A role for nitrergic system in the antidepressant-like effects of chronic lithium treatment in the mouse forced swimming test

Behavioural Brain Research

Volumn 200, Issue 1, 2009, Pages 76-82

  Ghasemi, Mehdi ^a   Sadeghipour, Hamed ^a   Poorheidari, Gholamreza ^b   Dehpour, Ahmad Reza ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b BAQIYATALLAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Chronic lithium; Depression; Forced swimming test; L arginine; Lithium; Nitric oxide (NO); Nitric oxide synthase inhibitor

Indexed keywords

ARGININE; LITHIUM; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE;

ACUTE DRUG ADMINISTRATION; ANIMAL EXPERIMENT; ARTICLE; BLOOD LEVEL; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DOSAGE SCHEDULE COMPARISON; DRUG DOSE COMPARISON; DRUG EFFECT; FORCED SWIMMING TEST; IMMOBILIZATION; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; OPEN FIELD BEHAVIOR; PRIORITY JOURNAL; TREATMENT DURATION;

ANALYSIS OF VARIANCE; ANIMALS; ANTIMANIC AGENTS; ARGININE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EXPLORATORY BEHAVIOR; FREEZING REACTION, CATALEPTIC; LITHIUM CHLORIDE; MALE; MICE; MICE, INBRED STRAINS; MOTOR ACTIVITY; NG-NITROARGININE METHYL ESTER; NITRATES; NITRIC OXIDE; NITRITES; SWIMMING;

EID: 62949160276     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2008.12.032     Document Type: Article

References (70)

