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Volumn 4, Issue 2, 2008, Pages 59-64

The pathobiology of Krüppel-like factors in colorectal cancer

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EID: 62049086099     PISSN: 15563790     EISSN: 15563804     Source Type: Journal    
DOI: 10.1007/s11888-008-0011-4     Document Type: Review
Times cited : (48)

References (68)
  • 1
    • 33947313964 scopus 로고    scopus 로고
    • Atlanta: American Cancer Society; Accessed December 7, 2007
    • American Cancer Society: Cancer Facts & Figures 2007. Atlanta: American Cancer Society; 2007. Available at http://www.cancer.org/downloads/STT/ CAFF2007PWSecured. pdf. Accessed December 7, 2007.
    • (2007) American Cancer Society: Cancer Facts & Figures 2007
  • 2
    • 34247894942 scopus 로고    scopus 로고
    • Molecular genetics of colorectal cancer: An overview
    • Hisamuddin IM, Yang VW: Molecular genetics of colorectal cancer: An overview. Curr Colorectal Cancer Rep 2006, 2:53-59.
    • (2006) Curr Colorectal Cancer Rep , vol.2 , pp. 53-59
    • Hisamuddin, I.M.1    Yang, V.W.2
  • 3
    • 37949049850 scopus 로고
    • The evolution of cancer of the colon and rectum
    • Muto T, Bussey HJ, Morson BC: The evolution of cancer of the colon and rectum. Cancer 1975, 36:2251-2270.
    • (1975) Cancer , vol.36 , pp. 2251-2270
    • Muto, T.1    Bussey, H.J.2    Morson, B.C.3
  • 4
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B: A genetic model for colorectal tumorigenesis. Cell 1990, 61:759-767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 5
    • 36248962105 scopus 로고    scopus 로고
    • The genomic landscapes of human breast and colorectal cancers
    • Wood LD, Parsons DW, Jones S, et al.: The genomic landscapes of human breast and colorectal cancers. Science 2007, 318:1108-1113.
    • (2007) Science , vol.318 , pp. 1108-1113
    • Wood, L.D.1    Parsons, D.W.2    Jones, S.3
  • 6
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein B, Kinzler KW: Cancer genes and the pathways they control. Nat Med 2004, 10:789-799.
    • (2004) Nat Med , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 7
    • 0023057732 scopus 로고
    • A conserved family of nuclear proteins containing structural elements of the fnger protein encoded by Krüppel, a Drosophila segmentation gene
    • Schuh R, Aicher W, Gaul U, et al.: A conserved family of nuclear proteins containing structural elements of the fnger protein encoded by Krüppel, a Drosophila segmentation gene. Cell 1986, 47:1025-1032.
    • (1986) Cell , vol.47 , pp. 1025-1032
    • Schuh, R.1    Aicher, W.2    Gaul, U.3
  • 8
    • 0035860820 scopus 로고    scopus 로고
    • Krüppel-like factors: Three fngers in many pies
    • Bieker JJ: Krüppel-like factors: three fngers in many pies. J Biol Chem 2001, 276:34355-34358.
    • (2001) J Biol Chem , vol.276 , pp. 34355-34358
    • Bieker, J.J.1
  • 9
    • 0034929708 scopus 로고    scopus 로고
    • Sp1 and Krüppel-like factor family of transcription factors in cell growth regulation and cancer
    • Black AR, Black JD, Azizkhan-Clifford J: Sp1 and Krüppel-like factor family of transcription factors in cell growth regulation and cancer. J Cell Physiol 2001, 188:143-160.
    • (2001) J Cell Physiol , vol.188 , pp. 143-160
    • Black, A.R.1    Black, J.D.2    Azizkhan-Clifford, J.3
  • 10
    • 0034532675 scopus 로고    scopus 로고
    • The biology of the mammalian Krüppel-like family of transcription factors
    • Dang DT, Pevsner J, Yang VW: The biology of the mammalian Krüppel-like family of transcription factors. Int J Biochem Cell Biol 2000, 32:1103-1121.
