Reciprocal changes in trefoil 1 and 2 expression in stomachs of mice with gastric unit hypertrophy and inflammation

Journal of Pathology

Volumn 207, Issue 1, 2005, Pages 43-52

  Franic, T V ^a   van Driel, I R ^b   Gleeson, P A ^b   Giraud, A S ^a   Judd, L M ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Gastrin; Hypergastrinaemia; IL 11; Inflammation; Metaplasia; Trefoil

Indexed keywords

ACID PROTEIN; ANTIBODY; GASTRIN; INTERLEUKIN 11; MESSENGER RNA; STOMACH MUCIN; TREFOIL 1; TREFOIL 2; TREFOIL PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; CELL LINEAGE; CONTROLLED STUDY; GASTRITIS; HYPERTROPHY; MONONUCLEAR CELL; MOUSE; NONHUMAN; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; RNA ANALYSIS; STOMACH MUCUS;

ANIMALS; AUTOIMMUNE DISEASES; CYTOKINES; DISEASE MODELS, ANIMAL; GASTRIC MUCOSA; GASTRINS; GASTRITIS; GENE EXPRESSION REGULATION; H(+)-K(+)-EXCHANGING ATPASE; HYPERPLASIA; HYPERTROPHY; INTERLEUKIN-11; MICE; MICE, INBRED BALB C; MICE, MUTANT STRAINS; MUCINS; MUSCLE PROTEINS; PEPTIDES; RNA, MESSENGER; SPECIES SPECIFICITY;

EID: 23944436914     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1811     Document Type: Article

References (44)

