Genetic analysis of Helicobacter pylori clinical isolates suggests resistance to metronidazole can occur without the loss of functional rdxA

Journal of Antibiotics

Volumn 62, Issue 1, 2009, Pages 43-50

  Kim, So Yeong ^a   Joo, Young Min ^a   Lee, Hak Sung ^b   Chung, In Sik ^b   Yoo, Yun Jung ^a   Merrell, D Scott ^c   Cha, Jeong Heon ^a,d  

^a Yonsei University College of Dentistry   (South Korea)

^b The Catholic University of Korea   (South Korea)

^c UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^d Yonsei University   (South Korea)

Author keywords

Antibiotic resistance; FrxA; Genetics; Helicobacter pylori; Metronidazole; RdxA

Indexed keywords

AMINO ACID; METRONIDAZOLE; NUCLEOTIDE;

ALLELE; AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATION; FRXA GENE; GENE EXPRESSION; GENE LOSS; GENETIC ANALYSIS; GENETIC VARIABILITY; HELICOBACTER PYLORI; MINIMUM INHIBITORY CONCENTRATION; MISSENSE MUTATION; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RDXA GENE;

ALLELES; BACTERIAL PROTEINS; DRUG RESISTANCE, BACTERIAL; HELICOBACTER PYLORI; METRONIDAZOLE; MICROBIAL SENSITIVITY TESTS; NITROREDUCTASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFORMATION, BACTERIAL;

HELICOBACTER PYLORI;

EID: 62449126513     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2008.6     Document Type: Article

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