-
1
-
-
33749261118
-
Airway remodelling in asthma: Current understanding and implications for future therapies
-
Tang ML, Wilson JW, Stewart AG, Royce SG. Airway remodelling in asthma: current understanding and implications for future therapies. Pharmacol Ther. 2006;112:474-488.
-
(2006)
Pharmacol Ther
, vol.112
, pp. 474-488
-
-
Tang, M.L.1
Wilson, J.W.2
Stewart, A.G.3
Royce, S.G.4
-
2
-
-
3543146737
-
Parameters associated with persistent airflow obstruction in chronic severe asthma
-
Bumbacea D, Campbell D, Nguyen L, et al. Parameters associated with persistent airflow obstruction in chronic severe asthma. Eur Respir J. 2004;24:122-128.
-
(2004)
Eur Respir J
, vol.24
, pp. 122-128
-
-
Bumbacea, D.1
Campbell, D.2
Nguyen, L.3
-
3
-
-
34247604426
-
Comparison of airway remodeling in acute, subacute, and chronic models of allergic airways disease
-
Locke NR, Royce SG, Wainewright JS, Samuel CS, Tang ML. Comparison of airway remodeling in acute, subacute, and chronic models of allergic airways disease. Am J Respir Cell Mol Biol. 2007;36:625-632.
-
(2007)
Am J Respir Cell Mol Biol
, vol.36
, pp. 625-632
-
-
Locke, N.R.1
Royce, S.G.2
Wainewright, J.S.3
Samuel, C.S.4
Tang, M.L.5
-
5
-
-
0037212774
-
Airway remodeling and long-term decline in lung function in asthma
-
Ten Hacken NH, Postma DS, Timens W. Airway remodeling and long-term decline in lung function in asthma. Curr Opin Pulm Med. 2003;9:9-14.
-
(2003)
Curr Opin Pulm Med
, vol.9
, pp. 9-14
-
-
Ten Hacken, N.H.1
Postma, D.S.2
Timens, W.3
-
6
-
-
0038160034
-
Histopathology of severe childhood asthma: A case series
-
Jenkins HA, Cool C, Szefler SJ, et al. Histopathology of severe childhood asthma: a case series. Chest. 2003;124:32-41.
-
(2003)
Chest
, vol.124
, pp. 32-41
-
-
Jenkins, H.A.1
Cool, C.2
Szefler, S.J.3
-
7
-
-
0033011603
-
The bronchial epithelium as a key regulator of airway inflammation and remodelling in asthma
-
Holgate ST, Lackie PM, Davies DE, Roche WR, Walls AF. The bronchial epithelium as a key regulator of airway inflammation and remodelling in asthma. Clin Exp Allergy. 1999;29(suppl 2):90-95.
-
(1999)
Clin Exp Allergy
, vol.29
, Issue.SUPPL. 2
, pp. 90-95
-
-
Holgate, S.T.1
Lackie, P.M.2
Davies, D.E.3
Roche, W.R.4
Walls, A.F.5
-
8
-
-
0346888342
-
The airway epithelium: Structural and functional properties in health and disease
-
Knight DA, Holgate ST. The airway epithelium: structural and functional properties in health and disease. Respirology. 2003;8:432-446.
-
(2003)
Respirology
, vol.8
, pp. 432-446
-
-
Knight, D.A.1
Holgate, S.T.2
-
9
-
-
14644412828
-
Markers of eosinophilic inflammation and tissue re-modelling in children before clinically diagnosed bronchial asthma
-
Pohunek P, Warner JO, Turzikova J, Kudrmann J, Roche WR. Markers of eosinophilic inflammation and tissue re-modelling in children before clinically diagnosed bronchial asthma. Pediatr Allergy Immunol. 2005; 16:43-51.
-
(2005)
Pediatr Allergy Immunol
, vol.16
, pp. 43-51
-
-
Pohunek, P.1
Warner, J.O.2
Turzikova, J.3
Kudrmann, J.4
Roche, W.R.5
-
10
-
-
0036435872
-
Structural changes of the airway wall impair respiratory function, even in mild asthma
-
Shiba K, Kasahara K, Nakajima H, Adachi M. Structural changes of the airway wall impair respiratory function, even in mild asthma. Chest. 2002;122:1622-1626.
