-
1
-
-
45749089694
-
Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimer's disease
-
Begum A.N., Jones M.R., Lim G.P., Morihara T., Kim P., Heath D.D., Rock C.L., Pruitt M.A., Yang F., Hudspeth B., Hu S., Faull K.F., Teter B., Cole G.M., and Frautschy S.A. Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimer's disease. J. Pharmacol. Exp. Ther. 326 (2008) 196-208
-
(2008)
J. Pharmacol. Exp. Ther.
, vol.326
, pp. 196-208
-
-
Begum, A.N.1
Jones, M.R.2
Lim, G.P.3
Morihara, T.4
Kim, P.5
Heath, D.D.6
Rock, C.L.7
Pruitt, M.A.8
Yang, F.9
Hudspeth, B.10
Hu, S.11
Faull, K.F.12
Teter, B.13
Cole, G.M.14
Frautschy, S.A.15
-
2
-
-
56349140000
-
Immunohistoblot analysis on whole human hemispheres from normal and Alzheimer diseased brains
-
Beliczai Z., Varszegi S., Gulyas B., Halldin C., Kasa P., and Gulya K. Immunohistoblot analysis on whole human hemispheres from normal and Alzheimer diseased brains. Neurochem. Int. 53 (2008) 181-183
-
(2008)
Neurochem. Int.
, vol.53
, pp. 181-183
-
-
Beliczai, Z.1
Varszegi, S.2
Gulyas, B.3
Halldin, C.4
Kasa, P.5
Gulya, K.6
-
3
-
-
33746358256
-
Human apoB overexpression and a high-cholesterol diet differently modify the brain APP metabolism in the transgenic mouse model of atherosclerosis
-
Bjelik A., Bereczki E., Gonda S., Juhász A., Rimanóczy A., Zana M., Csont T., Pákáski M., Boda K., Ferdinandy P., Dux L., Janka Z., Sántha M., and Kálmán J. Human apoB overexpression and a high-cholesterol diet differently modify the brain APP metabolism in the transgenic mouse model of atherosclerosis. Neurochem. Int. 49 (2006) 393-400
-
(2006)
Neurochem. Int.
, vol.49
, pp. 393-400
-
-
Bjelik, A.1
Bereczki, E.2
Gonda, S.3
Juhász, A.4
Rimanóczy, A.5
Zana, M.6
Csont, T.7
Pákáski, M.8
Boda, K.9
Ferdinandy, P.10
Dux, L.11
Janka, Z.12
Sántha, M.13
Kálmán, J.14
-
4
-
-
33845300510
-
APP mRNA splicing is upregulated in the brain of biglycan transgenic mice
-
Bjelik A., Pákáski M., Berecki E., Gonda S., Juhász A., Rimanóczy A., Zana M., Janka Z., Sántha M., and Kálmán J. APP mRNA splicing is upregulated in the brain of biglycan transgenic mice. Neurochem. Int. 50 (2007) 1-4
-
(2007)
Neurochem. Int.
, vol.50
, pp. 1-4
-
-
Bjelik, A.1
Pákáski, M.2
Berecki, E.3
Gonda, S.4
Juhász, A.5
Rimanóczy, A.6
Zana, M.7
Janka, Z.8
Sántha, M.9
Kálmán, J.10
-
5
-
-
38349092352
-
Calcium dysregulation in Alzheimer's disease
-
Bojarski L., Herms J., and Kuznicki J. Calcium dysregulation in Alzheimer's disease. Neurochem. Int. 52 (2008) 621-633
-
(2008)
Neurochem. Int.
, vol.52
, pp. 621-633
-
-
Bojarski, L.1
Herms, J.2
Kuznicki, J.3
-
6
-
-
0034926291
-
The vanilloid receptor: a molecular gateway to the pain pathway
-
Caterina M.J., and Julius D. The vanilloid receptor: a molecular gateway to the pain pathway. Annu. Rev. Neurosci. 24 (2001) 487-517
-
(2001)
Annu. Rev. Neurosci.
