Role of Clp proteins in expression of virulence properties of streptococcus mutans

Journal of Bacteriology

Volumn 191, Issue 7, 2009, Pages 2060-2068

  Kajfasz, Jessica K ^a   Martinez, Alaina R ^a   Isamar, Rivera Ramos ^a   Abranches, Jacqueline ^a   Koo, Hyun ^a,b   Quivey Jr , Robert G ^a   Lemos, José A ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF ROCHESTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; GLUCOSE; PROTEIN CLP; SUCROSE; UNCLASSIFIED DRUG; SERINE PROTEINASE;

ANIMAL EXPERIMENT; ARTICLE; AUTOLYSIS; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BIOFILM; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; MUTATIONAL ANALYSIS; NONHUMAN; PH; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STREPTOCOCCUS MUTANS; ANIMAL; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MICROBIAL VIABILITY; MICROBIOLOGY; PATHOGENICITY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; STREPTOCOCCUS INFECTION; TOOTH; VIRULENCE;

ANIMALIA; BACILLUS SUBTILIS; RATTUS; STREPTOCOCCUS MUTANS;

ANIMALS; BACTERIAL PROTEINS; BIOFILMS; HUMANS; MICROBIAL VIABILITY; RATS; RATS, SPRAGUE-DAWLEY; SERINE ENDOPEPTIDASES; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS MUTANS; TOOTH; VIRULENCE;

EID: 64049090426     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.01609-08     Document Type: Article

References (42)