-
(2002)
Chest
, vol.122
, pp. 1622-1626
-
-
Shiba, K.1
Kasahara, K.2
Nakajima, H.3
Adachi, M.4
-
11
-
-
0037115314
-
The relationship of reticular basement membrane thickness to airway wall remodeling in asthma
-
James AL, Maxwell PS, Pearce-Pinto G, Elliot JG, Carroll NG. The relationship of reticular basement membrane thickness to airway wall remodeling in asthma. Am J Respir Crit Care Med. 2001;166: 1590-1595.
-
(2001)
Am J Respir Crit Care Med
, vol.166
, pp. 1590-1595
-
-
James, A.L.1
Maxwell, P.S.2
Pearce-Pinto, G.3
Elliot, J.G.4
Carroll, N.G.5
-
12
-
-
0035509050
-
Reduced airway distensibility, fixed airflow limitation, and airway wall remodeling in asthma [see comment]
-
Ward C, Johns DP, Bish R, et al. Reduced airway distensibility, fixed airflow limitation, and airway wall remodeling in asthma [see comment]. Am J Respir Crit Care Med. 2001;164:1718-1721.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 1718-1721
-
-
Ward, C.1
Johns, D.P.2
Bish, R.3
-
13
-
-
0036187873
-
Correlation between the bronchial subepithelial layer and whole airway wall thickness in patients with asthma
-
Kasahara K, Shiba K, Ozawa T, Okuda K, Adachi M. Correlation between the bronchial subepithelial layer and whole airway wall thickness in patients with asthma. Thorax. 2002;57:242-246.
-
(2002)
Thorax
, vol.57
, pp. 242-246
-
-
Kasahara, K.1
Shiba, K.2
Ozawa, T.3
Okuda, K.4
Adachi, M.5
-
14
-
-
0037974908
-
Immunohisto-chemical classification of the localization of laminin in the thickened bronchial epithelial basement membrane of deceased bronchial asthma patients
-
Saotome A, Kanai N, Nagai T, Yashiro T, Tokudome S. Immunohisto-chemical classification of the localization of laminin in the thickened bronchial epithelial basement membrane of deceased bronchial asthma patients. Respir Med. 2003;97:688-694.
-
(2003)
Respir Med
, vol.97
, pp. 688-694
-
-
Saotome, A.1
Kanai, N.2
Nagai, T.3
Yashiro, T.4
Tokudome, S.5
-
15
-
-
0026051475
-
Fibroblasts and asthma
-
Roche WR. Fibroblasts and asthma. Clin Exp Allergy. 1991;21:545-548.
-
(1991)
Clin Exp Allergy
, vol.21
, pp. 545-548
-
-
Roche, W.R.1
-
17
-
-
0033823661
-
Differential effects of extracellular matrix proteins on human airway smooth muscle cell proliferation and pheno-type
-
Hirst SJ, Twort CH, Lee TH. Differential effects of extracellular matrix proteins on human airway smooth muscle cell proliferation and pheno-type. Am J Respir Cell Mol Biol. 2000;23:335-344.
-
(2000)
Am J Respir Cell Mol Biol
, vol.23
, pp. 335-344
-
-
Hirst, S.J.1
Twort, C.H.2
Lee, T.H.3
-
18
-
-
0034802397
-
The contribution of interleukin (IL)-4 and IL-13 to the epithelial-mesenchymal trophic unit in asthma
-
Richter A, Puddicombe SM, Lordan JL, et al. The contribution of interleukin (IL)-4 and IL-13 to the epithelial-mesenchymal trophic unit in asthma. Am J Respir Cell Mol Biol. 2001;25:385-391.