    • (2000) Int J Biochem Cell Biol , vol.32 , pp. 1103-1121
    • Dang, D.T.1    Pevsner, J.2    Yang, V.W.3
  • 11
    • 0037218919 scopus 로고    scopus 로고
    • Sp1-and Krüppel-like transcription factors
    • Kaczynski J, Cook T, Urrutia R: Sp1-and Krüppel-like transcription factors. Genome Biol 2003, 4:206.
    • (2003) Genome Biol , vol.4 , pp. 206
    • Kaczynski, J.1    Cook, T.2    Urrutia, R.3
  • 12
    • 18944372399 scopus 로고    scopus 로고
    • Krüppel-like factors 4 and 5: The yin and yang regulators of cellular proliferation
    • Ghaleb AM, Nandan MO, Chanchevalap S, et al.: Krüppel-like factors 4 and 5: the yin and yang regulators of cellular proliferation. Cell Res 2005, 15:92-96.
    • (2005) Cell Res , vol.15 , pp. 92-96
    • Ghaleb, A.M.1    Nandan, M.O.2    Chanchevalap, S.3
  • 13
    • 34250216304 scopus 로고    scopus 로고
    • The diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiology
    • McConnell BB, Ghaleb AM, Nandan MO, Yang VW: The diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiology. Bioessays 2007, 29:549-557.
    • (2007) Bioessays , vol.29 , pp. 549-557
    • McConnell, B.B.1    Ghaleb, A.M.2    Nandan, M.O.3    Yang, V.W.4
  • 14
    • 0037377699 scopus 로고    scopus 로고
    • Krüppel cripples prostate cancer: KLF6 progress and prospects
    • Narla G, Friedman SL, Martignetti JA: Krüppel cripples prostate cancer: KLF6 progress and prospects. Am J Pathol 2003, 162:1047-1052.
    • (2003) Am J Pathol , vol.162 , pp. 1047-1052
    • Narla, G.1    Friedman, S.L.2    Martignetti, J.A.3
  • 15
    • 33846269644 scopus 로고    scopus 로고
    • KLF8 transcription factor participates in oncogenic transformation
    • Wang X, Zhao J: KLF8 transcription factor participates in oncogenic transformation. Oncogene 2007, 26:456-461.
    • (2007) Oncogene , vol.26 , pp. 456-461
    • Wang, X.1    Zhao, J.2
  • 16
    • 4143069155 scopus 로고    scopus 로고
    • KLF11 mediates a critical mechanism in TGF-beta signaling that is inactivated by Erk-MAPK in pancreatic cancer cells
    • Ellenrieder V, Buck A, Harth A, et al.: KLF11 mediates a critical mechanism in TGF-beta signaling that is inactivated by Erk-MAPK in pancreatic cancer cells. Gastroenterology 2004, 127:607-620.
    • (2004) Gastroenterology , vol.127 , pp. 607-620
    • Ellenrieder, V.1    Buck, A.2    Harth, A.3
  • 17
    • 0029829236 scopus 로고    scopus 로고
    • Identifcation and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest
    • Shields JM, Christy RJ, Yang VW: Identifcation and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest. J Biol Chem 1996, 271:20009-20017.
    • (1996) J Biol Chem , vol.271 , pp. 20009-20017
    • Shields, J.M.1    Christy, R.J.2    Yang, V.W.3
  • 18
    • 0030746063 scopus 로고    scopus 로고
    • Two potent nuclear localization signals in the gut-enriched Krüppel-like factor defne a subfamily of closely related Krüppel proteins
    • Shields JM, Yang VW: Two potent nuclear localization signals in the gut-enriched Krüppel-like factor defne a subfamily of closely related Krüppel proteins. J Biol Chem 1997, 272:1850 4-18507.
    • (1997) J Biol Chem , vol.272 , Issue.1850 , pp. 4-18507
    • Shields, J.M.1    Yang, V.W.2
  • 19
    • 0032004389 scopus 로고    scopus 로고
    • Identifcation of the DNA sequence that interacts with the gut-enriched Krüppel-like factor
    • Shields JM, Yang VW: Identifcation of the DNA sequence that interacts with the gut-enriched Krüppel-like factor. Nucleic Acids Res 1998, 26:796-802.
