The neuropeptide neuromedin U promotes IL-6 production from macrophages and endotoxin shock

Biochemical and Biophysical Research Communications

Volumn 341, Issue 4, 2006, Pages 1149-1154

  Moriyama, Maiko ^a,b   Matsukawa, Akihiro ^c,d   Kudoh, Shinji ^c   Takahashi, Tomoko ^a   Sato, Takahiro ^a   Kano, Tatsuhiko ^b   Yoshimura, Akihiko ^e   Kojima, Masayasu ^a  

^a KURUME UNIVERSITY   (Japan)

^b KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KUMAMOTO UNIVERSITY   (Japan)

^d OKAYAMA UNIVERSITY   (Japan)

^e KYUSHU UNIVERSITY   (Japan)

Author keywords

Cecal ligation puncture; IL 6; Lipopolysaccharide; Macrophages; Neuromedin U

Indexed keywords

ENDOTOXIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NEUROMEDIN U; NEUROPEPTIDE; NEUROPEPTIDE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; CECUM; CONTROLLED STUDY; DOWN REGULATION; LIGATION; MACROPHAGE; MOUSE; NONHUMAN; PARACRINE SIGNALING; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPTIC SHOCK; UPREGULATION; WILD TYPE;

ANIMALS; CECUM; INTERLEUKIN-6; LIGATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, KNOCKOUT; NEUROPEPTIDES; PUNCTURES; SHOCK, SEPTIC;

ANIMALIA;

EID: 32344438877     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.01.075     Document Type: Article

References (27)

