-
1
-
-
0036830491
-
-
Akiyama H, Chaboissier MC, Martin JF, Schedl A, de Crombrugghe B. (2002). The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes Dev 16: 28132828.
-
Akiyama H, Chaboissier MC, Martin JF, Schedl A, de Crombrugghe B. (2002). The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes Dev 16: 28132828.
-
-
-
-
2
-
-
0034028836
-
Tumor suppressors and oncogenes in cellular senescence
-
Bringold F, Serrano M. (2000). Tumor suppressors and oncogenes in cellular senescence. Exp Gerontol 35: 317329.
-
(2000)
Exp Gerontol
, vol.35
, pp. 317329
-
-
Bringold, F.1
Serrano, M.2
-
3
-
-
41149150219
-
The Cdk inhibitor p27 in human cancer: Prognostic potential and relevance to anticancer therapy
-
Chu IM, Hengst L, Slingerland JM. (2008). The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy. Nat Rev Cancer 8: 253267.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 253267
-
-
Chu, I.M.1
Hengst, L.2
Slingerland, J.M.3
-
4
-
-
0028131494
-
-
Connor F, Cary PD, Read CM, Preston NS, Driscoll PC, Denny P et al. (1994). DNAb inding and bending properties of the postmeiotically expressed Sry-related protein Sox-5. Nucleic Acids Res 22: 33393346.
-
Connor F, Cary PD, Read CM, Preston NS, Driscoll PC, Denny P et al. (1994). DNAb inding and bending properties of the postmeiotically expressed Sry-related protein Sox-5. Nucleic Acids Res 22: 33393346.
-
-
-
-
5
-
-
0035425048
-
-
Dai C, Celestino JC, Okada Y, Louis DN, Fuller GN, Holland EC. (2001). PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev 15: 19131925.
-
Dai C, Celestino JC, Okada Y, Louis DN, Fuller GN, Holland EC. (2001). PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev 15: 19131925.
-
-
-
-
6
-
-
85177153194
-
-
Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C et al. (1995). Abiomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 92: 93639367.
-
Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C et al. (1995). Abiomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 92: 93639367.
-
-
-
-
8
-
-
0025145238
-
-
Goldstein S. (1990). Replicative senescence: the human fibroblast comes of age. Science 249: 11291133.
-
Goldstein S. (1990). Replicative senescence: the human fibroblast comes of age. Science 249: 11291133.
-
-
-
-
9
-
-
33746919951
-
-
Hagerstrand D, Hesselager G, Achterberg S, Wickenberg Bolin U, Kowanetz M, Kastemar M et al. (2006). Characterization of an imatinib-sensitive subset of high-grade human glioma cultures. Oncogene 25: 49134922.
-
Hagerstrand D, Hesselager G, Achterberg S, Wickenberg Bolin U, Kowanetz M, Kastemar M et al. (2006). Characterization of an imatinib-sensitive subset of high-grade human glioma cultures. Oncogene 25: 49134922.
-
-
-
-
10
-
-
0034020459
-
Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
-
Holland EC, Celestino J, Dai C, Schaefer L, Sawaya RE, Fuller GN. (2000). Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice. Nat Genet 25: 5557.
-
(2000)
Nat Genet
, vol.25
, pp. 5557
-
-
Holland, E.C.1
Celestino, J.2
Dai, C.3
Schaefer, L.4
Sawaya, R.E.5
Fuller, G.N.6
-
11
-
-
40349103691
-
Transcription factor SOX-5 enhances nasopharyngeal carcinoma progression by down-regulating SPARC gene expression
-
Huang DY, Lin YT, Jan PS, Hwang YC, Liang ST, Peng Y et al. (2008). Transcription factor SOX-5 enhances nasopharyngeal carcinoma progression by down-regulating SPARC gene expression. J Pathol 214: 445455.
-
(2008)
J Pathol
, vol.214
, pp. 445455
-
-
Huang, D.Y.1
Lin, Y.T.2
Jan, P.S.3
Hwang, Y.C.4
Liang, S.T.5
Peng, Y.6
-
12
-
-
0028618304
-
-
Jen J, Harper JW, Bigner SH, Bigner DD, Papadopoulos N, Markowitz S et al. (1994). Deletion of p16 and p15 genes in brain tumors. Cancer Res 54: 63536358.
-
Jen J, Harper JW, Bigner SH, Bigner DD, Papadopoulos N, Markowitz S et al. (1994). Deletion of p16 and p15 genes in brain tumors. Cancer Res 54: 63536358.