-
(2001)
Am J Respir Cell Mol Biol
, vol.25
, pp. 385-391
-
-
Richter, A.1
Puddicombe, S.M.2
Lordan, J.L.3
-
19
-
-
2042512329
-
Expression of growth factors by airway epithelial cells in a model of chronic asthma: Regulation and relationship to subepithelial fibrosis
-
Kumar RK, Herbert C, Foster PS. Expression of growth factors by airway epithelial cells in a model of chronic asthma: regulation and relationship to subepithelial fibrosis. Clin Exp Allergy. 2004;34: 567-575.
-
(2004)
Clin Exp Allergy
, vol.34
, pp. 567-575
-
-
Kumar, R.K.1
Herbert, C.2
Foster, P.S.3
-
20
-
-
0032782848
-
Myofibroblasts, I: Paracrine cells important in health and disease
-
Powell DW, Mifflin RC, Valentich JD, Crowe SE, Saada JI, West AB. Myofibroblasts, I: paracrine cells important in health and disease. Am J Physiol. 1999;277:C1-C9.
-
(1999)
Am J Physiol
, vol.277
-
-
Powell, D.W.1
Mifflin, R.C.2
Valentich, J.D.3
Crowe, S.E.4
Saada, J.I.5
West, A.B.6
-
21
-
-
0023025366
-
Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix
-
Ignotz RA, Massague J. Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem. 1986;261:4337-4345.
-
(1986)
J Biol Chem
, vol.261
, pp. 4337-4345
-
-
Ignotz, R.A.1
Massague, J.2
-
22
-
-
85047693849
-
Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics
-
Flood-Page P, Menzies-Gow A, Phipps S, et al. Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. J Clin Invest. 2003;112: 1029 -1036.
-
(2003)
J Clin Invest
, vol.112
, pp. 1029-1036
-
-
Flood-Page, P.1
Menzies-Gow, A.2
Phipps, S.3
-
23
-
-
0024534977
-
Independent regulation of collagenase, 72-kDa progelatinase, and metalloendoproteinase inhibitor expression in human fibroblasts by transforming growth factor-β
-
Overall CM, Wrana JL, Sodek J. Independent regulation of collagenase, 72-kDa progelatinase, and metalloendoproteinase inhibitor expression in human fibroblasts by transforming growth factor-β. J Biol Chem. 1989; 264:1860-1869.
-
(1989)
J Biol Chem
, vol.264
, pp. 1860-1869
-
-
Overall, C.M.1
Wrana, J.L.2
Sodek, J.3
-
24
-
-
0032903716
-
Growth factors secreted by bronchial epithelial cells control myofibroblast proliferation: An in vitro co-culture model of airway remodeling in asthma
-
Zhang S, Smartt H, Holgate ST, Roche WR. Growth factors secreted by bronchial epithelial cells control myofibroblast proliferation: an in vitro co-culture model of airway remodeling in asthma. Lab Invest. 1999;79: 395-405.
-
(1999)
Lab Invest
, vol.79
, pp. 395-405
-
-
Zhang, S.1
Smartt, H.2
Holgate, S.T.3
Roche, W.R.4
-
25
-
-
34447562596
-
Hepatocyte growth factor and other fibroblast secretions modulate the phenotype of human bronchial epithelial cells
-
Myerburg MM, Latoche JD, McKenna EE, et al. Hepatocyte growth factor and other fibroblast secretions modulate the phenotype of human bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2007; 292:L1352-L1360.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.292
-
-
Myerburg, M.M.1
Latoche, J.D.2
McKenna, E.E.3
-
26
-
-
0029690394
-
Regulation of mucociliary differentiation of rat tracheal epithelial cells by type I collagen gel substratum
-
Davenport E, Nettesheim P. Regulation of mucociliary differentiation of rat tracheal epithelial cells by type I collagen gel substratum. Am J Respir Cell Mol Biol. 1996;14:19-26.
-
(1996)
Am J Respir Cell Mol Biol
, vol.14
, pp. 19-26
-
-
Davenport, E.1
Nettesheim, P.2
-
28
-
-
0022357460
-
A serum-free method for culturing normal human bronchial epithelial cells at clonal density
-
Lechner JF, LaVeck MA. A serum-free method for culturing normal human bronchial epithelial cells at clonal density. J Tissue Cult Methods. 1985;9:43-48.
