메뉴 건너뛰기




Volumn 150, Issue 3, 2009, Pages 109-119

Characteristics of the main groups of human host-defensive peptides;Egyes humán gazdavédo peptidek jellegzetességei

Author keywords

Antimicrobial peptides; Cathelicidins; Defensins; Granulysins; Histatins; Host defensive peptides

Indexed keywords

ALPHA DEFENSIN; ANTIINFECTIVE AGENT; BETA DEFENSIN; CATHELICIDIN; DEFENSIN; GNLY PROTEIN, HUMAN; HISTATIN; T LYMPHOCYTE ANTIGEN;

EID: 62249106715     PISSN: 00306002     EISSN: 17886120     Source Type: Journal    
DOI: 10.1556/OH.2009.28512     Document Type: Article
Times cited : (3)

References (47)
  • 1
    • 29144521244 scopus 로고    scopus 로고
    • Human antimicrobial peptides: Defensins, cathelicidins and histatins
    • De Smet, K., Contreras, R.: Human antimicrobial peptides: defensins, cathelicidins and histatins. Biotechnol. Lett., 2005, 27, 1337-1347.
    • (2005) Biotechnol. Lett , vol.27 , pp. 1337-1347
    • De Smet, K.1    Contreras, R.2
  • 2
    • 0142218765 scopus 로고    scopus 로고
    • Oppenheim, J. J., Biragyn, A., Kwak, L. W. és mtsa: Roles of antimicrobial peptides such as defensins in innate and adaptive immunity. Ann. Rheum. Dis., 2003, 62 (Suppl) IIii17-ii21.
    • Oppenheim, J. J., Biragyn, A., Kwak, L. W. és mtsa: Roles of antimicrobial peptides such as defensins in innate and adaptive immunity. Ann. Rheum. Dis., 2003, 62 (Suppl) IIii17-ii21.
  • 3
    • 0033964867 scopus 로고    scopus 로고
    • Granulysin: A novel antimicrobial peptide of cytolytic T limphocytes and natural killer cells
    • Krensky, A. M.: Granulysin: a novel antimicrobial peptide of cytolytic T limphocytes and natural killer cells. Biochem. Pharmacol., 2000, 59, 317-320.
    • (2000) Biochem. Pharmacol , vol.59 , pp. 317-320
    • Krensky, A.M.1
  • 4
    • 9144261231 scopus 로고    scopus 로고
    • J. és mtsai: A genome wide screens identifi es a single β-defensin gene cluster on the chicken: implication for the origin and evolution of mammalian defensins
    • Doi: 10.1186/1471-2164-5-56;
    • Xiao, J., Hughes, A., L., Ando, J. és mtsai: A genome wide screens identifi es a single β-defensin gene cluster on the chicken: implication for the origin and evolution of mammalian defensins. BMC Genomics, 2004, 5, 56. Doi: 10.1186/1471-2164-5-56; http//www.biomedcentral.com/1471-2164/ 5//56
    • (2004) BMC Genomics , vol.5 , pp. 56
    • Xiao, J.1    Hughes, A.2    Ando, L.3
  • 5
    • 37349027564 scopus 로고    scopus 로고
    • Host-microbe interaction: Mechanisms of defensin defi ciency in Crohn's disease. Expert Rev. Anti. Infect
    • Wang, G., Stange, E. F., Wehkamp, J.: Host-microbe interaction: mechanisms of defensin defi ciency in Crohn's disease. Expert Rev. Anti. Infect. Ther., 2007, 5/6, 1049-1057.
    • (2007) Ther , vol.5-6 , pp. 1049-1057
    • Wang, G.1    Stange, E.F.2    Wehkamp, J.3
  • 6
    • 33845349605 scopus 로고    scopus 로고
    • Multispecific myeloid defensins
    • Lehrer, R. I.: Multispecific myeloid defensins. Curr. Opin. Hematol., 2007, 14, 16-21.