-
-
-
-
13
-
-
3843115428
-
-
Johansson FK, Brodd J, Eklof C, Ferletta M, Hesselager G, Tiger CF et al. (2004). Identification of candidate cancer-causing genes in mouse brain tumors by retroviral tagging. Proc Natl Acad Sci USA 101: 1133411337.
-
Johansson FK, Brodd J, Eklof C, Ferletta M, Hesselager G, Tiger CF et al. (2004). Identification of candidate cancer-causing genes in mouse brain tumors by retroviral tagging. Proc Natl Acad Sci USA 101: 1133411337.
-
-
-
-
14
-
-
0028121279
-
Acell cycle regulator potentially involved in genesis of many tumor types
-
Kamb A, Gruis NA, Weaver Feldhaus J, Liu Q, Harshman K, Tavtigian SV et al. (1994). Acell cycle regulator potentially involved in genesis of many tumor types. Science 264: 436440.
-
(1994)
Science
, vol.264
, pp. 436440
-
-
Kamb, A.1
Gruis, N.A.2
Weaver Feldhaus, J.3
Liu, Q.4
Harshman, K.5
Tavtigian, S.V.6
-
15
-
-
33646946746
-
Senescence-associated beta-galactosidase is lysosomal betagalactosidase
-
Lee BY, Han JA, Im JS, Morrone A, Johung K, Goodwin EC et al. (2006). Senescence-associated beta-galactosidase is lysosomal betagalactosidase. Aging Cell 5: 187195.
-
(2006)
Aging Cell
, vol.5
, pp. 187195
-
-
Lee, B.Y.1
Han, J.A.2
Im, J.S.3
Morrone, A.4
Johung, K.5
Goodwin, E.C.6
-
16
-
-
0032189223
-
-
Lefebvre V, Li P, de Crombrugghe B. (1998). Anew long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. EMBO J 17: 57185733.
-
Lefebvre V, Li P, de Crombrugghe B. (1998). Anew long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. EMBO J 17: 57185733.
-
-
-
-
17
-
-
0032431028
-
-
Li DM, Sun H. (1998). PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells. Proc Natl Acad Sci USA 95: 1540615411.
-
Li DM, Sun H. (1998). PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells. Proc Natl Acad Sci USA 95: 1540615411.
-
-
-
-
18
-
-
18644376449
-
-
Liang J, Zubovitz J, Petrocelli T, Kotchetkov R, Connor MK, Han K et al. (2002). PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest. Nat Med 8: 11531160.
-
Liang J, Zubovitz J, Petrocelli T, Kotchetkov R, Connor MK, Han K et al. (2002). PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest. Nat Med 8: 11531160.
-
-
-
-
19
-
-
34347207046
-
-
4th edn, International Agency for Research On Cancer IARC, Lyon
-
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK. (2007). WHO Classification of Tumours of the Central Nervous System, 4th edn, International Agency for Research On Cancer (IARC): Lyon.
-
(2007)
WHO Classification of Tumours of the Central Nervous System
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
Cavenee, W.K.4
-
20
-
-
0035916325
-
PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2)
-
Mamillapalli R, Gavrilova N, Mihaylova VT, Tsvetkov LM, Wu H, Zhang H et al. (2001). PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2). Curr Biol 11: 263267.
-
(2001)
Curr Biol
, vol.11
, pp. 263267
-
-
Mamillapalli, R.1
Gavrilova, N.2
Mihaylova, V.T.3
Tsvetkov, L.M.4
Wu, H.5
Zhang, H.6
-
21
-
-
0028275733
-
Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
-
Nobori T, Miura K, Wu DJ, Lois A, Takabayashi K, Carson DA. (1994). Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature 368: 753756.
-
(1994)
Nature
, vol.368
, pp. 753756
-
-
Nobori, T.1
Miura, K.2
Wu, D.J.3
Lois, A.4
Takabayashi, K.5
Carson, D.A.6
-
22
-
-
52949127312
-
-
Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P et al.(2008). An Integrated genomic analysis of human glioblastoma multiforme. Science 321: 18071812.
-
Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P et al.(2008). An Integrated genomic analysis of human glioblastoma multiforme. Science 321: 18071812.
-
-
-
-
23
-
-
0031797532
-
-
Rempel SA, Golembieski WA, Ge S, Lemke N, Elisevich K, Mikkelsen T et al. (1998). SPARC: a signal of astrocytic neoplastic transformation and reactive response in human primary and xenograft gliomas. J Neuropathol Exp Neurol 57: 11121121.