1. Ahn, S. J., and R. A. Burne. 2007. Effects of oxygen on biofilm formation and the AtlA autolysin of Streptococcus mutans. J. Bacteriol. 189:6293-6302.
2. Ajdic, D., W. M. McShan, R. E. McLaughlin, G. Savic, J. Chang, M. B. Carson, C. Primeaux, R. Tian, S. Kenton, H. Jia, S. Lin, Y. Qian, S. Li, H. Zhu, F. Najar, H. Lai, J. White, B. A. Roe, and J. J. Ferretti. 2002. Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen. Proc. Natl. Acad. Sci. USA 99:14434-14439.
3. Banas, J. A., and M. M. Vickerman. 2003. Glucan-binding proteins of the oral streptococci. Crit. Rev. Oral Biol. Med. 14:89-99.
4. Banerjee, A., and I. Biswas. 2008. Markerless multiple-gene- deletion system for Streptococcus mutans. Appl. Environ. Microbiol. 74:2037-2042.
5. Berney, M., H. U. Weilenmann, J. Ihssen, C. Bassin, and T. Egli. 2006. Specific growth rate determines the sensitivity of Escherichia coli to thermal, UVA, and solar disinfection. Appl. Environ. Microbiol. 72:2586-2593.
6. Bottcher, T., and S. A. Sieber. 2008. Beta-lactones as specific inhibitors of ClpP attenuate the production of extracellular virulence factors of Staphylococcus aureus. J. Am. Chem. Soc. 130:14400-14401.
7. Bowen, W. H., S. K. Pearson, and D. A. Young. 1988. The effect of desalivation on coronal and root surface caries in rats. J. Dent. Res. 67:21-23.
8. Brotz-Oesterhelt, H., D. Beyer, H. P. Kroll, R. Endermann, C. Ladel, W. Schroeder, B. Hinzen, S. Raddatz, H. Paulsen, K. Henninger, J. E. Bandow, H. G. Sahl, and H. Labischinski. 2005. Dysregulation of bacterial proteolytic machinery by a new class of antibiotics. Nat. Med. 11:1082-1087.
9. Butler, S. M., R. A. Festa, M. J. Pearce, and K. H. Darwin. 2006. Selfcompartmentalized bacterial proteases and pathogenesis. Mol. Microbiol. 60:553-562.
10. Cao, J., D. Chen, W. Xu, T. Chen, S. Xu, J. Luo, Q. Zhao, B. Liu, D. Wang, X. Zhang, Y. Shan, and Y. Yin. 2007. Enhanced protection against pneumococcal infection elicited by immunization with the combination of PspA, PspC, and ClpP. Vaccine 25:4996-5005.
11. Chatterjee, S. S., H. Hossain, S. Otten, C. Kuenne, K. Kuchmina, S. Machata, E. Domann, T. Chakraborty, and T. Hain. 2006. Intracellular gene expression profile of Listeria monocytogenes. Infect. Immun. 74:1323-1338.
12. Clancy, K. A., S. Pearson, W. H. Bowen, and R. A. Burne. 2000. Characterization of recombinant, ureolytic Streptococcus mutans demonstrates an inverse relationship between dental plaque ureolytic capacity and cariogenicity. Infect. Immun. 68:2621-2629.
13. Deng, D. M., J. M. ten Cate, and W. Crielaard. 2007. The adaptive response of Streptococcus mutans towards oral care products: involvement of the ClpP serine protease. Eur. J. Oral Sci. 115:363-370.
14. Fernandez, A., J. Ogawa, S. Penaud, S. Boudebbouze, D. Ehrlich, M. van de Guchte, and E. Maguin. 2008. Rerouting of pyruvate metabolism during acid adaptation in Lactobacillus bulgaricus. Proteomics 8:3154-3163.
15. Frees, D., A. Chastanet, S. Qazi, K. Sorensen, P. Hill, T. Msadek, and H. Ingmer. 2004. Clp ATPases are required for stress tolerance, intracellular replication and biofilm formation in Staphylococcus aureus. Mol. Microbiol. 54:1445-1462.
16. Frees, D., S. N. Qazi, P. J. Hill, and H. Ingmer. 2003. Alternative roles of ClpX and ClpP in Staphylococcus aureus stress tolerance and virulence. Mol. Microbiol. 48:1565-1578.
17. Frees, D., K. Savijoki, P. Varmanen, and H. Ingmer. 2007. Clp ATPases and ClpP proteolytic complexes regulate vital biological processes in low GC, Gram-positive bacteria. Mol. Microbiol. 63:1285-1295.
18. Frees, D., L. E. Thomsen, and H. Ingmer. 2005. Staphylococcus aureusClpYQ plays a minor role in stress survival. Arch. Microbiol. 183:286-291.
19. Frees, D., P. Varmanen, and H. Ingmer. 2001. Inactivation of a gene that is highly conserved in Gram-positive bacteria stimulates degradation of nonnative proteins and concomitantly increases stress tolerance in Lactococcus lactis. Mol. Microbiol. 41:93-103.
20. Gaillot, O., E. Pellegrini, S. Bregenholt, S. Nair, and P. Berche. 2000. The ClpP serine protease is essential for the intracellular parasitism and virulence of Listeria monocytogenes. Mol. Microbiol. 35:1286-1294.