    • (1998) Nucleic Acids Res , vol.26 , pp. 796-802
    • Shields, J.M.1    Yang, V.W.2
  • 20
    • 0032503693 scopus 로고    scopus 로고
    • The gut-enriched Krüppel-like factor suppresses the activity of the CYP1A1 promoter in an Sp1-dependent fashion
    • Zhang W, Shields JM, Sogawa K, et al.: The gut-enriched Krüppel-like factor suppresses the activity of the CYP1A1 promoter in an Sp1-dependent fashion. J Biol Chem 1998, 273:17917-17925.
    • (1998) J Biol Chem , vol.273 , pp. 17917-17925
    • Zhang, W.1    Shields, J.M.2    Sogawa, K.3
  • 21
    • 0031451645 scopus 로고    scopus 로고
    • Expression of the gut-enriched Krüppel-like factor gene during development and intestinal tumorigenesis
    • Ton-That H, Kaestner KH, Shields JM, et al.: Expression of the gut-enriched Krüppel-like factor gene during development and intestinal tumorigenesis. FEBS Lett 1997, 419:239-243.
    • (1997) FEBS Lett , vol.419 , pp. 239-243
    • Ton-That, H.1    Kaestner, K.H.2    Shields, J.M.3
  • 22
    • 0035839554 scopus 로고    scopus 로고
    • Krüppel-like factor 4 (gut-enriched Krüppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle
    • Chen X, Johns DC, Geiman DE, et al.: Krüppel-like factor 4 (gut-enriched Krüppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle. J Biol Chem 2001, 276:30423-30428.
    • (2001) J Biol Chem , vol.276 , pp. 30423-30428
    • Chen, X.1    Johns, D.C.2    Geiman, D.E.3
  • 23
    • 0037462796 scopus 로고    scopus 로고
    • Krüppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage
    • Yoon HS, Chen X, Yang VW: Krüppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage. J Biol Chem 2003, 278:2101-2105.
    • (2003) J Biol Chem , vol.278 , pp. 2101-2105
    • Yoon, H.S.1    Chen, X.2    Yang, V.W.3
  • 24
    • 1042301369 scopus 로고    scopus 로고
    • Requirement of Krüppel-like factor 4 in preventing entry into mitosis following DNA damage
    • Yoon HS, Yang VW: Requirement of Krüppel-like factor 4 in preventing entry into mitosis following DNA damage. J Biol Chem 2004, 279:5035-5041.
    • (2004) J Biol Chem , vol.279 , pp. 5035-5041
    • Yoon, H.S.1    Yang, V.W.2
  • 25
    • 0034674712 scopus 로고    scopus 로고
    • The gut-enriched Krüppel-like factor (Krüppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/CIP1 promoter
    • Zhang W, Geiman DE, Shields JM, et al.: The gut-enriched Krüppel-like factor (Krüppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/CIP1 promoter. J Biol Chem 2000, 275:18391-18398.
    • (2000) J Biol Chem , vol.275 , pp. 18391-18398
    • Zhang, W.1    Geiman, D.E.2    Shields, J.M.3
  • 26
    • 0037459050 scopus 로고    scopus 로고
    • Transcriptional profling of Krüppel-like factor 4 reveals a function in cell cycle regulation and epithelial differentiation
    • Chen X, Whitney EM, Gao SY, Yang VW: Transcriptional profling of Krüppel-like factor 4 reveals a function in cell cycle regulation and epithelial differentiation. J Mol Biol 2003, 326:665-677.
    • (2003) J Mol Biol , vol.326 , pp. 665-677
    • Chen, X.1    Whitney, E.M.2    Gao, S.Y.3    Yang, V.W.4
  • 27
    • 0034617495 scopus 로고    scopus 로고
    • Decreased expression of the gut-enriched Krüppel-like factor gene in intestinal adenomas of multiple intestinal neoplasia mice and in colonic adenomas of familial adenomatous polyposis patients
    • Dang DT, Bachman KE, Mahatan CS, et al.: Decreased expression of the gut-enriched Krüppel-like factor gene in intestinal adenomas of multiple intestinal neoplasia mice and in colonic adenomas of familial adenomatous polyposis patients. FEBS Lett 2000, 476:203-207.
