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Volumn 21, Issue 4, 1997, Pages 596-601

Polymorphism of alcohol-metabolizing genes affects drinking behavior and alcoholic liver disease in Japanese men

Author keywords

Alcohol Dehydrogenase 2; Alcoholic Liver Disease; Aldehyde Dehydrogenase 2; Cytochrome P 450IIEI; Drinking Behavior

Indexed keywords

ALCOHOL; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; CYTOCHROME P450 ISOENZYME;

EID: 0030948774     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1997.tb03808.x     Document Type: Article
Times cited : (113)

References (44)
  • 1
    • 0014962167 scopus 로고
    • Hepatic microsomal ethanol oxidizing system: In vitro characteristics and adaptive properties in vivo
    • Lieber CS, DeCarli LM: Hepatic microsomal ethanol oxidizing system: In vitro characteristics and adaptive properties in vivo. J Biol Chem 245:2505-2512, 1970
    • (1970) J Biol Chem , vol.245 , pp. 2505-2512
    • Lieber, C.S.1    Decarli, L.M.2
  • 2
    • 0024244685 scopus 로고
    • Biochemical and molecular basis of alcohol-induced injury to liver and other tissues
    • Lieber CS: Biochemical and molecular basis of alcohol-induced injury to liver and other tissues. N Engl J Med 319:1639-1650, 1988
    • (1988) N Engl J Med , vol.319 , pp. 1639-1650
    • Lieber, C.S.1
  • 3
    • 0028350768 scopus 로고
    • Alcohol and the liver: 1994 update
    • Lieber CS: Alcohol and the liver: 1994 update, Gastroenterology 106:1085-1105, 1994
    • (1994) Gastroenterology , vol.106 , pp. 1085-1105
    • Lieber, C.S.1
  • 4
    • 0026062622 scopus 로고
    • Genetic polymorphisms in 5′-flanking region change transcriptional regulation of the human cytochrome P450IIEI gene
    • Hayashi SI, Watanbe J, Kawajiri K: Genetic polymorphisms in 5′-flanking region change transcriptional regulation of the human cytochrome P450IIEI gene. J Biochem 110:559-565, 1991
    • (1991) J Biochem , vol.110 , pp. 559-565
    • Hayashi, S.I.1    Watanbe, J.2    Kawajiri, K.3
  • 5
    • 0026567713 scopus 로고
    • Oxidative and reductive metabolism by cytochrome P450IIEL
    • Koop DR: Oxidative and reductive metabolism by cytochrome P450IIEL. FASAB J 6:724-730, 1992
    • (1992) FASAB J , vol.6 , pp. 724-730
    • Koop, D.R.1
  • 6
    • 0026697981 scopus 로고
    • Role of cytochrome P450 IIEI in ethanol-, carbon tetrachloride- and iron-dependent microsomal lipid peroxidation
    • Castillo T, Koop DR, Kamimura S, Triadafilopoul G, Tsukamoto H: Role of cytochrome P450 IIEI in ethanol-, carbon tetrachloride- and iron-dependent microsomal lipid peroxidation. Hepatology 16:992-996, 1992
    • (1992) Hepatology , vol.16 , pp. 992-996
    • Castillo, T.1    Koop, D.R.2    Kamimura, S.3    Triadafilopoul, G.4    Tsukamoto, H.5
  • 7
    • 0030045690 scopus 로고    scopus 로고
    • Role of cytochrome P450IIEI-dependent formation of hydroxyethyl free radical in the development of liver damage in rats intragastrically fed with ethanol
    • Albano E, Clot P, Morimoto M, Tomasi A, Ingelman-Sundberg M, French SW: Role of cytochrome P450IIEI-dependent formation of hydroxyethyl free radical in the development of liver damage in rats intragastrically fed with ethanol. Hepatology 23:155-163, 1996
