Geissospermum vellosii stembark. Anticholinesterase activity and improvement of scopolamine-induced memory deficits

Pharmacology Biochemistry and Behavior

Volumn 92, Issue 3, 2009, Pages 508-513

  Lima, Josélia A ^a   Costa, Rodrigo Saar ^a   Epifânio, Rosangela A ^b   Castro, Newton G ^a   Rocha, Mônica S ^a   Pinto, Angelo C ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

Author keywords

Acetylcholinesterase; Alzheimer; Butyrylcholinesterase; Geissospermum; Learning; Pao pereira; Passive avoidance; Scopolamine; Water maze

Indexed keywords

ACETYLCHOLINESTERASE; ALKALOID DERIVATIVE; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; GEISSOSPERMINE; GEISSOSPERMUM VELLOSII EXTRACT; PLANT EXTRACT; SCOPOLAMINE; UNCLASSIFIED DRUG;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOCYNACEAE; ARTICLE; BARK; CHOLINESTERASE INHIBITION; CONTROLLED STUDY; CONVULSION; GEISSOSPERMUM VELLOSII; LOCOMOTION; MALE; MAZE TEST; MEDICINAL PLANT; MOUSE; NONHUMAN; PASSIVE AVOIDANCE; PRIORITY JOURNAL; RAT; SPATIAL MEMORY;

ACETYLCHOLINESTERASE; ANIMALS; APOCYNACEAE; AVOIDANCE LEARNING; CHOLINESTERASE INHIBITORS; MALE; MAZE LEARNING; MEMORY DISORDERS; MICE; PLANT EXTRACTS; PLANT STEMS; SCOPOLAMINE;

ELECTROPHORUS ELECTRICUS; EQUIDAE; GEISSOSPERMUM; MUS; PEREIRA; RATTUS;

EID: 62249201254     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2009.01.024     Document Type: Article

References (42)

