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Volumn 28, Issue 6, 2008, Pages 430-437

Human Telomerase Reverse Transcriptase (hTERT): A target molecule for the treatment of cisplatin-resistant tumors

Author keywords

Apoptosis; Bladder cancer; Caspase; Cisplatin; hTERT

Indexed keywords

ANTINEOPLASTIC AGENT; BENZYLOXYCARBONYLVALYL ALANYL ASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYL-ALANYL-ASPARTYL FLUOROMETHYL KETONE; CASPASE; CISPLATIN; CYSTEINE PROTEINASE INHIBITOR; CYTOCHROME C; CYTOCHROME C''; PEPTIDE CHLOROMETHYL KETONE; PROTEIN BAX; SMALL INTERFERING RNA; TELOMERASE; TERT PROTEIN, HUMAN;

EID: 62349130927     PISSN: 15986535     EISSN: None     Source Type: Journal    
DOI: 10.3343/kjlm.2008.28.6.430     Document Type: Article
Times cited : (15)

References (35)
  • 1
    • 0028009789 scopus 로고
    • Cellular responses to cisplatin. The roles of DNA-binding proteins and DNA repair
    • Chu G. Cellular responses to cisplatin. The roles of DNA-binding proteins and DNA repair. J Biol Chem 1994;269:787-90.
    • (1994) J Biol Chem , vol.269 , pp. 787-790
    • Chu, G.1
  • 2
    • 0345256652 scopus 로고    scopus 로고
    • Cisplatin: Mode of cytotoxic action and molecular basis of resistance
    • DOI 10.1038/sj.onc.1206933, Drug Resistance
    • Siddik ZH. Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene 2003;22:7265-79. (Pubitemid 37487159)
    • (2003) Oncogene , vol.22 , Issue.47 REV. ISS. 6 , pp. 7265-7279
    • Siddik, Z.H.1
  • 3
    • 0028938652 scopus 로고
    • Advanced bladder cancer: The need to identify new agents in the post-M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) world
    • Roth BJ and Bajorin DF. Advanced bladder cancer: the need to identify new agents in the post-M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) world. J Urol 1995;153:894-900.
    • (1995) J Urol , vol.153 , pp. 894-900
    • Roth, B.J.1    Bajorin, D.F.2
  • 4
    • 0021335549 scopus 로고
    • High-dose cisplatin in hypertonic saline
    • Ozols RF, Corden BJ, Jacob J, Wesley MN, Ostchega Y, Young RC. High-dose cisplatin in hypertonic saline. Ann Intern Med 1984;100: 19-24. (Pubitemid 14219123)
    • (1984) Annals of Internal Medicine , vol.100 , Issue.1 , pp. 19-24
    • Ozols, R.F.1    Corden, B.J.2    Jacob, J.3
  • 5
    • 0033037410 scopus 로고    scopus 로고
    • Expression of p53 in cisplatin-resistant ovarian cancer cell lines: Modulation with the novel platinum analogue (1R, 2R- diaminocyclohexane)(trans- diacetato)(dichloro)platinum(IV)
    • Hagopian GS, Mills GB, Khokhar AR, Bast RC Jr, Siddik ZH. Expression of p53 in cisplatin-resistant ovarian cancer cell lines: modulation with the novel platinum analogue (1R, 2R-diaminocyclohexane)( trans-diacetato)(dichloro)- platinum(IV). Clin Cancer Res 1999; 5:655-63. (Pubitemid 29131977)
    • (1999) Clinical Cancer Research , vol.5 , Issue.3 , pp. 655-663
    • Hagopian, G.S.1    Mills, G.B.2    Khokhar, A.R.3    Bast Jr., R.C.4    Siddik, Z.H.5
  • 11
    • 0032522443 scopus 로고    scopus 로고
    • The telomerase reverse transcriptase: Components and regulation
    • Nugent CI and Lundblad V. The telomerase reverse transcriptase: components and regulation. Genes Dev 1998;12:1073-85. (Pubitemid 28194043)
    • (1998) Genes and Development , vol.12 , Issue.8 , pp. 1073-1085
    • Nugent, C.I.1    Lundblad, V.2
  • 13
    • 0037148273 scopus 로고    scopus 로고
    • Telomerase: Its clinical relevance in the diagnosis of bladder cancer
    • DOI 10.1038/sj/onc/1205071
    • Muller M. Telomerase: its clinical relevance in the diagnosis of bladder cancer. Oncogene 2002;21:650-5. (Pubitemid 34146267)
    • (2002) Oncogene , vol.21 , Issue.4 REV. ISS. 1 , pp. 650-655
    • Muller, M.1
  • 14
    • 0031885140 scopus 로고    scopus 로고
    • Non-radioactive measurement of telomerase activity in human bladder cancer, bladder washings, and in urine
    • DOI 10.1002/(SICI)1096-9896(199 801)184:1<71::AID-PA TH988>3.0.CO;2-#
    • Heine B, Hummel M, Muller M, Heicappell R, Miller K, Stein H. Non-radioactive measurement of telomerase activity in human bladder cancer, bladder washings, and in urine. J Pathol 1998;184:71-6. (Pubitemid 28086156)
