Effects of 1,4-phenylenebis (methylene) selenocyanate, phenethyl isothiocyauate, indole-3-carbinol, and d-limonene individually and in combination on the tumorigenicity of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung

Anticancer Research

Volumn 16, Issue 5 A, 1996, Pages 2709-2712

  El Bayoumy, Karam ^a   Upadhyaya, Pramod ^a   Desai, Dhimant H ^a   Amin, Shantu ^a   Hoffmann, Dietrich ^a   Wynder, Ernst L ^a  

^a AMERICAN HEALTH FOUNDATION   (United States)

Author keywords

Chemoprevention; Lung tumors; Tobacco specific nitrosamines

Indexed keywords

3 INDOLEMETHANOL; 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; CYANIC ACID DERIVATIVE; ISOTHIOCYANIC ACID DERIVATIVE; LIMONENE; ORGANOSELENIUM DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INCIDENCE; CANCER INHIBITION; CANCER PREVENTION; CARCINOGENICITY; CONTROLLED STUDY; DRUG STRUCTURE; FEMALE; LUNG CANCER; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

ANIMALS; ANTICARCINOGENIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOGENS; CYCLOHEXENES; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; INDOLES; ISOTHIOCYANATES; LUNG NEOPLASMS; MICE; NEOPLASMS, EXPERIMENTAL; NITROSAMINES; ORGANOSELENIUM COMPOUNDS; TERPENES;

