Loss-of-function mutations in yjbD result in ClpX- and ClpP-independent competence development of Bacillus subtilis

Molecular Microbiology

Volumn 42, Issue 2, 2001, Pages 383-394

  Nakano, M M ^a   Hajarizadeh, F ^a   Zhu, Y ^a   Zuber, P ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ENDOPEPTIDASE CLP; ENDOPEPTIDASE CLPX; PENICILLIN BINDING PROTEIN 2A; PROTEIN; PROTEIN COMS; PROTEIN YJBD; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; BACILLUS SUBTILIS; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENETIC CODE; MISSENSE MUTATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULON; STOP CODON; STRAIN DIFFERENCE;

ADENOSINE TRIPHOSPHATASES; BACILLUS SUBTILIS; BACTERIAL PROTEINS; BLOTTING, WESTERN; ENDOPEPTIDASE CLP; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; GENETIC COMPLEMENTATION TEST; HEAT; MOLECULAR CHAPERONES; MUTATION; PHENOTYPE; PHYSICAL CHROMOSOME MAPPING; SERINE ENDOPEPTIDASES; SPORES, BACTERIAL; SUPPRESSION, GENETIC; TRANSCRIPTION FACTORS;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); POSIBACTERIA;

EID: 0034757626     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2001.02639.x     Document Type: Article

References (71)