    • (2000) FEBS Lett , vol.476 , pp. 203-207
    • Dang, D.T.1    Bachman, K.E.2    Mahatan, C.S.3
  • 28
    • 0037780740 scopus 로고    scopus 로고
    • Overexpression of Krüppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenecity
    • Dang DT, Chen X, Feng J, et al.: Overexpression of Krüppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenecity. Oncogene 2003, 22:3424-3430.
    • (2003) Oncogene , vol.22 , pp. 3424-3430
    • Dang, D.T.1    Chen, X.2    Feng, J.3
  • 29
    • 0035833319 scopus 로고    scopus 로고
    • Expression of the gut-enriched Krüppel-like factor (Krüppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2
    • Dang DT, Mahatan CS, Dang LH, et al.: Expression of the gut-enriched Krüppel-like factor (Krüppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2. Oncogene 2001, 20:4884-4890.
    • (2001) Oncogene , vol.20 , pp. 4884-4890
    • Dang, D.T.1    Mahatan, C.S.2    Dang, L.H.3
  • 30
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers H: Wnt/beta-catenin signaling in development and disease. Cell 2006, 127:469-480.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 31
    • 0037163902 scopus 로고    scopus 로고
    • Gut-enriched Krüppel-like factor regulates colonic cell growth through APC/beta-catenin pathway
    • Stone CD, Chen ZY, Tseng CC: Gut-enriched Krüppel-like factor regulates colonic cell growth through APC/beta-catenin pathway. FEBS Lett 2002, 530:147-152.
    • (2002) FEBS Lett , vol.530 , pp. 147-152
    • Stone, C.D.1    Chen, Z.Y.2    Tseng, C.C.3
  • 32
    • 33644776032 scopus 로고    scopus 로고
    • Novel cross talk of Krüppel-like factor 4 and beta-catenin regulates normal intestinal homeostasis and tumor repression
    • Zhang W, Chen X, Kato Y, et al.: Novel cross talk of Krüppel-like factor 4 and beta-catenin regulates normal intestinal homeostasis and tumor repression. Mol Cell Biol 2006, 26:2055-2064.
    • (2006) Mol Cell Biol , vol.26 , pp. 2055-2064
    • Zhang, W.1    Chen, X.2    Kato, Y.3
  • 33
    • 34547642699 scopus 로고    scopus 로고
    • Haploinsuffciency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis
    • Ghaleb AM, McConnell BB, Nandan MO, et al.: Haploinsuffciency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis. Cancer Res 2007, 67:7147-7154.
    • (2007) Cancer Res , vol.67 , pp. 7147-7154
    • Ghaleb, A.M.1    McConnell, B.B.2    Nandan, M.O.3
  • 34
    • 0025015168 scopus 로고
    • A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
    • Moser AR, Pitot HC, Dove WF: A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 1990, 247:322-324.
    • (1990) Science , vol.247 , pp. 322-324
    • Moser, A.R.1    Pitot, H.C.2    Dove, W.F.3
  • 35
    • 0033680714 scopus 로고    scopus 로고
    • Role of gut-enriched Krüppel-like factor in colonic cell growth and differentiation
    • Shie JL, Chen ZY, O'Brien MJ, et al.: Role of gut-enriched Krüppel-like factor in colonic cell growth and differentiation. Am J Physiol Gastrointest Liver Physiol 2000, 279:G806-G814.
    • (2000) Am J Physiol Gastrointest Liver Physiol , vol.279
    • Shie, J.L.1    Chen, Z.Y.2    O'Brien, M.J.3
  • 36
    • 0842329848 scopus 로고    scopus 로고
    • Identifcation of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer
    • Zhao W, Hisamuddin IM, Nandan MO, et al.: Identifcation of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer. Oncogene 2004, 23:395-402.
