Characterization of recombinant, ureolytic Streptococcus mutans demonstrates an inverse relationship between dental plaque ureolytic capacity and cariogenicity

Infection and Immunity

Volumn 68, Issue 5, 2000, Pages 2621-2629

  Clancy, K Anne ^a   Pearson, Sylvia ^a   Bowen, William H ^a   Burne, Robert A ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; UREASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEMINERALIZATION; DENTAL CARIES; DENTAL HEALTH; FEMALE; GLUCOSE METABOLISM; NONHUMAN; OPERON; PRIORITY JOURNAL; STRAIN DIFFERENCE; STREPTOCOCCUS MUTANS; TOOTH PLAQUE;

ANIMALS; DENTAL CARIES; DENTAL PLAQUE; FEMALE; GENE EXPRESSION; GENETIC VECTORS; HYDROGEN-ION CONCENTRATION; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINATION, GENETIC; STREPTOCOCCUS MUTANS; UREASE;

EID: 0034059267     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.5.2621-2629.2000     Document Type: Article

References (39)

1. Abelson, D. C., and I. D. Mandel. 1981. The effect of saliva on plaque pH in vivo. J. Dent. Res. 60:1634-1638.
2. Bammann, L. L., W. B. Clark, and R. J. Gibbons. 1978. Impaired colonization of gnotobiotic rats by streptomycin-resistant strains of Streptococcus mutans. Infect. Immun. 22:721-726.
3. Belli, W. A., and R. E. Marquis. 1991. Adaptation of Streptococcus mutans and Enterococcus hirae to acid stress in continuous culture. Appl. Environ. Microbiol. 57:1134-1138.
4. Bender, G. R., and R. E. Marquis. 1987. Membrane ATPases and acid tolerance of Actinomyces viscosus and Lactobacillus casei. Appl. Environ. Microbiol. 53:2124-2128.
5. Biswas, S. D., and I. Kleinberg. 1971. Effect of urea concentration on its utilization, on the pH and the formation of ammonia and carbon dioxide in a human salivary sediment system. Arch. Oral Biol. 16:759-780.
6. Bowden, G. H., and I. R. Hamilton. 1987. Environmental pH as a factor in the competition between strains of the oral streptococci Streptococcus mutans, S. sanguis, and "S. mitior" growing in continuous culture. Can. J. Microbiol. 33:824-327.
7. Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
8. Bradshaw, D. J., A. S. McKee, and P. D. Marsh. 1989. Effects of carbohydrate pulses and pH on population shifts within oral microbial communities. J. Dent. Res. 68:1298-1302.
9. Burne, R. A. 1998. Oral streptococci... products of their environment. J. Dent. Res. 77:445-452.
10. Chen, Y., K. A. Clancy, and R. A. Burne. 1996. Streptococcus salivarius urease: genetic and biochemical characterization and expression in a dental plaque streptococcus. Infect. Immun. 64:585-592.
11. Chen, Y.-Y. M., C. A. Weaver, D. R. Mendelsohn, and R. A. Burne. 1998. Transcriptional regulation of the Streptococcus salivarius 57.I urease operon. J. Bacteriol. 180:5769-5775.
12. Clancy, A., and R. A. Burne. 1997. Construction and characterization of a recombinant ureolytic Streptococcus mutans and its use to demonstrate the relationship of urease activity to pH modulating capacity. FEMS Microbiol. Lett. 151:205-211.
13. Dibdin, G. H., and C. Dawes. 1998. A mathematical model of the influence of salivary urea on the pH of fasted dental plaque and on the changes occurring during a cariogenic challenge. Caries Res. 32:70-74.
14. Flannagan, S. E., L. A. Zitzow, Y. A. Su, and D. B. Clewell. 1994. Nucleotide sequence of the 18-kb conjugative transposon Tn916 from Enterococcus faecalis. Plasmid 32:350-354.
15. Golub, L. M., S. M. Borden, and I. Kleinberg. 1971. Urea content of gingival crevicular fluid and its relationship to periodontal disease in humans. J. Periodontal Res. 6:243-251.
16. Hillman, J. D., A. Chen, and J. L. Snoep. 1996. Genetic and physiological analysis of the lethal effect of L-(+)-lactate dehydrogenase deficiency in Streptococcus mutans: complementation by alcohol dehydrogenase from Zymomonas mobilis. Infect. Immun. 64:4319-4323.
17. Keyes, P. H. 1958. Dental caries in the molar teeth of rats. I. Distribution of lesions induced by high carbohydrate, low-fat diets. J. Dent. Res. 37:1077-1087.