1. Identification in Listeria monocytogenes of MecA, a homologue of the Bacillus subtilis competence regulatory protein
2. New RNA polymerase sigma factor under spo0 control in Bacillus subtilis
3. Single-column purification of free recombinant proteins using a self-cleavable affinity tag derived from a protein splicing element
4. Identification of comS, a gene of the srfA operon that regulates the establishment of genetic competence in Bacillus subtilis
5. The phosphorylation state of the DegU response regulator acts as a molecular switch allowing either degradative enzyme synthesis or expression of genetic competence in Bacillus subtilis
6. ClpE, a novel type of HSP100 ATPase, is part of the CtsR heat shock regulon of Bacillus subtilis
7. The ftsH gene of Bacillus subtilis is transiently induced after osmotic and temperature upshift
8. Fate of transforming DNA following uptake by competent Bacillus subtilis. I. formation and properties of the donor-recipient complex
9. Growth medium-independent genetic competence mutants of Bacillus subtilis
10. H)
11. Two-component regulators and genetic competence in Bacillus subtilis
12. Effects of metabolic flux on stress response pathways in Lactococcus lactis
13. Complete genome sequence of an M1 strain of Streptococcus pyogenes
14. A target for carbon source-dependent negative regulation of the citB promoter of Bacillus subtilis
15. Inactivation of a gene that is highly conserved in Gram-positive bacteria stimulates degradation of non-native proteins and concomitantly increases stress tolerance in Lactococcus lactis
16. Sequence and transcriptional analysis of clpX, a class-III heat-shock gene of Bacillus subtilis
17. Regulation by proteolysis: Developmental switches
18. Regulation by proteolysis: Energy-dependent proteases and their targets
19. The ClpXP and ClpAP proteases degrade proteins with carboxy-terminal peptide tails added by the SsrA-tagging system
20. Conservation of the regulatory subunit for the Clp ATP-dependent protease in prokaryotes and eukaryotes
21. Antibiotic-resistance cassettes for Bacillus subtilis
22. Plasmids for ectopic integration in Bacillus subtilis
23. Growth stage signal transduction and the requirements for srfA induction in development of competence
24. The regulation of competence transcription factor synthesis constitutes a critical control point in the regulation of competence in Bacillus subtilis
25. The major role of Spo0A in genetic competence is to downregulate abrB, an essential competence gene
26. Inactivation of mecA prevents recovery from the competent state and interferes with cell division and the partitioning of nucleoids in Bacillus subtilis
27. Regulatory inputs for the synthesis of ComK, the competence transcription factor of Bacillus subtilis
28. A small gene, designated comS, located within the coding region of the fourth amino acid-activating domain of srfA, is required for competence development in Bacillus subtilis
29. The pleiotropic response regulator DegU functions as a priming protein in competence development in Bacillus subtilis
30. Degradation of carboxy-terminal-tagged cytoplasmic proteins by the Escherichia coli protease HflB (FtsH)
31. Chaperone rings in protein folding and degradation
32. The ATP-dependent CodWX (HslVU) protease in Bacillus subtilis is an N-terminal serine protease
33. Regulation of competence-specific gene expression by Mec-mediated protein-protein interaction in Bacillus subtilis
34. Sequence and properties of mecA: A negative regulator of genetic competence in Bacillus subtilis
35. The complete genome sequence of the Gram-positive bacterium Bacillus subtilis
36. The ClpX protein of Bacillus subtilis indirectly influences RNA polymerase holoenzyme composition and directly stimulates sigmaH-dependent transcription
37. Plasmid-amplified comS enhances genetic competence and suppresses sinR in Bacillus subtilis
38. Role of Lon and ClpX in the post-translational regulation of a sigma subunit of RNA polymerase required for cellular differentiation of Bacillus subtilis
39. Biochemical and genetic characterization of a competence pheromone from Bacillus subtilis
40. SubtiList: A relational database for the Bacillus subtilis genome
41. ClpP of Bacillus subtilis is required for competence development, motility, degradative enzyme synthesis, growth at high temperature and sporulation
42. Cloning and characterization of srfB: A regulatory gene involved in surfactin production and competence in Bacillus subtilis
43. The primary role of comA in the establishment of the competent state in Bacillus subtilis is to activate the expression of srfA
44. Identification of a genetic locus required for biosynthesis of the lipopeptide antibiotic surfactin in Bacillus subtilis
45. Mutations conferring amino acid residue substitutions in the carboxy-terminal domain of RNA polymerase α can suppress clpX and clpP with respect to developmentally regulated transcription in Bacillus subtilis
46. Deficiency of the initiation events of sporulation in Bacillus subtilis clpP mutant can be suppressed by a lack of the Spo0E protein phosphatase
47. Mutational analysis of ComS: Evidence for the interaction of ComS and MecA in the regulation of competence development in Bacillus subtilis
48. New insights into the ATP-dependent Clp protease: Escherichia coli and beyond
49. Bacillus subtilis CodY represses early-stationary-phase genes by sensing GTP levels
50. Cloning, nucleotide sequence, and expression of the Bacillus subtilis lon gene
51. ComA, a phosphorylated response regulator protein of Bacillus subtilis, binds to the promoter region of srfA
52. Hsp100/Clp proteins: A common mechanism explains diverse functions
53. CodY is required for nutritional repression of Bacillus subtilis genetic competence
54. A gene required for nutritional repression of the Bacillus subtilis dipeptide permease operon
55. Lon and Clp family proteases and chaperones share homologous substrate-recognition domains
56. Convergent sensing pathways mediate response to two extracellular competence factors in Bacillus subtilis
57. Plasmids designed to alter the antibiotic resistance expressed by insertion mutations in Bacillus subtilis, through in vivo recombination
58. Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis
59. Characterization of ylbF, a new gene involved in competence development and sporulation in Bacillus subtilis
60. Biochemical characterization of a molecular switch involving the heat shock protein ClpC, which controls the activity of ComK, the competence transcription factor of Bacillus subtilis
61. Competence in Bacillus subtilis is controlled by regulated proteolysis of a transcription factor
62. comK acts as an autoregulatroy control switch in the signal transduction route to competence in Bacillus subtilis
63. comK encodes the competence transcription factor, the key regulatory protein for competence development in Bacillus subtilis
64. The Clp ATPases define a novel class of molecular chaperones
65. Sequence and transcription mapping of Bacillus subtilis competence genes comB and comA, one of which is related to a family of bacterial regulatory determinants
66. A Bacillus subtilis regulatory gene product for genetic competence and sporulation resembles sensor protein members of the bacterial two-component signal-transduction systems
67. A molecular chaperone, ClpA, functions like DnaK and DnaJ
68. Posttranslational quality control: Folding, refolding, and degrading proteins
69. Redundant in vivo proteolytic activities of Escherichia coli Lon and the ClpYQ (HslUV) protease
70. Role of AbrB in the Spo0A-and Spo0B-dependent utilization of a sporulation promoter in Bacillus subtilis