    • (2004) Oncogene , vol.23 , pp. 395-402
    • Zhao, W.1    Hisamuddin, I.M.2    Nandan, M.O.3
  • 37
    • 21244499737 scopus 로고    scopus 로고
    • Krüppel-like factor 4 prevents centrosome amplifcation following gamma-irradiation-induced DNA damage
    • Yoon HS, Ghaleb AM, Nandan MO, et al.: Krüppel-like factor 4 prevents centrosome amplifcation following gamma-irradiation-induced DNA damage. Oncogene 2005, 24:4017-4025.
    • (2005) Oncogene , vol.24 , pp. 4017-4025
    • Yoon, H.S.1    Ghaleb, A.M.2    Nandan, M.O.3
  • 38
    • 0036340041 scopus 로고    scopus 로고
    • The zinc-fnger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon
    • Katz JP, Perreault N, Goldstein BG, et al.: The zinc-fnger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development 2002, 129:2619-2628.
    • (2002) Development , vol.129 , pp. 2619-2628
    • Katz, J.P.1    Perreault, N.2    Goldstein, B.G.3
  • 39
    • 20544460148 scopus 로고    scopus 로고
    • Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
    • van Es JH, van Gijn ME, Riccio O, et al.: Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 2005, 435:959-963.
    • (2005) Nature , vol.435 , pp. 959-963
    • Van Es, J.H.1    Van Gijn, M.E.2    Riccio, O.3
  • 40
    • 33847755702 scopus 로고    scopus 로고
    • WNT signaling in the normal intestine and colorectal cancer
    • de Lau W, Barker N, Clevers H: WNT signaling in the normal intestine and colorectal cancer. Front Biosci 2007, 12:471-491.
    • (2007) Front Biosci , vol.12 , pp. 471-491
    • De Lau, W.1    Barker, N.2    Clevers, H.3
  • 41
    • 0033104158 scopus 로고    scopus 로고
    • A gene encoding an intestinal-enriched member of the Krüppel-like factor family expressed in intestinal epithelial cells
    • Conkright MD, Wani MA, Anderson KP, Lingrel JB: A gene encoding an intestinal-enriched member of the Krüppel-like factor family expressed in intestinal epithelial cells. Nucleic Acids Res 1999, 27:1263-1270.
    • (1999) Nucleic Acids Res , vol.27 , pp. 1263-1270
    • Conkright, M.D.1    Wani, M.A.2    Anderson, K.P.3    Lingrel, J.B.4
  • 42
    • 0027299626 scopus 로고
    • CDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2
    • Sogawa K, Imataka H, Yamasaki Y, et al.: cDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2. Nucleic Acids Res 1993, 21:1527-1532.
    • (1993) Nucleic Acids Res , vol.21 , pp. 1527-1532
    • Sogawa, K.1    Imataka, H.2    Yamasaki, Y.3
  • 43
    • 0034031381 scopus 로고    scopus 로고
    • Developmental expression of the mouse gene coding for the Krüppel-like transcription factor KLF5
    • Ohnishi S, Laub F, Matsumoto N, et al.: Developmental expression of the mouse gene coding for the Krüppel-like transcription factor KLF5. Dev Dyn 2000, 217:421-429.
    • (2000) Dev Dyn , vol.217 , pp. 421-429
    • Ohnishi, S.1    Laub, F.2    Matsumoto, N.3
  • 44
    • 0036347210 scopus 로고    scopus 로고
    • Krüppel-like zinc-fnger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling
    • Shindo T, Manabe I, Fukushima Y, et al.: Krüppel-like zinc-fnger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling. Nat Med 2002, 8:856-863.
    • (2002) Nat Med , vol.8 , pp. 856-863
    • Shindo, T.1    Manabe, I.2    Fukushima, Y.3
  • 45
    • 0035831436 scopus 로고    scopus 로고
    • Intestinal-enriched Krüppel-like factor (Krüppel-like factor 5) is a positive regulator of cellular proliferation
    • Sun R, Chen X, Yang VW: Intestinal-enriched Krüppel-like factor (Krüppel-like factor 5) is a positive regulator of cellular proliferation. J Biol Chem 2001, 276:6897-6900.