    • (1998) Journal of Pathology , vol.184 , Issue.1 , pp. 71-76
    • Heine, B.1    Hummel, M.2    Muller, M.3    Heicappell, R.4    Miller, K.5    Stein, H.6
  • 15
    • 0031724318 scopus 로고    scopus 로고
    • Detection of human telomerase reverse transcriptase messenger RNA in voided urine samples as a useful diagnostic tool for bladder cancer
    • Ito H, Kyo S, Kanaya T, Takakura M, Koshida K, Namiki M, et al. Detection of human telomerase reverse transcriptase messenger RNA in voided urine samples as a useful diagnostic tool for bladder cancer. Clin Cancer Res 1998;4:2807-10. (Pubitemid 28523509)
    • (1998) Clinical Cancer Research , vol.4 , Issue.11 , pp. 2807-2810
    • Ito, H.1    Kyo, S.2    Kanaya, T.3    Takakura, M.4    Koshida, K.5    Namiki, M.6    Inoue, M.7
  • 16
    • 17444368073 scopus 로고    scopus 로고
    • Telomerase activity in urine sediments as a tool for noninvasive detection of bladder cancer
    • DOI 10.1016/j.canlet.2004.09.004
    • Dettlaff-Pokora A, Matuszewski M, Schlichtholz B. Telomerase activity in urine sediments as a tool for noninvasive detection of bladder cancer. Cancer Lett 2005;222:83-8. (Pubitemid 40544850)
    • (2005) Cancer Letters , vol.222 , Issue.1 , pp. 83-88
    • Dettlaff-Pokora, A.1    Matuszewski, M.2    Schlichtholz, B.3
  • 17
    • 0033822365 scopus 로고    scopus 로고
    • Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation
    • Wong KK, Chang S, Weiler SR, Ganesan S, Chaudhuri J, Zhu C, et al. Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation. Nat Genet 2000;26:85-8.
    • (2000) Nat Genet , vol.26 , pp. 85-88
    • Wong, K.K.1    Chang, S.2    Weiler, S.R.3    Ganesan, S.4    Chaudhuri, J.5    Zhu, C.6
  • 18
    • 0141842659 scopus 로고    scopus 로고
    • Consequences of telomerase inhibition and combination treatments for the proliferation of cancer cells
    • Chen Z, Koeneman KS, Corey DR. Consequences of telomerase inhibition and combination treatments for the proliferation of cancer cells. Cancer Res 2003;63:5917-25. (Pubitemid 37187493)
    • (2003) Cancer Research , vol.63 , Issue.18 , pp. 5917-5925
    • Chen, Z.1    Koeneman, K.S.2    Corey, D.R.3
  • 20
    • 23944516595 scopus 로고    scopus 로고
    • Pharmacological telomerase inhibition can sensitize drug-resistant and drug-sensitive cells to chemotherapeutic treatment
    • DOI 10.1124/mol.105.011494
    • Ward RJ and Autexier C. Pharmacological telomerase inhibition can sensitize drug-resistant and drug-sensitive cells to chemotherapeutic treatment. Mol Pharmacol 2005;68:779-86. (Pubitemid 41206032)
    • (2005) Molecular Pharmacology , vol.68 , Issue.3 , pp. 779-786
    • Ward, R.J.1    Autexier, C.2
  • 21
    • 3042801710 scopus 로고    scopus 로고
    • Change of chemosensitivity and cellular characteristics of cisplatinum resistant human bladder cancer cells induced by long-term cisplatinum treatment
    • Lee ES, Min KJ, Kim SW, Lee HW, Cho KS, Kim KM, et al. Change of chemosensitivity and cellular characteristics of cisplatinum resistant human bladder cancer cells induced by long-term cisplatinum treatment. Korean J Urol 1998;39:305-10.
    • (1998) Korean J Urol , vol.39 , pp. 305-310
    • Lee, E.S.1    Min, K.J.2    Kim, S.W.3    Lee, H.W.4    Cho, K.S.5    Kim, K.M.6
  • 23
    • 33646499218 scopus 로고    scopus 로고
    • Upregulation of Bcl-2 is associated with cisplatin-resistance via inhibition of Bax translocation in human bladder cancer cells
    • Cho HJ, Kim JK, Kim KD, Yoon HK, Cho MY, Park YP, et al. Upregulation of Bcl-2 is associated with cisplatin-resistance via inhibition of Bax translocation in human bladder cancer cells. Cancer Lett 2006;237:56-66.
    • (2006) Cancer Lett , vol.237 , pp. 56-66
    • Cho, H.J.1    Kim, J.K.2    Kim, K.D.3    Yoon, H.K.4    Cho, M.Y.5    Park, Y.P.6
  • 24
    • 0031006856 scopus 로고    scopus 로고
    • Bcl-2 modulates telomerase activity
    • DOI 10.1074/jbc.272.22.14183
    • Mandal M and Kumar R. Bcl-2 modulates telomerase activity. J Biol Chem 1997;272:14183-7. (Pubitemid 27232827)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.22 , pp. 14183-14187