, vol.24
, pp. 487-517
-
-
Caterina, M.J.1
Julius, D.2
-
7
-
-
0030777012
-
The capsaicin receptor: a heat-activated ion channel in the pain pathway
-
Caterina M.J., Schumacher M.A., Tominaga M., Rosen T.A., Levine J.D., and Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389 (1997) 816-824
-
(1997)
Nature
, vol.389
, pp. 816-824
-
-
Caterina, M.J.1
Schumacher, M.A.2
Tominaga, M.3
Rosen, T.A.4
Levine, J.D.5
Julius, D.6
-
8
-
-
0029379605
-
Processing of the beta-amyloid precursor protein and its regulation in Alzheimer's disease
-
Checler F. Processing of the beta-amyloid precursor protein and its regulation in Alzheimer's disease. J. Neurochem. 65 (1995) 1431-1444
-
(1995)
J. Neurochem.
, vol.65
, pp. 1431-1444
-
-
Checler, F.1
-
9
-
-
1542512477
-
Stimulation of beta-amyloid precursor protein alpha-processing by phorbol ester involves calcium and calpain activation
-
Chen M., and Fernandez H.L. Stimulation of beta-amyloid precursor protein alpha-processing by phorbol ester involves calcium and calpain activation. Biochem. Biophys. Res. Commun. 316 (2004) 332-340
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.316
, pp. 332-340
-
-
Chen, M.1
Fernandez, H.L.2
-
10
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski P., and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162 (1987) 156-159
-
(1987)
Anal. Biochem.
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
11
-
-
0033954991
-
Oxidative stress and Alzheimer disease
-
Christen Y. Oxidative stress and Alzheimer disease. Am. J. Clin. Nutr. 71 (2000) 621S-629S
-
(2000)
Am. J. Clin. Nutr.
, vol.71
-
-
Christen, Y.1
-
12
-
-
14944372848
-
NSAID and antioxidant prevention of Alzheimer's disease: lessons from in vitro and animal models
-
Cole G.M., Morihara T., Lim G.P., Yang F., Begum A., and Frautschy S.A. NSAID and antioxidant prevention of Alzheimer's disease: lessons from in vitro and animal models. Ann. N. Y. Acad. Sci. 1035 (2004) 68-84
-
(2004)
Ann. N. Y. Acad. Sci.
, vol.1035
, pp. 68-84
-
-
Cole, G.M.1
Morihara, T.2
Lim, G.P.3
Yang, F.4
Begum, A.5
Frautschy, S.A.6
-
13
-
-
0034527983
-
Metal chelation as a potential therapy for Alzheimer's disease
-
Cuajungco M.P., Fagét K.Y., Huang X., Tanzi R.E., and Bush A.I. Metal chelation as a potential therapy for Alzheimer's disease. Ann. N. Y. Acad. Sci. 920 (2000) 292-304
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.920
, pp. 292-304
-
-
Cuajungco, M.P.1
Fagét, K.Y.2
Huang, X.3
Tanzi, R.E.4
Bush, A.I.5
-
14
-
-
44349191658
-
Antioxidant and iron-binding properties of curcumin, capsaicin, and S-allylcysteine reduce oxidative stress in rat brain homogenate
-
Dairam A., Fogel R., Daya S., and Limson J.L. Antioxidant and iron-binding properties of curcumin, capsaicin, and S-allylcysteine reduce oxidative stress in rat brain homogenate. J. Agric. Food Chem. 56 (2008) 3350-3356
-
(2008)
J. Agric. Food Chem.
, vol.56
, pp. 3350-3356
-
-
Dairam, A.1
Fogel, R.2
Daya, S.3
Limson, J.L.4
-
15
-
-
0036718272
-
Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease
-
Fukumoto H., Cheung B.S., Hyman B.T., and Irizarry M.C. Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease. Arch. Neurol. 59 (2002) 1381-1389
-
(2002)
Arch. Neurol.
