Anti-apoptotic and anti-inflammatory effects of hydrogen sulfide in a rat model of regional myocardial l/R

Shock

Volumn 31, Issue 3, 2009, Pages 267-274

  Sivarajah, Ahila ^a   Collino, Massimo ^b   Yasin, Mohammed ^a   Benetti, Elisa ^b   Gallicchio, Margherita ^b   Mazzon, Emanuela ^c   Cuzzocrea, Salvatore ^d   Fantozzi, Roberto ^b   Thiemermann, Christoph ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF TURIN   (Italy)

^c IRCCS CENTRO NEUROLESI BONINO PULEJO   (Italy)

^d UNIVERSITY OF MESSINA   (Italy)

Author keywords

Apoptosis; Hydrogen sulfide; Infarct size; Inflammation and regional myocardial infarction

Indexed keywords

3 NITROTYROSINE; 5 HYDROXYDECANOIC ACID; CASPASE 9; CYSTATHIONINE BETA SYNTHASE; CYSTATHIONINE GAMMA LYASE; HYDROGEN SULFIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOPEROXIDASE; POTASSIUM CHANNEL BLOCKING AGENT; PROTEIN BCL 2; SODIUM CHLORIDE; SODIUM HYDROGEN SULFIDE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; 3-NITROTYROSINE; 5-HYDROXYDECANOIC ACID; ANTIARRHYTHMIC AGENT; CARDIOTONIC AGENT; DECANOIC ACID DERIVATIVE; DRUG DERIVATIVE; HYDROXYACID; MUSCLE PROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; SODIUM BISULFIDE; SULFIDE; TYROSINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; BOLUS INJECTION; BRAIN INFARCTION SIZE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; MALE; NEUTROPHIL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; RAT; REPERFUSION INJURY; WISTAR RAT; ACTIVE TRANSPORT; ANIMAL; CELL NUCLEUS; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PATHOLOGY; PHOSPHORYLATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; CARDIOTONIC AGENTS; CELL NUCLEUS; DECANOIC ACIDS; DISEASE MODELS, ANIMAL; DRUG ANTAGONISM; HYDROXY ACIDS; MALE; MALONDIALDEHYDE; MUSCLE PROTEINS; MYOCARDIAL REPERFUSION INJURY; NEUTROPHILS; PHOSPHORYLATION; RATS; RATS, WISTAR; SULFIDES; TYROSINE;

EID: 62449302475     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e318180ff89     Document Type: Article

References (39)

