Neuromedin U can exert colon-specific, enteric nerve-mediated prokinetic activity, via a pathway involving NMU 1 receptor activation

British Journal of Pharmacology

Volumn 150, Issue 4, 2007, Pages 502-508

  Dass, N B ^a   Bassil, A K ^a   North Laidler, V J ^a   Morrow, R ^a   Aziz, E ^b   Tuladhar, B R ^b   Sanger, G J ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b UNIVERSITY OF BRADFORD   (United Kingdom)

Author keywords

Enteric nervous system; Motility; Neuromedin U; NMU 2R ; Peristalsis; Prokinetic

Indexed keywords

ATROPINE; NEUROMEDIN U; NEUROMEDIN U 1 RECEPTOR; RECEPTOR; TETRODOTOXIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLON; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTROSTIMULATION; EMBRYO; FECES; FORESTOMACH; GASTROINTESTINAL MOTILITY; INTESTINE INNERVATION; KNOCKOUT MOUSE; MALE; MOUSE; MUSCLE CONTRACTION; MUSCLE TONE; NONHUMAN; PERISTALSIS; PRIORITY JOURNAL; WILD TYPE;

ANIMALS; ATROPINE; COLON; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; ENTERIC NERVOUS SYSTEM; FECES; GASTROINTESTINAL MOTILITY; GUINEA PIGS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCARINIC ANTAGONISTS; MUSCLE CONTRACTION; NEUROPEPTIDES; PERISTALSIS; RECEPTORS, NEUROTRANSMITTER; SIGNAL TRANSDUCTION; TETRODOTOXIN;

EID: 33847107185     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707004     Document Type: Article

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