1. Adsersen A., Gauguin B., Gudiksen L., and Jäger A.K. Screening of plants used in Danish folk medicine to treat memory dysfunction for acetylcholinesterase inhibitory activity. J Ethnopharmacol 104 (2006) 418-422
2. Andrade M.T., Lima J.A., Pinto A.C., Rezende C.M., Carvalho M.P., and Epifanio R.A. Indole alkaloids from Tabernaemontana australis (Müell. Arg) Miers that inhibit acetylcholinesterase enzyme. Bioorg Med Chem 13 (2005) 4092-4095
3. Atack J.R., Yu Q.S., Soncrant T.T., Brossi A., and Rapoport S.I. Comparative inhibitory effects of various physostigmine analogs against acetyl- and butyrylcholinesterases. J Pharmacol Exp Ther 249 (1989) 194-202
4. Aurousseau M.M. Etude pharmacodynamique de la geissospermine. Alcaloïde principal du Geissospermum laeve (Vellozo) Baillon (Apocynacées). Ann Pharm Fr 19 (1961) 175-189
5. Aurousseau M.M. Etude comparée de quelques propriétés pharmacodynamiques de la geissospermine et de ses produits d'hydrolyse ou de reduction. Ann Pharm Fr 19 (1961) 515-519
6. Badia A., Banos J.E., Camps P., Contreras J., Gorbig D.M., Munoz-Torrero D., Simon M., and Vivas N.M. Synthesis and evaluation of tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease. Bioorg Med Chem 6 (1998) 427-440
7. Beljanski M. Flavopereirine-based pharmaceutical composition for treatment of HIV infection. Patent family written in French. PCT Int. Appl. (1994) 33pp.
8. Braida D., Paladini E., Griffini P., Lamperti M., Maggi A., and Sala M. An inverted U-shaped curve for heptylphysostigmine on radial maze performance in rats: comparison with other cholinesterase inhibitors. Eur J Pharmacol 302 (1996) 13-20
9. Camps P., Achab R.E., Morral J., Munöz-Torreno D., Badia A., Banos J.E., Vivas N.M., Barril X., Orozco M., and Luque F.J. New tacrine-huperzine A hybrids (huprines): highly potent tight-binding acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's disease. J Med Chem 43 (2000) 4657-4666
10. Cardoso C.L., Castro-Gamboa I., Silva D.H.S., Furlan M., Epifanio R.A., Pinto A.C., Rezende C.M., Lima J.A., and Bolzani V.S. Indole glucoalkaloids from Chimarrhis turbinata and their evaluation as antioxidant agents and acetylcholinesterase inhibitors. J Nat Prod 67 (2004) 1882-1885
11. Castro N.G., Costa R.S., Pimentel L.S., Danuello A., Romeiro N.C., Viegas Jr. C., et al. CNS-selective noncompetitive cholinesterase inhibitors derived from the natural piperidine alkaloid (-)-spectaline. Eur J Pharmacol 580 (2008) 339-349
12. Chattipakorn S., Pongpanparadorn A., Pratchayasakul W., Pongchaidacha A., Ingkaninan K., and Chattipakorn N. Tabernaemontana divaricata extract inhibits neuronal acetylcholinesterase activity in rats. J Ethnopharmacol 110 (2006) 61-68
13. Cumin R., Bandle E.F., Gamzu E., and Haefely W.E. Effects of the novel compound aniracetam (Ro 13-5057) upon impaired learning and memory in rodents. Psychopharmacol (Berl) 78 (1982) 104-111
14. dos Santos N.P., Pinto A.C., and Alencastro R.B. Theodoro Peckolt, farmacêutico do Brasil Imperial. Quim Nova 21 (1998) 666-670
15. Ellman G.L., Courtney K.D., Andres J.R.V., and Featherstone R.M. A new and rapid colorimetric determination of acetylcholinesterase. Biochem Pharmacol 07 (1961) 88-95
16. Fujimori H., and Cobb D. Central nervous system depressant activity of MA 1337, 3-[3,4-m-chlorophenyl-1-piperazyl propil-2-4 (1H, 3H) quinozolinedone hydrocholride. J Pharmacol Exp Ther 148 (1965) 151-157
17. Greig N.H., Lahiri D.K., and Sambamurti K. Butyrylcholinesterase: an important new target in Alzheimer's disease therapy. Int Psychogeriatr 14 Suppl 1 (2002) 77-91
18. 13C NMR analysis of geissospermine and its indole alkaloid monomer fragments. Tetrahedron Lett 19 14 (1978) 1235-1238
19. Houghton P.J., Ren Y., and Howes M.J. Acetylcholinesterase inhibitors from plants and fungi. Nat Prod Rep 23 (2006) 181-199
20. Ingkaninan K., Changwijit K., and Suwanborirux K. Vobasinyl-iboga bisindole alkaloids, potent acetylcholinesterase inhibitors from Tabernaemontana divaricata root. J Pharm Pharmacol 58 (2006) 847-852
