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Volumn 83, Issue 6, 2009, Pages 2756-2764

Abrogation of the postmitotic checkpoint contributes to polyploidization in human papillomavirus E7-expressing cells

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; PROTEIN E6; PROTEIN E7; RETINOBLASTOMA PROTEIN; TUBULIN;

EID: 62749205802     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02149-08     Document Type: Article
Times cited : (26)

References (42)
  • 1
    • 0034767429 scopus 로고    scopus 로고
    • Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1
    • Andreassen, P. R., O. D. Lohez, F. B. Lacroix, and R. L. Margolis. 2001. Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1. Mol. Biol. Cell 12:1315-1328.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 1315-1328
    • Andreassen, P.R.1    Lohez, O.D.2    Lacroix, F.B.3    Margolis, R.L.4
  • 2
    • 0030929838 scopus 로고    scopus 로고
    • DNA rereplication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRb function
    • Di Leonardo, A., S. H. Khan, S. P. Linke, V. Greco, G. Seidita, and G. M. Wahl. 1997. DNA rereplication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRb function. Cancer Res. 57:1013-1019.
    • (1997) Cancer Res , vol.57 , pp. 1013-1019
    • Di Leonardo, A.1    Khan, S.H.2    Linke, S.P.3    Greco, V.4    Seidita, G.5    Wahl, G.M.6
  • 3
    • 33847391958 scopus 로고    scopus 로고
    • A virus causes cancer by inducing massive chromosomal instability through cell fusion
    • Duelli, D. M., H. M. Padilla-Nash, D. Berman, K. M. Murphy, T. Ried, and Y. Lazebnik. 2007. A virus causes cancer by inducing massive chromosomal instability through cell fusion. Curr. Biol. 17:431-437.
    • (2007) Curr. Biol , vol.17 , pp. 431-437
    • Duelli, D.M.1    Padilla-Nash, H.M.2    Berman, D.3    Murphy, K.M.4    Ried, T.5    Lazebnik, Y.6
  • 4
    • 0034730196 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle
    • Duensing, S., L. Y. Lee, A. Duensing, J. Basile, S. Piboonniyom, S. Gonzalez, C. P. Crum, and K. Munger. 2000. The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle. Proc. Natl. Acad. Sci. USA 97:10002-10007.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 10002-10007
    • Duensing, S.1    Lee, L.Y.2    Duensing, A.3    Basile, J.4    Piboonniyom, S.5    Gonzalez, S.6    Crum, C.P.7    Munger, K.8
  • 5
    • 0036897282 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability
    • Duensing, S., and K. Munger. 2002. The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability. Cancer Res. 62:7075-7082.
    • (2002) Cancer Res , vol.62 , pp. 7075-7082
    • Duensing, S.1    Munger, K.2
  • 6
    • 0024535228 scopus 로고
    • The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
    • Dyson, N., P. M. Howley, K. Munger, and E. Harlow. 1989. The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 243:934-937.
    • (1989) Science , vol.243 , pp. 934-937
    • Dyson, N.1    Howley, P.M.2    Munger, K.3    Harlow, E.4
  • 7
    • 3142673498 scopus 로고    scopus 로고
    • Regulation of cell cycle progression and apoptosis by the papillomavirus E6 oncogene
    • Fan, X., and J. J. Chen. 2004. Regulation of cell cycle progression and apoptosis by the papillomavirus E6 oncogene. Crit. Rev. Eukaryot. Gene Expr. 14:183-202.
    • (2004) Crit. Rev. Eukaryot. Gene Expr , vol.14 , pp. 183-202
    • Fan, X.1    Chen, J.J.2
  • 8
    • 0033947269 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E7 oncogene is required for the productive stage of the viral life cycle
    • Flores, E. R., B. L. Allen-Hoffmann, D. Lee, and P. F. Lambert. 2000. The human papillomavirus type 16 E7 oncogene is required for the productive stage of the viral life cycle. J. Virol. 74:6622-6631.
