메뉴 건너뛰기




Volumn 277, Issue 1, 2009, Pages 72-81

Neuromedin U is overexpressed in pancreatic cancer and increases invasiveness via the hepatocyte growth factor c-Met pathway

Author keywords

c Met; Metastasis; Neuromedin U; Neuromedin U receptor; Pancreatic cancer

Indexed keywords

NEUROMEDIN U; NEUROMEDIN U RECEPTOR 2; RECEPTOR; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG;

EID: 61849136239     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2008.11.028     Document Type: Article
Times cited : (38)

References (51)
  • 1
    • 0022249076 scopus 로고
    • Neuromedin U-8 and U-25: novel uterus stimulating and hypertensive peptides identified in porcine spinal cord
    • Minamino N., Kangawa K., and Matsuo H. Neuromedin U-8 and U-25: novel uterus stimulating and hypertensive peptides identified in porcine spinal cord. Biochem. Biophys. Res. Commun. 130 (1985) 1078-1085
    • (1985) Biochem. Biophys. Res. Commun. , vol.130 , pp. 1078-1085
    • Minamino, N.1    Kangawa, K.2    Matsuo, H.3
  • 2
    • 0022392038 scopus 로고
    • Neuromedins: novel smooth-muscle stimulating peptides identified in porcine spinal cord
    • Minamino N., Sudoh T., Kangawa K., and Matsuo H. Neuromedins: novel smooth-muscle stimulating peptides identified in porcine spinal cord. Peptides 6 Suppl. 3 (1985) 245-248
    • (1985) Peptides , vol.6 , Issue.SUPPL. 3 , pp. 245-248
    • Minamino, N.1    Sudoh, T.2    Kangawa, K.3    Matsuo, H.4
  • 3
    • 0028923630 scopus 로고
    • Cloning and characterization of the cDNA encoding the human neuromedin U (NmU) precursor: NmU expression in the human gastrointestinal tract
    • Austin C., Lo G., Nandha K.A., Meleagros L., and Bloom S.R. Cloning and characterization of the cDNA encoding the human neuromedin U (NmU) precursor: NmU expression in the human gastrointestinal tract. J. Mol. Endocrinol. 14 (1995) 157-169
    • (1995) J. Mol. Endocrinol. , vol.14 , pp. 157-169
    • Austin, C.1    Lo, G.2    Nandha, K.A.3    Meleagros, L.4    Bloom, S.R.5
  • 4
    • 0028239660 scopus 로고
    • Distribution and developmental pattern of neuromedin U expression in the rat gastrointestinal tract
    • Austin C., Oka M., Nandha K.A., Legon S., Khandan-Nia N., Lo G., and Bloom S.R. Distribution and developmental pattern of neuromedin U expression in the rat gastrointestinal tract. J. Mol. Endocrinol. 12 (1994) 257-263
    • (1994) J. Mol. Endocrinol. , vol.12 , pp. 257-263
    • Austin, C.1    Oka, M.2    Nandha, K.A.3    Legon, S.4    Khandan-Nia, N.5    Lo, G.6    Bloom, S.R.7
  • 6
    • 0023405198 scopus 로고
    • Neuromedin U-a study of its distribution in the rat
    • Domin J., Ghatei M.A., Chohan P., and Bloom S.R. Neuromedin U-a study of its distribution in the rat. Peptides 8 (1987) 779-784
    • (1987) Peptides , vol.8 , pp. 779-784
    • Domin, J.1    Ghatei, M.A.2    Chohan, P.3    Bloom, S.R.4
  • 7
    • 0025099377 scopus 로고
    • Neuromedin U-like immunoreactivity in rat intestine: regional distribution and immunohistochemical study
    • Honzawa M., Sudoh T., Minamino N., Kangawa K., and Matsuo H. Neuromedin U-like immunoreactivity in rat intestine: regional distribution and immunohistochemical study. Neuropeptides 15 (1990) 1-9
    • (1990) Neuropeptides , vol.15 , pp. 1-9
    • Honzawa, M.1    Sudoh, T.2    Minamino, N.3    Kangawa, K.4    Matsuo, H.5
  • 11
    • 9444223919 scopus 로고    scopus 로고
    • Signaling and ligand binding by recombinant neuromedin U receptors: evidence for dual coupling to Galphaq/11 and Galphai and an irreversible ligand-receptor interaction
    • Brighton P.J., Szekeres P.G., Wise A., and Willars G.B. Signaling and ligand binding by recombinant neuromedin U receptors: evidence for dual coupling to Galphaq/11 and Galphai and an irreversible ligand-receptor interaction. Mol. Pharmacol. 66 (2004) 1544-1556
    • (2004) Mol. Pharmacol. , vol.66 , pp. 1544-1556
    • Brighton, P.J.1    Szekeres, P.G.2    Wise, A.3    Willars, G.B.4
  • 14
    • 0025259302 scopus 로고
    • Regional hemodynamic effects of endothelin-2 and sarafotoxin-S6b in conscious rats
