PTCH1+/- dermal fibroblasts isolated from healthy skin of Gorlin syndrome patients exhibit features of carcinoma associated fibroblasts

PLoS ONE

Volumn 4, Issue 3, 2009, Pages

  Valin, Alexandre ^a   Barnay Verdier, Stéphanie ^b   Robert, Thomas ^a   Ripoche, Hugues ^a   Brellier, Florence ^c   Chevallier Lagante, Odile ^a   Avril, Marie Françoise ^d   Magnaldo, Thierry ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

^b CENTRE DE RECHERCHE DES CORDELIERS   (France)

^c FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^d UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN; BONE MORPHOGENETIC PROTEIN; CATENIN; INTERSTITIAL COLLAGENASE; MESSENGER RNA; PROTEIN PATCHED 1; STROMAL CELL DERIVED FACTOR 1ALPHA; STROMELYSIN; WNT PROTEIN; BETA CATENIN; CELL SURFACE RECEPTOR; CYTOKINE; GREM1 PROTEIN, HUMAN; MATRIX METALLOPROTEINASE; PATCHED RECEPTORS; SIGNAL PEPTIDE;

ARTICLE; BASAL CELL CARCINOMA; BASAL CELL NEVUS SYNDROME; CANCER SUSCEPTIBILITY; CELL DIFFERENTIATION; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; FIBROBLAST; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; GENE TARGETING; GENOME ANALYSIS; HUMAN; HUMAN CELL; KERATINOCYTE; MISSENSE MUTATION; NONSENSE MUTATION; NUCLEOTIDE SEQUENCE; BASEMENT MEMBRANE; DNA MICROARRAY; ENZYMOLOGY; GENETICS; METABOLISM; PATHOLOGY; SKIN; SKIN TUMOR;

BASAL CELL NEVUS SYNDROME; BASEMENT MEMBRANE; BETA CATENIN; CARCINOMA, BASAL CELL; CYTOKINES; FIBROBLASTS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MATRIX METALLOPROTEINASES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, CELL SURFACE; RNA, MESSENGER; SKIN; SKIN NEOPLASMS; WNT PROTEINS;

EID: 62849085539     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004818     Document Type: Article

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