Psychological stress suppresses innate IFN-γ production via glucocorticoid receptor activation: Reversal by the anxiolytic chlordiazepoxide

Brain, Behavior, and Immunity

Volumn 23, Issue 4, 2009, Pages 535-547

  Curtin, Niamh M ^a,b   Boyle, Noreen T ^a   Mills, Kingston H G ^b   Connor, Thomas J ^a  

^a Trinity Biomedical Sciences Institute   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Anxiety; Anxiolytic; Glucocorticoid; IFN ; IL 10; Immunosuppression; Stress

Indexed keywords

CHLORDIAZEPOXIDE; CORTICOSTERONE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUCOCORTICOID RECEPTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 12; LIPOPOLYSACCHARIDE; MIFEPRISTONE; STAT1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION; IMMOBILIZATION STRESS; INNATE IMMUNITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SERUM; SPLEEN; SPLEEN CELL;

ANALYSIS OF VARIANCE; ANIMALS; ANTI-ANXIETY AGENTS; BLOTTING, WESTERN; CELLS, CULTURED; CHLORDIAZEPOXIDE; CORTICOSTERONE; ENZYME-LINKED IMMUNOSORBENT ASSAY; HORMONE ANTAGONISTS; IMMUNOENZYME TECHNIQUES; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-12; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, KNOCKOUT; MIFEPRISTONE; PHOSPHORYLATION; RECEPTORS, GLUCOCORTICOID; RESTRAINT, PHYSICAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPLEEN; STAT1 TRANSCRIPTION FACTOR; STRESS, PSYCHOLOGICAL;

EID: 63449127903     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2009.02.003     Document Type: Article

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