Detection of human telomerase reverse transcriptase messenger RNA in voided urine samples as a useful diagnostic tool for bladder cancer

Clinical Cancer Research

Volumn 4, Issue 11, 1998, Pages 2807-2810

  Ito, Hideaki ^a   Kyo, Satoru ^a   Kanaya, Taro ^a   Takakura, Masahiro ^a   Koshida, Kiyoshi ^a   Namiki, Mikio ^a   Inoue, Masaki ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; RNA DIRECTED DNA POLYMERASE; TELOMERASE;

ADULT; AGED; ARTICLE; BLADDER CANCER; CANCER SCREENING; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TELOMERE; URINALYSIS; URINE CYTOLOGY; URINE SEDIMENT;

AGED; AGED, 80 AND OVER; DNA-BINDING PROTEINS; ENZYME TESTS; EVALUATION STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; PROTEINS; REAGENT KITS, DIAGNOSTIC; RNA; RNA, MESSENGER; TELOMERASE; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL; URINARY BLADDER NEOPLASMS;

EID: 0031724318     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Blackburn, E. H. Structure and function of telomere. Nature (Lond.), 350: 569-573, 1991.
2. Allsopp, R. C., Vaziri, H., Patterson, C., Goldstain, S., Younglai, E. V., Futcher, A. B., Greider, C. W., and Harley, C. B. Telomere length predicts replicative capacity of human fibroblasts. Proc Natl. Acad. Sci. USA, 89: 10114-10118, 1992.
3. Greider, C. W., and Blackburn, E. H. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature (Lond.), 337: 331-337, 1989.
4. Yu, G. L., Bradley, J. D., Attardi, L. D., and Blackburn, E. H. In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs. Nature (Lond.), 344: 126-131, 1990.
5. Kim, N. W., Piatyszek, M. A., Prowse, K. R., Harley, C. B., West, M. D., Ho, P. L. C., Oviello, G. M., Wright, W. E., Weinrich, S. L., and Shay, J. W. Specific association of human telomerase activity with immortal cells and cancer. Science (Washington DC), 266: 2011-2015, 1994.
6. Hiyama, E., Gollahon, L., Kataoka, T., Kuroi, K., Yokoyama, T., Gazdar, A. F., Hiyama, K., Piatyszek, M. A., and Shay, J. W. Telomerase activity in human breast tumors. J. Natl. Cancer. Inst., 88: 116-122, 1996.
7. Kyo, S., Ueno, H., Kanaya, T., and Inoue, M. Telomerase activity in gynecological tumors. Clin. Cancer. Res., 2: 2023-2028, 1996.
8. Kyo, S., Kunimi, K., Uchibayashi, T., Namiki, M., and Inoue, M. Telomerase activity in human urothelial tumors. Am. J. Clin. Pathol., 5: 555-569, 1997.
9. Feng, J., Funk, W. D., Wang, S. S., Weinrich, A. A. A., Chiu, C. P., Adams, R. R., Chang, E., Allsopp, R. C., Yu, J., Le, S., West, M. D., Harey, C. B., Andrew, W. H., Greider, C. W., and Villeponteau, B. The RNA component of human telomerase. Science (Washington DC), 269: 1236-1241, 1995.
10. Harrington, L., McPhail, T., Mar, V., Zhou, W., Oulton, R., Amgen EST Program, Bass, M. B., Arruda, I., and Robinson, M. O. A mammalian telomerase-associated protein. Science (Washington DC), 275: 973-977, 1997.
11. Nakayama, J., Saito, M., Nakamura, H., Matsuura, A., and Ishikawa, F. TLP1: a gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family. Cell, 88: 875-884, 1997.
12. Blasco, M. A., Lee, H. W., Hande, M. P., Samper, E., Lansdorp, P. M., DePinho, R. A., and Greider, C. W. Telomere shortening and tumor formation by mouse cells lacking telomere RNA. Cell, 91: 25-34, 1997.
13. Meyerson, M., Counter, C. M., Eaton, E. N., Ellisen, L. W., Steiner, P., Caddle, S. D., Ziaugra, L., Beijersbergen, R. L., Davidoff, M. J., Liu, Q., Bacchetti, S., Haber, D. A., and Weinberg, R. A. HEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell, 90: 785-795, 1997.
14. Nakamura, T. M., Morin, G. B., Chapman, K. B., Weinrich, S. L., Andrews, W. H., Lingner, J., Harley, C. B., and Cech, T. R. Telomerase catalytic subunit homologs from fission yeast and human. Science (Washington DC), 277: 955-959, 1997.
15. Takakura, M., Kyo, S., Kanaya, T., Tanaka, M., and Inoue, M. Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer. Cancer Res., 55: 1558-1561, 1998.
16. Nakayama, J., Tahara, H., Tahara, E., Saito, M., Ito, K., Nakamura, H., Nakanishi, T., Tahara, E., Ide, T., and Ishikawa, F. Telomerase activation by hTRT in human normal fibroblast and hepatocellular carcinomas. Nat. Genet., 18: 65-68, 1998.
17. Weinrich, S. L., Pruzan, R., Ma, L., Ouellette, M., Tesmer, V. M., Holt, S. E., Bodnar, A. G., Lichtsteiner, S., Kim, N. W., Trager, J. B., Taylor, R. D., Carlos, R., Andrews, W. H., Wright, W. E., Shay, J. W., Harley, C. B., and Morin, G. B. Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT. Nat. Genet., 17: 498-502, 1997.
18. Ito, H., Kyo, S., Takakura, M., Kanaya, T., Inoue, M., and Namiki, M. Expression of human telomerase subunits and correlation with telomerase activity in urothelial cancer. Clin. Cancer Res., 4: 1603-1608, 1998.
19. Burchill, S. A., Bradbury, M. F., Pittman, K., Southgate, J., Smith, B., and Selby, P. Detection of epithelial cancer cells in peripheral blood by reverse transcriptase-polymerase chain reaction. Br. J. Cancer, 71: 278-281, 1995.
20. Klein, A., Zemer, R., Buchumensky, V., Klaper, R., and Nissenkorn, I. Expression of cytokeratin 20 in urinary cytology of patients with bladder carcinoma. Cancer (Phila.), 82: 349-354, 1998.
21. Kinoshita, H., Ogawa, O., Kakehi, Y., Mishina, M., Mitsumori, K., Itoh, N., Yamada, H., Terachi, T., and Yoshida, O. Detection of telomerase activity in exfoliated cells in urine from patients with bladder cancer. J. Natl. Cancer Inst., 89: 724-730, 1997.
22. Yoshida, K., Sugino, T., Tahara, H., Woodman, A., Bolodeoku, J., Nargund, V., Fellows, G., Goodison, S., Tahara, E., and Tarin, D. Telomerase activity in bladder carcinoma and its implication for non-invasive diagnosis by detection of exfoliated cancer cells in urine. Cancer (Phila.), 79: 362-369, 1997.
23. Kavaler, E., Landman, J., Chang, Y., Droller, M. J., and Liu, B. C-S. Detecting human bladder carcinoma cells in voided urine samples by assaying for the presence of telomerase activity. Cancer (Phila.), 82: 708-714, 1998.
24. Linn, J. F., Lango, M., Halachmi, S., Shoenberg, M. P., and Sidransky, D. Microsatellite analysis and telomerase activity in archived tissue and urine samples of bladder cancer patients. Int. J. Cancer, 74: 625-629, 1997.