    • (2007) Curr. Opin. Hematol , vol.14 , pp. 16-21
    • Lehrer, R.I.1
  • 7
    • 33645393209 scopus 로고    scopus 로고
    • Chen, H., Xu, Z., Peng, L. A. és mtsai: Recent advances in the research and development of human defensins. Peptides, 2006, 27, 931-940.
    • Chen, H., Xu, Z., Peng, L. A. és mtsai: Recent advances in the research and development of human defensins. Peptides, 2006, 27, 931-940.
  • 8
    • 23844442574 scopus 로고    scopus 로고
    • Schneider, J. J., Unholzer, A., Schaller, M. és mtsai: Human defensins. J. Mol. Med., 2005, 83, 587-595.
    • Schneider, J. J., Unholzer, A., Schaller, M. és mtsai: Human defensins. J. Mol. Med., 2005, 83, 587-595.
  • 9
    • 4444246692 scopus 로고    scopus 로고
    • Primate defensins
    • Lehrer, R. I.: Primate defensins. Nat. Rev. Microbiol., 2004, 2, 727-738.
    • (2004) Nat. Rev. Microbiol , vol.2 , pp. 727-738
    • Lehrer, R.I.1
  • 10
    • 84873213015 scopus 로고    scopus 로고
    • Shures, A., Verma, C. H.: Modelling study of dimerization in mammalian defensins. BMC Bioinformatics, 2006, 7 (Suppl. 5) 517. Doi: 10,1186/1471.2105-7-55-517.
    • Shures, A., Verma, C. H.: Modelling study of dimerization in mammalian defensins. BMC Bioinformatics, 2006, 7 (Suppl. 5) 517. Doi: 10,1186/1471.2105-7-55-517.
  • 11
    • 0003438070 scopus 로고    scopus 로고
    • 6th edition, Mosby, Edinburgh, London, New York
    • Roitt, I., Brostoff, J., Male, D.: Immunology (6th edition). Mosby, Edinburgh, London, New York, 2001.
    • (2001) Immunology
    • Roitt, I.1    Brostoff, J.2    Male, D.3
  • 12
    • 0036884492 scopus 로고    scopus 로고
    • Gallo, R. L., Murakami, M., Ohtake, T. és mtsa: Biology and clinical relevance of naturally occurring antimicrobial peptides. J. Allergy Clin. Immunology, 2002, 110, 823-831.
    • Gallo, R. L., Murakami, M., Ohtake, T. és mtsa: Biology and clinical relevance of naturally occurring antimicrobial peptides. J. Allergy Clin. Immunology, 2002, 110, 823-831.
  • 13
    • 33748569152 scopus 로고    scopus 로고
    • Kim, Ch., Kaufmann, St., H. E.: Defensin: a multifunctional molecule lives up to its versatile name. Trend Microbiol., 2006, 14, 428-431.
    • Kim, Ch., Kaufmann, St., H. E.: Defensin: a multifunctional molecule lives up to its versatile name. Trend Microbiol., 2006, 14, 428-431.
  • 14
    • 0033044786 scopus 로고    scopus 로고
    • Antimicrobial peptides as mediators of epthelial host defence
    • Huttner, K. M., Bewins, Cl.: Antimicrobial peptides as mediators of epthelial host defence. Pediatr. Res., 1999, 45, 785-794
    • (1999) Pediatr. Res , vol.45 , pp. 785-794
    • Huttner, K.M.1    Bewins, C.2
  • 15
    • 22544488093 scopus 로고    scopus 로고
    • Events at the Host-Microbial Interface of the Gastrointestinal Tract V. Paneth cell α-defensins in intestinal host defense: Am
    • Bewins, Ch. L.: Events at the Host-Microbial Interface of the Gastrointestinal Tract V. Paneth cell α-defensins in intestinal host defense: Am. J. Physiol. Gastrointest. Liver Phys., 2005, 289, G173-G176.
