-
1
-
-
27844541328
-
Modeling T cell antigen discrimination based on feedback control of digital ERK responses
-
Altan-Bonnet, G., and R. N. Germain. 2005. Modeling T cell antigen discrimination based on feedback control of digital ERK responses. PLoS Biol. 3:e356.
-
(2005)
PLoS Biol
, vol.3
-
-
Altan-Bonnet, G.1
Germain, R.N.2
-
2
-
-
0034062812
-
H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway
-
Apolloni, A., I. A. Prior, M. Lindsay, R. G. Parton, and J. F. Hancock. 2000. H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway. Mol. Cell. Biol. 20:2475-2487.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 2475-2487
-
-
Apolloni, A.1
Prior, I.A.2
Lindsay, M.3
Parton, R.G.4
Hancock, J.F.5
-
5
-
-
4644359297
-
Differential requirements for Vav proteins in DAP10- and ITAM-mediated NK cell cytotoxicity
-
Cella, M., K. Fujikawa, I. Tassi, S. Kim, K. Latinis, S. Nishi, W. Yokoyama, M. Colonna, and W. Swat. 2004. Differential requirements for Vav proteins in DAP10- and ITAM-mediated NK cell cytotoxicity. J. Exp. Med. 200:817-823.
-
(2004)
J. Exp. Med
, vol.200
, pp. 817-823
-
-
Cella, M.1
Fujikawa, K.2
Tassi, I.3
Kim, S.4
Latinis, K.5
Nishi, S.6
Yokoyama, W.7
Colonna, M.8
Swat, W.9
-
6
-
-
33745882375
-
CD28-stimulated ERK2 phosphorylation is required for polarization of the microtubule organizing center and granules in YTS NK cells
-
Chen, X., D. S. Allan, K. Krzewski, B. Ge, H. Kopcow, and J. L. Strominger. 2006. CD28-stimulated ERK2 phosphorylation is required for polarization of the microtubule organizing center and granules in YTS NK cells. Proc. Natl. Acad. Sci. USA 103:10346-10351.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 10346-10351
-
-
Chen, X.1
Allan, D.S.2
Krzewski, K.3
Ge, B.4
Kopcow, H.5
Strominger, J.L.6
-
7
-
-
34547541753
-
Many NK cell receptors activate ERK2 and JNK1 to trigger microtubule organizing center and granule polarization and cytotoxicity
-
Chen, X., P. P. Trivedi, B. Ge, K. Krzewski, and J. L. Strominger. 2007. Many NK cell receptors activate ERK2 and JNK1 to trigger microtubule organizing center and granule polarization and cytotoxicity. Proc. Natl. Acad. Sci. USA 104:6329-6334.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 6329-6334
-
-
Chen, X.1
Trivedi, P.P.2
Ge, B.3
Krzewski, K.4
Strominger, J.L.5
-
8
-
-
0033538559
-
Endomembrane trafficking of ras: The CAAX motif targets proteins to the ER and Golgi
-
Choy, E., V. K. Chiu, J. Silletti, M. Feoktistov, T. Morimoto, D. Michaelson, I. E. Ivanov, and M. R. Philips. 1999. Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi. Cell 98:69-80.
-
(1999)
Cell
, vol.98
, pp. 69-80
-
-
Choy, E.1
Chiu, V.K.2
Silletti, J.3
Feoktistov, M.4
Morimoto, T.5
Michaelson, D.6
Ivanov, I.E.7
Philips, M.R.8
-
9
-
-
33645520353
-
A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila
-
Douziech, M., M. Sahmi, G. Laberge, and M. Therrien. 2006. A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila. Genes Dev. 20:807-819.
-
(2006)
Genes Dev
, vol.20
, pp. 807-819
-
-
Douziech, M.1
Sahmi, M.2
Laberge, G.3
Therrien, M.4
-
10
-
-
33750322263
-
The MAPK scaffold kinase suppressor of Ras is involved in ERK activation by stress and proinflammatory cytokines and induction of arthritis
-
Fusello, A. M., L. Mandik-Nayak, F. Shih, R. E. Lewis, P. M. Allen, and A. S. Shaw. 2006. The MAPK scaffold kinase suppressor of Ras is involved in ERK activation by stress and proinflammatory cytokines and induction of arthritis. J. Immunol. 177:6152-6158.