1. Anai H., Ueta Y., Serino R., Nomura M., Nakashima Y., and Yamashita H. Activation of hypothalamic neuronal nitric oxide synthase in lithium-induced diabetes insipidus rats. Psychoneuroendocrinology 26 (2001) 1009-1020
2. Belmaker R.H. Bipolar disorder. N Engl J Med 351 (2004) 476-486
3. Berridge M.J., and Irvine R.F. Inositol phosphates and cell signalling. Nature 341 (1989) 197-205
4. Borsini F. Role of the serotonergic system in the forced swimming test. Neurosci Biobehav Rev 19 (1995) 377-395
5. Bourin M., and Prica C. The role of mood stabilisers in the treatment of the depressive facet of bipolar disorders. Neurosci Biobehav Rev 31 (2007) 963-975
6. Coryell W., Endicott J., and Keller M.B. Rapidly cycling affective disorder: demographics, diagnosis, family history, and course. Arch Gen Psychiatry 49 (1992) 126-131
7. Cryan J.F., Markou A., and Lucki I. Assessing antidepressant activity in rodents: recent developments and future needs. Trends Pharmacol Sci 23 (2007) 238-245
8. da Silva G.D., Matteussi A.S., dos Santos A.R., Calixto J.B., and Rodrigues A.L. Evidence for dual effects of nitric oxide in the forced swimming test and in the tail suspension test in mice. Neuroreport 11 (2000) 3699-3702
9. Dehpour A.R., Sadr S.S., Nouroddini M., Shadan F., Nourozi A., Farahani A., et al. Comparison of simultaneous administration of lithium with L-NAME or L-arginine on morphine withdrawal syndrome in mice. Hum Psychopharmacol Clin Exp 15 (2000) 87-93
10. Drummond A.H., Joels L.A., and Hughes P.J. The interaction of lithium ions with inositol lipid signalling systems. Biochem Soc Trans 15 (1987) 32-35
11. Faria M.S., and Teixeira N.A. Reversal of learned helplessness by chronic lithium treatment at a prophylactic level. Braz J Med Biol Res 26 (1993) 1201-1212
12. Ghasemi M., Karimollah A., and Dehpour A.R. Nitric oxide involvement in the effect of acute lithium administration on the nonadrenergic noncholinergic-mediated relaxation of rat gastric fundus. Nitric Oxide 17 (2007) 152-159
13. Ghasemi M., Sadeghipour H., Mosleh A., Sadeghipour H.R., Mani A.R., and Dehpour A.R. Nitric oxide involvement in the antidepressant-like effects of acute lithium administration in the mouse forced swimming test. Eur Neuropsychopharmacol 18 (2008) 323-332
14. Gould T.D., Chen G., and Manji H.K. In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3. Neuropsychopharmacology 29 (2004) 32-38
15. Gould T.D., Gray N.A., and Manji H.K. Effects of a glycogen synthase kinase-3 inhibitor, lithium, in adenomatous polyposis coli mutant mice. Pharmacol Res 48 (2003) 49-53
16. Gould T.D., O'Donnell K.C., Dow E.R., Du J., Chen G., and Manji H.K. Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test. Neuropharmacology 54 (2008) 577-587
17. Greil W., and Kleindienst N. Lithium in the long-term treatment of bipolar disorders. Eur Arch Psychiatry Clin Neurosci 253 (2003) 120-125
18. Harkin A., Connor T.J., Burns M.P., and Kelly J.P. Nitric oxide synthase inhibitors augment the effects of serotonin re-uptake inhibitors in the forced swimming test. Eur Neuropsychopharmacol 14 (2004) 274-281
19. Harkin A.J., Bruce K.H., Craft B., and Paul I.A. Nitric oxide synthase inhibitors have antidepressant-like properties in mice. 1. Acute treatments are active in the forced swim test. Eur J Pharmacol 372 (1999) 207-213
20. Harvey B., Carstens M., and Taljaard J. Absence of an effect of the lithium-induced increase in cyclic GMP on the cyclic GMP-stimulated phosphodiesterase (PDE II). Evidence for cyclic AMP-specific hydrolysis. Neurochem Res 18 (1993) 1095-10100
21. Harvey B.H., Carstens M.E., and Taljaard J.J. Evidence that lithium induces a glutamatergic: nitric oxide-mediated response in rat brain. Neurochem Res 19 (1994) 469-474
22. Hashimoto R., Hough C., Nakazawa T., Yamamoto T., and Chuang D.M. Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation. J Neurochem 80 (2002) 589-597
23. Hashioka S., Klegeris A., Monji A., Kato T., Sawada M., McGeer P.L., et al. Antidepressants inhibit interferon-gamma-induced microglial production of IL-6 and nitric oxide. Exp Neurol 206 (2007) 33-42
24. Heninger G.R., Charney D.S., and Sternberg D.E. Lithium carbonate augmentation of antidepressant treatment: an effective prescription for treatment-refractory depression. Arch Gen Psychiatry 40 (1983) 1335-1342
