Treatment with Y-40138, a multiple cytokine production modulator, inhibits lipopolysaccharide- or tumour necrosis factor-α-induced production of pro-inflammatory cytokines and augments interleukin-10

Journal of Pharmacy and Pharmacology

Volumn 57, Issue 11, 2005, Pages 1461-1466

  Fukuda, Tetsuko ^a   Hisadome, Masao ^a   Komatsu, Hirotsugu ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CONCANAVALIN A; CYTOKINE RECEPTOR ANTAGONIST; GALACTOSAMINE; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; N (4 (4 (PYRIMIDIN 2 YL)PIPERAZIN 1 YL)METHYL PHENYL)CYCLOPROPYL) ACETAMIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; Y 40138; ACETAMIDE DERIVATIVE; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12; LIPOPOLYSACCHARIDE, E COLI O55 B5; LIPOPOLYSACCHARIDE, E COLI O55-B5; PIPERAZINE DERIVATIVE; Y 39041;

ANIMAL MODEL; ARTICLE; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; FEMALE; LIVER; LIVER INJURY; MOUSE; NONHUMAN; SPLEEN; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; BLOOD; C57BL MOUSE; DOSE RESPONSE; DRUG ANTAGONISM; GENETICS; METABOLISM; MOUSE MUTANT; TIME;

ACETAMIDES; ANIMALS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-12; LIPOPOLYSACCHARIDES; LIVER; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; PIPERAZINES; SPLEEN; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34548860034     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.57.11.0012     Document Type: Article

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