Neurokinin-2 receptor levels correlate with intensity, frequency, and duration of pain in chronic pancreatitis

Annals of Surgery

Volumn 246, Issue 5, 2007, Pages 786-793

  Michalski, Christoph W ^a,e   Shi, Xin ^a   Reiser, Carolin ^a,e   Fachinger, Patrick ^b   Zimmermann, Arthur ^c   Büchler, Markus W ^a   Di Sebastiano, Pierluigi ^d   Friess, Helmut ^a,e  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF BERN   (Switzerland)

^c UNIVERSITY OF BERN   (Switzerland)

^d CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EOSIN; HEMATOXYLIN; MEMBRANE METALLOENDOPEPTIDASE; MESSENGER RNA; NEUROKININ 1 RECEPTOR; NEUROKININ 2 RECEPTOR; NEUROKININ 3 RECEPTOR; PREPROTACHYKININ; SUBSTANCE P;

ADULT; AGED; ARTICLE; CHRONIC PANCREATITIS; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYSTIC FIBROSIS; DISEASE DURATION; DISEASE EXACERBATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; PAIN; PAIN PARAMETERS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCORING SYSTEM; STAINING;

ABDOMINAL PAIN; ADULT; AGED; CASE-CONTROL STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; NEPRILYSIN; PAIN MEASUREMENT; PANCREATITIS, CHRONIC; PROTEIN PRECURSORS; RECEPTORS, NEUROKININ-2; RECEPTORS, NEUROKININ-3; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TACHYKININS; TIME FACTORS;

EID: 35648949366     PISSN: 00034932     EISSN: None     Source Type: Journal    
DOI: 10.1097/SLA.0b013e318070d56e     Document Type: Article

References (28)

1. Sidhu S, Tandon RK. Chronic pancreatitis: diagnosis and treatment. Postgrad Med J. 1996;72:327-333.
2. Bradley EL 3rd. Pancreatic duct pressure in chronic pancreatitis. Am J Surg. 1982;144:313-316.
3. Di Sebastiano P, di Mola FF, Buchler MW, et al. Pathogenesis of pain in chronic pancreatitis. Dig Dis. 2004;22:267-272.
4. Bockman DE, Buchler M, Malfertheiner P, et al. Analysis of nerves in chronic pancreatitis. Gastroenterology. 1988;94:1459-1469.
5. Buchler M, Weihe E, Friess H, et al. Changes in peptidergic innervation in chronic pancreatitis. Pancreas. 1992;7:183-192.
6. Di Sebastiano P, Fink T, Weihe E, et al. Immune cell infiltration and growth-associated protein 43 expression correlate with pain in chronic pancreatitis. Gastroenterology. 1997;112:1648-1655.
7. Friess H, Zhu ZW, di Mola FF, et al. Nerve growth factor and its high-affinity receptor in chronic pancreatitis. Ann Surg. 1999;230:615-624.
8. Di Sebastiano P, di Mola FF, Di Febbo C, et al. Expression of interleukin 8 (IL-8) and substance P in human chronic pancreatitis. Gut. 2000;47:423-428.
9. Duggan AW, Hendry IA, Morton CR, et al. Cutaneous stimuli releasing immunoreactive substance P in the dorsal horn of the cat. Brain Res. 1988;451:261-273.
10. Ma QP, Woolf CJ. Involvement of neurokinin receptors in the induction but not the maintenance of mechanical allodynia in rat flexor motoneurones. J Physiol. 1995;486:769-777.
11. Cao YQ, Mantyh PW, Carlson EJ, et al. Primary afferent tachykinins are required to experience moderate to intense pain. Nature. 1998;392:390-394.
12. Debeljuk L, Lasaga M. Modulation of the hypothalamo-pituitary-gonadal axis and the pineal gland by neurokinin A, neuropeptide K and neuropeptide gamma. Peptides. 1999;20:285-299.
13. Maggio JE. Tachykinins. Annu Rev Neurosci. 1988;11:13-28.
14. Shrikhande SV, Friess H, di Mola FF, et al. NK-1 receptor gene expression is related to pain in chronic pancreatitis. Pain. 2001;91:209-217.
15. Buchler MW, Friess H, Bittner R, et al. Duodenum-preserving pancreatic head resection: long-term results. J Gastrointest Surg. 1997;1:13-19.
16. Friess H, Yamanaka Y, Buchler M, et al. Enhanced expression of the type II transforming growth factor beta receptor in human pancreatic cancer cells without alteration of type III receptor expression. Cancer Res. 1993;53:2704-2707.
17. Heid CA, Stevens J, Livak KJ, et al. Real time quantitative PCR. Genome Res. 1996;6:986-994.
18. Conejo JR, Kleeff J, Koliopanos A, et al. Syndecan-1 expression is up-regulated in pancreatic but not in other gastrointestinal cancers. Int J Cancer. 2000;88:12-20.
19. Wang L, Friess H, Zhu Z, et al. Galectin-1 and galectin-3 in chronic pancreatitis. Lab Invest. 2000;80:1233-1241.
20. Friess H, Wang L, Zhu Z, et al. Growth factor receptors are differentially expressed in cancers of the papilla of Vater and pancreas. Ann Surg. 1999;230:767-774; discussion 774-775.
21. Ammann RW, Heitz PU, Kloppel G. Course of alcoholic chronic pancreatitis: a prospective clinicomorphological long-term study. Gastroenterology. 1996;111:224-231.
22. Cooper MJ, Williamson RC. Drainage operations in chronic pancreatitis. Br J Surg. 1984;71:761-766.
23. Holzer P, Holzer-Petsche U. Tachykinins in the gut: I. Expression, release and motor function. Pharmacol Ther. 1997;73:173-217.
24. Quirion R, Dam TV. Multiple tachykinin receptors in guinea pig brain: high densities of substance K (neurokinin A) binding sites in the substantia nigra. Neuropeptides. 1985;6:191-204.
25. Ness TJ, Gebhart GF. Inflammation enhances reflex and spinal neuron responses to noxious visceral stimulation in rats. Am J Physiol Gastrointest Liver Physiol. 2001;280:G649-G657.
26. Schwei MJ, Honore P, Rogers SD, et al. Neurochemical and cellular reorganization of the spinal cord in a murine model of bone cancer pain. J Neurosci. 1999;19:10886-10897.
27. Grady EF, Yoshimi SK, Maa J, et al. Substance P mediates inflammatory oedema in acute pancreatitis via activation of the neurokinin-1 receptor in rats and mice. Br J Pharmacol. 2000;130:505-512.
28. Kirkwood KS, Kim EH, He XD, et al. Substance P inhibits pancreatic exocrine secretion via a neural mechanism. Am J Physiol. 1999;277:G314-G320.