Better estimation of protein-DNA interaction parameters improve prediction of functional sites

BMC Biotechnology

Volumn 8, Issue , 2008, Pages

  Nagaraj, Vijayalakshmi H ^a   O'Flanagan, Ruadhan A ^b   Sengupta, Anirvan M ^a  

^a RUTGERS UNIVERSITY   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; BINDING ENERGY; BIOINFORMATICS; DISSOCIATION; DNA; DNA SEQUENCES; ELECTROPHORETIC MOBILITY; ESCHERICHIA COLI; GENES; NUCLEIC ACIDS; TRANSCRIPTION; TRANSCRIPTION FACTORS;

ACTIVATOR PROTEINS; BINDING AFFINITIES; BINDING ASSAYS; BIOINFORMATIC ANALYSIS; BIOINFORMATIC MODELS; DATA-SETS; DISSOCIATION CONSTANTS; E. COLI; ELECTROPHORETIC MOBILITY SHIFT ASSAYS; ENERGY MATRICES; FUNCTIONAL SITES; IN-VITRO; IN-VIVO; PHYSICAL BINDINGS; PROTEIN-DNA INTERACTIONS; QUADRATIC PROGRAMMING METHODS; QUANTITATIVE ANALYSIS; S. TYPHIMURIUM; SEQUENCE SPECIFICITIES; SITE DETECTIONS; SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENTS; TRAINING DATASET; TRANSCRIPTION FACTOR BINDINGS; VARIABLE BINDINGS; WEIGHT MATRICES;

BINDING SITES;

BACTERIAL PROTEIN; CATABOLIC ACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; DNA;

ACCURACY; AMINO ACID SEQUENCE; ARTICLE; BACTERIAL GENOME; BINDING AFFINITY; BINDING SITE; BIOINFORMATICS; CONTROLLED STUDY; ESCHERICHIA COLI; GEL MOBILITY SHIFT ASSAY; IN VITRO STUDY; NONHUMAN; PREDICTION; PROTEIN DNA INTERACTION; QUANTITATIVE ANALYSIS; SALMONELLA TYPHIMURIUM; SEQUENCE ANALYSIS; SERIAL ANALYSIS OF GENE EXPRESSION; ALGORITHM; BIOLOGY; COMBINATORIAL CHEMISTRY; CONSENSUS SEQUENCE; DNA SEQUENCE; ENZYME SPECIFICITY; GENETICS; METABOLISM; METHODOLOGY; SENSITIVITY AND SPECIFICITY; STATISTICAL MODEL;

ALGORITHMS; BACTERIAL PROTEINS; BINDING SITES; COMPUTATIONAL BIOLOGY; CONSENSUS SEQUENCE; DNA; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ESCHERICHIA COLI; LIKELIHOOD FUNCTIONS; SELEX APTAMER TECHNIQUE; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS, DNA; SUBSTRATE SPECIFICITY; TRANSCRIPTION FACTORS;

EID: 62449175520     PISSN: None     EISSN: 14726750     Source Type: Journal    
DOI: 10.1186/1472-6750-8-94     Document Type: Article

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