Divergent synthesis of isoindolo[2,1-a]indole and indolo[1,2-a]indole through copper-catalysed C- and N-arylations

Tetrahedron Letters

Volumn 50, Issue 18, 2009, Pages 2129-2131

  Barbero, Nekane ^a   SanMartin, Raul ^a   Domínguez, Esther ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Arylation; Copper catalysts; Indoles

Indexed keywords

CARBON; COPPER; INDOLE DERIVATIVE; INDOLO[1,2 A]INDOLE; ISOINDOLO[2,1 A]INDOLE; NITROGEN; UNCLASSIFIED DRUG;

ARTICLE; ARYLATION; CATALYST; CHEMICAL BOND; DRUG STRUCTURE; DRUG SYNTHESIS;

EID: 62649157221     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.02.175     Document Type: Article

References (47)

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46. 4 and concentrated in vacuo. The resulting residue was purified by flash chromatography (10% AcOEt/n-hexane) to afford the target tetracyclic product 1 as a white powder (52.3 mg, 88%). The physical data were compared with those found in the literature. See: Ref. 9c.
47. 4 and concentrated in vacuo. The resulting residue was purified by flash chromatography (10% AcOEt/n-hexane) to afford the target tetracyclic product 2 as a white powder (51.0 mg, 88%). For physical data see Supplementary data.