, vol.59
, pp. 1381-1389
-
-
Fukumoto, H.1
Cheung, B.S.2
Hyman, B.T.3
Irizarry, M.C.4
-
16
-
-
34547451145
-
Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model
-
Garcia-Allosa M., Borrelli L.A., Rozkalne A., Hyman B.T., and Bacskai B.J. Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model. J. Neurochem. 102 (2007) 1095-1104
-
(2007)
J. Neurochem.
, vol.102
, pp. 1095-1104
-
-
Garcia-Allosa, M.1
Borrelli, L.A.2
Rozkalne, A.3
Hyman, B.T.4
Bacskai, B.J.5
-
17
-
-
33750819632
-
Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease
-
Garcia-Allosa M., Robbins E.M., Zhang-Nunes S.X., Purcell S.M., Betensky R.A., Raju S., Prada C., Greenberg S.M., Bacskai B.J., and Frosch M.P. Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease. Neurobiol. Dis. 24 (2006) 516-524
-
(2006)
Neurobiol. Dis.
, vol.24
, pp. 516-524
-
-
Garcia-Allosa, M.1
Robbins, E.M.2
Zhang-Nunes, S.X.3
Purcell, S.M.4
Betensky, R.A.5
Raju, S.6
Prada, C.7
Greenberg, S.M.8
Bacskai, B.J.9
Frosch, M.P.10
-
18
-
-
0025899041
-
Amyloid deposition as the central event in the aetiology of Alzheimer's disease
-
Hardy J., and Allsop D. Amyloid deposition as the central event in the aetiology of Alzheimer's disease. Trends Pharmacol. Sci. 12 (1991) 383-388
-
(1991)
Trends Pharmacol. Sci.
, vol.12
, pp. 383-388
-
-
Hardy, J.1
Allsop, D.2
-
19
-
-
0026597063
-
Alzheimer's disease: the amyloid cascade hypothesis
-
Hardy J.A., and Higgins G.A. Alzheimer's disease: the amyloid cascade hypothesis. Science 256 (1992) 184-185
-
(1992)
Science
, vol.256
, pp. 184-185
-
-
Hardy, J.A.1
Higgins, G.A.2
-
20
-
-
0017807444
-
A linear Lowry-Folin assay for both water-soluble and sodium dodecyl sulfate-solubilized proteins
-
Hess H.H., Lees M.B., and Derr J.E. A linear Lowry-Folin assay for both water-soluble and sodium dodecyl sulfate-solubilized proteins. Anal. Biochem. 85 (1978) 295-300
-
(1978)
Anal. Biochem.
, vol.85
, pp. 295-300
-
-
Hess, H.H.1
Lees, M.B.2
Derr, J.E.3
-
21
-
-
21744443240
-
Shedding light on ADAM metalloproteinases
-
Huovila A.P., Turner A.J., Pelto-Huikko M., Kärkkäinen I., and Ortiz R.M. Shedding light on ADAM metalloproteinases. Trends Biochem. Sci. 30 (2005) 413-422
-
(2005)
Trends Biochem. Sci.
, vol.30
, pp. 413-422
-
-
Huovila, A.P.1
Turner, A.J.2
Pelto-Huikko, M.3
Kärkkäinen, I.4
Ortiz, R.M.5
-
22
-
-
0033528766
-
Benzolactam (BL) enhances sAPP secretion in fibroblasts and in PC12 cells
-
Ibarreta D., Duchén M., Ma D., Qiao L., Kozikowski A.P., and Etcheberrigaray R. Benzolactam (BL) enhances sAPP secretion in fibroblasts and in PC12 cells. Neuroreport 10 (1999) 1035-1040
-
(1999)
Neuroreport
, vol.10
, pp. 1035-1040
-
-
Ibarreta, D.1
Duchén, M.2
Ma, D.3
Qiao, L.4
Kozikowski, A.P.5
Etcheberrigaray, R.6
-
23
-
-
0025690360
-
Transganglionic degeneration of capsaicin-sensitive C-fiber primary afferent terminals
-
Jancsó G., and Lawson S.N. Transganglionic degeneration of capsaicin-sensitive C-fiber primary afferent terminals. Neuroscience 39 (1990) 501-511
-
(1990)
Neuroscience
, vol.39
, pp. 501-511
-
-
Jancsó, G.1
Lawson, S.N.2
-
24
-
-