    • Gardiner S.M., Compton A.M., and Bennett T. Regional hemodynamic effects of endothelin-2 and sarafotoxin-S6b in conscious rats. Am. J. Physiol. 258 (1990) R912-R917
    • (1990) Am. J. Physiol. , vol.258
    • Gardiner, S.M.1    Compton, A.M.2    Bennett, T.3
  • 15
    • 0023667139 scopus 로고
    • Effect of synthetic neuromedin U-8 and U-25, novel peptides identified in porcine spinal cord, on splanchnic circulation in dogs
    • Sumi S., Inoue K., Kogire M., Doi R., Takaori K., Suzuki T., Yajima H., and Tobe T. Effect of synthetic neuromedin U-8 and U-25, novel peptides identified in porcine spinal cord, on splanchnic circulation in dogs. Life Sci. 41 (1987) 1585-1590
    • (1987) Life Sci. , vol.41 , pp. 1585-1590
    • Sumi, S.1    Inoue, K.2    Kogire, M.3    Doi, R.4    Takaori, K.5    Suzuki, T.6    Yajima, H.7    Tobe, T.8
  • 19
    • 0141887005 scopus 로고    scopus 로고
    • A pro-nociceptive role of neuromedin U in adult mice
    • Cao C.Q., Yu X.H., Dray A., Filosa A., and Perkins M.N. A pro-nociceptive role of neuromedin U in adult mice. Pain 104 (2003) 609-616
    • (2003) Pain , vol.104 , pp. 609-616
    • Cao, C.Q.1    Yu, X.H.2    Dray, A.3    Filosa, A.4    Perkins, M.N.5
  • 21
    • 15044363087 scopus 로고    scopus 로고
    • Identification of L1CAM, Jagged2 and neuromedin U as ovarian cancer-associated antigens
    • Euer N.I., Kaul S., Deissler H., Mobus V.J., Zeillinger R., and Weidle U.H. Identification of L1CAM, Jagged2 and neuromedin U as ovarian cancer-associated antigens. Oncol. Rep. 13 (2005) 375-387
    • (2005) Oncol. Rep. , vol.13 , pp. 375-387
    • Euer, N.I.1    Kaul, S.2    Deissler, H.3    Mobus, V.J.4    Zeillinger, R.5    Weidle, U.H.6
  • 26
    • 0023661693 scopus 로고
    • Scatter factor is a fibroblast-derived modulator of epithelial cell mobility
    • Stoker M., Gherardi E., Perryman M., and Gray J. Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature 327 (1987) 239-242
    • (1987) Nature , vol.327 , pp. 239-242
    • Stoker, M.1    Gherardi, E.2    Perryman, M.3    Gray, J.4
  • 28
    • 0032189977 scopus 로고    scopus 로고
    • Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase
    • Birchmeier C., and Gherardi E. Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase. Trends Cell Biol. 8 (1998) 404-410
    • (1998) Trends Cell Biol. , vol.8 , pp. 404-410
    • Birchmeier, C.1    Gherardi, E.2
  • 29
    • 0037302117 scopus 로고    scopus 로고
    • HGF/SF-met signaling in the control of branching morphogenesis and invasion
    • Zhang Y.W., and Vande Woude G.F. HGF/SF-met signaling in the control of branching morphogenesis and invasion. J. Cell. Biochem. 88 (2003) 408-417
    • (2003) J. Cell. Biochem. , vol.88 , pp. 408-417
    • Zhang, Y.W.1    Vande Woude, G.F.2
  • 30
    • 0027343219 scopus 로고
    • Properties and structure-function relationship of HGF-SF
    • Gherardi E., Sharpe M., and Lane K. Properties and structure-function relationship of HGF-SF. Exs 65 (1993) 31-48
    • (1993) Exs , vol.65 , pp. 31-48
    • Gherardi, E.1    Sharpe, M.2    Lane, K.3
  • 31
    • 0027830892 scopus 로고
    • Hepatocyte growth factor/scatter factor (HGF/SF), the c-met receptor and the behaviour of epithelial cells
    • Gherardi E., Sharpe M., Lane K., Sirulnik A., and Stoker M. Hepatocyte growth factor/scatter factor (HGF/SF), the c-met receptor and the behaviour of epithelial cells. Symp. Soc. Exp. Biol. 47 (1993) 163-181
    • (1993) Symp. Soc. Exp. Biol. , vol.47 , pp. 163-181
    • Gherardi, E.1    Sharpe, M.2    Lane, K.3    Sirulnik, A.4    Stoker, M.5
  • 33
    • 0027939437 scopus 로고
    • Coexpression of the c-met proto-oncogene and hepatocyte growth factor in human pancreatic cancer
    • Ebert M., Yokoyama M., Friess H., Buchler M.W., and Korc M. Coexpression of the c-met proto-oncogene and hepatocyte growth factor in human pancreatic cancer. Cancer Res. 54 (1994) 5775-5778
    • (1994) Cancer Res. , vol.54 , pp. 5775-5778
    • Ebert, M.1    Yokoyama, M.2    Friess, H.3    Buchler, M.W.4    Korc, M.5