1. Bcehning D, Snyder SH: Novel neural modulators. Annu Rev Neurosci 26: 105-131, 2003.
2. Geng B, Chang L, Pan C, Qi Y, Zhao J, Pang Y, Du J, Tang C: Endogenous hydrogen sulfide regulation of myocardial injury induced by isoproterenol. Biochem Biophys Res Commun 318:756-763, 2004.
3. Geng B, Yang J, Qi Y, Zhao J, Pang Y, Du J, Tang C: H2S generated by heart in rat and its effects on cardiac function. Biochem Biophys Res Commun 313: 362-368, 2004.
4. Cheng Y, Ndisang JF, Tang G, Cao K, Wang R: Hydrogen sulfide-induced relaxation of resistance mesenteric artery beds of rats. Am J Physiol Heart Circ Physiol 287:H2316-H2323, 2004.
5. Zhao W, Zhang J, Lu Y, Wang R: The vasorelaxant effect of H(2)S as a novel endogenous gaseous K(ATP) channel opener. EMBO J 20:6008-6016, 2001.
6. Collin M, Anuar FB, Murch O, Bhatia M, Moore PK, Thiemermann C: Inhibition of endogenous hydrogen sulfide formation reduces the organ injury caused by endotoxemia. Br J Pharmacol 146:498-505, 2005.
7. Li L, Bhatia M, Zhu YZ, Zhu YC, Ramnath RD, Wang ZJ, Anuar FB, Whiteman M, Salto-Tellez M, Moore PK: Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse. FASEB J 19:1196-1198, 2005.
8. Zhang H, Hegde A, Ng SW, Adhikari S, Moochhala SM, Bhatia M: Hydrogen sulfide up-regulates substance p in polymicrobial sepsis-associated lung injury. J Immunol 179:4153-160, 2007.
9. Zanardo RC, Brancaleone V, Distrutti E, Fiorucci S, Cirino G, Wallace JL: Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation. FASEB J 20:2118-2120, 2006.
10. Sivarajah A, McDonald MC, Thiemermann C: The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat. Shock 26:154-161, 2006.
11. Zhu YZ, Wang ZJ, Ho P, Loke YY, Zhu YC, Huang SH, Tan CS, Whiteman M, Lu J, Moore PK: Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats. J Appl Physiol 102:261-268, 2007.
12. 2S) protects against regional myocardial ischemia-reperfusion injury-evidence for a role of K ATP channels. Basic Res Cardiol 101:53-60, 2006.
13. Wayman NS, Hattori Y, McDonald MC, Mota-Filipe H, Cuzzocrea S, Pisano B, Chatterjee PK, Thiemermann C: Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size. FASEB J 16:1027-1040, 2002.
14. Bailer D, Zipfel J, Hellige G: Usefulness and limitations of myocardial oxygen consumption indices. Clin Cardiol 3:212-213, 1980.
15. Nachlas MM, Shnifka TK: Macroscopic identification of early myocardial infarcts by alterations in dehydrogenase activity. Am J Pathol 42:379-405, 1963.
16. Mitra R, Morad M: A uniform enzymatic method for dissociation of myocytes from hearts and stomachs of vertebrates. Am J Physiol 249:H1056-H1060, 1985.
17. Diez C, Simm A: Gene expression in rod shaped cardiac myocytes, sorted by flow cytometry. Cardiovasc Res 40:530-537, 1998.
18. Collino M, Aragno M, Mastrocola R, Benetti E, Gallicchio M, Dianzani C, Danni O, Thiemermann C, Fantozzi R: Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: effects of the PPAR-alpha agonist WY14643. Free Radic Biol Med 41:579-589, 2006.
19. Ohkawa H, Ohishi N, Yagi K: Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95:351-358, 1979.
20. Laight DW, Lad N, Woodward B, Waterfall JF: Assessment of myeloperoxidase activity in renal tissue after ischemia/reperfusion. Eur J Pharmacol 292: 81-88, 1994.
21. + channels. Possible mechanism of cardioprotection. Circ Res 81:1072-1082, 1997.
22. Liu Y, Sato T, O'Rourke B, Marban E: Mitochondrial ATP-dependent potassium channels: novel effectors of cardioprotection? Circulation 97:2463-2469, 1998.
23. Hide EJ, Thiemermann C: Limitation of myocardial infarct size in the rabbit by ischaemic preconditioning is abolished by sodium 5-hydroxydecanoate. Cardiovasc Res 31:941-946, 1996.
24. Kimura Y, Kimura H: Hydrogen sulfide protects neurons from oxidative stress. FASEBJ 18:1165-1167, 2004.
25. Whiteman M, Armstrong JS, Chu SH, Jia-Ling S, Wong BS, Cheung NS, Halliwell B, Moore PK: The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite 'scavenger'? J Neurochem 90:765-768, 2004.
26. Gottlieb RA, Burleson KO, Kloner RA, Babior BM, Engler RL: Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest 94:1621-1628, 1994.
27. Maulik N, Yoshida T, Das DK: Oxidative stress developed during the reperfusion of ischemic myocardium induces apoptosis. Free Radic Biol Med 24: 869-875, 1998.
28. Otsu K, Yamashita N, Nishida K, Hirotani S, Yamaguchi O, Watanabe T, Hikoso S, Higuchi Y, Matsumura Y, Maruyama M, et al.: Disruption of a single copy of the p38alpha MAP kinase gene leads to cardioprotection against ischemia-reperfusion. Blochem Biophys Res Commun 302:56-60, 2003.
29. Ma XL, Kumar S, Gao F, Louden CS, Lopez BL, Christopher TA, Wang C, Lee JC, Feuerstein GZ, Yue TL: Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion. Circulation 99:1685-1691, 1999.
30. Ferrandi C, Ballerio R, Gaillard P, Giachetti C, Carboni S, Vitte PA, Gotteland JP, Cirillo R: Inhibition of c-Jun N-terminal kinase decreases cardiomyocyte apoptosis and infarct size after myocardial ischemia and reperfusion in anaesthetized rats. Br J Pharmacol 142:953-960, 2004.
31. Capano M, Crompton M: Bax translocates to mitochondria of heart cells during simulated ischaemia: involvement of AMP-activated and p38 mitogen-activated protein kinases. Biochem J 395:57-64, 2006.
32. Manning AM, Bell FP, Rosenbloom CL, Chosay JG, Simmons CA, Northrup JL, Shebuski RJ, Dunn CJ, Anderson DC: NF-kappa B is activated during acute inflammation in vivo in association with elevated endothelial cell adhesion molecule gene expression and leukocyte recruitment. J Inflamm 45: 283-296, 1995.
33. Carter AB, Knudtson KL, Monick MM, Hunninghake GW: The p38 mitogen-activated protein kinase is required for NF-kappaB-dependent gene expression. The role of TATA-binding protein (TBP). J Biol Chem 274: 30858-30863, 1999.
34. Vanden BW, Plaisance S, Boone E, De BK, Schmitz ML, Fiers W, Haegeman G: p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor. J Biol Chem 273:3285-3290, 1998.
35. Distrutti E, Sediari L, Mencarelli A, Renga B, Orlandi S, Antonelli E, Roviezzo F, Morelli A, Cirino G, Wallace JL, et al.: Evidence that hydrogen sulfide exerts antinociceptive effects in the gastrointestinal tract by activating KATP channels. J Pharmacol Exp Ther 316:325-335, 2006.
36. Fiorucci S, Distrutti E, Cirino G, Wallace JL: The emerging roles of hydrogen sulfide in the gastrointestinal tract and liver. Gastroenterology 131:259-271, 2006.
37. Blackstone E, Morrison M, Roth MB: H2S induces a suspended animation-like state in mice. Science 308:518, 2005.
38. Elrod JW, Calvert JW, Morrison J, Doeller JE, Kraus DW, Tao L, Jiao X, Scalia R, Kiss L, Szabo C, et al.: Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function. Proc Natl Acad Sci U S A 104:15560-15565, 2007.
39. Akao M, Ohler A, O'Rourke B, Marban E: Mitochondrial ATP-sensitive potassium channels inhibit apoptosis induced by oxidative stress in cardiac cells. Circ Res 88:1267-1275, 2001.