-
Rempel SA, Golembieski WA, Ge S, Lemke N, Elisevich K, Mikkelsen T et al. (1998). SPARC: a signal of astrocytic neoplastic transformation and reactive response in human primary and xenograft gliomas. J Neuropathol Exp Neurol 57: 11121121.
-
-
-
-
24
-
-
35948984195
-
Expression of SoxE and SoxD genes in human gliomas
-
Schlierf B, Friedrich RP, Roerig P, Felsberg J, Reifenberger G, Wegner M. (2007). Expression of SoxE and SoxD genes in human gliomas. Neuropathol Appl Neurobiol 33: 621630.
-
(2007)
Neuropathol Appl Neurobiol
, vol.33
, pp. 621630
-
-
Schlierf, B.1
Friedrich, R.P.2
Roerig, P.3
Felsberg, J.4
Reifenberger, G.5
Wegner, M.6
-
25
-
-
0036829855
-
-
Schultz C, Lemke N, Ge S, Golembieski WA, Rempel SA. (2002). Secreted protein acidic and rich in cysteine promotes glioma invasion and delays tumor growth in vivo. Cancer Res 62: 62706277.
-
Schultz C, Lemke N, Ge S, Golembieski WA, Rempel SA. (2002). Secreted protein acidic and rich in cysteine promotes glioma invasion and delays tumor growth in vivo. Cancer Res 62: 62706277.
-
-
-
-
26
-
-
0000133469
-
-
Sherwood SW, Rush D, Ellsworth JL, Schimke RT. (1988). Defining cellular senescence in IMR-90 cells: a flow cytometric analysis. Proc Natl Acad Sci USA 85: 90869090.
-
Sherwood SW, Rush D, Ellsworth JL, Schimke RT. (1988). Defining cellular senescence in IMR-90 cells: a flow cytometric analysis. Proc Natl Acad Sci USA 85: 90869090.
-
-
-
-
27
-
-
3142713010
-
-
Shih AH, Dai C, Hu X, Rosenblum MK, Koutcher JA, Holland EC. (2004). Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis. Cancer Res 64: 47834789.
-
Shih AH, Dai C, Hu X, Rosenblum MK, Koutcher JA, Holland EC. (2004). Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis. Cancer Res 64: 47834789.
-
-
-
-
28
-
-
0036799377
-
-
Shin I, Yakes FM, Rojo F, Shin NY, Bakin AV, Baselga J et al. (2002). PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization. Nat Med 8: 1451152.
-
Shin I, Yakes FM, Rojo F, Shin NY, Bakin AV, Baselga J et al. (2002). PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization. Nat Med 8: 1451152.
-
-
-
-
29
-
-
33750447322
-
SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function
-
Stolt CC, Schlierf A, Lommes P, Hillgartner S, Werner T, Kosian T et al. (2006). SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell 11: 697709.
-
(2006)
Dev Cell
, vol.11
, pp. 697709
-
-
Stolt, C.C.1
Schlierf, A.2
Lommes, P.3
Hillgartner, S.4
Werner, T.5
Kosian, T.6
-
30
-
-
13044305289
-
-
Sun H, Lesche R, Li DM, Liliental J, Zhang H, Gao J et al. (1999). PTEN modulates cell cycle progression and cell survival by regulatingphosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway. Proc Natl Acad Sci USA 96: 61996204.
-
Sun H, Lesche R, Li DM, Liliental J, Zhang H, Gao J et al. (1999). PTEN modulates cell cycle progression and cell survival by regulatingphosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway. Proc Natl Acad Sci USA 96: 61996204.
-
-
-
-
31
-
-
34648834721
-
-
Tchougounova E, Kastemar M, Brasater D, Holland EC, Westermark B, Uhrbom L. (2007). Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma. Oncogene 26: 62896296.
-
Tchougounova E, Kastemar M, Brasater D, Holland EC, Westermark B, Uhrbom L. (2007). Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma. Oncogene 26: 62896296.
-
-
-
-
32
-
-
33947115905
-
-
Ueda R, Yoshida K, Kawase T, Kawakami Y, Toda M. (2007). Preferential expression and frequent IgG responses of a tumor antigen, SOX5, in glioma patients. Int J Cancer 120: 17041711.
-
Ueda R, Yoshida K, Kawase T, Kawakami Y, Toda M. (2007). Preferential expression and frequent IgG responses of a tumor antigen, SOX5, in glioma patients. Int J Cancer 120: 17041711.
