) Leptin gene polymorphisms and their phenotypic associations. Vitamins and Hormones 71, 373 404.
56. Van Putten G. (1978) Schwein. In : Nutztierethologie (Ed. by H.H. Sambraus pp. 168 212. Parey, Berlin.
57. Winter A., Kramer W., Werner F.A., Kollers S., Kata S., Durstewitz G., Buitkamp J., Womack J.E., Thaller G. Fries R. (2002) Association of a lysine-232/alanine polymorphism in a bovine gene encoding acylCoA:diacylglycerol acyltransferase (DGAT1) with variation at a quantitative trait locus for milk fat content. Proceedings of the National Academy of Sciences of the United States of America 99, 9300 5.
58. Withers D.J., Gutierrez J.S., Towery H. et al. (1998) Disruption of IRS-2 causes type 2 diabetes in mice. Nature 391, 900 4.