-
(1985)
J Tissue Cult Methods
, vol.9
, pp. 43-48
-
-
Lechner, J.F.1
LaVeck, M.A.2
-
29
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hayflick L, Moorhead PS. The serial cultivation of human diploid cell strains. Exp Cell Res. 1961;25:585-621.
-
(1961)
Exp Cell Res
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
30
-
-
23744449992
-
Matrigel: Basement membrane matrix with biological activity
-
Kleinman HK, Martin GR. Matrigel: basement membrane matrix with biological activity. Semin Cancer Biol. 2005;15:378-386.
-
(2005)
Semin Cancer Biol
, vol.15
, pp. 378-386
-
-
Kleinman, H.K.1
Martin, G.R.2
-
32
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 1983;65:55-63.
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
33
-
-
33750020608
-
Liver fluke-associated and sporadic cholangiocarcinoma: An immunohisto-chemical study of bile duct, peribiliary gland and tumour cell pheno-types
-
Hughes NR, Pairojkul C, Royce SG, Clouston A, Bhathal PS. Liver fluke-associated and sporadic cholangiocarcinoma: an immunohisto-chemical study of bile duct, peribiliary gland and tumour cell pheno-types. J Clin Pathol. 2006;59:1073-1078.
-
(2006)
J Clin Pathol
, vol.59
, pp. 1073-1078
-
-
Hughes, N.R.1
Pairojkul, C.2
Royce, S.G.3
Clouston, A.4
Bhathal, P.S.5
-
34
-
-
0028147478
-
Phenotypic identity of gastric mucous neck cells and mucous cells of cardiac, pyloric, and Brunner's glands
-
Hughes NR, Bhathal PS, Francis DM. Phenotypic identity of gastric mucous neck cells and mucous cells of cardiac, pyloric, and Brunner's glands. J Clin Pathol. 1994;47:53-57.
-
(1994)
J Clin Pathol
, vol.47
, pp. 53-57
-
-
Hughes, N.R.1
Bhathal, P.S.2
Francis, D.M.3
-
35
-
-
23944436914
-
Reciprocal changes in trefoil 1 and 2 expression in stomachs of mice with gastric unit hypertrophy and inflammation
-
Franic TV, van Driel IR, Gleeson PA, Giraud AS, Judd LM. Reciprocal changes in trefoil 1 and 2 expression in stomachs of mice with gastric unit hypertrophy and inflammation. J Pathol. 2005;207:43-52.
-
(2005)
J Pathol
, vol.207
, pp. 43-52
-
-
Franic, T.V.1
van Driel, I.R.2
Gleeson, P.A.3
Giraud, A.S.4
Judd, L.M.5
-
36
-
-
0033977013
-
Epithelial-mesenchymal interactions in the pathogenesis of asthma
-
Holgate ST, Davies DE, Lackie PM, Wilson SJ, Puddicombe SM, Lordan JL. Epithelial-mesenchymal interactions in the pathogenesis of asthma. J Allergy Clin Immunol. 2000;105:193-204.
-
(2000)
J Allergy Clin Immunol
, vol.105
, pp. 193-204
-
-
Holgate, S.T.1
Davies, D.E.2
Lackie, P.M.3
Wilson, S.J.4
Puddicombe, S.M.5
Lordan, J.L.6
-
37
-
-
0025514183
-
Myofibroblasts and subepithelial fibrosis in bronchial asthma
-
Brewster CE, Howarth PH, Djukanovic R, Wilson J, Holgate ST, Roche WR. Myofibroblasts and subepithelial fibrosis in bronchial asthma. Am J Respir Cell Mol Biol. 1990;3:507-511.