  • 34
    • 0028801180 scopus 로고
    • Hepatocyte growth factor and Met receptor expression in human pancreatic carcinogenesis
    • Furukawa T., Duguid W.P., Kobari M., Matsuno S., and Tsao M.S. Hepatocyte growth factor and Met receptor expression in human pancreatic carcinogenesis. Am. J. Pathol. 147 (1995) 889-895
    • (1995) Am. J. Pathol. , vol.147 , pp. 889-895
    • Furukawa, T.1    Duguid, W.P.2    Kobari, M.3    Matsuno, S.4    Tsao, M.S.5
  • 35
    • 21744434389 scopus 로고    scopus 로고
    • Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis
    • Erkan M., Kleeff J., Esposito I., Giese T., Ketterer K., Buchler M.W., Giese N.A., and Friess H. Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis. Oncogene 24 (2005) 4421-4432
    • (2005) Oncogene , vol.24 , pp. 4421-4432
    • Erkan, M.1    Kleeff, J.2    Esposito, I.3    Giese, T.4    Ketterer, K.5    Buchler, M.W.6    Giese, N.A.7    Friess, H.8
  • 37
    • 0242610430 scopus 로고    scopus 로고
    • Reverse transcription-PCR analysis of laser-captured cells points to potential paracrine and autocrine actions of neurotrophins in pancreatic cancer
    • Ketterer K., Rao S., Friess H., Weiss J., Buchler M.W., and Korc M. Reverse transcription-PCR analysis of laser-captured cells points to potential paracrine and autocrine actions of neurotrophins in pancreatic cancer. Clin. Cancer. Res. 9 (2003) 5127-5136
    • (2003) Clin. Cancer. Res. , vol.9 , pp. 5127-5136
    • Ketterer, K.1    Rao, S.2    Friess, H.3    Weiss, J.4    Buchler, M.W.5    Korc, M.6
  • 41
    • 0036204021 scopus 로고    scopus 로고
    • Microarray data warehouse allowing for inclusion of experiment annotations in statistical analysis
    • Fellenberg K., Hauser N.C., Brors B., Hoheisel J.D., and Vingron M. Microarray data warehouse allowing for inclusion of experiment annotations in statistical analysis. Bioinformatics 18 (2002) 423-433
    • (2002) Bioinformatics , vol.18 , pp. 423-433
    • Fellenberg, K.1    Hauser, N.C.2    Brors, B.3    Hoheisel, J.D.4    Vingron, M.5
  • 46
    • 4344628907 scopus 로고    scopus 로고
    • Inverse correlation between cyclin A1 hypermethylation and p53 mutation in head and neck cancer identified by reversal of epigenetic silencing
    • Tokumaru Y., Yamashita K., Osada M., Nomoto S., Sun D.I., Xiao Y., Hoque M.O., Westra W.H., Califano J.A., and Sidransky D. Inverse correlation between cyclin A1 hypermethylation and p53 mutation in head and neck cancer identified by reversal of epigenetic silencing. Cancer Res. 64 (2004) 5982-5987
    • (2004) Cancer Res. , vol.64 , pp. 5982-5987
    • Tokumaru, Y.1    Yamashita, K.2    Osada, M.3    Nomoto, S.4    Sun, D.I.5    Xiao, Y.6    Hoque, M.O.7    Westra, W.H.8    Califano, J.A.9    Sidransky, D.10
  • 47
    • 33846846542 scopus 로고    scopus 로고
    • Neuromedin U is regulated by the metastasis suppressor RhoGDI2 and is a novel promoter of tumor formation, lung metastasis and cancer cachexia
    • Wu Y., McRoberts K., Berr S.S., Frierson Jr. H.F., Conaway M., and Theodorescu D. Neuromedin U is regulated by the metastasis suppressor RhoGDI2 and is a novel promoter of tumor formation, lung metastasis and cancer cachexia. Oncogene 26 (2007) 765-773
    • (2007) Oncogene , vol.26 , pp. 765-773
    • Wu, Y.1    McRoberts, K.2    Berr, S.S.3    Frierson Jr., H.F.4    Conaway, M.5    Theodorescu, D.6
  • 51
    • 33847107185 scopus 로고    scopus 로고
    • Neuromedin U can exert colon-specific, enteric nerve-mediated prokinetic activity, via a pathway involving NMU1 receptor activation
    • Dass N.B., Bassil A.K., North-Laidler V.J., Morrow R., Aziz E., Tuladhar B.R., and Sanger G.J. Neuromedin U can exert colon-specific, enteric nerve-mediated prokinetic activity, via a pathway involving NMU1 receptor activation. Brit. J. Pharmacol. 150 (2007) 502-508
    • (2007) Brit. J. Pharmacol. , vol.150 , pp. 502-508
    • Dass, N.B.1    Bassil, A.K.2    North-Laidler, V.J.3    Morrow, R.4    Aziz, E.5    Tuladhar, B.R.6    Sanger, G.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.