-
(2006)
J. Immunol
, vol.177
, pp. 6152-6158
-
-
Fusello, A.M.1
Mandik-Nayak, L.2
Shih, F.3
Lewis, R.E.4
Allen, P.M.5
Shaw, A.S.6
-
11
-
-
0035991881
-
Expression of kinase suppressor of Ras in the normal adult and embryonic mouse
-
Giblett, S. M., D. J. Lloyd, Y. Light, R. Marais, and C. A. Pritchard. 2002. Expression of kinase suppressor of Ras in the normal adult and embryonic mouse. Cell Growth Differ. 13:307-313.
-
(2002)
Cell Growth Differ
, vol.13
, pp. 307-313
-
-
Giblett, S.M.1
Lloyd, D.J.2
Light, Y.3
Marais, R.4
Pritchard, C.A.5
-
12
-
-
0036910991
-
NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation
-
Gilfillan, S., E. L. Ho, M. Cella, W. M. Yokoyama, and M. Colonna. 2002. NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation. Nat. Immunol. 3:1150-1155.
-
(2002)
Nat. Immunol
, vol.3
, pp. 1150-1155
-
-
Gilfillan, S.1
Ho, E.L.2
Cella, M.3
Yokoyama, W.M.4
Colonna, M.5
-
13
-
-
37549019661
-
Phosphatidylinositol 3-kinase activation is required to form the NKG2D immunological synapse
-
Giurisato, E., M. Cella, T. Takai, T. Kurosaki, Y. Feng, G. D. Longmore, M. Colonna, and A. S. Shaw. 2007. Phosphatidylinositol 3-kinase activation is required to form the NKG2D immunological synapse. Mol. Cell. Biol. 27:8583-8599.
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 8583-8599
-
-
Giurisato, E.1
Cella, M.2
Takai, T.3
Kurosaki, T.4
Feng, Y.5
Longmore, G.D.6
Colonna, M.7
Shaw, A.S.8
-
14
-
-
27144515650
-
H-Ras dynamically interacts with recycling endosomes in CHO-K1 cells: Involvement of Rab5 and Rab11 in the trafficking of H-Ras to this pericentriolar endocytic compartment
-
Gomez, G. A., and J. L. Daniotti. 2005. H-Ras dynamically interacts with recycling endosomes in CHO-K1 cells: involvement of Rab5 and Rab11 in the trafficking of H-Ras to this pericentriolar endocytic compartment. J. Biol. Chem. 280:34997-35010.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 34997-35010
-
-
Gomez, G.A.1
Daniotti, J.L.2
-
15
-
-
0028281045
-
Characterization of a human cell line (NK-92) with phenotypical and functional characteristics of activated natural killer cells
-
Gong, J. H., G. Maki, and H. G. Klingemann. 1994. Characterization of a human cell line (NK-92) with phenotypical and functional characteristics of activated natural killer cells. Leukemia 8:652-658.
-
(1994)
Leukemia
, vol.8
, pp. 652-658
-
-
Gong, J.H.1
Maki, G.2
Klingemann, H.G.3
-
16
-
-
18844364205
-
Subcellular localization determines MAP kinase signal output
-
Harding, A., T. Tian, E. Westbury, E. Frische, and J. F. Hancock. 2005. Subcellular localization determines MAP kinase signal output. Curr. Biol. 15:869-873.
-
(2005)
Curr. Biol
, vol.15
, pp. 869-873
-
-
Harding, A.1
Tian, T.2
Westbury, E.3
Frische, E.4
Hancock, J.F.5
-
17
-
-
0034330547
-
Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells
-
Jiang, K., B. Zhong, D. L. Gilvary, B. C. Corliss, E. Hong-Geller, S. Wei, and J. Y. Djeu. 2000. Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells. Nat. Immunol. 1:419-425.