0023547071
-
Possible use of capsaicin in pain therapy
-
Jancsó G., and Lynn B. Possible use of capsaicin in pain therapy. C. J. Pain 3 (1987) 123-126
-
(1987)
C. J. Pain
, vol.3
, pp. 123-126
-
-
Jancsó, G.1
Lynn, B.2
-
26
-
-
0002358266
-
Desensitization with capsaicin as a tool for studying the function of pain receptors
-
Lim R.K.S. (Ed), Blackwell Science Inc., Oxford
-
Jancsó N. Desensitization with capsaicin as a tool for studying the function of pain receptors. In: Lim R.K.S. (Ed). Pharmacology of Pain (1968), Blackwell Science Inc., Oxford
-
(1968)
Pharmacology of Pain
-
-
Jancsó, N.1
-
27
-
-
0034720796
-
Regulation of amyloid precursor protein (APP) secretion by protein kinase c alpha in human ntera 2 neurons (NT2N)
-
Jolly-Tornetta C., and Wolf B.A. Regulation of amyloid precursor protein (APP) secretion by protein kinase c alpha in human ntera 2 neurons (NT2N). Biochemistry 39 (2000) 7428-7435
-
(2000)
Biochemistry
, vol.39
, pp. 7428-7435
-
-
Jolly-Tornetta, C.1
Wolf, B.A.2
-
28
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
Kang J., Lemaire H.G., Unterbeck A., Salbaum J.M., Masters C.L., Grzeschik K.H., Multhaup G., Beyreuther K., and Muller-Hill B. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325 (1987) 733-736
-
(1987)
Nature
, vol.325
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.G.2
Unterbeck, A.3
Salbaum, J.M.4
Masters, C.L.5
Grzeschik, K.H.6
Multhaup, G.7
Beyreuther, K.8
Muller-Hill, B.9
-
30
-
-
3242757474
-
Differential involvement of protein kinase C alpha and epsilon in the regulated secretion of soluble amyloid precursor protein
-
Lanni C., Mazzucchelli M., Porrello E., Govoni S., and Racchi M. Differential involvement of protein kinase C alpha and epsilon in the regulated secretion of soluble amyloid precursor protein. Eur. J. Biochem. 271 (2004) 3068-3075
-
(2004)
Eur. J. Biochem.
, vol.271
, pp. 3068-3075
-
-
Lanni, C.1
Mazzucchelli, M.2
Porrello, E.3
Govoni, S.4
Racchi, M.5
-
31
-
-
12144286502
-
Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients
-
Li R., Lindholm K., Yang L.B., Yue X., Citron M., Yan R., Beach T., Sue L., Sabbagh M., Cai H., Wong P., Price D., and Shen Y. Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 3632-3637
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 3632-3637
-
-
Li, R.1
Lindholm, K.2
Yang, L.B.3
Yue, X.4
Citron, M.5
Yan, R.6
Beach, T.7
Sue, L.8
Sabbagh, M.9
Cai, H.10
Wong, P.11
Price, D.12
Shen, Y.13
-
32
-
-
0031394645
-
Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin
-
Lin J.K., Chen Y.C., Huang Y.T., and Lin-Shiau S.Y. Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin. J. Cell Biochem. Suppl. 28-29 (1997) 39-48
-
(1997)
J. Cell Biochem. Suppl.
, vol.28-29
, pp. 39-48
-
-
Lin, J.K.1
Chen, Y.C.2
Huang, Y.T.3
Lin-Shiau, S.Y.4
-
34
-
-
33846531680
-
Modulation of proteine kinase C by curcumin, inhibition and activation switched by calcium ions
-
Mahmmoud Y.A. Modulation of proteine kinase C by curcumin, inhibition and activation switched by calcium ions. Br. J. Pharmacol. 150 (2007) 200-208
-
(2007)
Br. J. Pharmacol.
