Polymorphism in glutathione-S-transferases: A risk factor in alcoholic liver cirrhosis

Drug and Alcohol Dependence

Volumn 101, Issue 3, 2009, Pages 183-190

  Khan, Anwar Jamal ^a   Choudhuri, Gourdas ^b   Husain, Qayyum ^c   Parmar, Devendra ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^b SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

^c ALIGARH MUSLIM UNIVERSITY   (India)

Author keywords

Alcoholic liver cirrhosis; GST; Interaction; Polymorphism; Risk

Indexed keywords

CYTOCHROME P450 2E1; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; GLUTATHIONE TRANSFERASE T1; MANGANESE SUPEROXIDE DISMUTASE; REACTIVE OXYGEN METABOLITE;

ADULT; ALCOHOL LIVER CIRRHOSIS; ARTICLE; CONTROLLED STUDY; DETOXIFICATION; GENE; GENE FREQUENCY; GENE INTERACTION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; GSTM1 GENE; GSTP1 GENE; GSTT1 GENE; HUMAN; MAJOR CLINICAL STUDY; MALE; MNSOD GENE; PRIORITY JOURNAL; RISK ASSESSMENT;

ADULT; AGED; CASE-CONTROL STUDIES; DNA; GENE FREQUENCY; GLUTATHIONE S-TRANSFERASE PI; GLUTATHIONE TRANSFERASE; HUMANS; LIFE STYLE; LIVER CIRRHOSIS, ALCOHOLIC; MIDDLE AGED; POLYMORPHISM, GENETIC; RISK FACTORS;

EID: 61849182596     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2008.12.001     Document Type: Article

References (45)