-
(2000)
Nat. Immunol
, vol.1
, pp. 419-425
-
-
Jiang, K.1
Zhong, B.2
Gilvary, D.L.3
Corliss, B.C.4
Hong-Geller, E.5
Wei, S.6
Djeu, J.Y.7
-
18
-
-
27644575157
-
Coordinating ERK/MAPK signalling through scaffolds and inhibitors
-
Kolch, W. 2005. Coordinating ERK/MAPK signalling through scaffolds and inhibitors. Nat. Rev. Mol. Cell Biol. 6:827-837.
-
(2005)
Nat. Rev. Mol. Cell Biol
, vol.6
, pp. 827-837
-
-
Kolch, W.1
-
19
-
-
0029588204
-
The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans
-
Kornfeld, K., D. B. Hom, and H. R. Horvitz. 1995. The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans. Cell 83:903-913.
-
(1995)
Cell
, vol.83
, pp. 903-913
-
-
Kornfeld, K.1
Hom, D.B.2
Horvitz, H.R.3
-
20
-
-
23844533650
-
The molecular scaffold kinase suppressor of Ras 1 (KSR1) regulates adipogenesis
-
Kortum, R. L., D. L. Costanzo, J. Haferbier, S. J. Schreiner, G. L. Razidlo, M. H. Wu, D. J. Volle, T. Mori, H. Sakaue, N. V. Chaika, O. V. Chaika, and R. E. Lewis. 2005. The molecular scaffold kinase suppressor of Ras 1 (KSR1) regulates adipogenesis. Mol. Cell. Biol. 25:7592-7604.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 7592-7604
-
-
Kortum, R.L.1
Costanzo, D.L.2
Haferbier, J.3
Schreiner, S.J.4
Razidlo, G.L.5
Wu, M.H.6
Volle, D.J.7
Mori, T.8
Sakaue, H.9
Chaika, N.V.10
Chaika, O.V.11
Lewis, R.E.12
-
21
-
-
2942531229
-
The molecular scaffold KSR1 regulates the proliferative and oncogenic potential of cells
-
Kortum, R. L., and R. E. Lewis. 2004. The molecular scaffold KSR1 regulates the proliferative and oncogenic potential of cells. Mol. Cell. Biol. 24:4407-4416.
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 4407-4416
-
-
Kortum, R.L.1
Lewis, R.E.2
-
22
-
-
34548059483
-
Scaffold proteins confer diverse regulatory properties to protein kinase cascades
-
Locasale, J. W., A. S. Shaw, and A. K. Chakraborty. 2007. Scaffold proteins confer diverse regulatory properties to protein kinase cascades. Proc. Natl. Acad. Sci. USA 104:13307-13312.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 13307-13312
-
-
Locasale, J.W.1
Shaw, A.S.2
Chakraborty, A.K.3
-
23
-
-
0035654722
-
Role of calcium influx in cytotoxic T lymphocyte lytic granule exocytosis during target cell killing
-
Lyubchenko, T. A., G. A. Wurth, and A. Zweifach. 2001. Role of calcium influx in cytotoxic T lymphocyte lytic granule exocytosis during target cell killing. Immunity 15:847-859.
-
(2001)
Immunity
, vol.15
, pp. 847-859
-
-
Lyubchenko, T.A.1
Wurth, G.A.2
Zweifach, A.3
-
24
-
-
0030724987
-
KSR stimulates Raf-1 activity in a kinase-independent manner
-
Michaud, N. R., M. Therrien, A. Cacace, L. C. Edsall, S. Spiegel, G. M. Rubin, and D. K. Morrison. 1997. KSR stimulates Raf-1 activity in a kinase-independent manner. Proc. Natl. Acad. Sci. USA 94:12792-12796.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 12792-12796
-
-
Michaud, N.R.1
Therrien, M.2
Cacace, A.3
Edsall, L.C.4
Spiegel, S.5
Rubin, G.M.6
Morrison, D.K.7
-
25
-
-
34447579251
-
The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2
-
Mor, A., G. Campi, G. Du, Y. Zheng, D. A. Foster, M. L. Dustin, and M. R. Philips. 2007. The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2. Nat. Cell Biol. 9:713-719.
