Dach1 mutant mice bear no gross abnormalities in eye, limb, and brain development and exhibit postnatal lethality

Molecular and Cellular Biology

Volumn 21, Issue 5, 2001, Pages 1484-1490

  Davis, R J ^a   Shen, W ^a   Sandler, Y I ^a   Amoui, M ^a   Purcell, P ^a   Maas, R ^a   Ou, C N ^a   Vogel, H ^a   Beaudet, A L ^a   Mardon, G ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; BRAIN DEVELOPMENT; DROSOPHILA; EMBRYO DEVELOPMENT; EYE DEVELOPMENT; EYE MALFORMATION; GENETIC CONSERVATION; LETHALITY; LIMB MALFORMATION; MORPHOGENESIS; MOUSE; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION;

ALLELES; ANIMALS; BONE AND BONES; BONE DEVELOPMENT; BRAIN; DNA, COMPLEMENTARY; DROSOPHILA PROTEINS; EMBRYO; EXONS; EXTREMITIES; EYE; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MICE; MICE, KNOCKOUT; MODELS, GENETIC; MUTAGENESIS; MUTATION; NUCLEAR PROTEINS; PHENOTYPE; RETINA;

ANIMALIA; DROSOPHILA DACHSHUND; MAMMALIA; RODENTIA;

EID: 0035135340     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.5.1484-1490.2001     Document Type: Article

References (41)

1. The Drosophila eyes absent gene directs ectopic eye formation in a pathway conserved between flies and vertebrates
2. The eyes absent gene: Genetic control of cell survival and differentiation in the developing Drosophila eye
3. Expression pattern of cSix3, a member of the Six/Sine oculis family of transcription factors
4. Mouse Dac, a novel nuclear factor with homology to Drosophila dachshund shows a dynamic expression in the neural crest, the eye, the neocortex, and the limb bud
5. Cell fate determination in the vertebrate retina
6. Dachshund and Eyes Absent proteins form a complex and function synergistically to induce ectopic eye development in Drosophila
7. The Drosophila sine oculis locus encodes a homeodomaincontaining protein required for the development of the entire visual system
8. Pax6 induces ectopic eyes in a vertebrate
9. Pax genes and organogenesis
10. Role of Olf-1 and Pax-6 transcription factors in neurodevelopment
11. Mouse Dach, a homologue of Drosophila dachshund, is expressed in the developing retina, brain and limbs
12. Genomic structure, evolutionary conservation and Aniridia mutations in the human PAX6 gene
13. The role of Pax-6 in eye and nasal development
14. Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development
15. Mammalian and Drosophila dachshund genes are related to the Ski proto-oncogene and are expressed in eye and limb
16. Central nervous system neuronal migration
17. Site-specific recognition by an isolated DNA-binding domain of the Sine oculis protein
18. Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formation
19. Mouse Small eye results from mutations in a paired-like homeobox-containing gene
20. Six6 (Optx2) is a novel murine Six3-related homeobox gene that demarcates the presumptive pituitary/hypothalamic axis and the ventral optic stalk
21. Molecular cloning and expression of the human and mouse homologues of the Drosophila dachshund gene
22. Genetic control of development of the mushroom bodies, the associative learning centers in the Drosophila brain, by the eyeless, twin of eyeless, and dachshund genes
23. Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice
24. Six3 overexpression initiates the formation of ectopic retina
25. Dachshund encodes a nuclear protein required for normal eye and leg development in Drosophila
26. The retinal determination gene, dachshund, is required for mushroom body cell differentiation
27. Impaired lung branching morphogenesis in the absence of functional EGF receptor
28. Ectopic lens induction in fish in response to the murine homeobox gene Six3
29. Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development
30. The eye-specification proteins So and Eya form a complex and regulate multiple steps in Drosophila eye development
31. Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans
32. Sonic hedgehog mediates the polarizing activity of the ZPA
33. Ectopic eye development in Drosophila induced by directed dachshund expression
34. cis-acting elements that confer lung epithelial cell expression of the CC10 gene
35. Positional cloning and characterization of a paired box- and homeoboxcontaining gene from the Aniridia region
36. Small eye (Sey): Cloning and characterization of the murine homolog of the human Aniridia gene
37. Pax-6, a murine paired box gene, is expressed in the developing CNS
38. Identification of surfactant proteolipid SP-B in human surfactant and fetal lung
39. Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling
40. Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia
41. Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode