Impaired innate and adaptive immunity to streptococcus pneumoniae and its effect on colonization in an infant mouse model

Infection and Immunity

Volumn 77, Issue 4, 2009, Pages 1613-1622

  Bogaert, Debby ^a,b,c   Weinberger, Daniel ^b   Thompson, Claudette ^b   Lipsitch, Marc ^b   Malley, Richard ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; MACROPHAGE CHEMOATTRACTANT PROTEIN 1; PNEUMOCOCCUS VACCINE; PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; BACTERIAL ANTIGEN; BACTERIUM ANTIBODY; CYTOKINE;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ARTICLE; BACTERIAL COLONIZATION; BLOOD; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CLINICAL EVALUATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; EXPOSURE; IMMUNE RESPONSE; IMMUNIZATION; IN VITRO STUDY; INNATE IMMUNITY; MACROPHAGE; MOUSE; NONHUMAN; POPULATION RESEARCH; PRIORITY JOURNAL; PROTEIN EXPRESSION; STIMULATION; STREPTOCOCCUS PNEUMONIAE; TH17 CELL; ADULT; ANIMAL; C57BL MOUSE; DISEASE MODEL; GROWTH, DEVELOPMENT AND AGING; HETEROZYGOTE; HUMAN; IMMUNITY; IMMUNOLOGY; INFANT; METABOLISM; MICROBIOLOGY; NASOPHARYNX; NEWBORN; PNEUMOCOCCAL INFECTION;

ADULT; ANIMALS; ANIMALS, NEWBORN; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; CARRIER STATE; CYTOKINES; DISEASE MODELS, ANIMAL; HUMANS; IMMUNITY; IMMUNITY, INNATE; INFANT; INFANT, NEWBORN; MACROPHAGES; MICE; MICE, INBRED C57BL; NASOPHARYNX; PNEUMOCOCCAL INFECTIONS; PNEUMOCOCCAL VACCINES; STREPTOCOCCUS PNEUMONIAE;

EID: 63149156268     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00871-08     Document Type: Article

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