-
(1990)
Am J Respir Cell Mol Biol
, vol.3
, pp. 507-511
-
-
Brewster, C.E.1
Howarth, P.H.2
Djukanovic, R.3
Wilson, J.4
Holgate, S.T.5
Roche, W.R.6
-
38
-
-
0033020245
-
Epidermal growth factor system regulates mucin production in airways
-
Takeyama K, Dabbagh K, Lee HM, et al. Epidermal growth factor system regulates mucin production in airways. Proc Natl Acad Sci USA. 1999;96:3081-3086.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3081-3086
-
-
Takeyama, K.1
Dabbagh, K.2
Lee, H.M.3
-
39
-
-
33845792372
-
Allergen induced TFF2 is expressed by mucus-producing airway epithelial cells but is not a major regulator of inflammatory responses in the murine lung
-
Nikolaidis NM, Wang TC, Hogan SP, Rothenberg ME. Allergen induced TFF2 is expressed by mucus-producing airway epithelial cells but is not a major regulator of inflammatory responses in the murine lung. Exp Lung Res. 2006;32:483-497.
-
(2006)
Exp Lung Res
, vol.32
, pp. 483-497
-
-
Nikolaidis, N.M.1
Wang, T.C.2
Hogan, S.P.3
Rothenberg, M.E.4
-
40
-
-
0038077422
-
Collagen-induced resistance to glucocorticoid anti-mitogenic actions: A potential explanation of smooth muscle hyperplasia in the asthmatic remodelled airway
-
Bonacci JV, Harris T, Wilson JW, Stewart AG. Collagen-induced resistance to glucocorticoid anti-mitogenic actions: a potential explanation of smooth muscle hyperplasia in the asthmatic remodelled airway. Br J Pharmacol. 2003;138:1203-1206.
-
(2003)
Br J Pharmacol
, vol.138
, pp. 1203-1206
-
-
Bonacci, J.V.1
Harris, T.2
Wilson, J.W.3
Stewart, A.G.4
-
41
-
-
0037271801
-
Relaxin deficiency in mice is associated with age-related progression of pulmonary fibrosis
-
Samuel CS, Zhao C, Bathgate RA, et al. Relaxin deficiency in mice is associated with age-related progression of pulmonary fibrosis. FASEB J. 2003;17:121-123.
-
(2003)
FASEB J
, vol.17
, pp. 121-123
-
-
Samuel, C.S.1
Zhao, C.2
Bathgate, R.A.3
-
43
-
-
0029838626
-
Cell cultures from bronchial subepithelial myofibroblasts enhance eosinophil survival in vitro
-
Zhang S, Mohammed Q, Burbidge A, Morland CM, Roche WR. Cell cultures from bronchial subepithelial myofibroblasts enhance eosinophil survival in vitro. Eur Respir J. 1996;9:1839-1846.
-
(1996)
Eur Respir J
, vol.9
, pp. 1839-1846
-
-
Zhang, S.1
Mohammed, Q.2
Burbidge, A.3
Morland, C.M.4
Roche, W.R.5
-
44
-
-
66249143091
-
A proteomic approach to mimic fibrosis disease evolvement by an in vitro cell line
-
Malmstrom J, Westergren-Thorsson G, Marko-Varga G. A proteomic approach to mimic fibrosis disease evolvement by an in vitro cell line. Electrophoresis. 2001;22:1776-1784.
-
(2001)
Electrophoresis
, vol.22
, pp. 1776-1784
-
-
Malmstrom, J.1
Westergren-Thorsson, G.2
Marko-Varga, G.3
-
45
-
-
0033258047
-
Inhibition of myofibroblast apoptosis by transforming growth factor beta(1)
-
Zhang HY, Phan SH. Inhibition of myofibroblast apoptosis by transforming growth factor beta(1). Am J Respir Cell Mol Biol. 1999;21:658 -665.
-
(1999)
Am J Respir Cell Mol Biol
, vol.21
, pp. 658-665
-
-
Zhang, H.Y.1
Phan, S.H.2
-
46
-
-
0030751729
-
Bronchial epithelial cells in asthma
-
Campbell AM. Bronchial epithelial cells in asthma. Allergy. 1997;52: 483-489.
