Indole glucoalkaloids from Chimarrhis turbinata and their evaluation as antioxidant agents and acetylcholinesterase inhibitors

Journal of Natural Products

Volumn 67, Issue 11, 2004, Pages 1882-1885

  Cardoso, Carmem Lucia ^a   Castro Gamboa, Ian ^a   Siqueira Silva, Dulce Helena ^a   Furlan, Maysa ^a   Epifanio, Rosângela De A ^b   Da Cunha Pinto, Ângelo ^c   De Rezende, Cláudia Moraes ^c   Lima, Josélia Alencar ^c   Da Silva Bolzani, Vanderlan ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^c FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 3,4 DEHYDROSTRICTOSIDINE; 3,4 DEHYDROSTRICTOSIDINIC ACID; 5 ALPHA CARBOXYSTRICTOSIDINE; ANTIOXIDANT; CHOLINESTERASE INHIBITOR; CORDIFOLINE; DESOXYCORDIFOLINE; GALANTAMINE; HARMAN 3 CARBOXYLIC ACID; INDOLE ALKALOID; SCAVENGER; STRICTOSIDINE; STRICTOSIDINIC ACID; TURBINATINE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN; BRAZIL; CHIMARRHIS TURBINATA; DRUG DETERMINATION; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; ELECTROCHEMICAL DETECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; MEDICINAL PLANT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION REDUCTION REACTION; RAIN FOREST; STANDARD; THIN LAYER CHROMATOGRAPHY;

ANIMALS; ANTIOXIDANTS; BRAIN; BRAZIL; CHOLINESTERASE INHIBITORS; INDOLE ALKALOIDS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; RATS; RUBIACEAE;

CHIMARRHIS; CHIMARRHIS TURBINATA;

EID: 10044288231     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np049863m     Document Type: Article

References (14)

1. Baldach, A. A Flora Nacional na Medicina Doméstica; Imprensa Nacional: São Paulo, 1970; p 31.
2. Pinto, A. C.; Silva, D. H. S.; Bolzani, V. D.; Lopes, N. P.; Epifanio, R. Quim. Nova 2002, 25, 45-61.
3. Cardoso, C. L.; Silva, D. H. S.; Tomazela, D. M.; Young, M. C. M.; Eberlin, M. N.; Bolzani V. S. J. Nat. Prod. 2003, 66, 1017-1021.
4. Kyung, I. R.; van de Meent, M.; Ingkaninang, K.; Verpoorte, R. J. Chromatogr. A 2001, 915, 217-223.
5. Caprasse, M.; Coune, C.; Angenot, L. J. Pharm. Belg. 1983, 38, 135-139.
6. De Silva, K. T. D.; King, D.; Smith, G. N. Chem. Commun. 1971, 16, 908-909.
7. Brown, R. T.; Row, L. R. Chem. Commun. 1967, 9, 453-455.
8. Brandt, V.; Tits, M.; Geerlings, A.; Frérich, M.; Penelle, J.; Delaude, C.; Verpoorte, R.; Angenot, L. Phytochemistry 1999, 51, 1171-1176.
9. Sanchez, L. W. E.; Brown, K. S., Jr. An. Acad. Bras. Ciênc. 1971, 43, 603-605.
10. Castro-Gamboa, I.; Cardoso, C. L.; Silva, D. H. S.; Cavalheiro, A. J.; Furlan, M.; Bolzani, V. S. J. Braz. Chem. Soc. 2003, 14, 771-776.
11. Son, S.; Lewis, B. A. J. Agric. Food Chem. 2002, 50, 468-472.
12. Yamasaki, K.; Hashimoto, A.; Kokusenya, Y.; Miyamoto, T.; Sato, T. Chem. Pharm. Bull. 1994, 42, 1663-1665.
13. Fawcett, J. R.; Bordayo, E. Z.; Jackson, K.; Liu, H.; Peterson, J.; Svitak, A.; Frey, W. H. Brain Res. 2002, 950, 10-20.
14. Ellman, G. L.; Courtney, K. D.; Andres, V.; Featherstone, R. M. Biochem. Pharmacol. 1961, 7, 88-91.