1. Taupin D, Podolsky DK. Trefoil factors: initiators of mucosal healing. Nature Rev Mol Cell Biol 2003;4:721-732.
2. Tran CP, Cook GA, Yeomans ND, Thim L, Giraud AS. Trefoil peptide TFF2 (spasmolytic polypeptide) potently accelerates healing and reduces inflammation in a rat model of colitis. Gut 1999; 44:636-642.
3. Babyatsky MW, deBeaumont M, Thim L, Podolsky DK. Oral trefoil peptides protect against ethanol- and indomethacin-induced gastric injury in rats. Gastroenterology 1996;110:489-497.
4. Playford RJ, Marchbank T, Goodlad RA, Chinery RA, Poulsom R, Hanby AM. Transgenic mice that overexpress the human trefoil peptide pS2 have an increased resistance to intestinal damage. Proc Natl Acad Sci U S A 1996;93:2137-2142.
5. Farrell JJ, Taupin D, Koh TJ, Chen D, Zhao CM, Podolsky DK, et al. TFF2/SP-deficient mice show decreased gastric proliferation, increased acid secretion, and increased susceptibility to NSAID injury. J Clin Invest 2002;109:193-204.
6. Lefebvre O, Chenard MP, Masson R, Linares J, Dierich A, LeMeur M, et al. Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein. Science 1996; 274:259-262.
7. Carvalho R, Kayademir T, Soares P, Canedo P, Sousa S, Oliveira C, et al. Loss of heterozygosity and promoter methylation, but not mutation, may underlie loss of TFF1 in gastric carcinoma. Lab Invest 2002;82:1319-1326.
8. Playford RJ, Marchbank T, Chinery R, Evison R, Pignatelli M, Boulton RA, et al. Human spasmolytic polypeptide is a cytoprotective agent that stimulates cell migration. Gastroenterology 1995;108:108-116.
9. Tomasetto C, Masson R, Linares JL, Wendling C, Lefebvre O, Chenard MP, et al. pS2/TFF1 interacts directly with the VWFC cysteine-rich domains of mucins. Gastroenterology 2000; 118:70-80.
10. Bossenmeyer-Pourie C, Kannan R, Ribieras S, Wendling C, Stoll I, Thim L, et al. The trefoil factor 1 participates in gastrointestinal cell differentiation by delaying G1-S phase transition and reducing apoptosis. J Cell Biol 2002;157:761-770.
11. Karam SM, Tomasetto C, Rio MC. Trefoil factor 1 is required for the commitment programme of mouse oxyntic epithelial progenitors. Gut 2004;53:1408-1415.
12. Giraud AS, Pereira PM, Thim L, Parker LM, Judd LM. TFF-2 inhibits iNOS/NO in monocytes, and nitrated protein in healing colon after colitis. Peptides 2004;25:803-809.
13. Dockray GJ, Varro A, Dimaline R, Wang T. The gastrins: their production and biological activities. Annu Rev Physiol 2001; 63:119-139.
14. Friis-Hansen L, Sundler F, Li Y, Gillespie PJ, Saunders TL, Greenson JK, et al. Impaired gastric acid secretion in gastrin-deficient mice. Am J Physiol 1998;274:G561-G568.
15. Wang TC, Koh TJ, Varro A, Cahill RJ, Dangler CA, Fox JG, et al. Processing and proliferative effects of human progastrin in transgenic mice. J Clin Invest 1996;98:1918-1929.
16. Khan ZE, Wang TC, Cui G, Chi AL, Dimaline R. Transcriptional regulation of the human trefoil factor, TFF1, by gastrin. Gastroenterology 2003;125:510-521.
17. +-adenosine triphosphatase beta subunit is required for normal function, development and membrane structure of mouse parietal cells. Gastroenterology 1999;117:605-618.
18. +-stimulated pNPPase. Gastroenterology 1975; 69:175-189.
19. +-ATPase. In Physiology of the Gastrointestinal Tract, Johnson L (ed). Raven Press: New York, 1987; 865-881.
20. +-ATPase are concordantly targeted by parietal cell autoantibodies associated with autoimmune gastritis. Autoimmunity 1993;16:289-295.
21. Franic TV, Judd LM, Robinson D, Barrett SP, Scarff KL, Gleeson PA, et al. Regulation of gastric epithelial cell development revealed in H(+)/K(+)-ATPase beta-subunit- and gastrin-deficient mice. Am J Physiol Gastrointest Liver Physiol 2001;281:G1502-G1511.
22. Judd LM, Gleeson PA, Toh BH, van Driel IR. Autoimmune gastritis results in disruption of gastric epithelial cell development. Am J Physiol 1999;277:G209-G218.
23. Kubota H, Taguchi O, Suzuki Y, Matsuyama M, Nishizuka Y. Hypertrophic gastritis with hypergastrinemia and protein loss after neonatal thymectomy in mice. Gastroenterol Jpn 1986; 21:122-128.
24. Toh B, van Driel I, Gleeson P. Mechanisms of disease: pernicious anemia. N Engl J Med 1997;337:1441-1448.