18. Kiska, D. L., and F. L. Macrina. 1994. Genetic regulation of fructosyltransferase in Streptococcus mutans. Infect. Immun. 62:1241-1251.
19. Kleinberg, I. 1967. Effect of urea concentrations on human plaque pH in situ. Arch. Oral Biol. 12:1475-1484.
20. Kleinberg, I., J. A. Kanapka, and D. Craw. 1976. Effect of saliva and salivary factors on the metabolism of the mixed oral flora, p. 433-464. In H. M. Stiles, W. J. Loesche, and T. C. O'Brien (ed.), Microbial aspects of dental caries. Information Retrieval Inc., Washington, D.C.
21. Kubo, S., H. Kubota, Y. Ohnishi, T. Morita, T. Matsuya, and A. Matsushiro. 1993. Expression and secretion of an Arthrobacter dextranase in the oral bacterium Streptococcus gordonii. Infect. Immun. 61:4375-4381.
22. Margolis, H. C., J. H. Duckworth, and E. C. Moreno. 1988. Composition of pooled resting plaque fluid from caries-free and caries susceptible individuals. J. Dent. Res. 67:1468-1475.
23. Marquis, R. E., R. A. Burne, D. T. Parsons, and A. C. Casiano-Colon. 1993. Arginine deiminase and alkali generation in plaque, p. 309-318. In W. H. Bowen and L. A. Tabak (ed.), Cariology for the nineties. University of Rochester Press, Rochester, N.Y.
24. Mobley, H. L. T., M. D. Island, and R. P. Hausinger. 1995. Molecular biology of ureases. Microbiol. Rev. 59:451-480.
25. Morou-Bermudez, E., and R. A. Burne. 1999. Genetic and physiologic characterization of urease of Actinomyces naeslundii. Infect. Immun. 67:504-512.
26. Pearce, E. I., R. G. Schamschula, and M. H. Cooper. 1983. Increases in fluoride, calcium, and phosphate in dental plaque resulting from the use of a mineralizing mouthrinse containing urea and monofluorophosphate. J. Dent. Res. 62:818-820.
27. Pearce, E. I., J. S. Wakefield, and C. H. Sissons. 1991. Therapeutic mineral enrichment of dental plaque visualized by transmission electron microscopy. J. Dent. Res. 70:90-94.
28. Perry, D., and H. K. Kuramitsu. 1989. Genetic linkage among cloned genes of Streptococcus mutans. Infect. Immun. 57:805-809.
29. Peterson, S., J. Woodhead, and J. Crall. 1985. Caries resistance in children with chronic renal failure: plaque pH. salivary pH, and salivary composition. Pediatr. Res. 19:796-799.
30. Salako, N. O., and I. Kleinberg. 1989. Incidence of selected ureolytic bacteria in human dental plaque from sites with different salivary access. Arch. Oral Biol. 34:787-791.
31. Sambrook, J., J. E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
32. Savolainen, H. 1996. Biochemical and clinical aspects of nickel toxicity. Rev. Environ. Health 11:167-173.
33. Singer, D. L., R. Chaterjee, L. Denepitiya, and I. Kleinberg. 1983. A comparison of the acid-base metabolisms of pooled human dental plaque and salivary sediment. Arch. Oral Biol. 28:29-35.
34. Sissons, C. H., T. W. Cutress, and E. I. Pearce. 1985. Kinetics and product stoichiometry of ureolysis by human salivary bacteria and artificial mouth plaques. Arch. Oral Biol. 30:781-790.
35. Stephan, R. M. 1940. Changes in hydrogen-ion concentration on tooth surfaces and in carious lesions. J. Am. Dent. Assoc. 27:718-723.
36. Tanzer, J. M., A. B. Kurasz, and J. Clive. 1985. Inhibition of ecological emergence of mutans streptococci naturally transmitted between rats and consequent caries inhibition by Streptococcus salivarius TOVE-R infection. Infect. Immun. 49:76-83.
37. Theuns, H. M., J. W. van Dijk, F. C. Driessens, and A. Groeneveld. 1984. Effect of the pH of buffer solutions on artificial carious lesion formation in human tooth enamel. Caries Res. 18:7-11.
38. Trieu-Cuot, P., and P. Courvalin. 1983. Nucleotide sequence of the Streptococcus faecalis plasmid gene encoding the 3′5″-aminoglycoside phosphotransferase type III. Gene 23:331-341.
39. Wexler, D. L., J. E. Penders, W. H. Bowen, and R. A. Burne. 1992. Characteristics and cariogenicity of a fructanase-defective Streptococcus mutans strain. Infect. Immun. 60:3673-3681.