    • (2005) J. Physiol. Gastrointest. Liver Phys , vol.289
    • Bewins, C.L.1
  • 16
    • 44149126798 scopus 로고    scopus 로고
    • Meyer-Hoffert, U., Hornef, M. W., Henriques-Normark, B. és mtsai: Secreted enteric antimicrobial activity localises to mucus surface layer. Gut, 2008, 57, 764-771.
    • Meyer-Hoffert, U., Hornef, M. W., Henriques-Normark, B. és mtsai: Secreted enteric antimicrobial activity localises to mucus surface layer. Gut, 2008, 57, 764-771.
  • 17
    • 0037057687 scopus 로고    scopus 로고
    • Zasloff, M.: Antimicrobial peptides in health and disease. New Engl. J. Med., 2002, 147, 1199-1200. (Editorial)
    • Zasloff, M.: Antimicrobial peptides in health and disease. New Engl. J. Med., 2002, 147, 1199-1200. (Editorial)
  • 18
    • 31944451136 scopus 로고    scopus 로고
    • Buck, C. B., Day, P. M., Thompson, C. D. és mtsai: Human alpha-defensins block papillomavirus infection. Proc. Natl. Acad. Sci., 2006, 103, 1516-1521.
    • Buck, C. B., Day, P. M., Thompson, C. D. és mtsai: Human alpha-defensins block papillomavirus infection. Proc. Natl. Acad. Sci., 2006, 103, 1516-1521.
  • 19
    • 38049030654 scopus 로고    scopus 로고
    • Smith, J. G., Nemerow, G. R.: Mechanism of adenovirus neutralization by human alpha-defensins. Cell Host Microbe, 2008, 3, 11-19.
    • Smith, J. G., Nemerow, G. R.: Mechanism of adenovirus neutralization by human alpha-defensins. Cell Host Microbe, 2008, 3, 11-19.
  • 20
    • 38049021057 scopus 로고    scopus 로고
    • Defensins' offensive play: Exploiting a viral achilles' heel
    • Buck, C. B.: Defensins' offensive play: exploiting a viral achilles' heel. Cell Host Microbe, 2008, 3, 3-4.
    • (2008) Cell Host Microbe , vol.3 , pp. 3-4
    • Buck, C.B.1
  • 21
    • 33749627000 scopus 로고    scopus 로고
    • Kübler, I., Stange, E. F., Fellermann, K. és mtsa: Defensine: körpereigene Antibiotika als zentraler Bestandteil des angeborenen Immunsystems. Dtsch. Med. Wochenschr., 2006, 31, 1960-1964. (Review)
    • Kübler, I., Stange, E. F., Fellermann, K. és mtsa: Defensine: körpereigene Antibiotika als zentraler Bestandteil des angeborenen Immunsystems. Dtsch. Med. Wochenschr., 2006, 31, 1960-1964. (Review)
  • 22
    • 33749006591 scopus 로고    scopus 로고
    • The human beta-defensin. 3, an antibacterial peptide with multiple biological functions
    • Dhople, V., Krukmeyer, A., Ramamoorthy, A.: The human beta-defensin. 3, an antibacterial peptide with multiple biological functions. Biochem. Biophys. Acta, 2006, 1758, 1499-1512.
    • (2006) Biochem. Biophys. Acta , vol.1758 , pp. 1499-1512
    • Dhople, V.1    Krukmeyer, A.2    Ramamoorthy, A.3
  • 23
    • 33745306114 scopus 로고    scopus 로고
    • Pazgier, M., Hoover, D. M., Yang, D. és mtsa: Human β-defensins. Cell. Mol. Life Sci., 2006, 63, 1294-1313. (Review)
    • Pazgier, M., Hoover, D. M., Yang, D. és mtsa: Human β-defensins. Cell. Mol. Life Sci., 2006, 63, 1294-1313. (Review)
  • 24
    • 77950217618 scopus 로고    scopus 로고
    • Huttner, K. M.: Antimicrobial peptides - The defence never rests. In: Neuroimmune biology. Szerk.: Berczi, I., Szentiványi, A. 5: Natural Immunity. Szerk.: Bertók, L., Chow, D. A. Elsevier, Amszterdam, 2005, 39-48.