25. Franic TV, Judd LM, Nguyen NV, Samuelson LC, Loveland KL, Giraud AS, et al. Growth factors associated with gastric mucosal hypertrophy in autoimmune gastritis. Am J Physiol Gastrointest Liver Physiol 2004;287:G910-G918.
26. Barrett S, Gleeson P, Silva HD, Toh B, Driel IV. Interferon-γ is required during the initiation of an organ-specific autoimmune disease. Eur J Immunol 1996;26:1652-1655.
27. Alderuccio F, Toh BH, Tan SS, Gleeson PA, van Driel IR. An autoimmune disease with multiple molecular targets abrogated by the transgenic expression of a single autoantigen in the thymus. J Exp Med 1993;178:419-426.
28. Cook GA, Familari M, Thim L, Giraud AS. The trefoil peptides TFF2 and TFF3 are expressed in rat lymphoid tissues and participate in the immune response. FEBS Lett 1999;456:155-159.
29. Efstathiou JA, Noda M, Rowan A, Dixon C, Chinery R, Jawhari A, et al. Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin-catenin complexes in human colon carcinoma cells. Proc Natl Acad Sci U S A 1998; 95:3122-3127.
30. Soriano-Izquierdo A, Gironella M, Massaguer A, May FE, Salas A, Sans M, et al. Trefoil peptide TFF2 treatment reduces VCAM-1 expression and leukocyte recruitment in experimental intestinal inflammation. J Leukoc Biol 2004;75:214-223.
31. Graness A, Chwieralski CE, Reinhold D, Thim L, Hoffmann W. Protein kinase C and ERK activation are required for TFF-peptide-stimulated bronchial epithelial cell migration and tumor necrosis factor-alpha-induced interleukin-6 (IL-6) and IL-8 secretion. J Biol Chem 2002;277:18 440-18 446.
32. Fox JG, Sheppard BJ, Dangler CA, Whary MT, Ihrig M, Wang TC. Germ-line p53-targeted disruption inhibits Helicobacter-induced premalignant lesions and invasive gastric carcinoma through down-regulation of Th1 proinflammatory responses. Cancer Res 2002;62:696-702.
33. Judd LM, Alderman BM, Howlett M, Shulkes A, Dow C, Moverley J, et al. Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130. Gastroenterology 2004;126:196-207.
34. Wang TC, Goldenring JR, Dangler C, Ito S, Mueller A, Jeon WK, et al. Mice lacking secretory phospholipase A2 show altered apoptosis and differentiation with Helicobacter felis infection. Gastroenterology 1998;114:675-689.
35. Schmidt PH, Lee JR, Joshi V, Playford RJ, Poulsom R, Wright NA, et al. Identification of a metaplastic cell lineage associated with human gastric adenocarcinoma. Lab Invest 1999; 79:639-646.
36. Yamaguchi H, Goldenring JR, Kaminishi M, Lee JR. Association of spasmolytic polypeptide-expressing metaplasia with carcinogen administration and oxyntic atrophy in rats. Lab Invest 2002; 82:1045-1052.
37. Zavros Y, Rieder G, Ferguson A, Samuelson LC, Merchant JL. Genetic or chemical hypochlorhydria is associated with inflammation that modulates parietal and G-cell populations in mice. Gastroenterology 2002;122:119-133.
38. Martinelli TM, van Driel IR, Alderuccio FA, Gleeson PA, Toh B. Analysis of mononuclear cell infiltrate and cytokine production in murine autoimmune gastritis. Gastroenterology 1996; 110:1791-1802.
39. Tebbutt NC, Giraud AS, Inglese M, Jenkins B, Waring P, Clay FJ, et al. Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice. Nature Med 2002;8:1089-1097.
40. Nomura S, Baxter T, Yamaguchi H, Leys C, Vartapetian AB, Fox JG, et al. Spasmolytic polypeptide expressing metaplasia to preneoplasia in H felis-infected mice. Gastroenterology 2004;127:582-594.
41. Dossinger V, Kayademir T, Blin N, Gott P. Down-regulation of TFF expression in gastrointestinal cell lines by cytokines and nuclear factors. Cell Physiol Biochem 2002;12:197-206.
42. Koh T, Goldenring J, Ito S, Mashimo H, Kopin A, Varro A, et al. Gastrin deficiency results in altered gastric differentiation and decreased colonic proliferation in mice. Gastroenterology 1997;113:1015-1025.
43. Lefebvre O, Wolf C, Kedinger M, Chenard MP, Tomasetto C, Chambon P, et al. The mouse one P-domain (pS2) and two P-domain (mSP) genes exhibit distinct patterns of expression. J Cell Biol 1993;122:191-198.
44. Hanby AM, Poulsom R, Elia G, Singh S, Longcroft JM, Wright NA. The expression of the trefoil peptides pS2 and human spasmolytic polypeptide (hSP) in 'gastric metaplasia' of the proximal duodenum: implications for the nature of 'gastric metaplasia'. J Pathol 1993;169:355-360.