1. Akyol O., Canatan H., Yilmaz H.R., Yuce H., Ozyurt H., Sogut S., Gulec M., and Elyas H. PCR/RFLP-based cost-effective identification of SOD2 signal (leader) sequence polymorphism (Ala-9Val) using NgoM IV: a detailed methodological approach. Clin. Chim. Acta 345 (July) 1-2 (2004) 151-159
2. Alves-Silva J., da Silva Santos M., GuimaraÄes P.E., Ferreira A.C., Bandelt H.J., Pena S.D., and Prado V.F. The ancestry of Brazilian mtDNA lineages. Am. J. Hum. Genet. 67 (2000) 444-461
3. Arand M., Muhlbauer R., Hengstler J., Jager E., Fuchs J., Winkler L., and Oesch F. A multiplex polymerase chain reaction for the simultaneous analysis of the glutathione S-transferase GSTM1 and GSTT1 polymorphisms. Anal. Biochem. 236 (1996) 184-186
4. Baranov V.S., Ivaschenko T., Bakay B., Aseev M., Belotserkovskaya R., Baranova H., Malet P., Perriot J., Mouraire P., Baskakov V.N., Savitskyi G.A., Gorbushin S., Deyneka S.I., Michnin E., Barchuck A., Vakharlovsky V., Pavlov G., Shilko V.I., Guembitzkaya T., and Kovaleva L. Proportion of the GSTM1 genotype in some Slavic populations and its correlation with cystic fibrosis and some multifactorial diseases. Hum. Genet. 97 (1996) 516-520
5. Borras E., Coutelle C., Rosell A., Fernández-Muixi F., Broch M., Crosas B., Hjelmqvist L., Lorenzo A., Gutiérrez C., Santos M., Szczepanek M., Heilig M., Quattrocchi P., Farrés J., Vidal F., Richart C., Mach T., Bogdal J., Jörnvall H., Seitz H.K., Couzigou P., and Parés X. Genetic polymorphism of alcohol dehydrogenase in Europeans: the ADH2*2 allele decreases the risk for alcoholism and is associated with ADH3*1. Hepatology 31 (2000) 984-989
6. Brind A.M., Hurlstone A., Edrisinghe D., Gilmore I., Fisher N., Pirmohamed M., and Fryer A.A. The role of polymorphisms of glutathione-S-transferases GSTM1, M3, P1, T1 and A1 in susceptibility to alcoholic liver disease. Alcohol Alcohol. 39 (2004) 478-483
7. Burim R.V., Canalle R., Martinelli Ade L., and Takahashi C.S. Polymorphisms in glutathione S-transferases GSTM1, GSTT1 and GSTP1 and cytochromes P4502E1 and CYP1A1 and susceptibility to cirrhosis or pancreatitis in alcoholics. Mutagenesis 19 (2004) 291-298
8. Choi J., and Ou J.-H.J. Mechanisms of liver injury. III. Oxidative stress in the pathogenesis of hepatitis C virus. Am. J. Physiol. Gastrointest. Liver Physiol. 290 (2006) G847-G851
9. Cichoz-Lach H., Partycka J., Nesina I., Celinski K., and Slomka M. The influence of genetic polymorphism of CYP2E1 on the development of alcohol liver cirrhosis. Wiad Lek. 59 (2006) 757-761
10. Degoul F., Sutton A., Mansouri A., Cepanec C., Degott C., Fromenty B., Beaugrand M., Valla D., and Pessayre D. Homozygosity for alanine in the mitochondrial targeting sequence of superoxide dismutase and risk for severe alcoholic liver disease. Gastroenterology 120 (2001) 1468-1474
11. Frenzer A., Butler W.J., Norton I.D., Wilson J.S., Apte M.V., Pirola R.C., Ryan P., and Roberts-Thomson I.C. Polymorphism in alcohol-metabolizing enzymes glutathione S-transferases and apolipoprotein E and susceptibility to alcohol-induced cirrhosis and chronic pancreatitis. J. Gastroenterol. Hepatol. 17 (2002) 177-182
12. Ghobadloo S.M., Yaghmaei B., Bakayev V., Goudarzi H., Noorinayer B., Rad F.H., Samiy S., Aghabozorghi S., and Zali M.R. GSTP1, GSTM1, and GSTT1 genetic polymorphisms in patients with cryptogenic liver cirrhosis. J. Gastrointest. Surg. 8 4 (2004) 423-427
13. Groppi A., Coutelle C., Fleury B., Iron A., Begueret J., and Couzigou P. Glutathione S-transferase class mu in French alcoholic cirrhostic patients. Hum. Genet. 87 (1991) 628-630
14. Grove J., Brown A.S., Daly A.K., Bassendine M.F., James O.F., and Day C.P. The RsaI polymorphism of CYP2E1 and susceptibility to alcoholic liver disease in Caucasians: effect on age of presentation and dependence on alcohol dehydrogenase genotype. Pharmacogenetics 8 (1998) 335-342
15. Harada S., Abei M., Tanaka N., Agarwal D.P., and Goedde H.W. Liver glutathione-S-transferase polymorphism in Japanese and its pharmacogenetic importance. Hum. Genet. 75 (1987) 322-325
16. Harada S., Takase S., Horiike N., Ishii K., Ishii N., and Takada A. Genetic and epidemiologic studies on alcoholic liver diseases. Arukoru Kenkyuto Yakubutsu Ison. 28 (1993) 400-413
17. Harries L.W., Stubbins M.J., Forman D., Howard G.C., and Wolf C.R. Identification of genetic polymorphisms at the glutathione S-transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer. Carcinogenesis 18 (1997) 641-644
18. Hrubec Z., and Omenn G.S. Evidence of genetic predisposition to alcoholic cirrhosis and psychosis: twin concodance for alcoholism and its biological end points by zygosity among male veterans. Alcohol: Clin. Exp. Res. 5 (1981) 207-215
19. Khan, A.J., Ruwali, M., Choudhuri C., Mathur, N., Husain, Q., Parmar, D., 2008. Polymorphism in Cytochrome P450 2E1 and interaction with other genetic risk factors and susceptibility to alcoholic liver cirrhosis. Mutat. Res., unpublished communication.
20. Ladero J.M., Martinez C., Garcia-Martin E., Fernández-Arquero M., López-Alonso G., and de la Concha E.G. Polymorphisms of the glutathione S-transferases mu-1 (GSTM1) and theta-1 (GSTT1) and the risk of advanced alcoholic liver disease. Scand. J. Gastroenterol. 40 (2005) 348-353
21. Li N., Oberley T.D., Oberley L.W., and Zhong W. Inhibition of cell growth in NIH/3T3 fibroblasts by overexpression of manganese superoxide dismutase: mechanistic studies. J. Cell Physiol. 175 (1998) 359-369