    • Huttner, K. M.: Antimicrobial peptides - The defence never rests. In: Neuroimmune biology. Szerk.: Berczi, I., Szentiványi, A. Vol. 5: Natural Immunity. Szerk.: Bertók, L., Chow, D. A. Elsevier, Amszterdam, 2005, 39-48.
  • 25
    • 0037388020 scopus 로고    scopus 로고
    • Oren, A., Ganz, T., Liu, L. és mtsa: In human epidermis, β defensin 2 is packaged in lamellar bodies. Exp. Molec. Pathol., 2003, 74, 180-182.
    • Oren, A., Ganz, T., Liu, L. és mtsa: In human epidermis, β defensin 2 is packaged in lamellar bodies. Exp. Molec. Pathol., 2003, 74, 180-182.
  • 26
    • 23844442574 scopus 로고    scopus 로고
    • Schneider, J. J., Unholzer, A., Schaller, M. és mtsai: Human defensins. J. Mol. Med., 2005, 83, 587-595.
    • Schneider, J. J., Unholzer, A., Schaller, M. és mtsai: Human defensins. J. Mol. Med., 2005, 83, 587-595.
  • 27
    • 22244480342 scopus 로고    scopus 로고
    • Klüver, E., Schulz- Maronde, S., Scheid, S. és mtsa: Structure activity relation of human beta-defensin 3: infl uence of disulfi de bonds and cysteine substitution on antimicrobial activity and citotoxicity. Biochemistry, 2005, 44, 9804-9816.
    • Klüver, E., Schulz- Maronde, S., Scheid, S. és mtsa: Structure activity relation of human beta-defensin 3: infl uence of disulfi de bonds and cysteine substitution on antimicrobial activity and citotoxicity. Biochemistry, 2005, 44, 9804-9816.
  • 28
    • 42649142893 scopus 로고    scopus 로고
    • The role of the multifunctional peptide LL-37 in host defense
    • Kai-Larsen, Y., Agerberth, B.: The role of the multifunctional peptide LL-37 in host defense. Front Biosci., 2008, 13, 3760-3767.
    • (2008) Front Biosci , vol.13 , pp. 3760-3767
    • Kai-Larsen, Y.1    Agerberth, B.2
  • 29
    • 11144320719 scopus 로고    scopus 로고
    • J. és mtsai: Expression and secretion of cathelicidin antimicrobial peptides in murine mammary glands and human milk
    • Murakami, M., Dorschner, R. A., Stern, L. J. és mtsai: Expression and secretion of cathelicidin antimicrobial peptides in murine mammary glands and human milk. Pediatr. Res., 2005, 57, 10-15.
    • (2005) Pediatr. Res , vol.57 , pp. 10-15
    • Murakami, M.1    Dorschner, R.A.2    Stern, L.3
  • 30
    • 24644475283 scopus 로고    scopus 로고
    • Defensins and other antimicrobial peptides at the ocular surface
    • McDermott, A. M.: Defensins and other antimicrobial peptides at the ocular surface. Ocul. Surf., 2004, 2, 229-247.
    • (2004) Ocul. Surf , vol.2 , pp. 229-247
    • McDermott, A.M.1
  • 31
    • 33748935159 scopus 로고    scopus 로고
    • LL-37, the only human member of the cathelicidin family of antimicrobial peptides
    • Dürr, U. H. N., Sudheendra, U. S, Ramamoorthy, A.: LL-37, the only human member of the cathelicidin family of antimicrobial peptides. BBA. Biomembranes, 2006, 1758, 408-1425.
    • (2006) BBA. Biomembranes , vol.1758 , pp. 408-1425
    • Dürr, U.H.N.1    Sudheendra, U.S.2    Ramamoorthy, A.3
  • 32
    • 0842326097 scopus 로고    scopus 로고
    • Cathelicidins, multifunctional peptides of the innate immunity
    • Zanetti, M.: Cathelicidins, multifunctional peptides of the innate immunity. J. Leukocyt. Biol., 2004, 75, 39-48.
