Antioxidative effect of the herbal remedy Qin Huo Yi Hao and its active component tetramethylpyrazine on high glucose-treated endothelial cells

Life Sciences

Volumn 84, Issue 13-14, 2009, Pages 428-436

  Kang, Yingxiu ^a   Hu, Minghua ^b   Zhu, Yanhui ^b   Gao, Xin ^a   Wang, Ming Wei ^b  

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Endothelial cells; Nitric oxide (NO); Oxidative stress; Tetramethylpyrazine (TMP); Traditional Chinese medicine

Indexed keywords

ACETOPHENONE DERIVATIVE; BIOLOGICAL MARKER; CHINESE DRUG; CHLOROGENIC ACID; CROCIN; DEACETYLASPERULOSIDIC ACID METHYL ESTER; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ESTER DERIVATIVE; FERULIC ACID; GENIPIN; GENIPOSIDE; GLUCOSE; HESPERIDIN; MESSENGER RNA; NITRIC OXIDE; PROTEIN KINASE B; PUERARIN; QIN HUO YI HAO; REACTIVE OXYGEN METABOLITE; SAPONIN; SMALL INTERFERING RNA; TETRAMETHYLPYRAZINE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 2;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN BLOOD VESSEL; CELL DAMAGE; CELL PROTECTION; CHINESE HERB; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG SYNTHESIS; ENDOTHELIUM CELL; FLUORESCENCE; GENE SILENCING; HUMAN; HUMAN CELL; MICROVASCULATURE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WESTERN BLOTTING;

ANTIOXIDANTS; BLOTTING, WESTERN; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GLUCOSE; HUMANS; ION CHANNELS; MITOCHONDRIAL PROTEINS; NITRIC OXIDE; OXIDATIVE STRESS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PYRAZINES; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS;

EID: 61849134441     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2009.01.003     Document Type: Article

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