EID: 0029909080     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Wattenberg LW: Chemoprevention of cancer. Cancer Res 45: 1-8, 1985.
2. Boone CW, Kelloff GJ, and Malone WE: Identification of candidate cancer chemopreventive agents and their evaluation in animal models and human clinical trials: a review. Cancer Res 50: 2-9, 1990.
3. Hoffmann D, Brunnemann KD, Prokopczyk B, and Djordjevic MV: Tobacco-specific nitrosamines and areca-derived N-nitrosamines: chemistry, biochemistry, carcinogenicity, and relevance to humans. J Toxicol Environ Health 41: 1-52, 1994.
4. Castonguay A, Stoner GD, Schmitt HAY, and Hecht SS: Metabolism of tobacco-specific N-nitrosamines in cultured human tissues. Proc Natl Acad Sci USA 60: 6694-6697, 1983.
5. Hecht SS, and Hoffmann D: The relevance of tobacco-specific nitrosamines to human cancer. Cancer Surv 8: 273-294, 1989.
6. Wynder EL and Hoffmann D: Smoking and lung cancer. Scientific challenges and opportunities. Cancer Res 54: 5284-5295,1994.
7. Hecht SS, Morse MA, Eklind KI, and Chung F-L: A/J mouse lung tumorigenesis by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its inhibition by arylalkyl isothiocyanates. Exp. Lung Res 17: 501 -511, 1991.
8. Hecht SS, Morse MA, Amin SG, Stoner GD, Jordan KG, Choi C-I, and Chung F-L Rapid single dose model for lung tumor induction in A/J mice by 4-(methylnitrosamino)-1(3-pyridyl)-1-butanone and the effect of diet. Carcinogenesis 10, 1901-1904, 1989.
9. El-Bayoumy K, Upadhyaya P, Desai DH, Amin S, and Hecht SS: Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone tumorigenicity in mouse lung by the synthetic organoselenium compound, 1,4-phenylenebis(methylene)selenocyanate. Carcinogenesis 14: 1111-1113, 1993.
10. 6- methylguanine formation, and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung. Cancer Res 49: 2894-2897, 1989.
11. Morse MA, LaGreca SD, Amin SG, and Chung F-L: Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), and on the metabolism and disposition of NNK in A/J mice. Cancer Res 50: 2613-2617, 1990.
12. Wattenberg LW and Coccia JB: Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone Carcinogenesis in mice by D-limonene and citrus fruit oils. Carcinogenesis 12: 115-117, 1991.
13. El-Bayoumy K, Chae Y-H, Upadhyaya P, Meschter C, Cohen LA, and Reddy BS: (Selenium in chemoprevention of Carcinogenesis 11.) Inhibition of 7,12-dimethylbenz(a)anthracene-induced tumors and DNA adduct formation in the mammary glands of female Sprague-Dawley rats by the synthetic organoselenium compound 1,4-phenylenebis(methylene)selenocyanate. Cancer Res 52: 2402-2407, 1992.
14. Prokopczyk B, Cox JE, Upadhyaya P, Amin S, Desai D, Hoffmann D, and El-Bayoumy K: Effects of dietary 1,4-phenylenebis(methylene) selenocyanate on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation in lung and liver of A/J mice and F344 rats. Carcinogenesis, in press, 1996.
15. El-Bayoumy K, Upadhyaya P, Chae Y-H, Sohn O-S, Rao CV, Fiala E, and Reddy BS Chemoprevention of cancer by organoselenium compounds. J Cell Biochem (Suppl.) 22: 92-100, 1995.
16. Reddy BS, Rivenson A, Kulkarni N, Upadhyaya P, and El-Bayoumy K: (Selenium in Chemoprevention of carcinogenesis 14.) Chemoprevention of colon carcinogenesis by the synthetic organoselenium compound, 1,4-phenylenebis(methylene) selenocyanate. Cancer Res 52: 5635-5640, 1992.
17. Thompson HJ, Wilson A, Lu J, Singh M, Jiang C, Upadhyaya P, El-Bayoumy K, and Ip C Comparison of the effects of an organic and an inorganic form of selenium on a mammary carcinoma cell line. Carcinogenesis 15: 183-186, 1994.
18. Ronai Z, Traganos F, Darzynkiewicz Z, Tillotson JK, Conaway CC, Upadhyaya P, and El-Bayoumy K: Effects of organic and inorganic selenium compounds on rat mammary tumor cells. Int J Cancer 63: 428-434, 1995.
19. Foiles PG, Fujiki H, Suganuma M, Okabe S, Yatsunami J, Miglietta LM, Upadhyaya P, El-Bayoumy K, and Ronai Z: Inhibition of PKC and PKA by chemopreventive organoselenium compounds. Int J Oncol 7: 685-690, 1995.
20. Morse MA, Reinhardt JC, Amin SG, Hecht SS, Stoner GD, and Chung F-L: Effect of dietary aromatic isothiocyanates fed subsequent to the administration of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone on lung tumorigenicity in mice. Cancer Lett 49: 225-230, 1990.
21. Gould MN, Wacker WD, and Maltzman TH: Chemoprevention and Chemotherapy of Mammary Tumors by Monoterpenoids. In: Mutagens and Carcinogens in the Diet (Pariza MW, Felton JS, Aeschbacher H-U and Sato S, eds). Wiley-Liss, 1990, New York, Chichester-Brisbane-Toronto-Singapore, pp 255-268.
22. Maltzman TH, Christou M, Gould MN, and Jefcoate CR: Effects of monoterpenoids on in vivo DMBA-DNA adduct formation and on phase I hepatic metabolizing enzymes. Carcinogenesis 12: 2081-2087, 1991.
23. Elegbede JA, Maltzman TH, Elson CE, and Gould MN: Effects of anticarcinogenic monoterpenes on phase II hepatic metabolizing enzymes. Carcinogenesis 14: 1221-1223, 1993.
24. Crowell PL, Chang RR, Ren Z, Elson CE, and Gould MN: Selective inhibition of isoprenylation of 21-26-kDa proteins by the anticarcinogen d-limonene and its metabolites. J Biol Chem 266: 17679-17685, 1991.
25. El-Bayoumy K: Evaluation of chemopreventive agents against breast cancer and proposed strategies for future clinical intervention trials. Carcinogenesis 15: 2395-2420, 1994.
26. McCormick DL, May CM, Thomas CF, and Detrisac CJ: Anticarcinogenic and hepatotoxic interactions between retinyl acetate and butylated hydroxytoluene in rats. Cancer Res 46: 5264-5269, 1986.