Interaction of pentylsarin analogues with human acetylcholinesterase: A kinetic study

Toxicology Letters

Volumn 187, Issue 2, 2009, Pages 119-123

  Worek, F ^a   Herkert, N M ^a   Koller, M ^a   Aurbek, N ^a   Thiermann, H ^a  

^a BUNDESWEHR INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (Germany)

Author keywords

Acetylcholinesterase; Inhibition; Organophosphate; Oxime; Reactivation; Structure activity relationship

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; ACETYLCHOLINESTERASE; ISOPENTYLSARIN; NEOPENTYLSARIN; OBIDOXIME; ORGANOPHOSPHATE; OXIME; PENTYLSARIN DERIVATIVE; SARIN; SECPENTYLSARIN; UNCLASSIFIED DRUG;

AGING; ARTICLE; DEALKYLATION; DISSOCIATION CONSTANT; ENZYME INHIBITION; ERYTHROCYTE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TOXICOKINETICS;

ACETYLCHOLINESTERASE; CHEMICAL WARFARE AGENTS; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; ERYTHROCYTE MEMBRANE; HUMANS; KINETICS; MALE; OBIDOXIME CHLORIDE; ORGANOPHOSPHORUS COMPOUNDS; PYRIDINIUM COMPOUNDS; SARIN;

EID: 63249091615     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.02.010     Document Type: Article

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