21. Ingkaninan K., Temkitthawon P., Chuenchom K., Yuyaem T., and Thongnoi W. Screening for acetylcholinesterase inhibitory activity in plants used in Thai traditional rejuvenating and neurotonic remedies. J Ethnopharmacol 89 (2003) 261-264
22. Ingkaninan K., Yuyaem T., and Thongnoi W. Anticholinesterase activity in Stephania venosa Spreng. Naresuan Univ J 9 (2001) 35-40
23. Lleo A., Greenberg S.M., and Growdon J.H. Current pharmacotherapy for Alzheimer's disease. Annu Rev Med 57 (2006) 513-533
24. López S., Bastida J., Viladomat F., and Codina C. Acetylcholinesterase inhibitory activity of some Amaryllidaceae alkaloids and Narcissus extracts. Life Sci 71 (2002) 2521-2529
25. Mesulam M.M., Guillozet A., Shaw P., Levey A., Duysen E.G., and Lockridge O. Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine. Neuroscience 110 (2002) 627-639
26. Ogino T., Yamaguchi T., Sato T., Sasaki H., Sugama K., Okada M., and Maruno M. Studies of inhibitory activity against acetylcholinesterase of new bisbenzylisoquinoline alkaloid and its related compounds. Heterocycles 45 (1997) 2253-2260
27. Orhan I., Sener B., Chouhary M.I., and Khalid A. Acetylcholinesterase and butyrylcholinesterase inhibitory activity of some Turkish medicinal plants. J Ethnopharmacol 91 (2004) 57-60
28. Park C.H., Kim S., Choi W., Lee Y., Kim J., and Kang S.S. Novel anticholinesterase and antiamnesic activities of dehydroevodiamine, a constituent of Evodia rutaecarpa. Planta Med 62 (1996) 405-409
29. Pio Correa M. Diccionário de plantas úteis do Brasil e das exóticas cultivadas vol. IV (1984), Instituto Brasileiro de Desenvolvimento Florestal, Rio de Janeiro
30. Rapoport H., Onak T.P., Hughes N.A., and Reinecke M.G. Alkaloids of Geissospermum vellosii. J Am Chem Soc 80 (1958) 1601-1604
31. Rhee I.K., van de Meent M., Ingkaninan K., and Verpoorte R. Screening for acetylcholinesterase inhibitors from Amaryllidaceae using silica gel thin-layer chromatography in combination with bioactivity staining. J Chromatogr A 915 (2001) 217-223
32. Rhee I.K., van Rijn R.M., and Verpoorte R. Qualitative determination of false-positive effects in the acetylcholinesterase assay using thin layer chromatography. Phytochem Anal 14 (2003) 127-131
33. Peckolt G. As dez árvores genuinamente brasileiras mais úteis na medicina. Rev Flora Med 9 (1942) 453-470
34. Silver A. The biology of cholinesterases. North-Holland Research Monographs vol. 36 (1974), Elselvier, Amsterdam 426-447
35. Skolnick A.A. Old Chinese herbal medicine used for fever yields possible new Alzheimer disease therapy. JAMA 277 (1997) 776
36. Svensson A.L., Zhang X., and Nordberg A. Biphasic effect of tacrine on acetylcholine release in rat brain via M1 and M2 receptors. Brain Res 726 (1996) 207-212
37. Tanae M.M., Souccar C., Lapa A.J., and Lima-Landman M.T.R. Molecular interaction of Geissospermum's alkaloids with alpha 7 or muscle-type nicotinic receptors (nAChR) subtypes and with acetylcholinesterase (AChE). Acta Pharmacol Sin 27 Suppl. 1 (2006) 347-347
38. Terry Jr. A.V., and Buccafusco J.J. The cholinergic hypothesis of age and Alzheimer's disease-related cognitive deficits: recent challenges and their implications for novel drug development. J Pharmacol Exp Ther 306 (2003) 821-827
39. Trevisan M.T., and Macedo F.V.V. Seleção de plantas com atividade anticolinesterásica para tratamento da doença de Alzheimer. Quím Nova 26 (2003) 301-304
40. van Beek T.A., Verpoorte R., Baerheim S.A., Leeuwenberg A.J.M., Bisset N.G., and Tabernaemontana L. (Apocynaceae): a review of its taxonomy, phytochemistry, ethnobotany and pharmacology. J Ethnopharmacol 10 (1984) 1-156
41. Viegas Jr. C., Bolzani V.S., Pimentel L.S., Castro N.G., Cabral R.F., Costa R.S., Floyd C., Rocha M.S., Young M.C., Barreiro E.J., and Fraga C.A. New selective acetylcholinesterase inhibitors designed from natural piperidine alkaloids. Bioorg Med Chem 13 (2005) 4184-4190
42. Vigny M., Bon S., Massoulié J., and Leterrier F. Active-site catalytic efficiency of acetylcholinesterase molecular forms in Electrophorus, Torpedo, rat and chicken. Eur J Biochem 85 (1978) 317-323