HNF4alpha and HNF1alpha dysfunction as a molecular rational for cyclosporine induced posttransplantation diabetes mellitus

PLoS ONE

Volumn 4, Issue 3, 2009, Pages

  Borlak, Jürgen ^a   Niehof, Monika ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN C2; CYCLOSPORIN; CYCLOSPORIN A; FRUCTOSE BISPHOSPHATE ALDOLASE; FRUCTOSE BISPHOSPHATE ALDOLASE B; GLYCEROL KINASE; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; INSULIN; INSULIN 1; INSULIN 2; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PYRUVATE KINASE; TACROLIMUS; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; HEPATOCYTE NUCLEAR FACTOR 4; HNF4A PROTEIN, HUMAN; HNF4B PROTEIN, HUMAN; PRIMER DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CELL LINE; CELL STRAIN CACO 2; CONTROLLED STUDY; DIABETES MELLITUS; DNA BINDING; ENZYME REPRESSION; GENE EXPRESSION REGULATION; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; INSULINOMA; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; POSTTRANSPLANTATION DIABETES MELLITUS; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; RISK FACTOR; SIGNAL TRANSDUCTION; ZUCKER DIABETIC FATTY RAT; ANIMAL; EXPERIMENTAL DIABETES MELLITUS; GEL MOBILITY SHIFT ASSAY; GENETICS; PHOSPHORYLATION; PHYSIOLOGY; PROMOTER REGION; WESTERN BLOTTING;

ANIMALIA; RATTUS;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE; CYCLOSPORINE; DIABETES MELLITUS, EXPERIMENTAL; DNA PRIMERS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HEPATOCYTE NUCLEAR FACTOR 4; HUMANS; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; RATS;

EID: 61849135713     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004662     Document Type: Article

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