    • (2001) J Biol Chem , vol.276 , pp. 6897-6900
    • Sun, R.1    Chen, X.2    Yang, V.W.3
  • 46
    • 9644277225 scopus 로고    scopus 로고
    • All-trans retinoic acid inhibits proliferation of intestinal epithelial cells by inhibiting expression of the gene encoding Krüppel-like factor 5
    • Chanchevalap S, Nandan MO, Merlin D, Yang VW: All-trans retinoic acid inhibits proliferation of intestinal epithelial cells by inhibiting expression of the gene encoding Krüppel-like factor 5. FEBS Lett 2004, 578:99-105.
    • (2004) FEBS Lett , vol.578 , pp. 99-105
    • Chanchevalap, S.1    Nandan, M.O.2    Merlin, D.3    Yang, V.W.4
  • 47
    • 34447522119 scopus 로고    scopus 로고
    • Lysophos-phatidic acid facilitates proliferation of colon cancer cells via induction of Krüppel-like factor 5
    • Zhang H, Bialkowska A, Rusovici R, et al.: Lysophos-phatidic acid facilitates proliferation of colon cancer cells via induction of Krüppel-like factor 5. J Biol Chem 2007, 282:15541-15549.
    • (2007) J Biol Chem , vol.282 , pp. 15541-15549
    • Zhang, H.1    Bialkowska, A.2    Rusovici, R.3
  • 48
    • 0035164288 scopus 로고    scopus 로고
    • Identifcation of a mouse homolog of the human BTEB2 transcription factor as a ß-catenin-independent Wnt-1-responsive gene
    • Ziemer LT, Pennica D, Levine AJ: Identifcation of a mouse homolog of the human BTEB2 transcription factor as a ß-catenin-independent Wnt-1-responsive gene. Mol Cell Biol 2001, 21:562-574.
    • (2001) Mol Cell Biol , vol.21 , pp. 562-574
    • Ziemer, L.T.1    Pennica, D.2    Levine, A.J.3
  • 49
    • 0037179848 scopus 로고    scopus 로고
    • A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer
    • Chen C, Bhalala HV, Qiao H, Dong JT: A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer. Oncogene 2002, 21:6567-6572.
    • (2002) Oncogene , vol.21 , pp. 6567-6572
    • Chen, C.1    Bhalala, H.V.2    Qiao, H.3    Dong, J.T.4
  • 50
    • 0037405689 scopus 로고    scopus 로고
    • KLF5 is frequently deleted and down-regulated but rarely mutated in prostate cancer
    • Chen C, Bhalala HV, Vessella RL, Dong JT KLF5 is frequently deleted and down-regulated but rarely mutated in prostate cancer. Prostate 2003, 55:81-88.
    • (2003) Prostate , vol.55 , pp. 81-88
    • Chen, C.1    Bhalala, H.V.2    Vessella, R.L.3    Dong, J.T.4
  • 51
    • 24044512379 scopus 로고    scopus 로고
    • Krüppel-like factor 5 promotes mitosis by activating the cyclin B1/Cdc2 complex during oncogenic Ras-mediated transformation
    • Nandan MO, Chanchevalap S, Dalton WB, Yang VW: Krüppel-like factor 5 promotes mitosis by activating the cyclin B1/Cdc2 complex during oncogenic Ras-mediated transformation. FEBS Lett 2005, 579:4757-4762.
    • (2005) FEBS Lett , vol.579 , pp. 4757-4762
    • Nandan, M.O.1    Chanchevalap, S.2    Dalton, W.B.3    Yang, V.W.4
  • 52
    • 2442686555 scopus 로고    scopus 로고
    • Krüppel-like factor 5 mediates the transforming activity of oncogenic H-Ras
    • Nandan MO, Yoon HS, Zhao W, et al.: Krüppel-like factor 5 mediates the transforming activity of oncogenic H-Ras. Oncogene 2004, 23:3404-3413.
