Hybrid α-bromoacryloylamido chalcones. Design, synthesis and biological evaluation

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 7, 2009, Pages 2022-2028

  Romagnoli, Romeo ^a   Baraldi, Pier Giovanni ^a   Carrion, Maria Dora ^a   Cruz Lopez, Olga ^a   Cara, Carlota Lopez ^a   Balzarini, Jan ^b   Hamel, Ernest ^c   Canella, Alessandro ^a   Fabbri, Enrica ^a   Gambari, Roberto ^a   Basso, Giuseppe ^d   Viola, Giampietro ^d  

^a UNIVERSITY OF FERRARA   (Italy)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c Developmental Therapeutics Program   (United States)

^d UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACRYLAMIDE DERIVATIVE; AMIDE; BROMINE DERIVATIVE; CASPASE 3; CHALCONE DERIVATIVE; KETONE DERIVATIVE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL STRAIN K 562; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYBRID; IC 50; MITOCHONDRION; MOUSE; NONHUMAN;

ANIMALS; ANTINEOPLASTIC AGENTS; CASPASE 3; CELL CYCLE; CELL LINE, TUMOR; CHALCONES; DRUG DESIGN; HUMANS; K562 CELLS; MICE; MITOCHONDRIA; REACTIVE OXYGEN SPECIES;

EID: 62149129314     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.02.038     Document Type: Article

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