-
(2007)
Nat. Cell Biol
, vol.9
, pp. 713-719
-
-
Mor, A.1
Campi, G.2
Du, G.3
Zheng, Y.4
Foster, D.A.5
Dustin, M.L.6
Philips, M.R.7
-
26
-
-
33644864788
-
Compartmentalized Ras/MAPK signaling
-
Mor, A., and M. R. Philips. 2006. Compartmentalized Ras/MAPK signaling. Annu. Rev. Immunol. 24:771-800.
-
(2006)
Annu. Rev. Immunol
, vol.24
, pp. 771-800
-
-
Mor, A.1
Philips, M.R.2
-
27
-
-
0035018017
-
KSR: A MAPK scaffold of the Ras pathway? J
-
Morrison, D. K. 2001. KSR: a MAPK scaffold of the Ras pathway? J. Cell Sci. 114:1609-1612.
-
(2001)
Cell Sci
, vol.114
, pp. 1609-1612
-
-
Morrison, D.K.1
-
28
-
-
0344393408
-
Regulation of MAP kinase signaling modules by scaffold proteins in mammals
-
Morrison, D. K., and R. J. Davis. 2003. Regulation of MAP kinase signaling modules by scaffold proteins in mammals. Annu. Rev. Cell Dev. Biol. 19:91-118.
-
(2003)
Annu. Rev. Cell Dev. Biol
, vol.19
, pp. 91-118
-
-
Morrison, D.K.1
Davis, R.J.2
-
29
-
-
0343517174
-
Identification of B-KSR1, a novel brain-specific isoform of KSR1 that functions in neuronal signaling
-
Muller, J., A. M. Cacace, W. E. Lyons, C. B. McGill, and D. K. Morrison. 2000. Identification of B-KSR1, a novel brain-specific isoform of KSR1 that functions in neuronal signaling. Mol. Cell. Biol. 20:5529-5539.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 5529-5539
-
-
Muller, J.1
Cacace, A.M.2
Lyons, W.E.3
McGill, C.B.4
Morrison, D.K.5
-
30
-
-
0036239642
-
Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo
-
Nguyen, A., W. R. Burack, J. L. Stock, R. Kortum, O. V. Chaika, M. Afkarian, W. J. Muller, K. M. Murphy, D. K. Morrison, R. E. Lewis, J. McNeish, and A. S. Shaw. 2002. Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo. Mol. Cell. Biol. 22:3035-3045.
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 3035-3045
-
-
Nguyen, A.1
Burack, W.R.2
Stock, J.L.3
Kortum, R.4
Chaika, O.V.5
Afkarian, M.6
Muller, W.J.7
Murphy, K.M.8
Morrison, D.K.9
Lewis, R.E.10
McNeish, J.11
Shaw, A.S.12
-
31
-
-
0033199236
-
STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells
-
Nosaka, T., T. Kawashima, K. Misawa, K. Ikuta, A. L. Mui, and T. Kitamura. 1999. STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells. EMBO J. 18:4754-4765.
-
(1999)
EMBO J
, vol.18
, pp. 4754-4765
-
-
Nosaka, T.1
Kawashima, T.2
Misawa, K.3
Ikuta, K.4
Mui, A.L.5
Kitamura, T.6
-
32
-
-
0037022533
-
-
Ohmachi, M., C. E. Rocheleau, D. Church, E. Lambie, T. Schedl, and M. V. Sundaram. 2002. C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation. Curr. Biol. 12:427-433.
-
Ohmachi, M., C. E. Rocheleau, D. Church, E. Lambie, T. Schedl, and M. V. Sundaram. 2002. C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation. Curr. Biol. 12:427-433.
-
-
-
-
33
-
-
50249184550
-
-
Orange, J. S. 18 August 2008, posting date. Formation and function of the lytic NK-cell immunological synapse. Nat. Rev. Immunol. [Epub ahead of print.] doi:10.1038/nri2381.
-
Orange, J. S. 18 August 2008, posting date. Formation and function of the lytic NK-cell immunological synapse. Nat. Rev. Immunol. [Epub ahead of print.] doi:10.1038/nri2381.