22. Lieber C.S. Microsomal ethanol-oxidizing system (MEOS): the first 30 years (1968-1998)-a review. Alcohol: Clin. Exp. Res. 23 6 (1999) 991-1007
23. Liu S., Park J.Y., Schantz S.P., Stern J.C., and Lazarus P. Elucidation of CYP2E1 5′ regulatory RsaI/PstI allelic variants and their role in risk for oral cancer. Oral oncol. 37 (2001) 437-445
24. Nahon P., Sutton A., Pessayre D., Rufat P., Degoul F., Ganne-Carrie N., Ziol M., Charnaux N., N'kontchou G., Trinchet J.C., Gattegno L., and Beaugrand M. Genetic dimorphism in superoxide dismutase and susceptibility to alcoholic cirrhosis, hepatocellular carcinoma, and death. Clin. Gastroenterol. Hepatol. 3 3 (2005) 292-298
25. Nelson H.H., Wiencke J.K., Christiani D.C., Cheng T.J., Zuo Z.F., Schwartz B.S., Lee B.K., Spitz M.R., Wang M., and Xu X. Ethnic differences in the prevalence of the homozygous deleted genotype of glutathione S transferase theta. Carcinogenesis 16 (1995) 1243-1245
26. Osman F.A., Akande O., Antoun G., Mao L.X., and Buolamwin J. Molecular cloning, characterization, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. evidence for different catalytic activity of the encoded proteins. J. Biol. Chem. 272 (1997) 10004-10012
27. Parl F.F. Glutathione S-transferase genotypes and cancer risk. Cancer Lett. 221 2 (2005) 123-129
28. Parola M., and Robino G. Oxidative stress-related molecules and liver fibrosis. J. Hepatol. 35 (2001) 297-306
29. Parsian A., Clonigner C.R., and Zhang Z.H. Association of polymorphisms of CYP2E1 gene in alcoholics with cirrhosis, antisocial personality, and normal controls. Alcohol: Clin. Exp. Res. 22 (1998) 888-891
30. Pemble S., Schroeder K.R., Spencer S.R., Meyer D.J., Hallier E., Bolt H.M., Ketterer B., and Taylor J.B. Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism. Biochem. J. 15 300 (1994) 271-276
31. Pirmohamed M., Kitteringham N.R., Quest L.J., Allott R.L., Green V.J., and Gilmore I.T. Genetic polymorphism of cytochrome P4502E1 and risk of alcoholic liver disease in Caucasians. Pharmacogenetics 5 (1995) 351-357
32. Rodrigo L., Alvarez V., Rodriguez M., Perez R., Alvarez R., and Coto E. N-Acetyltransferase-2, glutathione-S-transferase M1, alcohol dehydrogenase, and cytochrome P450IIE1 genotypes in alcoholic liver cirrhosis: a case-control study. Scand. J. Gastroenterol. 34 (1999) 303-307
33. Savolainen V.T., Pajarinen J., Perola M., Penttila A., and Karhunen P.J. Glutathione-S-transferase GSTM 'null' genotype and the risk of alcoholic liver disease. Alcohol: Clin. Exp. Res. 20 (1996) 1340-1345
34. Savolainen V.T., Pajarinen J., Perola M., Penttila A., and Karhunen P.J. Polymorphism in the cytochrome p4502E1 gene and risk of alcoholic liver disease. J. Hepatol. 26 (1997) 55-61
35. Seidegaard J., Pero R.W., and Stille B. Identification of the trans-stilbene oxide-active glutathione transferase in human mononuclear leukocytes and in liver as GST1. Biochem. Genet. 27 3-4 (1989) 253-261
36. Singh M., Shah P.P., Singh A.P., Ruwali M., Mathur N., Pant M.C., and Parmar D. Association of genetic polymorphisms in glutathione S-transferases and susceptibility to head and neck cancer. Mutat. Res. (2008) 184-194 1: 638(1-2)
37. Stickel F., and Osterreicher C.H. The role of genetic polymorphism in alcoholic liver disease. Alcohol Alcohol. 41 (2006) 209-224
38. Stickel F., Osterreicher C.H., Datz C., Ferenci P., Wölfel M., Norgauer W., Kraus M.R., Wrba F., Hellerbrand C., and Schuppan D. Prediction of progression to cirrhosis by a glutathione S-transferase P1 polymorphism in subjects with hereditary hemochromatosis. Arch. Intern. Med. 165 (2005) 1835-1840
39. Sutton A., Khoury H., Prip-Buus C., Cepanec C., Pessayre D., and Degoul F. The Ala16Val genetic dimorphism modulates the import of human manganese superoxide dismutase into rat liver mitochondria. Pharmacogenetics 13 (2003) 145-157
40. Takahashi T., Lasker J.M., Rosman A.S., and Lieber C.S. Induction of cytochrome P-4502E1 in the human liver by ethanol is caused by a corresponding increase in encoding messenger RNA. Hepatology 17 (1993) 236-245
41. Tanaka F., Shiratori Y., Yokosuka O., Imazeki F., Tsukada Y., and Omata M. Polymorphism of alcohol-metabolizing genes affects drinking behavior and alcoholic liver disease in Japanese men. Alcohol: Clin. Exp. Res. 21 (1997) 596-601
42. Tsutsumi M., Takada A., and Wang J.S. Genetic polymorphisms of cytochrome P4502E1 related to the development of alcoholic liver disease. Gastroenterology 107 (1994) 1430-1435
43. Vidal F., Lorenzo A., Auguet T., Olona M., Broch M., Gutierrez C., Aguilar C., Estupiñà P., Santos M., and Richart C. Genetic polymorphisms of ADH2, ADH3, CYP4502E1 Dra-I and Pst-I, and ALDH2 in Spanish men: lack of association with alcoholism and alcoholic liver disease. J. Hepatol. 41 (2004) 744-750
44. Watson M.A., Stewart R.K., Smith G.B., Massey T.E., and Bell D.A. Human glutathione S-transferase P1 polymorphisms: relationship to lung tissue enzyme activity and population frequency distribution. Carcinogenesis 19 (1998) 275-280
45. Wong N.A.C.S., Rae F., Simpson K.J., Murray G.D., and Harrison D.J. Genetic polymorphism of cytochrome P4502E1 and susceptibility to alcoholic liver disease and hepatocellular carcinoma in a white population: a study and literature review, including meta-analysis. J. Clin. Pathol./Mol. Pathol. 53 (2000) 88-93