    • (1996) Hepatology , vol.23 , pp. 155-163
    • Albano, E.1    Clot, P.2    Morimoto, M.3    Tomasi, A.4    Ingelman-Sundberg, M.5    French, S.W.6
  • 8
    • 0022543084 scopus 로고
    • Genetic polymorphism of human liver alcohol and aldehyde dehydrogenases, and their relationship to alcohol metabolism and alcoholism
    • Bosron W, Li TK: Genetic polymorphism of human liver alcohol and aldehyde dehydrogenases, and their relationship to alcohol metabolism and alcoholism. Hepatology 6:502-510, 1986
    • (1986) Hepatology , vol.6 , pp. 502-510
    • Bosron, W.1    Li, T.K.2
  • 9
    • 0027200395 scopus 로고
    • Genetic factors in alcohol metabolism and alcoholism
    • Bosron WF, Ehrig T, Li TK: Genetic factors in alcohol metabolism and alcoholism. Sem Liver Dis 13:126-135, 1993
    • (1993) Sem Liver Dis , vol.13 , pp. 126-135
    • Bosron, W.F.1    Ehrig, T.2    Li, T.K.3
  • 10
    • 0028934983 scopus 로고
    • Molecular biological aspects of alcohol-induced liver disease
    • Armon R, Esposti SD, Zern MA: Molecular biological aspects of alcohol-induced liver disease. Alcohol Clin Exp Res 19:247-256, 1995
    • (1995) Alcohol Clin Exp Res , vol.19 , pp. 247-256
    • Armon, R.1    Esposti, S.D.2    Zern, M.A.3
  • 11
    • 0027159741 scopus 로고
    • Alcohol and aldehyde dehydrogenase polymorphisms and alcoholism
    • Thomasson HR, Crabb DW, Edenberg HJ, Li TK: Alcohol and aldehyde dehydrogenase polymorphisms and alcoholism. Behav Genet 23:131-136, 1993
    • (1993) Behav Genet , vol.23 , pp. 131-136
    • Thomasson, H.R.1    Crabb, D.W.2    Edenberg, H.J.3    Li, T.K.4
  • 13
    • 0030063075 scopus 로고    scopus 로고
    • High incidence of ADH2*1/ALDH2*1 genes among Japanese alcohol dependents and patients with alcoholic liver disease
    • Tanaka F, Shiratori Y, Yokosuka O, Imazeki F, Tsukada Y, Omata M: High incidence of ADH2*1/ALDH2*1 genes among Japanese alcohol dependents and patients with alcoholic liver disease. Hepatology 23:234-239, 1996
    • (1996) Hepatology , vol.23 , pp. 234-239
    • Tanaka, F.1    Shiratori, Y.2    Yokosuka, O.3    Imazeki, F.4    Tsukada, Y.5    Omata, M.6
  • 15
    • 0011830097 scopus 로고
    • Molecular abnormality of an inactive aldehyde dehydrogenase variant commonly found in Orientals
    • Yoshida K, Huang IY, Ikawa M: Molecular abnormality of an inactive aldehyde dehydrogenase variant commonly found in Orientals. Proc Natl Acad Sci USA 81:258-261, 1984
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 258-261
    • Yoshida, K.1    Huang, I.Y.2    Ikawa, M.3
  • 16
    • 0024575209 scopus 로고
    • Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity
    • Crabb DW, Edenberg HJ, Bosron WF, Li TK: Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. J Clin Invest 83:314-316, 1989
    • (1989) J Clin Invest , vol.83 , pp. 314-316
    • Crabb, D.W.1    Edenberg, H.J.2    Bosron, W.F.3    Li, T.K.4
  • 17
    • 0029242884 scopus 로고
    • Alcohol and the mystique of flushing
    • Chao HM: Alcohol and the mystique of flushing. Alcohol Clin Exp Res 19:104-109, 1995
    • (1995) Alcohol Clin Exp Res , vol.19 , pp. 104-109
    • Chao, H.M.1
  • 18
    • 0024477613 scopus 로고
    • Genotypes of alcohol denydrogenase and aldehyde dehydrogenase loci in Japanese alcohol flushers and nonflushers