-
-
-
-
34
-
-
0345060886
-
The mature activating natural killer cell immunologic synapse is formed in distinct stages
-
Orange, J. S., K. E. Harris, M. M. Andzelm, M. M. Valter, R. S. Geha, and J. L. Strominger. 2003. The mature activating natural killer cell immunologic synapse is formed in distinct stages. Proc. Natl. Acad. Sci. USA 100:14151-14156.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 14151-14156
-
-
Orange, J.S.1
Harris, K.E.2
Andzelm, M.M.3
Valter, M.M.4
Geha, R.S.5
Strominger, J.L.6
-
35
-
-
0042178312
-
Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites
-
Ory, S., M. Zhou, T. P. Conrads, T. D. Veenstra, and D. K. Morrison. 2003. Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites. Curr. Biol. 13:1356-1364.
-
(2003)
Curr. Biol
, vol.13
, pp. 1356-1364
-
-
Ory, S.1
Zhou, M.2
Conrads, T.P.3
Veenstra, T.D.4
Morrison, D.K.5
-
36
-
-
1842609782
-
Ras activation in Jurkat T cells following low-grade stimulation of the T-cell receptor is specific to N-Ras and occurs only on the Golgi apparatus
-
Perez de Castro, I., T. G. Bivona, M. R. Philips, and A. Pellicer. 2004. Ras activation in Jurkat T cells following low-grade stimulation of the T-cell receptor is specific to N-Ras and occurs only on the Golgi apparatus. Mol. Cell. Biol. 24:3485-3496.
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 3485-3496
-
-
Perez de Castro, I.1
Bivona, T.G.2
Philips, M.R.3
Pellicer, A.4
-
37
-
-
29144528806
-
Ras signaling from plasma membrane and endomembrane microdomains
-
Plowman, S. J., and J. F. Hancock. 2005. Ras signaling from plasma membrane and endomembrane microdomains. Biochim. Biophys. Acta 1746:274-283.
-
(2005)
Biochim. Biophys. Acta
, vol.1746
, pp. 274-283
-
-
Plowman, S.J.1
Hancock, J.F.2
-
38
-
-
0034998678
-
Compartmentalization of Ras proteins
-
Prior, I. A., and J. F. Hancock. 2001. Compartmentalization of Ras proteins. J. Cell Sci. 114:1603-1608.
-
(2001)
J. Cell Sci
, vol.114
, pp. 1603-1608
-
-
Prior, I.A.1
Hancock, J.F.2
-
39
-
-
0037062775
-
KSR - a regulator and scaffold protein of the MAPK pathway
-
Raabe, T., and U. R. Rapp. 2002. KSR - a regulator and scaffold protein of the MAPK pathway. Sci. STKE 2002:PE28.
-
(2002)
Sci. STKE
, vol.2002
-
-
Raabe, T.1
Rapp, U.R.2
-
40
-
-
9144244353
-
Phosphorylation regulates KSR1 stability, ERK activation, and cell proliferation
-
Razidlo, G. L., R. L. Kortum, J. L. Haferbier, and R. E. Lewis. 2004. Phosphorylation regulates KSR1 stability, ERK activation, and cell proliferation. J. Biol. Chem. 279:47808-47814.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 47808-47814
-
-
Razidlo, G.L.1
Kortum, R.L.2
Haferbier, J.L.3
Lewis, R.E.4
-
41
-
-
43149088532
-
Intercellular transfer of oncogenic H-Ras at the immunological synapse
-
Rechavi, O., I. Goldstein, H. Vernitsky, B. Rotblat, and Y. Kloog. 2007. Intercellular transfer of oncogenic H-Ras at the immunological synapse. PLoS ONE 2:e1204.
-
(2007)
PLoS ONE
, vol.2
-
-
Rechavi, O.1
Goldstein, I.2
Vernitsky, H.3
Rotblat, B.4
Kloog, Y.5
-
42
-
-
29144503720
-
A role for phosphatidylinositol 3-kinase in TCR-stimulated ERK activation leading to paxillin phosphorylation and CTL degranulation
-
Robertson, L. K., L. R. Mireau, and H. L. Ostergaard. 2005. A role for phosphatidylinositol 3-kinase in TCR-stimulated ERK activation leading to paxillin phosphorylation and CTL degranulation. J. Immunol. 175:8138- 8145.