    • (2004) Oncogene , vol.23 , pp. 3404-3413
    • Nandan, M.O.1    Yoon, H.S.2    Zhao, W.3
  • 53
    • 33947520145 scopus 로고    scopus 로고
    • Protein inhibitor of activated STAT1 interacts with and up-regulates activities of the pro-proliferative transcription factor Krüppel-like factor 5
    • Du JX, Yun CC, Bialkowska A, Yang VW: Protein inhibitor of activated STAT1 interacts with and up-regulates activities of the pro-proliferative transcription factor Krüppel-like factor 5. J Biol Chem 2007, 282:4782-4793.
    • (2007) J Biol Chem , vol.282 , pp. 4782-4793
    • Du, J.X.1    Yun, C.C.2    Bialkowska, A.3    Yang, V.W.4
  • 54
    • 1842425769 scopus 로고    scopus 로고
    • Intestinal tumor progression is associated with altered function of KLF5
    • Bateman NW, Tan D, Pestell RG, et al.: Intestinal tumor progression is associated with altered function of KLF5. J Biol Chem 2004, 279:12093-12101.
    • (2004) J Biol Chem , vol.279 , pp. 12093-12101
    • Bateman, N.W.1    Tan, D.2    Pestell, R.G.3
  • 55
    • 37349016202 scopus 로고    scopus 로고
    • Krüppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis
    • Nandan MO, McConnell BB, Ghaleb AM, et al.: Krüppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis. Gastroenterology 2008, 134:120-130.
    • (2008) Gastroenterology , vol.134 , pp. 120-130
    • Nandan, M.O.1    McConnell, B.B.2    Ghaleb, A.M.3
  • 56
    • 0023256456 scopus 로고
    • Prevalence of ras gene mutations in human colorectal cancers
    • Bos JL, Fearon ER, Hamilton SR, et al.: Prevalence of ras gene mutations in human colorectal cancers. Nature 1987, 327:293-297.
    • (1987) Nature , vol.327 , pp. 293-297
    • Bos, J.L.1    Fearon, E.R.2    Hamilton, S.R.3
  • 57
    • 0030960781 scopus 로고    scopus 로고
    • A novel human zinc fnger protein that interacts with the core promoter element of a TATA box-less gene
    • Koritschoner NP, Bocco JL, Panzetta-Dutari GM, et al.: A novel human zinc fnger protein that interacts with the core promoter element of a TATA box-less gene. J Biol Chem 1997, 272:9573-9580.
    • (1997) J Biol Chem , vol.272 , pp. 9573-9580
    • Koritschoner, N.P.1    Bocco, J.L.2    Panzetta-Dutari, G.M.3
  • 58
    • 0034603864 scopus 로고    scopus 로고
    • The Krüppel-like transcriptional factors Zf9 and GKLF coactivate the human keratin 4 promoter and physically interact
    • Okano J, Opitz OG, Nakagawa H, et al.: The Krüppel-like transcriptional factors Zf9 and GKLF coactivate the human keratin 4 promoter and physically interact. FEBS Lett 2000, 473:95-100.
    • (2000) FEBS Lett , vol.473 , pp. 95-100
    • Okano, J.1    Opitz, O.G.2    Nakagawa, H.3
  • 59
    • 18244389734 scopus 로고    scopus 로고
    • KLF6, a candidate tumor suppressor gene mutated in prostate cancer
    • Narla G, Heath KE, Reeves HL, et al.: KLF6, a candidate tumor suppressor gene mutated in prostate cancer. Science 2001, 294:2563-2566.
    • (2001) Science , vol.294 , pp. 2563-2566
    • Narla, G.1    Heath, K.E.2    Reeves, H.L.3
  • 60
    • 2542628097 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibition by the KLF6 tumor suppressor protein through interaction with cyclin D1
    • Benzeno S, Narla G, Allina J, et al.: Cyclin-dependent kinase inhibition by the KLF6 tumor suppressor protein through interaction with cyclin D1. Cancer Res 2004, 64:3885-3891.