    • Shibuya A, Yasunami M, Yoshida A: Genotypes of alcohol denydrogenase and aldehyde dehydrogenase loci in Japanese alcohol flushers and nonflushers. Human Genet 82:14-16, 1989
    • (1989) Human Genet , vol.82 , pp. 14-16
    • Shibuya, A.1    Yasunami, M.2    Yoshida, A.3
  • 19
    • 0023757542 scopus 로고
    • Genotypes of alcohol-metabolizing enzymes in Japanese with alcohol liver diseases: A strong association of the usual Caucasian-type aldehyde dehydrogenase gene (ALDH2*1) with the disease
    • Shibuya A, Yoshida A: Genotypes of alcohol-metabolizing enzymes in Japanese with alcohol liver diseases: A strong association of the usual Caucasian-type aldehyde dehydrogenase gene (ALDH2*1) with the disease. Am J Hum Genet 43:744-748, 1988
    • (1988) Am J Hum Genet , vol.43 , pp. 744-748
    • Shibuya, A.1    Yoshida, A.2
  • 20
    • 0024446979 scopus 로고
    • Polymorphism of aldehyde dehydrogenase and its application to alcoholism
    • Harada S: Polymorphism of aldehyde dehydrogenase and its application to alcoholism. Electrophoresis 10:652-655, 1989
    • (1989) Electrophoresis , vol.10 , pp. 652-655
    • Harada, S.1
  • 21
    • 0028177496 scopus 로고
    • Polymorphism of alcohol and aldehyde dehydrogenase genes and alcohol cirrhosis in Chinese patients
    • Chao YC, Liou SR, Chung YY, Tang HS, Hsu CT, Li TK, Yin SJ: Polymorphism of alcohol and aldehyde dehydrogenase genes and alcohol cirrhosis in Chinese patients. Hepatology 19:360-366, 1994
    • (1994) Hepatology , vol.19 , pp. 360-366
    • Chao, Y.C.1    Liou, S.R.2    Chung, Y.Y.3    Tang, H.S.4    Hsu, C.T.5    Li, T.K.6    Yin, S.J.7
  • 22
    • 0021966860 scopus 로고
    • Aldehyde dehydrogenase polymorphism and alcohol metabolism in alcoholics
    • Harada S, Agarwal DP, Goedde HW: Aldehyde dehydrogenase polymorphism and alcohol metabolism in alcoholics. Alcohol 2:391-392, 1985
    • (1985) Alcohol , vol.2 , pp. 391-392
    • Harada, S.1    Agarwal, D.P.2    Goedde, H.W.3
  • 23
    • 0025947090 scopus 로고
    • Alcoholic liver disease in heterozygote of mutant and normal aldehyde dehydrogenase-2 genes
    • Enomoto N, Takase S, Takada N, Takada A: Alcoholic liver disease in heterozygote of mutant and normal aldehyde dehydrogenase-2 genes. Hepatology 13:1071-1075, 1981
    • (1981) Hepatology , vol.13 , pp. 1071-1075
    • Enomoto, N.1    Takase, S.2    Takada, N.3    Takada, A.4
  • 25
    • 0026034835 scopus 로고
    • Acetaldehyde metabolism in different aldehyde dehydrogenase-2 genotypes
    • Enomoto N, Takase S, Yasuhara M, Takada A: Acetaldehyde metabolism in different aldehyde dehydrogenase-2 genotypes. Alcohol Clin Exp Res 15:141-144, 1991
    • (1991) Alcohol Clin Exp Res , vol.15 , pp. 141-144
    • Enomoto, N.1    Takase, S.2    Yasuhara, M.3    Takada, A.4
  • 26
    • 0028048215 scopus 로고
    • Characterization of the three genotypes of low Km aldehyde dehydrogenase in a Japanese population
    • Takeshita T, Morimoto K, Mao XQ, Hashimoto T, Furuyama J: Characterization of the three genotypes of low Km aldehyde dehydrogenase in a Japanese population. Hum Genet 94:217-223, 1994
    • (1994) Hum Genet , vol.94 , pp. 217-223