25. Inan S.Y., Yalcin I., and Aksu F. Dual effects of nitric oxide in the mouse forced swimming test: possible contribution of nitric oxide-mediated serotonin release and potassium channel modulation. Pharmacol Biochem Behav 77 (2004) 457-464
26. Jefferys D., and Funder J. Nitric oxide modulates retention of immobility in the forced swimming test in rats. Eur J Pharmacol 295 (1996) 131-135
27. Jope R.S. Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes. Trends Pharmacol Sci 24 (2003) 441-443
28. Jope R.S., and Williams M.B. Lithium and brain signal transduction systems. Biochem Pharmacol 47 (1994) 429-441
29. Karatinos J., Rosse R.B., and Deutsch S.I. The nitric oxide pathway: potential implications for treatment of neuropsychiatric disorders. Clin Neuropharmacol 18 (1995) 482-499
30. Karimollah A.R., Ghasemi M., Ghahremani M.H., and Dehpour AR. Inhibition by lithium of the nitrergic relaxation of rat anococcygeus muscle. Nitric Oxide 20 (2009) 31-38
31. Kaster M.P., Ferreira P.K., Santos A.R.S., and Rodrigues A.L.S. Effects of potassium channel inhibitors in the forced swimming test: possible involvement of L-arginine-nitric oxide-soluble guanylate cyclase pathway. Behav Brain Res 165 (2005) 204-209
32. Katona C.L. Lithium augmentation in refractory depression. Psychiatric Dev 6 (1988) 153-171
33. Khan M.C., Wickham E.A., and Reed J.V. Lithium versus placebo in acute depression: a clinical trial. Int Clin Psychopharmacol 2 (1987) 47-54
34. Klein P.S., and Melton D.A. A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci U S A 93 (1996) 8455-8459
35. Kleindienst N., and Greil W. Lithium in the long-term treatment of bipolar disorders. Eur Arch Psych Clin Neurosci 253 (2003) 120-125
36. Ma J., and Zhang G.Y. Lithium reduced N-methyl-D-aspartate receptor subunit 2A tyrosine phosphorylation and its interactions with Src and Fyn mediated by PSD-95 in rat hippocampus following cerebral ischemia. Neurosci Lett 348 (2003) 185-189
37. Ma J., Zhang G.Y., Liu Y., Yan J.Z., and Hao Z.B. Lithium suppressed Tyr-402 phosphorylation of proline-rich tyrosine kinase (Pyk2) and interactions of Pyk2 and PSD-95 with NR2A in rat hippocampus following cerebral ischemia. Neurosci Res 49 (2004) 357-362
38. Maj J., Rogoz Z., and Skuza G. The effects of combined treatment with MK-801 and antidepressant drugs in the forced swimming test in rats. Pol J Pharmacol Pharm 44 (1992) 217-226
39. Maruta S., Suzuki E., Yokoyama M., Sato T., Inada K., Watanabe S., et al. Effects of intraperitoneally injected lithium, imipramine and diazepam on nitrate levels in rat amygdala. Psych Clin Neurosci 59 (2005) 358-361
40. Mendels J., Secunda S.K., and Dyson W.L. A controlled study of the antidepressant effect of lithium carbonate. Arch Gen Psychiatry 26 (1972) 154-157
41. Miranda K.M., Espey M.G., and Wink D.A. A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite. Nitric Oxide 5 (2001) 62-71
42. Mutlu O., Ulak G., Laugeray A., and Belzung C. Effects of neuronal and inducible NOS inhibitor 1-[2-(trifluoromethyl) phenyl] imidazole (TRIM) in unpredictable chronic mild stress procedure in mice. Pharmacol Biochem Behav (2008) [Epub ahead of print]
43. Nahorski S.R., Ragan C.I., and Challiss R.A. Lithium and the phosphoinositide cycle: an example of uncompetitive inhibition and its pharmacological consequences. Trends Pharmacol Sci 12 (1991) 297-303
44. Nixon M.K., Hascoet M., Bourin M., and Colombel M.C. Additive effects of lithium and antidepressants in the forced swimming test: further evidence for involvement of the serotoninergic system. Psychopharmacology (Berl) 115 (1994) 59-64
45. Nonaka S., Hough C.J., and Chuang D.M. Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx. Proc Natl Acad Sci U S A 95 (1998) 2642-2647
46. Nonaka S., Katsube N., and Chuang D.M. Lithium protects rat cerebellar granule cells against apoptosis induced by anticonvulsants, phenytoin and carbamazepine. J Pharmacol Exp Ther 286 (1998) 539-547
47. O'Brien W.T., Harper A.D., Jove F., Woodgett J.R., Maretto S., Piccolo S., et al. Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium. J Neurosci 24 (2004) 6791-6798
48. Paoletti A.M., Piccirilli S., Costa N., Rotiroti D., Bagetta G., and Nisticò G. Systemic administration of N omega-nitro-L-arginine methyl ester and indomethacin reduces the elevation of brain PGE2 content and prevents seizures and hippocampal damage evoked by LiCl and tacrine in rat. Exp Neurol 149 (1998) 349-355