-
(1997)
Allergy
, vol.52
, pp. 483-489
-
-
Campbell, A.M.1
-
47
-
-
0032193644
-
Airways remodelling in asthma
-
Vignola AM, Chanez P, Siena L, Chiappara G, Bonsignore G, Bousquet J. Airways remodelling in asthma. Pulm Pharmacol Ther. 1998;11: 359-367.
-
(1998)
Pulm Pharmacol Ther
, vol.11
, pp. 359-367
-
-
Vignola, A.M.1
Chanez, P.2
Siena, L.3
Chiappara, G.4
Bonsignore, G.5
Bousquet, J.6
-
48
-
-
0032779202
-
The epidermal growth factor receptor and its ligand family: Their potential role in repair and remodelling in asthma
-
Davies DE, Polosa R, Puddicombe SM, Richter A, Holgate ST. The epidermal growth factor receptor and its ligand family: their potential role in repair and remodelling in asthma. Allergy. 1999;54:771-783.
-
(1999)
Allergy
, vol.54
, pp. 771-783
-
-
Davies, D.E.1
Polosa, R.2
Puddicombe, S.M.3
Richter, A.4
Holgate, S.T.5
-
49
-
-
34548069381
-
Relaxin plays an important role in the regulation of airway structure and function
-
Samuel CS, Royce SG, Burton MD, Zhao C, Tregear GW, Tang ML. Relaxin plays an important role in the regulation of airway structure and function. Endocrinology. 2007;148:4259 -4266.
-
(2007)
Endocrinology
, vol.148
, pp. 4259-4266
-
-
Samuel, C.S.1
Royce, S.G.2
Burton, M.D.3
Zhao, C.4
Tregear, G.W.5
Tang, M.L.6
-
50
-
-
56149111462
-
Airway hyperresponsiveness in asthma: Lessons from in vitro model systems and animal models
-
Meurs H, Gosens R, Zaagsma J. Airway hyperresponsiveness in asthma: lessons from in vitro model systems and animal models. Eur Respir J. 2008;32:487-502.
-
(2008)
Eur Respir J
, vol.32
, pp. 487-502
-
-
Meurs, H.1
Gosens, R.2
Zaagsma, J.3
-
51
-
-
20444462363
-
Structural changes in the airways in asthma: Observations and consequences
-
Bai TR, Knight DA. Structural changes in the airways in asthma: observations and consequences. Clin Sci (Lond). 2005;108:463-477.
-
(2005)
Clin Sci (Lond)
, vol.108
, pp. 463-477
-
-
Bai, T.R.1
Knight, D.A.2
-
52
-
-
0037317310
-
Pharmacotherapy and airway remodelling in asthma?
-
Beckett PA, Howarth PH. Pharmacotherapy and airway remodelling in asthma? Thorax. 2003;58:163-174.
-
(2003)
Thorax
, vol.58
, pp. 163-174
-
-
Beckett, P.A.1
Howarth, P.H.2
-
53
-
-
33750043230
-
Collagen impairs glucocorticoid actions in airway smooth muscle through integrin signalling
-
Bonacci JV, Schuliga M, Harris T, Stewart AG. Collagen impairs glucocorticoid actions in airway smooth muscle through integrin signalling. Br J Pharmacol. 2006;149:365-373.
-
(2006)
Br J Pharmacol
, vol.149
, pp. 365-373
-
-
Bonacci, J.V.1
Schuliga, M.2
Harris, T.3
Stewart, A.G.4
-
54
-
-
0038132944
-
Impact of extracellular matrix and strain on proliferation of bovine airway smooth muscle
-
Bonacci JV, Harris T, Stewart AG. Impact of extracellular matrix and strain on proliferation of bovine airway smooth muscle. Clin Exp Pharmacol Physiol. 2003;30:324-328.
-
(2003)
Clin Exp Pharmacol Physiol
, vol.30
, pp. 324-328
-
-
Bonacci, J.V.1
Harris, T.2
Stewart, A.G.3
|