    • (2000) J. Virol , vol.74 , pp. 6622-6631
    • Flores, E.R.1    Allen-Hoffmann, B.L.2    Lee, D.3    Lambert, P.F.4
  • 9
    • 27144507868 scopus 로고    scopus 로고
    • Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells
    • Fujiwara, T., M. Bandi, M. Nitta, E. V. Ivanova, R. T. Bronson, and D. Pellman. 2005. Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells. Nature 437:1043-1047.
    • (2005) Nature , vol.437 , pp. 1043-1047
    • Fujiwara, T.1    Bandi, M.2    Nitta, M.3    Ivanova, E.V.4    Bronson, R.T.5    Pellman, D.6
  • 10
    • 0030827303 scopus 로고    scopus 로고
    • Funk, J. O., S. Waga, J. B. Harry, E. Espling, B. Stillman, and D. A, Galloway. 1997. Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein. Genes Dev. 11:2090-2100.
    • Funk, J. O., S. Waga, J. B. Harry, E. Espling, B. Stillman, and D. A, Galloway. 1997. Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein. Genes Dev. 11:2090-2100.
  • 15
    • 33646124023 scopus 로고    scopus 로고
    • Induction of tetraploidy through loss of p53 and upregulation of Plk1 by human papillomavirus type-16 E6
    • Incassati, A., D. Patel, and D. J. McCance. 2006. Induction of tetraploidy through loss of p53 and upregulation of Plk1 by human papillomavirus type-16 E6. Oncogene. 25:2444-2451.
    • (2006) Oncogene , vol.25 , pp. 2444-2451
    • Incassati, A.1    Patel, D.2    McCance, D.J.3
  • 16
    • 33750220492 scopus 로고    scopus 로고
    • RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts
    • Iovino, F., L. Lentini, A. Amato, and A. Di Leonardo. 2006. RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts. Mol. Cancer 5:38.
    • (2006) Mol. Cancer , vol.5 , pp. 38
    • Iovino, F.1    Lentini, L.2    Amato, A.3    Di Leonardo, A.4
  • 17
    • 0030756473 scopus 로고    scopus 로고
    • The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2
    • Jones, D. L., R. M. Alani, and K. Munger. 1997. The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2. Genes Dev. 11:2101-2111.
    • (1997) Genes Dev , vol.11 , pp. 2101-2111
    • Jones, D.L.1    Alani, R.M.2    Munger, K.3
  • 18
    • 0032005132 scopus 로고    scopus 로고
    • p53 and pRb prevent rereplication in response to microtubule inhibitors by mediating a reversible G1 arrest
    • Khan, S. H., and G. M. Wahl. 1998. p53 and pRb prevent rereplication in response to microtubule inhibitors by mediating a reversible G1 arrest. Cancer Res. 58:396-401.
    • (1998) Cancer Res , vol.58 , pp. 396-401
    • Khan, S.H.1    Wahl, G.M.2
  • 19
    • 0031931414 scopus 로고    scopus 로고
    • Characterization of the p53-dependent postmitotic checkpoint following spindle disruption
    • Lanni, J. S., and T. Jacks. 1998. Characterization of the p53-dependent postmitotic checkpoint following spindle disruption. Mol. Cell. Biol. 18: 1055-1064.
    • (1998) Mol. Cell. Biol , vol.18 , pp. 1055-1064
    • Lanni, J.S.1    Jacks, T.2
  • 20
    • 0036708499 scopus 로고    scopus 로고
    • Functional inactivation of pRB results in aneuploid mammalian cells after release from a mitotic block
    • Lentini, L., L. Pipitone, and A. Di Leonardo. 2002. Functional inactivation of pRB results in aneuploid mammalian cells after release from a mitotic block. Neoplasia 4:380-387.
    • (2002) Neoplasia , vol.4 , pp. 380-387
    • Lentini, L.1    Pipitone, L.2    Di Leonardo, A.3
  • 21
    • 34047249459 scopus 로고    scopus 로고
    • p53-independent abrogation of a postmitotic checkpoint contributes to HPV E6-induced polyploidy
    • Liu, Y., S. A. Heilman, D. Illanes, G. Sluder, and J. J. Chen. 2007. p53-independent abrogation of a postmitotic checkpoint contributes to HPV E6-induced polyploidy. Cancer Res. 67:2603-2610.
