Three structurally homologous isothiocyanates exert "janus" characteristics in human hepg2 cells

Environmental and Molecular Mutagenesis

Volumn 50, Issue 3, 2009, Pages 164-170

  Lamy, Evelyn ^a   Crößmann, Catharina ^a   Saeed, Adal ^a   Schreiner, Peter R ^b   Kotke, Mike ^b   Mersch Sundermann, Volker ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

3 Methylthiopropyl isothiocyanate; 4 Methylthiobutyl sothiocyanate; 5 Methylthiopentyl isothiocyanate; Comet assay; DNA repair; HepG2 cells; Micronucleus test

Indexed keywords

3 METHYLTHIOPROPYL ISOTHIOCYANATE; 5 METHYLTHIOPENTYL ISOTHIOCYANATE; ERUCIN; ISOTHIOCYANIC ACID DERIVATIVE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; MUTAGENIC AGENT;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL PROTECTION; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MICRONUCLEUS TEST; MUTAGENICITY; CELL PROLIFERATION; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; ISOLATION AND PURIFICATION; MICRONUCLEUS; PLANT; REGRESSION ANALYSIS; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANTICARCINOGENIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; COMET ASSAY; DNA DAMAGE; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; ISOTHIOCYANATES; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MICRONUCLEUS TESTS; MOLECULAR STRUCTURE; MUTAGENS; PLANTS, EDIBLE; REGRESSION ANALYSIS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 63049132775     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20470     Document Type: Article

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