, vol.150
, pp. 200-208
-
-
Mahmmoud, Y.A.1
-
35
-
-
37349100145
-
Hypolipidemic and antioxidant effects of dietary curcumin and capsaicin in induced hypercholesterolemic rats
-
Manjunatha H., and Srinivasan K. Hypolipidemic and antioxidant effects of dietary curcumin and capsaicin in induced hypercholesterolemic rats. Lipids 42 (2007) 1133-1142
-
(2007)
Lipids
, vol.42
, pp. 1133-1142
-
-
Manjunatha, H.1
Srinivasan, K.2
-
36
-
-
39549119848
-
Natural antioxidants in Alzheimer's disease
-
Mancuso C., Bates T.E., Butterfield D.A., Calafato S., Cornelius C., De Lorenzo A., Dinkova Kostova A.T., and Calabrese V. Natural antioxidants in Alzheimer's disease. Expert. Opin. Investig. Drugs 16 (2007) 1921-1931
-
(2007)
Expert. Opin. Investig. Drugs
, vol.16
, pp. 1921-1931
-
-
Mancuso, C.1
Bates, T.E.2
Butterfield, D.A.3
Calafato, S.4
Cornelius, C.5
De Lorenzo, A.6
Dinkova Kostova, A.T.7
Calabrese, V.8
-
37
-
-
36849023935
-
Neurosecretases provide strategies to treat sporadic and familial Alzheimer disorders
-
Marks N., and Berg M.J. Neurosecretases provide strategies to treat sporadic and familial Alzheimer disorders. Neurochem. Int. 52 (2008) 184-215
-
(2008)
Neurochem. Int.
, vol.52
, pp. 184-215
-
-
Marks, N.1
Berg, M.J.2
-
38
-
-
60949111629
-
Nicotinic receptor agonists and antagonists increase sAPPalpha secretion and decrease Abeta levels in vitro
-
(Epub ahead of print)
-
Mousavi M., and Hellström-Lindahl E. Nicotinic receptor agonists and antagonists increase sAPPalpha secretion and decrease Abeta levels in vitro. Neurochem. Int. (2009) (Epub ahead of print)
-
(2009)
Neurochem. Int.
-
-
Mousavi, M.1
Hellström-Lindahl, E.2
-
39
-
-
4644266613
-
The role of the vanilloid (capsaicin) receptor (TRPV1) in physiology and pathology
-
Nagy I., Sántha P., Jancsó G., and Urbán L. The role of the vanilloid (capsaicin) receptor (TRPV1) in physiology and pathology. Eur. J. Pharmacol. 500 (2004) 351-369
-
(2004)
Eur. J. Pharmacol.
, vol.500
, pp. 351-369
-
-
Nagy, I.1
Sántha, P.2
Jancsó, G.3
Urbán, L.4
-
40
-
-
34347263391
-
Curcumin derivatives inhibit or modulate beta-amyloid precursor protein metabolism
-
Narlawar R., Baumann K., Schubenel R., and Schmidt B. Curcumin derivatives inhibit or modulate beta-amyloid precursor protein metabolism. Neurodegener. Dis. 4 (2007) 88-93
-
(2007)
Neurodegener. Dis.
, vol.4
, pp. 88-93
-
-
Narlawar, R.1
Baumann, K.2
Schubenel, R.3
Schmidt, B.4
-
41
-
-
48149099777
-
Curcumin-derived pyrazoles and isoxazoles: Swiss army knives or blunt tools for Alzheimer's disease?
-
Narlawar R., Pickhardt M., Leuchtenberger S., Baumann K., Krause S., Dyrks T., Weggen S., Mandelkow E., and Schmidt B. Curcumin-derived pyrazoles and isoxazoles: Swiss army knives or blunt tools for Alzheimer's disease?. Chem. Med. Chem. 3 (2008) 165-172
-
(2008)
Chem. Med. Chem.
, vol.3
, pp. 165-172
-
-
Narlawar, R.1
Pickhardt, M.2
Leuchtenberger, S.3
Baumann, K.4
Krause, S.5
Dyrks, T.6
Weggen, S.7
Mandelkow, E.8
Schmidt, B.9
-
42
-
-
1542364225
-
Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro
-
Ono K., Hasegawa K., Naiki H., and Yamada M. Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro. J. Neurosci. Res. 75 (2004) 742-750
-
(2004)
J. Neurosci. Res.
, vol.75
, pp. 742-750
-
-
Ono, K.1
Hasegawa, K.2
Naiki, H.3
Yamada, M.4
-
43
-
-
52049105166
-
Interactions between the amyloid and cholinergic mechanisms in Alzheimer's disease
-
Pákáski M., and Kálmán J. Interactions between the amyloid and cholinergic mechanisms in Alzheimer's disease. Neurochem. Int. 53 (2008) 103-111
-
(2008)
Neurochem. Int.