    • (2004) J. Leukocyt. Biol , vol.75 , pp. 39-48
    • Zanetti, M.1
  • 33
    • 33845682462 scopus 로고    scopus 로고
    • Motzkus, D., Schulz-Maronde, S., Heiland, A. és mtsai: The novel β-defensin DEFB123 prevents lipopolysaccharide-mediated effect in vitro and in vivo. Faseb J., 2006, 20, E997-E1004.
    • Motzkus, D., Schulz-Maronde, S., Heiland, A. és mtsai: The novel β-defensin DEFB123 prevents lipopolysaccharide-mediated effect in vitro and in vivo. Faseb J., 2006, 20, E997-E1004.
  • 34
    • 1642267482 scopus 로고    scopus 로고
    • Histatins: Antimicrobial peptides with therapeutic potential
    • Kavanagh, K., Dowd, S.: Histatins: antimicrobial peptides with therapeutic potential. J. Phar. Pharmacol., 2004, 56, 285-289.
    • (2004) J. Phar. Pharmacol , vol.56 , pp. 285-289
    • Kavanagh, K.1    Dowd, S.2
  • 35
    • 18244366046 scopus 로고    scopus 로고
    • Bowdish, D. M. E., Davidson, D. J., Scott, M. G. és mtsa: Im munomodulatory activities of small host defense peptides. Antimicrob. Agents Chemother., 2005, 49, 1727-1732.
    • Bowdish, D. M. E., Davidson, D. J., Scott, M. G. és mtsa: Im munomodulatory activities of small host defense peptides. Antimicrob. Agents Chemother., 2005, 49, 1727-1732.
  • 36
    • 13844315653 scopus 로고    scopus 로고
    • Bowdish, D. M. E., Davidson, D. J., Hancock, R. E. W.: A reevaluation of the role of host defence peptide in mammalian immunity. Curr. Protein Pept. Sci., 2005, 6, 35-51.
    • Bowdish, D. M. E., Davidson, D. J., Hancock, R. E. W.: A reevaluation of the role of host defence peptide in mammalian immunity. Curr. Protein Pept. Sci., 2005, 6, 35-51.
  • 37
    • 33847632044 scopus 로고    scopus 로고
    • Infl ammatory bowel disease: Past, present, and future
    • Review
    • Sands, B. E.: Infl ammatory bowel disease: past, present, and future. J. Gastroenterol., 2007, 42, 16-25. (Review)
    • (2007) J. Gastroenterol , vol.42 , pp. 16-25
    • Sands, B.E.1
  • 38
    • 34249945094 scopus 로고    scopus 로고
    • Defensins and other antimicrobial peptides in infl ammatory bowel disease
    • Wehkamp, J., Schmid, M., Stange, E. F.: Defensins and other antimicrobial peptides in infl ammatory bowel disease. Curr. Opin. Gastroenterol., 2007, 23, 370-378.
    • (2007) Curr. Opin. Gastroenterol , vol.23 , pp. 370-378
    • Wehkamp, J.1    Schmid, M.2    Stange, E.F.3
  • 39
    • 33645958888 scopus 로고    scopus 로고
    • Defensins and cathelicidins in infl ammatory lung disease: Beyond antimicrobial activity
    • Hiemstra, P. S.: Defensins and cathelicidins in infl ammatory lung disease: beyond antimicrobial activity. Biochem. Soc. Transactions, 2006, 34 (part 2), 276-278.
    • (2006) Biochem. Soc. Transactions , vol.34 , Issue.PART 2 , pp. 276-278
    • Hiemstra, P.S.1
  • 40
    • 33751007026 scopus 로고    scopus 로고
    • Aceti, A., Mangoni, M. L., Pasquazzi, C. és mtsai: Alpha-defensin increase in peripheral blood mononuclear cells from patients with hepatitis C virus chronic infection. J. Viral. Hepat., 2006, 13, 821-827.