    • Takeshita, T.1    Morimoto, K.2    Mao, X.Q.3    Hashimoto, T.4    Furuyama, J.5
  • 27
    • 0027943121 scopus 로고
    • Genetic polymorphisms of cytochrome P4502E1 related to the development of alcoholic liver disease
    • Tsutsumi M, Takada A, Wang JS: Genetic polymorphisms of cytochrome P4502E1 related to the development of alcoholic liver disease. Gastroenterology 107:1430-1435, 1994
    • (1994) Gastroenterology , vol.107 , pp. 1430-1435
    • Tsutsumi, M.1    Takada, A.2    Wang, J.S.3
  • 30
    • 0029122840 scopus 로고
    • Polymorphisms in alcohol metabolizing enzyme genes and alcohol cirrbosis in Japanese patients: A multivariate analysis
    • Yamauchi M, Maezawa Y, Mizuhara Y, Ohata M, Hirakawa J, Nakajima H. Toda G: Polymorphisms in alcohol metabolizing enzyme genes and alcohol cirrbosis in Japanese patients: A multivariate analysis. Hepatology 22:1136-1142, 1995
    • (1995) Hepatology , vol.22 , pp. 1136-1142
    • Yamauchi, M.1    Maezawa, Y.2    Mizuhara, Y.3    Ohata, M.4    Hirakawa, J.5    Nakajima, H.6    Toda, G.7
  • 31
    • 0028847431 scopus 로고
    • An Investi- Gation of whether polymorphisms of cytochrome P4502E1 are genetic markers of susceptibility to alcoholic end-stage organ damage in a Chinese population
    • Chao YC, Young TH, Chang WK, Tang HS. Hsu CT: An Investi- gation of whether polymorphisms of cytochrome P4502E1 are genetic markers of susceptibility to alcoholic end-stage organ damage in a Chinese population. Hepatology 22:1409-1414, 1995
    • (1995) Hepatology , vol.22 , pp. 1409-1414
    • Chao, Y.C.1    Young, T.H.2    Chang, W.K.3    Tang, H.S.4    Hsu, C.T.5
  • 32
    • 0019463397 scopus 로고
    • Alcoholic liver disease; Morphological manifestation
    • MacSween et al. (International Group): Alcoholic liver disease; Morphological manifestation. Lancet 1:707-711, 1981
    • (1981) Lancet , vol.1 , pp. 707-711
    • MacSween1
  • 34
    • 0027332014 scopus 로고
    • Improved methods for genotype determination at the ALDH2 locus using PCR by introducing the MboII recognition site or conducting secondary PCR
    • Nakamura K, Iwahashi K, Matsuo Y, Ichikawa Y: Improved methods for genotype determination at the ALDH2 locus using PCR by introducing the MboII recognition site or conducting secondary PCR. Biochem Mol Biol Int 31:439-445, 1993
    • (1993) Biochem Mol Biol int , vol.31 , pp. 439-445
    • Nakamura, K.1    Iwahashi, K.2    Matsuo, Y.3    Ichikawa, Y.4
  • 35
    • 0023990035 scopus 로고
    • Genotyping of human alcohol dehydrogenase at the ADH2 and ADH3 loci following DNA sequence amplification
    • Xu Y, Carr LG, Bosron WF, Li TK, Edenberg HJ: Genotyping of human alcohol dehydrogenase at the ADH2 and ADH3 loci following DNA sequence amplification. Genomics 2:209-214, 1988
    • (1988) Genomics , vol.2 , pp. 209-214
    • Xu, Y.1    Carr, L.G.2    Bosron, W.F.3    Li, T.K.4    Edenberg, H.J.5
  • 36
    • 0029929401 scopus 로고    scopus 로고
    • Investigator-observed alcohol-induced flushing but not self-report of flushing is a valid predictor of ALDH2 genotype
    • Wall TL, Thomasson HR, Ehlers CL: Investigator-observed alcohol-induced flushing but not self-report of flushing is a valid predictor of ALDH2 genotype. J Stud Alcohol 57:267-272, 1996
