Regulation of tight junction permeability by sodium caprate in human keratinocytes and reconstructed epidermis

Biochemical and Biophysical Research Communications

Volumn 381, Issue 2, 2009, Pages 171-175

  Kurasawa, Masumi ^a   Kuroda, Shohei ^a   Kida, Naoko ^a   Murata, Michiyo ^b   Oba, Ai ^a   Yamamoto, Takuya ^a   Sasaki, Hiroyuki ^b  

^a POLA CHEMICAL INDUSTRIES INC   (Japan)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Claudin 1; Human keratinocyte; Occuludin; Paracellular permeability; Reconstructed human epidermis; Sodium caprate; Tight junction

Indexed keywords

MEMBRANE PROTEIN; SODIUM;

ARTICLE; CELL MEMBRANE PERMEABILITY; CELL SURFACE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ELECTRIC RESISTANCE; ELECTRON MICROSCOPY; EMBRYO; EPIDERMIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE MICROSCOPY; INTESTINE CELL; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; TIGHT JUNCTION; WESTERN BLOTTING;

CELL LINE; CELL MEMBRANE PERMEABILITY; DECANOIC ACIDS; EPIDERMIS; HUMANS; KERATINOCYTES; MEMBRANE PROTEINS; TIGHT JUNCTIONS;

EID: 61849163889     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.02.005     Document Type: Article

References (25)

1. Furuse M., Hata M., Furuse K., Yoshida Y., Haratake A., Sugitani Y., Noda T., Kubo A., and Tsukita S. Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deffcient mice. J. Cell. Biol. 156 (2002) 1099-1111
2. Yamamoto T., Kurasawa M., Hattori T., Maeda T., Nakano H., and Sasaki H. Relationship between expression of tight junction-related molecules and perturbed epidermal barrier function in UVB-irradiated hairless mice. Arch. Dermatol. Res. 300 (2008) 61-68
3. Yamamoto T., Saeki Y., Kurasawa M., Kuroda S., Arase S., and Sasaki H. Effect of RNA interference of tight junction-related molecules on intercellular barrier function in cultured human keratinocytes. Arch. Dermatol. Res. 300 (2008) 517-524
4. Salama N.N., Eddington N.D., and Fasano A. Tight Junction and its relationship to drug delivery. Adv. Drug Deliv. Rev. 58 (2006) 15-28
5. Aungst B. Intestinal permeation enhancers. J. Pharm. Sci. 89 4 (2000) 429-442
6. LeCluyse E.L., and Sutton S.C. In vitro models for selection of development candidates. Permeability studies to define mechanisms of absorption enhancement. Adv. Drug Deliv. Rev. 23 (1997) 163-183
7. Swenson E.C., and Curatolo W.J. Intestinal permeability enhancement for proteins, peptides and other polar drugs: mechanisms and potential toxicity. Adv. Drug Deliv. Rev. 8 1 (1992) 39-92
8. Van Hoogdalem E.J., Wackwitz A.T.E., de Boer A.G., and Breimer D.D. Topical effects of absorption enhancing agents on the rectal mucosa of rats in vivo. J. Pharm. Sci. 79 10 (1990) 866-870
9. Hovgaard L., Brondsted H., and Nielsen H.M. Drug delivery studies in Caco-2 monolayers. II. Absorption enhancer effects of lysophosphatidylcholine. Int. J. Pharm. 114 (1995) 141-149
10. Shimazaki T., Tomita M., Sadahiro S., Hayashi M., and Awazu S. Absorption-enhancing effects of sodium caprate and palmitoyl carnitine in rat and human colons. Dig. Dis. Sci. 43 3 (1998) 641-645
11. Knipp G.T., Ho N.F., Barsuhn C.L., and Borchardt R.T. Paracellular diffusion in Caco-2 cell monolayers: effect of perturbation on the transport of hydrophilic compounds that vary in charge and size. J. Pharm. Sci. 86 10 (1997) 1105-1110
12. Anderberg E.K., Lindmark T., and Artursson P. Sodium caprate elicits dilatations in human intestinal tight junctions and enhances drug absorption by paracellular route. Pharm. Res. 10 (1993) 857-864
13. Tomita M., Hayashi M., and Awazu S. Absorption-enhancing mechanism of EDTA, caprate and decanoylcarnitine in Caco-2 cells. J. Pharm. Sci. 85 6 (1996) 608-611
14. Lindmark T., Kimura Y., and Artursson P. Absorption enhancement through intracellular regulation of tight junction permeability by medium chain fatty acids in Caco-2 cells. J. Pharmacol. Exp. Ther. 284 1 (1998) 362-369
15. Gan L.S., and Thakker D.R. Applications of the Caco-2 model in the design and development of orally active drugs: elucidation of biochemical and physical barriers posed by the intestinal epithelium. Adv. Drug Deliv. Rev. 23 (1997) 77-98
16. Hochman J., and Artursson P. Mechanisms of absorption enhancement and tight junction regulation. J. Control. Release 29 (1994) 253-267
17. Lindmark T., Nikkila T., and Artursson P. Mechanisms of absorption enhancement by medium chain fatty acids in intestinal epithelial Caco-2 monolayers. J. Pharmacol. Exp. Ther. 275 2 (1995) 958-964
18. Watson C.J., Rowland M., and Warhurst G. Functional modeling of tight junctions in intestinal cell monolayers using polyethylene glycol oligomers. Am. J. Physiol. Cell Physiol. 281 (2001) C388-C397
19. Tomita M., Hayashi M., and Awazu A. Absorption-enhancing mechanism of sodium caprate and decanoylcarnitine in Caco-2 cells. J. Pharmacol. Exp. Ther. 272 (1995) 739-743
20. Lindmark T., Schipper N., Lazorova L., De Boer A.G., and Artuesson P. Absorption enhancement in intestinal epithelial Caco-2 monolayers by sodium caprate: assessment of molecular weight dependence and demonstration of transport routes. J. Drug Target. 5 3 (1998) 215-223
21. Suzuki T., and Hara H. Difructose anhydride III and sodium caprate activate paracellular transport via different intracellular events in Caco-2 cells. Life Sci. 79 4 (2006) 401-410
22. Chen Y.H., Lu Q., Goodenough D.A., and Jeansonne B. Nonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine kidney epithelial cells. Mol. Biol. Cell 13 (2002) 1227-1237
23. Sasaki H. Methods in molecular medicine, renal disease, techniques and protocols. In: Goligorsky M.S. (Ed). Freeze-Fracture Analysis of Renal-Epithelial Tight Junctions (2003), Humana Press Inc., Totowa, NJ 155-166 Vol. 86
24. Matsuda M., Kubo A., Furuse M., and Tsukita S. A peculiar internalization of claudins, tight junction-specific adhesion molecules, during the intercellular movement of epithelial cells. J. Cell Sci. 117 Pt. 7 (2004) 1247-1257
25. Schneeberger E.E., and MacCormack J.M. Intercellular junctions in upper airway submucosal glands of the rat: a tracer and freeze fracture study. Anat. Rec. 210 (1984) 421-433