    • (2007) Cancer Res , vol.67 , pp. 2603-2610
    • Liu, Y.1    Heilman, S.A.2    Illanes, D.3    Sluder, G.4    Chen, J.J.5
  • 22
    • 0037373258 scopus 로고    scopus 로고
    • G1 tetraploidy checkpoint and the suppression of tumorigenesis
    • Margolis, R. L., O. D. Lohez, and P. R. Andreassen. 2003. G1 tetraploidy checkpoint and the suppression of tumorigenesis. J. Cell. Biochem. 88:673-683.
    • (2003) J. Cell. Biochem , vol.88 , pp. 673-683
    • Margolis, R.L.1    Lohez, O.D.2    Andreassen, P.R.3
  • 23
    • 0030731673 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E7 binds to the conserved carboxy-terminal region of the TATA box binding protein and this contributes to E7 transforming activity
    • Massimi, P., D. Pirn, and L. Banks. 1997. Human papillomavirus type 16 E7 binds to the conserved carboxy-terminal region of the TATA box binding protein and this contributes to E7 transforming activity. J. Gen. Virol. 78: 2607-2613.
    • (1997) J. Gen. Virol , vol.78 , pp. 2607-2613
    • Massimi, P.1    Pirn, D.2    Banks, L.3
  • 24
    • 0037084163 scopus 로고    scopus 로고
    • Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells
    • Meraldi, P., R. Honda, and E. A. Nigg. 2002. Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells. EMBO J. 21:483-492.
    • (2002) EMBO J , vol.21 , pp. 483-492
    • Meraldi, P.1    Honda, R.2    Nigg, E.A.3
  • 25
    • 0037178719 scopus 로고    scopus 로고
    • Segregating sister genomes: The molecular biology of chromosome separation
    • Nasmyth, K. 2002. Segregating sister genomes: the molecular biology of chromosome separation. Science 297:559-565.
    • (2002) Science , vol.297 , pp. 559-565
    • Nasmyth, K.1
  • 27
    • 1242338787 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E6 and E7 cause polyploidy in human keratinocytes and up-regulation of G2-M-phase proteins
    • Patel, D., A. Incassati, N. Wang, and D. J. McCance. 2004. Human papillomavirus type 16 E6 and E7 cause polyploidy in human keratinocytes and up-regulation of G2-M-phase proteins. Cancer Res. 64:1299-1306.
    • (2004) Cancer Res , vol.64 , pp. 1299-1306
    • Patel, D.1    Incassati, A.2    Wang, N.3    McCance, D.J.4
  • 28
    • 0037168189 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E6 oncogene induces premature mitotic chromosome segregation
    • Plug-Demaggio, A. W., and J. K. McDougall. 2002. The human papillomavirus type 16 E6 oncogene induces premature mitotic chromosome segregation. Oncogene 21:7507-7513.
    • (2002) Oncogene , vol.21 , pp. 7507-7513
    • Plug-Demaggio, A.W.1    McDougall, J.K.2
  • 29
    • 0032563638 scopus 로고    scopus 로고
    • Entry into mitosis in vertebrate somatic cells is guarded by a chromosome damage checkpoint that reverses the cell cycle when triggered during early but not late prophase
    • Rieder, C. L., and R. W. Cole. 1998. Entry into mitosis in vertebrate somatic cells is guarded by a chromosome damage checkpoint that reverses the cell cycle when triggered during early but not late prophase. J. Cell Biol. 142: 1013-1022.
    • (1998) J. Cell Biol , vol.142 , pp. 1013-1022
    • Rieder, C.L.1    Cole, R.W.2
  • 30
    • 0027358723 scopus 로고
    • The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • Scheffner, M., J. M. Huibregtse, R. D. Vierstra, and P. M. Howley. 1993. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 75:495-505.
    • (1993) Cell , vol.75 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howley, P.M.4
  • 31
    • 27144518175 scopus 로고    scopus 로고
    • Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines
    • Shi, Q., and R. W. King. 2005. Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines. Nature 437:1038-1042.
