Cytokine gene polymorphisms across tuberculosis clinical spectrum in Pakistani patients

PLoS ONE

Volumn 4, Issue 3, 2009, Pages

  Ansari, Ambreen ^a   Talat, Najeeha ^a   Jamil, Bushra ^a   Hasan, Zahra ^a   Razzaki, Tashmeem ^b   Dawood, Ghaffar ^c   Hussain, Rabia ^a  

^a AGA KHAN UNIVERSITY   (Pakistan)

^b SINDH INSTITUTE OF UROLOGY AND TRANSPLANTATION   (Pakistan)

^c Masoomeen General Hospital   (Pakistan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; GAMMA INTERFERON; GLYCINE; INTERLEUKIN 10; THREONINE; CYTOKINE;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE SEVERITY; EXTRAPULMONARY TUBERCULOSIS; FEMALE; GENE FREQUENCY; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENOTYPE PHENOTYPE CORRELATION; HUMAN; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; PAKISTAN; PHENOTYPE; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; STRATIFICATION; BLOOD; CASE CONTROL STUDY; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HOSPITALIZATION; TUBERCULOSIS;

CASE-CONTROL STUDIES; CYTOKINES; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-10; PAKISTAN; POLYMORPHISM, GENETIC; SEVERITY OF ILLNESS INDEX; TUBERCULOSIS;

EID: 62849092522     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004778     Document Type: Article

References (41)