1. N. Minamino, K. Kangawa, and H. Matsuo Neuromedin U-8 and U-25: novel uterus stimulating and hypertensive peptides identified in porcine spinal cord Biochem. Biophys. Res. Commun. 130 1985 1078 1085
2. A.D. Howard, R. Wang, S.S. Pong, T.N. Mellin, A. Strack, X.M. Guan, Z. Zeng, D.L. Williams Jr., S.D. Feighner, C.N. Nunes, B. Murphy, J.N. Stair, H. Yu, Q. Jiang, M.K. Clements, C.P. Tan, K.K. McKee, D.L. Hreniuk, T.P. McDonald, K.R. Lynch, J.F. Evans, C.P. Austin, C.T. Caskey, L.H. Van der Ploeg, and Q. Liu Identification of receptors for neuromedin U and its role in feeding Nature 406 2000 70 74
3. K. Nakahara, M. Kojima, R. Hanada, Y. Egi, T. Ida, M. Miyazato, K. Kangawa, and N. Murakami Neuromedin U is involved in nociceptive reflexes and adaptation to environmental stimuli in mice Biochem. Biophys. Res. Commun. 323 2004 615 620
4. M. Moriyama, H. Furue, T. Katafuchi, H. Teranishi, T. Sato, T. Kano, M. Kojima, and M. Yoshimura Presynaptic modulation by neuromedin U of sensory synaptic transmission in rat spinal dorsal horn neurones J. Physiol. 559 2004 707 713
5. P.J. Brighton, P.G. Szekeres, A. Wise, and G.B. Willars Signaling and ligand binding by recombinant neuromedin U receptors: evidence for dual coupling to Galphaq/11 and Galphai and an irreversible ligand-receptor interaction Mol. Pharmacol. 66 2004 1544 1556
6. J.A. Hedrick, K. Morse, L. Shan, X. Qiao, L. Pang, S. Wang, T. Laz, E.L. Gustafson, M. Bayne, and F.J. Monsma Jr. Identification of a human gastrointestinal tract and immune system receptor for the peptide neuromedin U Mol. Pharmacol. 58 2000 870 875
7. E.N. Johnson, E.R. Appelbaum, D.C. Carpenter, R.F. Cox, J. Disa, J.J. Foley, S.K. Ghosh, D.P. Naselsky, M.A. Pullen, H.M. Sarau, S.R. Scheff, K.M. Steplewski, M. Zaks-Zilberman, and N. Aiyar Neuromedin U elicits cytokine release in murine Th2-type T cell clone D10.G4.1 J. Immunol. 173 2004 7230 7238
8. M. Moriyama, T. Sato, H. Inoue, S. Fukuyama, H. Teranishi, K. Kangawa, T. Kano, A. Yoshimura, and M. Kojima The neuropeptide neuromedin U promotes inflammation by direct activation of mast cells J. Exp. Med. 202 2005 217 224
9. P. Naveilhan, H. Hassani, G. Lucas, K.H. Blakeman, J.X. Hao, X.J. Xu, Z. Wiesenfeld-Hallin, P. Thoren, and P. Ernfors Reduced antinociception and plasma extravasation in mice lacking a neuropeptide Y receptor Nature 409 2001 513 517
10. R. Suzuki, T. Furuno, D.M. McKay, D. Wolvers, R. Teshima, M. Nakanishi, and J. Bienenstock Direct neurite-mast cell communication in vitro occurs via the neuropeptide substance P J. Immunol. 163 1999 2410 2415
11. M. Levite, L. Cahalon, R. Hershkoviz, L. Steinman, and O. Lider Neuropeptides, via specific receptors, regulate T cell adhesion to fibronectin J. Immunol. 160 1998 993 1000
12. M. Delgado, W. Sun, J. Leceta, and D. Ganea VIP and PACAP differentially regulate the costimulatory activity of resting and activated macrophages through the modulation of B7.1 and B7.2 expression J. Immunol. 163 1999 4213 4223
13. T. Kincy-Cain, and K.L. Bost Substance P-induced IL-12 production by murine macrophages J. Immunol. 158 1997 2334 2339
14. C. Martinez, C. Abad, M. Delgado, A. Arranz, M.G. Juarranz, N. Rodriguez-Henche, P. Brabet, J. Leceta, and R.P. Gomariz Anti-inflammatory role in septic shock of pituitary adenylate cyclase-activating polypeptide receptor Proc. Natl. Acad. Sci. USA 99 2002 1053 1058
15. C. Martinez, Y. Juarranz, C. Abad, A. Arranz, B.G. Miguel, F. Rosignoli, J. Leceta, and R.P. Gomariz Analysis of the role of the PAC1 receptor in neutrophil recruitment, acute-phase response, and nitric oxide production in septic shock J. Leukoc. Biol. 77 2005 729 738
16. R. Hanada, H. Teranishi, J.T. Pearson, M. Kurokawa, H. Hosoda, N. Fukushima, Y. Fukue, R. Serino, H. Fujihara, Y. Ueta, M. Ikawa, M. Okabe, N. Murakami, M. Shirai, H. Yoshimatsu, K. Kangawa, and M. Kojima Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway Nat. Med. 10 2004 1067 1073
17. A. Matsukawa, C.M. Hogaboam, N.W. Lukacs, P.M. Lincoln, H.L. Evanoff, R.M. Strieter, and S.L. Kunkel Expression and contribution of endogenous IL-13 in an experimental model of sepsis J. Immunol. 164 2000 2738 2744
18. A. Matsukawa, C.M. Hogaboam, N.W. Lukacs, P.M. Lincoln, R.M. Strieter, and S.L. Kunkel Endogenous monocyte chemoattractant protein-1 (MCP-1) protects mice in a model of acute septic peritonitis: cross-talk between MCP-1 and leukotriene B4 J. Immunol. 163 1999 6148 6154
19. A. Matsukawa, C.M. Hogaboam, N.W. Lukacs, P.M. Lincoln, H.L. Evanoff, and S.L. Kunkel Pivotal role of the CC chemokine, macrophage-derived chemokine, in the innate immune response J. Immunol. 164 2000 5362 5368
20. W.C. Aird The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome Blood 101 2003 3765 3777
21. D.C. Morrison, and J.L. Ryan Endotoxins and disease mechanisms Annu. Rev. Med. 38 1987 417 432
22. R. Karima, S. Matsumoto, H. Higashi, and K. Matsushima The molecular pathogenesis of endotoxic shock and organ failure Mol. Med. Today 5 1999 123 132
23. C.D. Huang, A.J. Ammit, O. Tliba, H.P. Kuo, R.B. Penn, R.A. Panettieri Jr., and Y. Amrani G-protein-coupled receptor agonists differentially regulate basal or tumor necrosis factor-alpha-stimulated activation of interleukin-6 and RANTES in human airway smooth muscle cells J. Biomed. Sci. 12 2005 763 776
24. M. Yamamoto, S. Yamazaki, S. Uematsu, S. Sato, H. Hemmi, K. Hoshino, T. Kaisho, H. Kuwata, O. Takeuchi, K. Takeshige, T. Saitoh, S. Yamaoka, N. Yamamoto, S. Yamamoto, T. Muta, K. Takeda, and S. Akira Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta Nature 430 2004 218 222
25. M.K. Dahle, G. Overland, A.E. Myhre, J.F. Stuestol, T. Hartung, C.D. Krohn, O. Mathiesen, J.E. Wang, and A.O. Aasen The phosphatidylinositol 3-kinase/protein kinase B signaling pathway is activated by lipoteichoic acid and plays a role in Kupffer cell production of interleukin-6 (IL-6) and IL-10 Infect Immun. 72 2004 5704 5711
26. L.C. Casey, R.A. Balk, and R.C. Bone Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome Ann. Intern. Med. 119 1993 771 778
27. G.H. Fey, M. Hattori, G. Hocke, T. Brechner, G. Baffet, M. Baumann, H. Baumann, and W. Northemann Gene regulation by interleukin 6 Biochimie 73 1991 47 50