    • (2005) Nature , vol.437 , pp. 1038-1042
    • Shi, Q.1    King, R.W.2
  • 32
    • 1642412809 scopus 로고    scopus 로고
    • The good, the bad and the ugly: The practical consequences of centrosome amplification
    • Sluder, G., and J. J. Nordberg. 2004. The good, the bad and the ugly: the practical consequences of centrosome amplification. Curr. Opin. Cell Biol. 16:49-54.
    • (2004) Curr. Opin. Cell Biol , vol.16 , pp. 49-54
    • Sluder, G.1    Nordberg, J.J.2
  • 34
    • 0032952584 scopus 로고    scopus 로고
    • p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption
    • Stewart, Z. A., S. D. Leach, and J. A. Pietenpol. 1999. p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption. Mol. Cell. Biol. 19:205-215.
    • (1999) Mol. Cell. Biol , vol.19 , pp. 205-215
    • Stewart, Z.A.1    Leach, S.D.2    Pietenpol, J.A.3
  • 35
    • 0035085998 scopus 로고    scopus 로고
    • p53 signaling and cell cycle checkpoints
    • Stewart, Z. A., and J. A. Pietenpol. 2001. p53 signaling and cell cycle checkpoints. Chem. Res. Toxicol. 14:243-263.
    • (2001) Chem. Res. Toxicol , vol.14 , pp. 243-263
    • Stewart, Z.A.1    Pietenpol, J.A.2
  • 36
    • 0030687987 scopus 로고    scopus 로고
    • Kinetochore localization of murine Bubl is required for normal mitotic timing and checkpoint response to spindle damage
    • Taylor, S. S., and F. McKeon. 1997. Kinetochore localization of murine Bubl is required for normal mitotic timing and checkpoint response to spindle damage. Cell 89:727-735.
    • (1997) Cell , vol.89 , pp. 727-735
    • Taylor, S.S.1    McKeon, F.2
  • 37
    • 0031930282 scopus 로고    scopus 로고
    • Human papillomavirus oncoproteins E6 and E7 independently abrogate the mitotic spindle checkpoint
    • Thomas, J. T., and L. A. Laimins. 1998. Human papillomavirus oncoproteins E6 and E7 independently abrogate the mitotic spindle checkpoint. J. Virol. 72:1131-1137.
    • (1998) J. Virol , vol.72 , pp. 1131-1137
    • Thomas, J.T.1    Laimins, L.A.2
  • 38
    • 0031577693 scopus 로고    scopus 로고
    • The human papillomaviras-16 E6 oncoprotein decreases the vigilance of mitotic checkpoints
    • Thompson, D. A., G. Belinsky, T. H. Chang, D. L. Jones, R. Schlegel, and K. Munger. 1997. The human papillomaviras-16 E6 oncoprotein decreases the vigilance of mitotic checkpoints. Oncogene 15:3025-3035.
    • (1997) Oncogene , vol.15 , pp. 3025-3035
    • Thompson, D.A.1    Belinsky, G.2    Chang, T.H.3    Jones, D.L.4    Schlegel, R.5    Munger, K.6
  • 39
    • 2942679807 scopus 로고    scopus 로고
    • Cell cycle progression after cleavage failure: Mammalian somatic cells do not possess a "tetraploidy checkpoint
    • Uetake, Y., and G. Sluder. 2004. Cell cycle progression after cleavage failure: mammalian somatic cells do not possess a "tetraploidy checkpoint". J. Cell Biol. 165:609-615.
    • (2004) J. Cell Biol , vol.165 , pp. 609-615
    • Uetake, Y.1    Sluder, G.2
  • 40
    • 4644281946 scopus 로고    scopus 로고
    • Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy
    • Vogel, C., A. Kienitz, I. Hofmann, R. Muller, and H. Bastians. 2004. Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy. Oncogene 23:6845-6853.
    • (2004) Oncogene , vol.23 , pp. 6845-6853
    • Vogel, C.1    Kienitz, A.2    Hofmann, I.3    Muller, R.4    Bastians, H.5
  • 41
  • 42
    • 0036559896 scopus 로고    scopus 로고
    • Papillomaviruses and cancer: From basic studies to clinical application
    • zur Hausen, H. 2002. Papillomaviruses and cancer: from basic studies to clinical application. Nat. Rev. Cancer 2:342-350.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 342-350
    • zur Hausen, H.1


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