The effect of high glucose on NO and O 2 - through endothelial GTPCH1 and NADPH oxidase

Life Sciences

Volumn 75, Issue 26, 2004, Pages 3185-3194

  Ding, Qunfang ^a,b   Hayashi, Toshio ^a   Packiasamy, Ar Juliet ^a   Miyazaki, Asaka ^a   Fukatsu, Akiko ^a   Shiraishi, Hiroaki ^c   Nomura, Takahide ^c   Iguchi, Akihisa ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b WEST CHINA UNIVERSITY OF MEDICAL SCIENCES   (China)

^c FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Aminoguanidine; Apocynin; BH 4; eNOS dysfunction; GTPCH1 activity; HMG CoA reductase inhibiters; L NAME; Superoxide anion

Indexed keywords

ATORVASTATIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENZYME INHIBITOR; GLUCOSE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; OXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TETRAHYDROBIOPTERIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; NONHUMAN;

ANIMALS; BIOPTERIN; BLOTTING, WESTERN; CATTLE; ENDOTHELIAL CELLS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOSE; GTP CYCLOHYDROLASE; HEPTANOIC ACIDS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; NADPH OXIDASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; OXYGEN; PYRROLES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STATISTICS, NONPARAMETRIC;

EID: 5444226475     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.06.005     Document Type: Article

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