    • (1996) J Stud Alcohol , vol.57 , pp. 267-272
    • Wall, T.L.1    Thomasson, H.R.2    Ehlers, C.L.3
  • 37
    • 0027310370 scopus 로고
    • Genetic polymorphism of alcohol and aldehyde dehydrogenase and the effects on alcohol metabolism
    • Yamamoto K, Ueno Y, Mizoi Y, Tatsuno Y: Genetic polymorphism of alcohol and aldehyde dehydrogenase and the effects on alcohol metabolism. Japan J Alcohol Drug Depend 28:13-25, 1993
    • (1993) Japan J Alcohol Drug Depend , vol.28 , pp. 13-25
    • Yamamoto, K.1    Ueno, Y.2    Mizoi, Y.3    Tatsuno, Y.4
  • 38
    • 0026612513 scopus 로고
    • Clinical responses in relation to blood acetaldehyde levels
    • Johnsen J, Stowell A, Morland J: Clinical responses in relation to blood acetaldehyde levels. Pharmacol Toxicol 70:41-45, 1992
    • (1992) Pharmacol Toxicol , vol.70 , pp. 41-45
    • Johnsen, J.1    Stowell, A.2    Morland, J.3
  • 39
    • 0025752913 scopus 로고
    • A polymorphism in the rat liver mitochondria ALDH2 gene is associated with alcohol drinking behavior
    • Weiner H (ed). New York, Plenum Press
    • Carr L, Mellencamp B, Crabb D, Lumeng L, Li TK: A polymorphism in the rat liver mitochondria ALDH2 gene is associated with alcohol drinking behavior, in Weiner H (ed): Enzymology and Molecular Biology of Carbonyl Metabolism, ed 3. New York, Plenum Press, 1990. pp 61-65
    • (1990) Enzymology and Molecular Biology of Carbonyl Metabolism, Ed 3 , pp. 61-65
    • Carr, L.1    Mellencamp, B.2    Crabb, D.3    Lumeng, L.4    Li, T.K.5
  • 40
    • 0027996392 scopus 로고
    • Hepatic aldehyde and alcohol dehydrogenases in alcohol-preferring and alcohol avoiding rat lines
    • Koivisto T, Eriksson P: Hepatic aldehyde and alcohol dehydrogenases in alcohol-preferring and alcohol avoiding rat lines. Biochem Pharmacol 48:1551-1558, 1994
    • (1994) Biochem Pharmacol , vol.48 , pp. 1551-1558
    • Koivisto, T.1    Eriksson, P.2
  • 41
    • 0028258504 scopus 로고
    • Ethanol consumption by rats is conversely related to hepatic alcohol dehydrogenase activity
    • Keegan A, Batey R: Ethanol consumption by rats is conversely related to hepatic alcohol dehydrogenase activity. J Hepatol 9:205-206, 1994
    • (1994) J Hepatol , vol.9 , pp. 205-206
    • Keegan, A.1    Batey, R.2
  • 42
    • 0028557504 scopus 로고
    • Involvement of genetic polymorphism of alcohol and aldehyde dehydrogenases in individual variation of alcohol metabolism
    • Mizoi Y, Yamamoto K, Ueno Y, Fukunaga T, Harada S: Involvement of genetic polymorphism of alcohol and aldehyde dehydrogenases in individual variation of alcohol metabolism. Alcohol Alcohol 29:707-710, 1994
    • (1994) Alcohol Alcohol , vol.29 , pp. 707-710
    • Mizoi, Y.1    Yamamoto, K.2    Ueno, Y.3    Fukunaga, T.4    Harada, S.5
  • 43
  • 44
    • 0027499273 scopus 로고
    • Induction of P450IIEI in human liver by ethanol is due to a corresponding increase in encoding mRNA
    • Takahashi S, Lasker JM, Rosman AS, Lieber CS: Induction of P450IIEI in human liver by ethanol is due to a corresponding increase in encoding mRNA. Hepatology 17:236-245, 1993
    • (1993) Hepatology , vol.17 , pp. 236-245
    • Takahashi, S.1    Lasker, J.M.2    Rosman, A.S.3    Lieber, C.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.