    • (2004) Cancer Res , vol.64 , pp. 3885-3891
    • Benzeno, S.1    Narla, G.2    Allina, J.3
  • 61
    • 7044246221 scopus 로고    scopus 로고
    • Frequent inactivation of the tumor suppressor Krüppel-like factor 6 (KLF6) in hepatocellular carcinoma
    • Kremer-Tal S, Reeves HL, Narla G, et al.: Frequent inactivation of the tumor suppressor Krüppel-like factor 6 (KLF6) in hepatocellular carcinoma. Hepatology 2004, 40:1047-1052.
    • (2004) Hepatology , vol.40 , pp. 1047-1052
    • Kremer-Tal, S.1    Reeves, H.L.2    Narla, G.3
  • 62
    • 22744454819 scopus 로고    scopus 로고
    • Genetic alterations of the KLF6 gene in gastric cancer
    • Cho YG, Kim CJ, Park CH, et al.: Genetic alterations of the KLF6 gene in gastric cancer. Oncogene 2005, 24:4588-4590.
    • (2005) Oncogene , vol.24 , pp. 4588-4590
    • Cho, Y.G.1    Kim, C.J.2    Park, C.H.3
  • 63
    • 11144357280 scopus 로고    scopus 로고
    • Krüppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer
    • Reeves HL, Narla G, Ogunbiyi O, et al.: Krüppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer. Gastroenterology 2004, 126:1090-1103.
    • (2004) Gastroenterology , vol.126 , pp. 1090-1103
    • Reeves, H.L.1    Narla, G.2    Ogunbiyi, O.3
  • 64
    • 33745713651 scopus 로고    scopus 로고
    • Genetic alterations of the KLF6 gene in colorectal cancers
    • Cho YG, Choi BJ, Kim CJ, et al.: Genetic alterations of the KLF6 gene in colorectal cancers. APMIS 2006, 114: 458-464.
    • (2006) APMIS , vol.114 , pp. 458-464
    • Cho, Y.G.1    Choi, B.J.2    Kim, C.J.3
  • 65
    • 33646256805 scopus 로고    scopus 로고
    • Aberrant expression of Krüppel-like factor 6 protein in colorectal cancers
    • Cho YG, Choi BJ, Song JW, et al.: Aberrant expression of Krüppel-like factor 6 protein in colorectal cancers. World J Gastroenterol 2006, 12:2250-2253.
    • (2006) World J Gastroenterol , vol.12 , pp. 2250-2253
    • Cho, Y.G.1    Choi, B.J.2    Song, J.W.3
  • 66
    • 34547974859 scopus 로고    scopus 로고
    • Involvement of Krüppel-like factor 6 (KLF6) mutation in the development of nonpolypoid colorectal carcinoma
    • Mukai S, Hiyama T, Tanaka S, et al.: Involvement of Krüppel-like factor 6 (KLF6) mutation in the development of nonpolypoid colorectal carcinoma. World J Gastroen-terol 2007, 13:3932-3938.
    • (2007) World J Gastroen-terol , vol.13 , pp. 3932-3938
    • Mukai, S.1    Hiyama, T.2    Tanaka, S.3
  • 67
    • 34247115114 scopus 로고    scopus 로고
    • Difference in the role of loss of heterozygosity at 10p15 (KLF6 locus) in colorectal carcinogenesis between sporadic and familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer patients
    • Miyaki M, Yamaguchi T, Iijima T, et al.: Difference in the role of loss of heterozygosity at 10p15 (KLF6 locus) in colorectal carcinogenesis between sporadic and familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer patients. Oncology 2006, 71:131-135.
    • (2006) Oncology , vol.71 , pp. 131-135
    • Miyaki, M.1    Yamaguchi, T.2    Iijima, T.3
  • 68
    • 27944476041 scopus 로고    scopus 로고
    • Absence of mutation in the putative tumor-suppressor gene KLF6 in colorectal cancers
    • Lievre A, Landi B, Cote JF, et al.: Absence of mutation in the putative tumor-suppressor gene KLF6 in colorectal cancers. Oncogene 2005, 24:7253-7256.
    • (2005) Oncogene , vol.24 , pp. 7253-7256
    • Lievre, A.1    Landi, B.2    Cote, J.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.