    • Mandal, M.1    Kumar, R.2
  • 25
    • 0043125481 scopus 로고    scopus 로고
    • Detection of human telomerase reverse transcriptase mRNA in urine of patients with bladder cancer: Evaluation of an emerging tumor marker
    • DOI 10.1016/S0090-4295(03)00254-1
    • Melissourgos N, Kastrinakis NG, Davilas I, Foukas P, Farmakis A, Lykourinas M. Detection of human telomerase reverse transcriptase mRNA in urine of patients with bladder cancer: evaluation of an emerging tumor marker. Urology 2003;62:362-7. (Pubitemid 36952107)
    • (2003) Urology , vol.62 , Issue.2 , pp. 362-367
    • Melissourgos, N.1    Kastrinakis, N.G.2    Davilas, I.3    Foukas, P.4    Farmakis, A.5    Lykourinas, M.6
  • 26
    • 33644844096 scopus 로고    scopus 로고
    • ShRNA-targeted hTERT suppress cell proliferation of bladder cancer by inhibiting telomerase activity
    • Zou L, Zhang P, Luo C, Tu Z. shRNA-targeted hTERT suppress cell proliferation of bladder cancer by inhibiting telomerase activity. Cancer Chemother Pharmacol 2006;57:328-34.
    • (2006) Cancer Chemother Pharmacol , vol.57 , pp. 328-334
    • Zou, L.1    Zhang, P.2    Luo, C.3    Tu, Z.4
  • 28
    • 0035283512 scopus 로고    scopus 로고
    • Telomerase inhibitors
    • DOI 10.1016/S0167-7799(00)01541-9, PII S0167779900015419
    • White LK, Wright WE, Shay JW. Telomerase inhibitors. Trends Biotechnol 2001;19:114-20. (Pubitemid 32155432)
    • (2001) Trends in Biotechnology , vol.19 , Issue.3 , pp. 114-120
    • White, L.K.1    Wright, W.E.2    Shay, J.W.3
  • 30
    • 0035409880 scopus 로고    scopus 로고
    • Human telomerase reverse transcriptase antisense treatment downregulates the viability of prostate cancer cells in vitro
    • Schindler A, Fiedler U, Meye A, Schmidt U, Fussel S, Pilarsky C, et al. Human telomerase reverse transcriptase antisense treatment downregulates the viability of prostate cancer cells in vitro. Int J Oncol 2001;19:25-30.
    • (2001) Int J Oncol , vol.19 , pp. 25-30
    • Schindler, A.1    Fiedler, U.2    Meye, A.3    Schmidt, U.4    Fussel, S.5    Pilarsky, C.6
  • 32
    • 0034720202 scopus 로고    scopus 로고
    • Treatment of prostate cancer in vitro and in who with 2-5A-anti-telomerase RNA component
    • Kondo Y, Koga S, Komata T, Kondo S. Treatment of prostate cancer in vitro and in vivo with 2-5A-anti-telomerase RNA component. Oncogene 2000;19:2205-11. (Pubitemid 30307186)
    • (2000) Oncogene , vol.19 , Issue.18 , pp. 2205-2211
    • Kondo, Y.1    Koga, S.2    Komata, T.3    Kondo, S.4
  • 33
    • 0035024256 scopus 로고    scopus 로고
    • Treatment of bladder cancer cells in vitro and in vivo with 2-5A antisense telomerase RNA
    • DOI 10.1038/sj.gt.3301449
    • Koga S, Kondo Y, Komata T, Kondo S. Treatment of bladder cancer cells in vitro and in vivo with 2-5A antisense telomerase RNA. Gene Ther 2001;8:654-8. (Pubitemid 32422061)
    • (2001) Gene Therapy , vol.8 , Issue.8 , pp. 654-658
    • Koga, S.1    Kondo, Y.2    Komata, T.3    Kondo, S.4
  • 34
    • 0034775290 scopus 로고    scopus 로고
    • Ribozyme-mediated telomerase inhibition induces immediate cell loss but not telomere shortening in ovarian cancer cells
    • DOI 10.1038/sj.cgt.7700383
    • Saretzki G, Ludwig A, von Zglinicki T, Runnebaum IB. Ribozymemediated telomerase inhibition induces immediate cell loss but not telomere shortening in ovarian cancer cells. Cancer Gene Ther 2001; 8:827-34. (Pubitemid 32983139)
    • (2001) Cancer Gene Therapy , vol.8 , Issue.10 , pp. 827-834
    • Saretzki, G.1    Ludwig, A.2    Von Zglinicki, T.3    Runnebaum, I.B.4
  • 35
    • 85047697807 scopus 로고    scopus 로고
    • TERT regulates cell survival independent of telomerase enzymatic activity
    • DOI 10.1038/sj/onc/1205419
    • Cao Y, Li H, Deb S, Liu JP. TERT regulates cell survival independent of telomerase enzymatic activity. Oncogene 2002;21:3130-8. (Pubitemid 34548084)
    • (2002) Oncogene , vol.21 , Issue.20 , pp. 3130-3138
    • Cao, Y.1    Li, H.2    Deb, S.3    Liu, J.-P.4


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