1. Akhtar S, Carpenter TE, Rathi SK (2007) A chain binomial model for intrahousehold spread of Mycobacterium tuberculosis in a low socio-economic setting in Pakistan. Epidemiol Infect 135: 27-33.
2. Dhingra VK, Rajpal S, Aggarwal N, Taneja DK (2004) Tuberculosis Trend among Household Contacts of TB Patients. Indian J Comm Med 29: 1-3.
3. Guwatudde D, Nakakeeto M, Jones-Lopez EC, Maganda A, Chiunda A, et al. (2003) Tuberculosis in Household Contacts of Infectious Cases in Kampala, Uganda. Am J Epidemiol 158: 887-898.
4. Lemos AC, Matos ED, Pedral-Sampaio DB, Netto EM (2004) Risk of Tuberculosis among Household Contacts in Salvador, Bahia. Braz J Infect Dis 8: 424-430.
5. Comstock G (1982) Epidemiology of Tuberculosis. Am J Respir Dis 125: 8-15.
6. Ferraz JC, Melo FB, Albuquerque MF, Montes C, Abath FG (2006) Immune factors and immunoregulation in tuberculosis. Braz J Med Biol Res 39: 1387-1397.
7. Dorman SE, Picard C, Lammas D, Heyne K, van Dissel JT, et al. (2004) Clinical features of dominant and recessive interferon gamma receptor 1 deficiencies. Lancet 364: 2113-2121.
8. Altare F, Jouanguy E, Lamhamedi-Cherradi S, Fondaneche MC, Fizame C, et al. (1998) A causative relationship between mutant IFNgR1 alleles and impaired cellular response to IFN gamma in a compound heterozygous child. Am J Hum Genet 62: 723-726.
9. Pacheco AG, Cardoso CC, Moraes MO (2008) IFNG +874T/A, IL10 - 1082G/A and TNF - 308G/A polymorphisms in association with tuberculosis susceptibility: a meta-analysis study. Hum Genet 123: 477-484.
10. Pravica V, Perrey C, Stevens A, Lee JH, Hutchinson IV (2000) A single nucleotide polymorphism in the first intron of human interferon g gene: absolute correlation with a polymorphic C/A microsatellite marker of high interferon g production. Human Immunology 61: 863-866.
11. Rees LE, Wood NA, Gillespie KM, Lai KN, Gaston K, et al. (2002) The interleukin 10-1082 G/A polymorphism: allele frequency in different populations and functional significance. Cell Mol Life Sci 59: 560-569.
12. Ates O, Musellim B, Ongen G, Topal-Sarikaya A (2007) Interleukin-10 and Tumor Necrosis Factor-a Gene Polymorphism in Tuberculosis. J Clin Immunol. pp 1-5.
13. Oh JH, Yang CS, Noh YK, Kweon YM, Jung S-S, et al. (2007) Polymorphism of interleukin-10 and tumour necrosis factor-a genes are associated with newly diagnosed and recurrent pulmonary tuberculosis. Respirology 12: 594-598.
14. Flynn JL, Chan J, Triebold KJ, Dalton DK, Stewart TA, et al. (1993) An Essential role for Interferon gamma in resistance to Mycobacterium tuberculosis infection. J Exp Med 178: 2249-2254.
15. O'Garra A, Vieira PL, Vieira P, Goldfeld AE (2004) IL-10 producing and naturally occurring CD4+ Tregs: limiting collateral damage. J Clin Invest 114: 1372-1378.
16. Jamil B, Shahid F, Hasan Z, Nasir N, Razzaki T, et al. (2007) Interferongamma/IL10 ratio defines the disease severity in pulmonary and extra pulmonary tuberculosis. Tuberculosis (Edinb) 87: 279-287.
17. Mehdi SQ, Ayub Q, Qamar R, Mohyuddin A, Mansoor A, et al. (2002) Perspectives on Human Genome Diversity within Pakistan using Y Chromosomal and Autosomal Microsatellite Markers. In: Sener B, ed (2002) Biodiversity: Biomolecular Aspects of Biodiversity and Innovative Utilization Kluwer Academic/Plenum Publishers. pp 35-47.
18. Bagheri M, Abdi-Rad I, Omrani D, Khalkhali HR (2006) Heterogeneity of cytokine single-nucleotide polymorphsims among the Iranian and in the other East-South Asian populations. Transfusion Medicine 16: 192-199.
19. Takiff HE (2007) Host Genetics and Susceptibility. In: Palomino JC, Leao SC, Ritacco V, eds (2007) Tuberculosis 2007 - From Basic Science to Patient Care. Brazil. pp 207-262.
20. Lio D, Marino V, Serauto A, Gioia V, Scola L, et al. (2002) Genotype frequencies of the +874T-> A single nucleotide polymorphism in the first intron of the interferon-gamma gene in a sample of Sicilian patients affected by tuberculosis. Eur J Immunogenet 29: 371-374.
21. Rossouw M, Nel HJ, Cooke GS, van Helden PD, Hoal EG (2003) Association between tuberculosis and a polymorphic NFkappaB binding site in the interferon gamma gene. Lancet 361: 1871-1872.
22. Tso HW, Ip WK, Chong WP, Tam CM, Chiang AK, et al. (2005) Association of interferon gamma and interleukin 10 genes with tuberculosis in Hong Kong Chinese. Genes Immun 6: 358-363.
23. Lopez-Maderuelo D, Arnalich F, Serantes R, Gonzalez A, Codoceo R, et al. (2003) Interferon-gamma and interleukin-10 gene polymorphisms in pulmonary tuberculosis 5691. Am J Respir Crit Care Med 167: 970-975.
24. Oral HB, Budak F, Uzaslan EK, Basturk B, Bekar A, et al. (2006) Interleukin-10 (IL-10) gene polymorphism as a potential host susceptibility factor in tuberculosis. Cytokine 35: 143-147.
25. Sallakci N, Coskun M, Berber Z, Guürkan F, Kocamaz H, et al. (2007) Interferon-gamma gene+874T-A polymorphism is associated with tuberculosis and gamma interferon response. Tuberculosis 87: 225-230.
26. Etokebe G, Bulat-Kardum L, Johansen M, Knezevic J, Balen S, et al. (2006) Interferon-gamma gene (T874A and G2109A) polymorphisms are associated with microscopy-positive tuberculosis. Scand J Immunol 63: 136-141.
27. Moran A, Ma X, Reich RA, Graviss EA (2007) No association between the +874T/A single nucleotide polymorphism in the IFN-g gene and susceptibility to TB. Int J Tuberc Lung Dis 11: 113-115.
28. Vidyarani M, Selvaraj P, Adnand AP, Jawahar MS, Adhilakshmi AR, et al. (2006) Interferon gamma (IFNγ) & interleukin-4 (IL-4) gene variants & cytokine levels of pulmonary tuberculosis. Indian J Med Res 124: 403-410.
29. Henao MI, Montes C, Paris SC, Garcia LF (2006) Cytokine gene polymorphisms in Colombian patients with different clinical presentations of tuberculosis. Tuberculosis 86: 11-19.
30. Cooke GS, Campbell SJ, Sillah J, Gustafson P, Bah B, et al. (2006) Polymorphism within the Interferon-g/ Receptor Complex is associated with Pulmonary Tuberculosis. Am J Respir Crit Care Med 174: 339-343.
31. Flores-Villanueva PO, Ruiz-Morales JA, Song CH, Flores LM, Jo EK, et al. (2005) A functional promoter polymorphism in monocyte chemoattractant protein-1 is associated with increased susceptibility to pulmonary tuberculosis. J Exp Med 202: 1649-1658.
32. Sahiratmadja E, Alisjahbana B, de Boer T, Adnan I, Maya A, et al. (2007) Dynamic changes in pro- and anti-inflammatory cytokine profiles and gamma interferon receptor signaling integrity correlate with tuberculosis disease activity and response to curative treatment. Infect Immun 75: 820-829.
33. Turner DM, Williams DM, Sankaran D, Lazarus M, Sinnott PJ, et al. (1997) An Investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogen 24: 1-8.
34. Hussain R, Kaleem A, Shahid F, Dojki M, Jamil B, et al. (2002) Cytokine profiles using whole blood assays can discriminate between tuberculosis patients and healthy endemic controls in BCG-vaccinated population. J Immunol Meth 264: 95-108.
35. Bellamy R (2003) Susceptibility to mycobacterial infections: the importance of host genetics. Genes Immun 4: 4-11.
36. Shin HD, Park BL, Kim LH, Cheong HS, Lee IH, et al. (2005) Common interleukin 10 polymorphism associated with deceased risk of tuberculosis. Exp Mol Med 37: 128-132.
37. Scola L, Crivello A, Marino V, Gioia V, Serauto A, et al. (2003) IL-10 and TNF-alpha polymorphisms in a sample of Sicilian patients affected by tuberculosis: implication for ageing and life span expectancy. Mech Ageing Dev 124: 569-572.
38. Delgado JC, Baena A, Thim S, Goldfeld AE (2002) Ethnic-Specific genetic associations with pulmonary tuberculosis. J Infect Dis 186: 1463-1468.
39. Hussain R, Talat N, Shahid F, Dawood G (2007) Longitudinal tracking of cytokines after acute exposure to Tuberculosis: Association of Distinct Cytokine patterns with protection and disease development. Clin Vaccine Immunol 14: 1578-1586.
40. Maher D, Chaulet P, Spinaci S, Harries A (1997) Treatment of Tuberculosis - Guidelines for National Programmes World Health Organization. pp 1-78.
41. Perrey C, Pravica V, Sinnott PJ, Hutchinson IV (1998) Genotyping for polymorphisms in interferon-gamma, interleukin-10, transforming growth factor-beta 1 and tumor necrosis factor-alpha genes: a technical report. Transpl Immunol 6: 193-197.