-
-
-
-
33
-
-
17844396912
-
Antibody-based proteomics for human tissue profiling
-
Uhlen M, Ponten F. (2005). Antibody-based proteomics for human tissue profiling. Mol Cell Proteomics 4: 384393.
-
(2005)
Mol Cell Proteomics
, vol.4
, pp. 384393
-
-
Uhlen, M.1
Ponten, F.2
-
34
-
-
0036791177
-
-
Uhrbom L, Dai C, Celestino JC, Rosenblum MK, Fuller GN, Holland EC. (2002). Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt. Cancer Res 62:55515558.
-
Uhrbom L, Dai C, Celestino JC, Rosenblum MK, Fuller GN, Holland EC. (2002). Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt. Cancer Res 62:55515558.
-
-
-
-
35
-
-
16844370694
-
-
Uhrbom L, Kastemar M, Johansson FK, Westermark B, Holland EC. (2005). Cell type-specific tumor suppression by Ink4a and Arf in Kras-induced mouse gliomagenesis. Cancer Res 65: 20652069.
-
Uhrbom L, Kastemar M, Johansson FK, Westermark B, Holland EC. (2005). Cell type-specific tumor suppression by Ink4a and Arf in Kras-induced mouse gliomagenesis. Cancer Res 65: 20652069.
-
-
-
-
36
-
-
18644370396
-
-
Viglietto G, Motti ML, Bruni P, Melillo RM, D'Alessio A, Califano D et al. (2002). Cytoplasmic relocalization and inhibition of the cyclindependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer. Nat Med 8: 11361144.
-
Viglietto G, Motti ML, Bruni P, Melillo RM, D'Alessio A, Califano D et al. (2002). Cytoplasmic relocalization and inhibition of the cyclindependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer. Nat Med 8: 11361144.
-
-
-
-
37
-
-
0033559518
-
-
Wegner M. (1999). From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res 27: 14091420.
-
Wegner M. (1999). From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res 27: 14091420.
-
-
-
-
38
-
-
26944436250
-
From stem cells to neurons and glia: A Soxist's view of neural development
-
Wegner M, Stolt CC. (2005). From stem cells to neurons and glia: a Soxist's view of neural development. Trends Neurosci 28: 583588.
-
(2005)
Trends Neurosci
, vol.28
, pp. 583588
-
-
Wegner, M.1
Stolt, C.C.2
-
39
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg RA. (1995). The retinoblastoma protein and cell cycle control. Cell 81: 323330.
-
(1995)
Cell
, vol.81
, pp. 323330
-
-
Weinberg, R.A.1
-
40
-
-
0037442818
-
p190RhoGAP can act to inhibit PDGF-induced gliomas in mice: A putative tumor suppressor encoded on human chromosome 19q13.3
-
Wolf RM, Draghi N, Liang X, Dai C, Uhrbom L, Eklof C et al. (2003). p190RhoGAP can act to inhibit PDGF-induced gliomas in mice: a putative tumor suppressor encoded on human chromosome 19q13.3. Genes Dev 17: 476487.
-
(2003)
Genes Dev
, vol.17
, pp. 476487
-
-
Wolf, R.M.1
Draghi, N.2
Liang, X.3
Dai, C.4
Uhrbom, L.5
Eklof, C.6
-
41
-
-
0033676762
-
-
Xia Y, Papalopulu N, Vogt PK, Li J. (2000). The oncogenic potential of the high mobility group box protein Sox3. Cancer Res 60: 63036306.
-
Xia Y, Papalopulu N, Vogt PK, Li J. (2000). The oncogenic potential of the high mobility group box protein Sox3. Cancer Res 60: 63036306.
-
-
-
-
42
-
-
0037086081
-
-
Zafarana G, Gillis AJ, van Gurp RJ, Olsson Elstrodt F, Stoop H et al. (2002). Coamplification of DAD-R, SOX5, and EKI1 in human testicular seminomas, with specific overexpression of DADR, correlates with reduced levels of apoptosis and earlier clinical manifestation. Cancer Res 62: 18221831.
-
Zafarana G, Gillis AJ, van Gurp RJ, Olsson PG, Elstrodt F, Stoop H et al. (2002). Coamplification of DAD-R, SOX5, and EKI1 in human testicular seminomas, with specific overexpression of DADR, correlates with reduced levels of apoptosis and earlier clinical manifestation. Cancer Res 62: 18221831.
-
-
-
|