21. Gerth, U., E. Kruger, I. Derre, T. Msadek, and M. Hecker. 1998. Stress induction of the Bacillus subtilis clpP gene encoding a homologue of the proteolytic component of the Clp protease and the involvement of ClpP and ClpX in stress tolerance. Mol. Microbiol. 28:787-802.
22. Gottesman, S. 2003. Proteolysis in bacterial regulatory circuits. Annu. Rev. Cell Dev. Biol. 19:565-587.
23. Ibrahim, Y. M., A. R. Kerr, N. A. Silva, and T. J. Mitchell. 2005. Contribution of the ATP-dependent protease ClpCP to the autolysis and virulence of Streptococcus pneumoniae. Infect. Immun. 73:730-740.
24. Jenal, U., and R. Hengge-Aronis. 2003. Regulation by proteolysis in bacterial cells. Curr. Opin. Microbiol. 6:163-172.
25. Koo, H., S. K. Pearson, K. Scott-Anne, J. Abranches, J. A. Cury, P. L. Rosalen, Y. K. Park, R. E. Marquis, and W. H. Bowen. 2002. Effects of apigenin and tt-farnesol on glucosyltransferase activity, biofilm viability and caries development in rats. Oral Microbiol. Immunol. 17:337-343.
26. Kwon, H. Y., A. D. Ogunniyi, M. H. Choi, S. N. Pyo, D. K. Rhee, and J. C. Paton. 2004. The ClpP protease of Streptococcus pneumoniae modulates virulence gene expression and protects against fatal pneumococcal challenge. Infect. Immun. 72:5646-5653.
27. Lau, P. C., C. K. Sung, J. H. Lee, D. A. Morrison, and D. G. Cvitkovitch. 2002. PCR ligation mutagenesis in transformable streptococci: application and efficiency. J. Microbiol. Methods 49:193-205.
28. Lee, S. F., A. Progulske-Fox, G. W. Erdos, D. A. Piacentini, G. Y. Ayakawa, P. J. Crowley, and A. S. Bleiweis. 1989. Construction and characterization of isogenic mutants of Streptococcus mutans deficient in major surface protein antigen P1 (I/II). Infect. Immun. 57:3306-3313.
29. Lemos, J. A., and R. A. Burne. 2008. A model of efficiency: stress tolerance by Streptococcus mutans. Microbiology 154:3247-3255.
30. Lemos, J. A., and R. A. Burne. 2002. Regulation and physiological significance of ClpC and ClpP in Streptococcus mutans. J. Bacteriol. 184:6357- 6366.
31. Lemos, J. A., Y. Luzardo, and R. A. Burne. 2007. Physiologic effects of forced down-regulation of dnaK and groEL expression in Streptococcus mutans. J. Bacteriol. 189:1582-1588.
32. Len, A. C., D. W. Harty, and N. A. Jacques. 2004. Stress-responsive proteins are upregulated in Streptococcus mutans during acid tolerance. Microbiology 150:1339-1351.
33. Loo, C. Y., D. A. Corliss, and N. Ganeshkumar. 2000. Streptococcus gordoniibiofilm formation: identification of genes that code for biofilm phenotypes. J. Bacteriol. 182:1374-1382.
34. Nakano, M. M., F. Hajarizadeh, Y. Zhu, and P. Zuber. 2001. Loss-offunction mutations in yjbD result in ClpX- and ClpP-independent competence development of Bacillus subtilis. Mol. Microbiol. 42:383-394.
35. Nakano, S., G. Zheng, M. M. Nakano, and P. Zuber. 2002. Multiple pathways of Spx (YjbD) proteolysis in Bacillus subtilis. J. Bacteriol. 184:3664-3670.
36. Pamp, S. J., D. Frees, S. Engelmann, M. Hecker, and H. Ingmer. 2006. Spx is a global effector impacting stress tolerance and biofilm formation in Staphylococcus aureus. J. Bacteriol. 188:4861-4870.
37. Robertson, G. T., W. L. Ng, R. Gilmour, and M. E. Winkler. 2003. Essentiality of clpX, but not clpP, clpL, clpC, or clpE, in Streptococcus pneumoniaeR6. J. Bacteriol. 185:2961-2966.
38. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
39. Schirmer, E. C., J. R. Glover, M. A. Singer, and S. Lindquist. 1996. HSP100/ Clp proteins: a common mechanism explains diverse functions. Trends Biochem. Sci. 21:289-296.
40. Wall, T., K. Bath, R. A. Britton, H. Jonsson, J. Versalovic, and S. Roos. 2007. The early response to acid shock in Lactobacillus reuteri involves the ClpL chaperone and a putative cell wall-altering esterase. Appl. Environ. Microbiol. 73:3924-3935.
41. Yamashita, Y., W. H. Bowen, R. A. Burne, and H. K. Kuramitsu. 1993. Role of the Streptococcus mutans gtf genes in caries induction in the specificpathogen- free rat model. Infect. Immun. 61:3811-3817.
42. Zuber, P. 2004. Spx-RNA polymerase interaction and global transcriptional control during oxidative stress. J. Bacteriol. 186:1911-1918.