, vol.53
, pp. 103-111
-
-
Pákáski, M.1
Kálmán, J.2
-
44
-
-
23144463734
-
Alzheimer's disease-associated neurotoxic mechanisms and neuroprotective strategies
-
Pereira C., Agostinho P., Moreira P.I., Cardoso S.M., and Oliveira C.R. Alzheimer's disease-associated neurotoxic mechanisms and neuroprotective strategies. Curr. Drug Targets CNS Neurol. Disord. 4 (2005) 383-403
-
(2005)
Curr. Drug Targets CNS Neurol. Disord.
, vol.4
, pp. 383-403
-
-
Pereira, C.1
Agostinho, P.2
Moreira, P.I.3
Cardoso, S.M.4
Oliveira, C.R.5
-
45
-
-
0034700494
-
Induction of vanilloid receptor channel activity by protein kinase C
-
Premkumar L.S., and Ahern G.P. Induction of vanilloid receptor channel activity by protein kinase C. Nature 408 (2000) 985-990
-
(2000)
Nature
, vol.408
, pp. 985-990
-
-
Premkumar, L.S.1
Ahern, G.P.2
-
46
-
-
0037222109
-
Role of protein kinase C alpha in the regulated secretion of the amyloid precursor protein
-
Racchi M., Mazzucchelli M., Pascale A., Sironi M., and Govoni S. Role of protein kinase C alpha in the regulated secretion of the amyloid precursor protein. Mol. Psychiatry 8 (2003) 209-216
-
(2003)
Mol. Psychiatry
, vol.8
, pp. 209-216
-
-
Racchi, M.1
Mazzucchelli, M.2
Pascale, A.3
Sironi, M.4
Govoni, S.5
-
47
-
-
34547315810
-
Alzheimer's disease: cholesterol, membrane rafts, isoprenoids and statins
-
Reid P.C., Urano Y., Kodama T., and Hamakubo T. Alzheimer's disease: cholesterol, membrane rafts, isoprenoids and statins. J. Cell Mol. Med. 11 (2007) 383-392
-
(2007)
J. Cell Mol. Med.
, vol.11
, pp. 383-392
-
-
Reid, P.C.1
Urano, Y.2
Kodama, T.3
Hamakubo, T.4
-
48
-
-
0033802581
-
Constitutive overactivation of protein kinase C in guinea pig brain increases alpha-secretory APP processing without decreasing beta-amyloid generation
-
Rossner S., Beck M., Stahl T., Mendla K., Schliebs R., and Bigl V. Constitutive overactivation of protein kinase C in guinea pig brain increases alpha-secretory APP processing without decreasing beta-amyloid generation. Eur. J. Neurosci. 12 (2000) 3191-3200
-
(2000)
Eur. J. Neurosci.
, vol.12
, pp. 3191-3200
-
-
Rossner, S.1
Beck, M.2
Stahl, T.3
Mendla, K.4
Schliebs, R.5
Bigl, V.6
-
50
-
-
0028123071
-
Alzheimer's disease: a central role for amyloid
-
Selkoe D.J. Alzheimer's disease: a central role for amyloid. J. Neuropathol. Exp. Neurol. 53 (1994) 438-447
-
(1994)
J. Neuropathol. Exp. Neurol.
, vol.53
, pp. 438-447
-
-
Selkoe, D.J.1
-
51
-
-
0024005801
-
Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact
-
Shivers B.D., Hilbich C., Multhaup G., Salbaum M., Beyreuther K., and Seeburg P.H. Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact. Eur. Mol. Biol. Organ. J. 7 (1988) 1365-1370
-
(1988)
Eur. Mol. Biol. Organ. J.
