Antitumour and antimalarial activity of artemisinin-acridine hybrids

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 7, 2009, Pages 2033-2037

  Jones, Michael ^a   Mercer, Amy E ^a   Stocks, Paul A ^d   La Pensée, Louise J I ^a   Cosstick, Rick ^a   Park, B Kevin ^a   Kennedy, Miriam E ^b,c   Piantanida, Ivo ^c   Ward, Stephen A ^d   Davies, Jill ^d   Bray, Patrick G ^d   Rawe, Sarah L ^b   Baird, Jonathan ^e   Charidza, Tafadzwa ^e   Janneh, Omar ^a,e   O'Neill, Paul M ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b DUBLIN INSTITUTE OF TECHNOLOGY   (Ireland)

^c RUDER BO KOVI INSTITUTE   (Croatia)

^d LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^e UNIVERSITY OF ULSTER   (United Kingdom)

Author keywords

Acridine; Anticancer; Antimalarial; Apoptosis; Artemisinin; Confocal microscopy; DNA

Indexed keywords

ACRIDINE; ARTEMETHER; ARTEMISININ; ARTEMISININ ACRIDINE; CHLOROQUINE; DIHYDROARTEMISININ; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL STRAIN HL 60; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SYNTHESIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; PLASMODIUM FALCIPARUM;

PLASMODIUM FALCIPARUM;

EID: 62149130062     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.02.028     Document Type: Article

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