-
(2005)
J. Immunol
, vol.175
, pp. 8138-8145
-
-
Robertson, L.K.1
Mireau, L.R.2
Ostergaard, H.L.3
-
43
-
-
45149109796
-
The Caenorhabditis elegans ekl (enhancer of ksr-1 lethality) genes include putative components of a germline small RNA pathway
-
Rocheleau, C. E., K. Cullison, K. Huang, Y. Bernstein, A. C. Spilker, and M. V. Sundaram. 2008. The Caenorhabditis elegans ekl (enhancer of ksr-1 lethality) genes include putative components of a germline small RNA pathway. Genetics 178:1431-1443.
-
(2008)
Genetics
, vol.178
, pp. 1431-1443
-
-
Rocheleau, C.E.1
Cullison, K.2
Huang, K.3
Bernstein, Y.4
Spilker, A.C.5
Sundaram, M.V.6
-
44
-
-
0037083988
-
KSR is a scaffold required for activation of the ERK/MAPK module
-
Roy, F., G. Laberge, M. Douziech, D. Ferland-McCollough, and M. Therrien. 2002. KSR is a scaffold required for activation of the ERK/MAPK module. Genes Dev. 16:427-438.
-
(2002)
Genes Dev
, vol.16
, pp. 427-438
-
-
Roy, F.1
Laberge, G.2
Douziech, M.3
Ferland-McCollough, D.4
Therrien, M.5
-
45
-
-
33751294581
-
The role of scaffold proteins in MEK/ERK signalling
-
Sacks, D. B. 2006. The role of scaffold proteins in MEK/ERK signalling. Biochem. Soc. Trans. 34:833-836.
-
(2006)
Biochem. Soc. Trans
, vol.34
, pp. 833-836
-
-
Sacks, D.B.1
-
46
-
-
34547204160
-
The MEK/ERK cascade: From signaling specificity to diverse functions
-
Shaul, Y. D., and R. Seger. 2007. The MEK/ERK cascade: from signaling specificity to diverse functions. Biochim. Biophys. Acta 1773:1213-1226.
-
(2007)
Biochim. Biophys. Acta
, vol.1773
, pp. 1213-1226
-
-
Shaul, Y.D.1
Seger, R.2
-
47
-
-
0037338890
-
TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways
-
Stefanova, I., B. Hemmer, M. Vergelli, R. Martin, W. E. Biddison, and R. N. Germain. 2003. TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways. Nat. Immunol. 4:248-254.
-
(2003)
Nat. Immunol
, vol.4
, pp. 248-254
-
-
Stefanova, I.1
Hemmer, B.2
Vergelli, M.3
Martin, R.4
Biddison, W.E.5
Germain, R.N.6
-
48
-
-
0035655587
-
The immunological synapse of CTL contains a secretory domain and membrane bridges
-
Stinchcombe, J. C., G. Bossi, S. Booth, and G. M. Griffiths. 2001. The immunological synapse of CTL contains a secretory domain and membrane bridges. Immunity 15:751-761.
-
(2001)
Immunity
, vol.15
, pp. 751-761
-
-
Stinchcombe, J.C.1
Bossi, G.2
Booth, S.3
Griffiths, G.M.4
-
50
-
-
33749185296
-
Centrosome polarization delivers secretory granules to the immunological synapse
-
Stinchcombe, J. C., E. Majorovits, G. Bossi, S. Fuller, and G. M. Griffiths. 2006. Centrosome polarization delivers secretory granules to the immunological synapse. Nature 443:462-465.
-
(2006)
Nature
, vol.443
, pp. 462-465
-
-
Stinchcombe, J.C.1
Majorovits, E.2
Bossi, G.3
Fuller, S.4
Griffiths, G.M.5
-
51
-
-
0029559183
-
The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction
-
Sundaram, M., and M. Han. 1995. The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction. Cell 83:889-901.
-
(1995)
Cell
, vol.83
, pp. 889-901
-
-
Sundaram, M.1
Han, M.2
-
52
-
-
10144220631
-
A Ras-mediated signal transduction pathway is involved in the control of sex myoblast migration in Caenorhabditis elegans
-
Sundaram, M., J. Yochem, and M. Han. 1996. A Ras-mediated signal transduction pathway is involved in the control of sex myoblast migration in Caenorhabditis elegans. Development 122:2823-2833.
