Absorption-enhancing mechanism of EDTA, caprate, and decanoylcarnitine in Caco-2 cells

Journal of Pharmaceutical Sciences

Volumn 85, Issue 6, 1996, Pages 608-611

  Tomita, Mikio ^a   Hayashi, Masahiro ^a,b   Awazu, Shoji ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; CALMODULIN INHIBITOR; CARNITINE DERIVATIVE; CHELATING AGENT; DECANOATE SODIUM; DEXTRAN; EDETIC ACID; FLUORESCEIN ISOTHIOCYANATE; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; PROTEIN KINASE C INHIBITOR; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ARTICLE; CALCIUM CELL LEVEL; CELL MEMBRANE PERMEABILITY; CHELATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; TIGHT JUNCTION;

EID: 0029971199     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js9504604     Document Type: Article

References (22)

1. Cassidy, M. M.; Tidball, C. S. J. Cell. Biol. 1967, 32, 685-698.
2. Tomita, M.; Shiga, M.; Hayashi, M.; Awazu, S. Pharm. Res. 1988, 5, 341-346.
3. Sawada, T.; Tomita, M.; Hayashi, M.; Awazu, S. J. Pharmacobio-Dyn. 1989, 12, 634-639.
4. Sawada, T.; Ogawa, T.; Tomita, M.; Hayashi, M.; Awazu, S. Pharm. Res. 1991, 8, 1365-1371.
5. Tomita, M.; Hayashi, M.; Awazu, S. Biol. Pharm. Bull. 1994, 17, 753-755.
6. Tomita, M.; Hayashi, M.; Awazu, S. J. Pharmacol. Exp. Ther. 1995, 272, 739-743.
7. LeCluyse, E. L.; Appe, L. E.; Sutton, S. C. Pharm. Res. 1991, 8, 84-87.
8. Sutton, S. C.; Forbes, A. E.; Cargill, R.; Hochman, J. H.; LeCluyse, E. L. Pharm. Res. 1992, 9, 316-319.
9. Yamashita, S.; Saitoh, H.; Nakanishi, K.; Masada, M.; Nadai, T.; Kimura, T. J. Pharm. Pharmacol. 1984, 37, 512-513.
10. Hu, M.; Borchardt, R. T. Pharm. Res. 1990, 7, 1313-1319.
11. Tokumitsu, H.; Chijiwa, T.; Hagiwara, M.; Mizutani, A.; Terasawa, M.; Hidaka, H. J. Biol. Chem. 1990, 265, 4315-4320.
12. Ishikawa, N.; Hashiba, Y.; Hidaka, H. J. Pharmacol. Exp. Ther. 1990, 254, 598-602.
13. Kawamoto, S.; Hidaka, H. Biochem. Biophys. Res. Commun. 1984, 125, 258-264.
14. Kanamori, M.; Naka, M.; Asano, M.; Hidaka, H. J. Pharmacol. Exp. Ther. 1981, 217, 494-499.
15. Giynkiewicz, G.; Peonie, M.; Tsien, R. Y. J. Biol. Chem. 1985, 260, 3440-3450.
16. Anderberg, E. K.; Lindmark, T.; Artursson, P. Pharm. Res. 1993, 10, 857-864.
17. Madara, J. L.; Moore, R.; Carlson, S. Am. J. Physiol. 1987, 253, C854-861.
18. Madara, J. L.; Barenberg, D.; Carlson, S. J. Cell Biol. 1986, 102, 2125-2136.
19. Citi, S. J. Cell Biol. 1992, 117, 169-178.
20. Stenson, W. F.; Easom, R. A.; Riehl, T. E.; Turk, J. Am. J. Physiol. 1993, 265, G955-962.
21. Noach, A. B. J.; Kurosaki, Y.; Blom-Roosemalen, M. C. M.; De boer, A. G.; Breimer, D. D. Int. J. Pharm. 1993, 90, 229-237.
22. Gumbiner, B. Am. J. Physiol. 1987, 253, C749-C753.