    • Aceti, A., Mangoni, M. L., Pasquazzi, C. és mtsai: Alpha-defensin increase in peripheral blood mononuclear cells from patients with hepatitis C virus chronic infection. J. Viral. Hepat., 2006, 13, 821-827.
  • 41
    • 33748109943 scopus 로고    scopus 로고
    • Agerberth, B., Guömundsson, G. H.: Host antimicrobial defense peptides in human disease. CTMI, 2006, 306, 67-90. (Review) Springer Verlag, Berlin-Heidelberg, 2006.
    • Agerberth, B., Guömundsson, G. H.: Host antimicrobial defense peptides in human disease. CTMI, 2006, 306, 67-90. (Review) Springer Verlag, Berlin-Heidelberg, 2006.
  • 42
    • 27144520307 scopus 로고    scopus 로고
    • Wehkamp, J., Fellermann, K., Herrlinger, K. R. és mtsai: Mechanisms of disease: defensins in gastrointestinal diseases. Nat. Clin. Prac. Gastroenterol. Hepatol., 2005, 2, 406-415.
    • Wehkamp, J., Fellermann, K., Herrlinger, K. R. és mtsai: Mechanisms of disease: defensins in gastrointestinal diseases. Nat. Clin. Prac. Gastroenterol. Hepatol., 2005, 2, 406-415.
  • 43
    • 43849110585 scopus 로고    scopus 로고
    • Lakatos, P. L., Altorjay, I., Mándi Y. és mtsai: Interaction between seroreactivity to microbial antigens and genetics in Crohn's disease: is there a role for defensins? Tissue Antigens, 2008, 71, 552-559.
    • Lakatos, P. L., Altorjay, I., Mándi Y. és mtsai: Interaction between seroreactivity to microbial antigens and genetics in Crohn's disease: is there a role for defensins? Tissue Antigens, 2008, 71, 552-559.
  • 44
    • 33847731867 scopus 로고    scopus 로고
    • Nervekar, N., Lakha, F., Critchley, Ho. és mtsai: Changes in vaginal morphology, steroid receptor and natural antimicrobial content following treatment with low dose mifepristone. Contraception, 2007, 75, 271-280.
    • Nervekar, N., Lakha, F., Critchley, Ho. és mtsai: Changes in vaginal morphology, steroid receptor and natural antimicrobial content following treatment with low dose mifepristone. Contraception, 2007, 75, 271-280.
  • 45
    • 0030720063 scopus 로고    scopus 로고
    • Simmanco, M., Boman, A., Mangoni, M. L. és mtsai: Effect of glucocorticoids on the synthesis of antimicrobial peptides in amphibian skin. FEBS Lett., 1997, 416, 273-275.
    • Simmanco, M., Boman, A., Mangoni, M. L. és mtsai: Effect of glucocorticoids on the synthesis of antimicrobial peptides in amphibian skin. FEBS Lett., 1997, 416, 273-275.
  • 46
    • 13844308074 scopus 로고    scopus 로고
    • Defensins - non-antibiotic use for vaccine development
    • Review
    • Biragyn, A.: Defensins - non-antibiotic use for vaccine development. Curr. Protein Pept. Sci., 2005, 6, 53-60. (Review)
    • (2005) Curr. Protein Pept. Sci , vol.6 , pp. 53-60
    • Biragyn, A.1
  • 47
    • 28444489291 scopus 로고    scopus 로고
    • Protective roles of the skin against infection: Implication of naturally occurring human antimicrobial agents β-defensins, cathelicidin LL-37 and lyspzyme
    • Review
    • Niyonsaba, Fr., Ogawa, H.: Protective roles of the skin against infection: Implication of naturally occurring human antimicrobial agents β-defensins, cathelicidin LL-37 and lyspzyme. J. Dermatol. Sci., 2005, 40, 157-168. (Review)
    • (2005) J. Dermatol. Sci , vol.40 , pp. 157-168
    • Niyonsaba, F.1    Ogawa, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.