, vol.7
, pp. 1365-1370
-
-
Shivers, B.D.1
Hilbich, C.2
Multhaup, G.3
Salbaum, M.4
Beyreuther, K.5
Seeburg, P.H.6
-
52
-
-
48349100916
-
The novel calpain inhibitor A-705253 potently inhibits oligomeric beta-amyloid-induced dynamin 1 and tau cleavage in hippocampal neurons
-
Sinjoanu R.C., Kleinschmidt S., Bitner R.S., Brioni J.D., Moeller A., and Ferreira A. The novel calpain inhibitor A-705253 potently inhibits oligomeric beta-amyloid-induced dynamin 1 and tau cleavage in hippocampal neurons. Neurochem. Int. 53 (2008) 79-88
-
(2008)
Neurochem. Int.
, vol.53
, pp. 79-88
-
-
Sinjoanu, R.C.1
Kleinschmidt, S.2
Bitner, R.S.3
Brioni, J.D.4
Moeller, A.5
Ferreira, A.6
-
53
-
-
0027393439
-
Increased levels of the Kunitz protease inhibitor-containing beta APP mRNAs in rat brain following neurotoxic damage
-
Sola C., Garcia-Ladona F.J., Mengod G., Probst A., Frey P., and Palacios J.M. Increased levels of the Kunitz protease inhibitor-containing beta APP mRNAs in rat brain following neurotoxic damage. Brain Res. Mol. Brain Res. 17 (1993) 41-52
-
(1993)
Brain Res. Mol. Brain Res.
, vol.17
, pp. 41-52
-
-
Sola, C.1
Garcia-Ladona, F.J.2
Mengod, G.3
Probst, A.4
Frey, P.5
Palacios, J.M.6
-
54
-
-
2942754093
-
Spices as beneficial hypolipidemic food adjuncts: a review
-
Srinivasan K., Sambaiah K., and Chandrasekhara N. Spices as beneficial hypolipidemic food adjuncts: a review. Food Rev. Int. 20 (2004) 187-220
-
(2004)
Food Rev. Int.
, vol.20
, pp. 187-220
-
-
Srinivasan, K.1
Sambaiah, K.2
Chandrasekhara, N.3
-
55
-
-
0027347295
-
Mechanisms and therapeutic potential of vanilloids (capsaicin-like molecules)
-
Szallasi A., and Blumberg P.M. Mechanisms and therapeutic potential of vanilloids (capsaicin-like molecules). Adv. Pharmacol. 24 (1993) 123-155
-
(1993)
Adv. Pharmacol.
, vol.24
, pp. 123-155
-
-
Szallasi, A.1
Blumberg, P.M.2
-
56
-
-
0033595706
-
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar R., Bennett B.D., Babu-Khan S., Kahn S., Mendiaz E.A., Denis P., Teplow D.B., Ross S., Amarante P., Loeloff R., Luo Y., Fisher S., Fuller J., Edenson S., Lile J., Jarosinski M.A., Biere A.L., Curran E., Burgess T., Louis J.C., Collins F., Treanor J., Rogers G., and Citron M. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science 286 (1999) 735-741
-
(1999)
Science
, vol.286
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.A.5
Denis, P.6
Teplow, D.B.7
Ross, S.8
Amarante, P.9
Loeloff, R.10
Luo, Y.11
Fisher, S.12
Fuller, J.13
Edenson, S.14
Lile, J.15
Jarosinski, M.A.16
Biere, A.L.17
Curran, E.18
Burgess, T.19
Louis, J.C.20
Collins, F.21
Treanor, J.22
Rogers, G.23
Citron, M.24
more..
-
57
-
-
20044370990
-
Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques and reduces amyloid in vivo
-
Yang F., Lim G.P., Begum A.N., Ubeda O.J., Simmons M.R., Ambegaokar S.S., Chen P.P., Kayed R., Glabe C.G., Frautschy S.A., and Cole G.M. Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques and reduces amyloid in vivo. J. Biol. Chem. 280 (2005) 5892-5901
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 5892-5901
-
-
Yang, F.1
Lim, G.P.2
Begum, A.N.3
Ubeda, O.J.4
Simmons, M.R.5
Ambegaokar, S.S.6
Chen, P.P.7
Kayed, R.8
Glabe, C.G.9
Frautschy, S.A.10
Cole, G.M.11
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