49. Paul I.A., and Skolnick P. Glutamate and depression: clinical and preclinical studies. Ann N Y Acad Sci 1003 (2003) 250-272
50. Porsolt R.D., Bertin A., and Jalfre M. Behavioral despair in mice: a primary screening test for antidepressants. Arch Int Pharmacodyn Ther 229 (1977) 327-336
51. Price L.H., and Heninger G.R. Lithium in the treatment of mood disorders. N Engl J Med 331 (1994) 591-598
52. Redrobe J.P., and Bourin M. The effect of lithium administration in animal models of depression: a short review. Fundam Clin Pharmacol 13 (1999) 293-299
53. Sadeghipour H., Dehghani M., Ghasemi M., Riazi K., Asadi S., Ebrahimi F., et al. The nonadrenergic noncholinergic-mediated relaxation of corpus cavernosum was impaired in chronic lithium-treated rats: improvement with l-arginine. Eur J Pharmacol 586 (2008) 300-305
54. Sadeghipour H., Ghasemi M., Ebrahimi F., and Dehpour A.R. Effect of lithium on endothelium-dependent and neurogenic relaxation of rat corpus cavernosum: role of nitric oxide pathway. Nitric Oxide 16 (2007) 54-63
55. Sadeghipour H., Ghasemi M., Nobakht M., Ebrahimi F., and Dehpour A.R. Effect of chronic lithium administration on endothelium-dependent relaxation of rat corpus cavernosum: the role of nitric oxide and cyclooxygenase pathways. BJU Int 99 (2007) 177-182
56. Savas H.A., Gergerlioglu H.S., Armutcu F., Herken H., Yilmaz H.R., Kocoglu E., et al. Elevated serum nitric oxide and superoxide dismutase in euthymic bipolar patients: impact of past episodes. World J Biol Psychiatry 7 (2006) 51-55
57. Savas H.A., Herken H., Yurekli M., Uz E., Tutkun H., Zoroglu S.S., et al. Possible pathophysiological role of nitric oxide and adrenomedullin in bipolar affective disorder. Neuropsychobiology 45 (2002) 57-61
58. Selek S., Savas H.A., Gergerlioglu H.S., Bulbul F., Uz E., and Yumru M. The course of nitric oxide and superoxide dismutase during treatment of bipolar depressive episode. J Affect Disord 107 (2008) 89-94
59. Shaldubina A., Stahl Z., Furszpan M., Regenold W.T., Shapiro J., Belmaker R.H., et al. Inositol deficiency diet and lithium effects. Bipolar Disord 8 (2006) 152-159
60. Skolnick P., Miller R., Young A., Boje K., and Trullas R. Chronic treatment with 1-aminocyclopropanecarboxylic acid desensitizes behavioral responses to compounds acting at the N-methyl-D-aspartate receptor complex. Psychopharmacology (Berl) 107 (1992) 489-496
61. Soares J.C., and Gershon S. The lithium ion: a foundation for psychopharmacological specificity. Neuropsychopharmacology 19 (1998) 167-182
62. Suzuki E., Yagi G., Nakaki T., Kanba S., and Asai M. Elevated plasma nitrate levels in depressive states. J Affect Disord 63 (2001) 221-224
63. Teixeira N.A., Pereira D.G., and Hermini A.H. Chronic but not acute Li+ treatment prevents behavioral depression in rats. Braz J Med Biol Res 28 (1995) 1003-1007
64. Trullas R., and Skolnick P. Functional antagonists at the NMDA receptor complex exhibit antidepressant actions. Eur J Pharmacol 185 (1990) 1-10
65. Ulak G., Mutlu O., Akar F.Y., Komsuoǧlu F.I., Tanyeri P., and Erden B.F. Neuronal NOS inhibitor 1-(2-trifluoromethylphenyl)-imidazole augment the effects of antidepressants acting via serotonergic system in the forced swimming test in rats. Phamacol Biocem Behav 90 (2008) 563-568
66. Watanabe S., Ishino H., and Otsuki S. Double-blind comparison of lithium carbonate and imipramine in treatment of depression. Arch Gen Psychiatry 32 (1975) 659-668
67. Weerasinghe G.R., Rapoport S.I., and Bosetti F. The effect of chronic lithium on arachidonic acid release and metabolism in rat brain does not involve secretory phospholipase A2 or lipoxygenase/cytochrome P450 pathways. Brain Res Bull 63 (2004) 485-489
68. Wegener G., Bandpey Z., Heiberg I.L., Mørk A., and Rosenberg R. Increased extracellular serotonin level in rat hippocampus induced by chronic citalopram is augmented by subchronic lithium: neurochemical and behavioural studies in the rat. Psychopharmacology 166 (2003) 188-194
69. Worrall E.P., Moody J.P., Peet M., Dick P., Smith A., Chambers C., et al. Controlled studies of the acute antidepressant effects of lithium. Br J Pharmacol 135 (1979) 255-262
70. Yildiz F., Erden B.F., Ulak G., Utkan T., and Gacar N. Antidepressant-like effect of 7-nitroindazole in the forced swimming test in rats. Psychopharmacology 149 (2000) 41-44