-
(1996)
Development
, vol.122
, pp. 2823-2833
-
-
Sundaram, M.1
Yochem, J.2
Han, M.3
-
53
-
-
0029584327
-
KSR, a novel protein kinase required for RAS signal transduction
-
Therrien, M., H. C. Chang, N. M. Solomon, F. D. Karim, D. A. Wassarman, and G. M. Rubin. 1995. KSR, a novel protein kinase required for RAS signal transduction. Cell 83:879-888.
-
(1995)
Cell
, vol.83
, pp. 879-888
-
-
Therrien, M.1
Chang, H.C.2
Solomon, N.M.3
Karim, F.D.4
Wassarman, D.A.5
Rubin, G.M.6
-
54
-
-
0038731186
-
Delivering the kiss of death
-
Trambas, C. M., and G. M. Griffiths. 2003. Delivering the kiss of death. Nat. Immunol. 4:399-403.
-
(2003)
Nat. Immunol
, vol.4
, pp. 399-403
-
-
Trambas, C.M.1
Griffiths, G.M.2
-
55
-
-
0027421614
-
Phosphorylation of serine 59 of p56lck in activated T cells
-
Watts, J. D., J. S. Sanghera, S. L. Pelech, and R. Aebersold. 1993. Phosphorylation of serine 59 of p56lck in activated T cells. J. Biol. Chem. 268:23275-23282.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 23275-23282
-
-
Watts, J.D.1
Sanghera, J.S.2
Pelech, S.L.3
Aebersold, R.4
-
56
-
-
0032100476
-
Control of lytic function by mitogen-activated protein kinase/extracellular regulatory kinase 2 (ERK2) in a human natural killer cell line: Identification of perforin and granzyme B mobilization by functional ERK2
-
Wei, S., A. M. Gamero, J. H. Liu, A. A. Daulton, N. I. Valkov, J. A. Trapani, A. C. Larner, M. J. Weber, and J. Y. Djeu. 1998. Control of lytic function by mitogen-activated protein kinase/extracellular regulatory kinase 2 (ERK2) in a human natural killer cell line: identification of perforin and granzyme B mobilization by functional ERK2. J. Exp. Med. 187:1753-1765.
-
(1998)
J. Exp. Med
, vol.187
, pp. 1753-1765
-
-
Wei, S.1
Gamero, A.M.2
Liu, J.H.3
Daulton, A.A.4
Valkov, N.I.5
Trapani, J.A.6
Larner, A.C.7
Weber, M.J.8
Djeu, J.Y.9
-
58
-
-
33747092261
-
Altered peptide ligands induce delayed CD8-T cell receptor interaction - a role for CD8 in distinguishing antigen quality
-
Yachi, P. P., J. Ampudia, T. Zal, and N. R. Gascoigne. 2006. Altered peptide ligands induce delayed CD8-T cell receptor interaction - a role for CD8 in distinguishing antigen quality. Immunity 25:203-211.
-
(2006)
Immunity
, vol.25
, pp. 203-211
-
-
Yachi, P.P.1
Ampudia, J.2
Zal, T.3
Gascoigne, N.R.4
-
59
-
-
0031974812
-
Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK
-
Yu, W., W. J. Fantl, G. Harrowe, and L. T. Williams. 1998. Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK. Curr. Biol. 8:56-64.
-
(1998)
Curr. Biol
, vol.8
, pp. 56-64
-
-
Yu, W.1
Fantl, W.J.2
Harrowe, G.3
Williams, L.T.4
-
60
-
-
0036301210
-
Solution structure and functional analysis of the cysteine-rich C1 domain of kinase suppressor of Ras (KSR)
-
Zhou, M., D. A. Horita, D. S. Waugh, R. A. Byrd, and D. K. Morrison. 2002. Solution structure and functional analysis of the cysteine-rich C1 domain of kinase suppressor of Ras (KSR). J. Mol. Biol. 315:435-446.
-
(2002)
J. Mol. Biol
, vol.315
, pp. 435-446
-
-
Zhou, M.1
Horita, D.A.2
Waugh, D.S.3
Byrd, R.A.4
Morrison, D.K.5
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